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Carole Tonetti
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Journal Articles

JAK2 and MPL protein levels determine TPO-induced megakaryocyte proliferation vs differentiation

Rodolphe Besancenot, Damien Roos-Weil, Carole Tonetti, Hadjer Abdelouahab, Catherine Lacout, Florence Pasquier, Christophe Willekens, Philippe Rameau, Yann Lecluse, Jean-Baptiste Micol, Stefan N. Constantinescu, William Vainchenker, Eric Solary, Stéphane Giraudier
Journal: Blood
Blood (2014) 124 (13): 2104–2115.
https://doi.org/10.1182/blood-2014-03-559815
Published: 2014
Includes: Supplemental data
Journal Articles

Expression level and differential JAK2-V617F–binding of the adaptor protein Lnk regulates JAK2-mediated signals in myeloproliferative neoplasms

Fanny Baran-Marszak, Hajer Magdoud, Christophe Desterke, Anabell Alvarado, Claudine Roger, Stéphanie Harel, Elizabeth Mazoyer, Bruno Cassinat, Sylvie Chevret, Carole Tonetti, Stéphane Giraudier, Pierre Fenaux, Florence Cymbalista, Nadine Varin-Blank, Marie-Caroline Le Bousse-Kerdilès, Jean-Jacques Kiladjian, Laura Velazquez
Journal: Blood
Blood (2010) 116 (26): 5961–5971.
https://doi.org/10.1182/blood-2009-12-256768
Published: 2010
Includes: Supplemental data
Journal Articles

Interferon-Alpha Preferentially Targets JAK2V617F-Positive Rather Than Wild-Type Early Progenitor Cells in Myeloproliferative Disorders.

Florence Pasquier, Carole Tonetti, Rodolphe Besancenot, Bruno Cassinat, Pharm.D, Jean-Jacques Kiladjian, MD, PhD, Olivier Herault, MD, PhD, MSc, Philippe Rameau, Catherine Lacout, Jean-Luc Villeval, William Vainchenker, MD, PhD, Ronan Chaligné, Stephane Giraudier
Journal: Blood
Blood (2009) 114 (22): 436.
https://doi.org/10.1182/blood.V114.22.436.436
Published: 2009
Journal Articles

FLT3-Mediated MAPK Activation Participates in the Control of Megakaryopoiesis in Primary Myelofibrosis.

Christophe Desterke, Chrystele Bilhou-Nabera, MD, PhD, Bernadette Guerton, Carole Tonetti, Denis Clay, Olivier Pierre-Louis, Alessandro M Vannucchi, MD, PhD, Heinz Gisslinger, MD, PhD, Dominique Bordessoule, MD, PhD, Hans C Hasselbalch, MD, PhD, Vladimir Lazar, PhD, William Vainchenker, MD, PhD, Annelise Bennaceur-Griscelli, MD, PhD, Stéphane Giraudier, MD, PhD, Marie-Caroline Le Bousse-Kerdilès, PhD
Journal: Blood
Blood (2009) 114 (22): 963.
https://doi.org/10.1182/blood.V114.22.963.963
Published: 2009
Journal Articles

SOCS3 Promoter Methylation Is Not Involved in Primitive Myelofibrosis Megakaryocytic Spontaneous Growth

Ronan Chaligné, Carole Tonetti, Rodolphe Besancenot, Jean-Jacques Kiladjian, Gerard Socie, Dominique Bordessoule, William Vainchenker, Stéphane Giraudier
Journal: Blood
Blood (2008) 112 (11): 3716.
https://doi.org/10.1182/blood.V112.11.3716.3716
Published: 2008
Journal Articles

The impact of JAK2 and MPL mutations on diagnosis and prognosis of splanchnic vein thrombosis: a report on 241 cases

Clinical Trials & Observations
Jean-Jacques Kiladjian, Francisco Cervantes, Franck W. G. Leebeek, Christophe Marzac, Bruno Cassinat, Sylvie Chevret, Dominique Cazals-Hatem, Aurélie Plessier, Juan-Carlos Garcia-Pagan, Sarwa Darwish Murad, Sebastian Raffa, Harry L. A. Janssen, Claude Gardin, Sophie Cereja, Carole Tonetti, Stéphane Giraudier, Bertrand Condat, Nicole Casadevall, Pierre Fenaux, Dominique C. Valla
Journal: Blood
Blood (2008) 111 (10): 4922–4929.
https://doi.org/10.1182/blood-2007-11-125328
Published: 2008
Journal Articles

FLT3 Mediated MAPK Activation Participates in the Control of Megakaryopoiesis in Primary Myelofibrosis

Christophe Desterke, Hans Hasselbalch, MD, PHD, Dominique Bordessoule, MD, PhD, Heinz Gisslinger, MD, PhD, Alessandro Vannucchi, MD, PhD, Olivier Pierre-Louis, Carole Tonetti, Philippe Dessen, PhD, Vladimir Lazar, MD, PhD, Bernadette Guerton, Denis Clay, William Vainchenker, MD, PhD, Stephane Giraudier, MD, PhD, Marie-Caroline Le Bousse-Kerdiles, PhD
Journal: Blood
Blood (2007) 110 (11): 1532.
https://doi.org/10.1182/blood.V110.11.1532.1532
Published: 2007
Journal Articles

Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis

Ronan Chaligné, Chloé James, Carole Tonetti, Rodolphe Besancenot, Jean Pierre Le Couédic, Fanny Fava, Fréderic Mazurier, Isabelle Godin, Karim Maloum, Frédéric Larbret, Yann Lécluse, William Vainchenker, Stéphane Giraudier
Journal: Blood
Blood (2007) 110 (10): 3735–3743.
https://doi.org/10.1182/blood-2007-05-089003
Published: 2007
Journal Articles

Evidence That the MPL 515L and 515K Mutations Occur in a Lympho-Myeloid Progenitor in Idiopathic Myelofibrosis and Are Associated with TPO Hypersensitivity.

Ronan Chaligne, Jean-Pierre Le Couedic, sRA, Carole Tonetti, sRA, Rodolphe Besancenot, MD, Orianne Wagner-Ballon, MD, PhD, Najet Debili, PhD, William Vainchenker, MD, PhD, Stephane Giraudier, MD, PhD
Journal: Blood
Blood (2006) 108 (11): 117.
https://doi.org/10.1182/blood.V108.11.117.117
Published: 2006
Journal Articles

Evidence that the JAK2 G1849T (V617F) mutation occurs in a lymphomyeloid progenitor in polycythemia vera and idiopathic myelofibrosis

François Delhommeau, Sabrina Dupont, Carole Tonetti, Aline Massé, Isabelle Godin, Jean-Pierre Le Couedic, Najet Debili, Patrick Saulnier, Nicole Casadevall, William Vainchenker, Stéphane Giraudier
Journal: Blood
Blood (2006) 109 (1): 71–77.
https://doi.org/10.1182/blood-2006-03-007146
Published: 2006
Includes: Supplemental data
Journal Articles

Microarray Functional Comparison of CD34 + and Megakaryocytic Cell Transcriptomes in Myeloid Metaplasia with Myelofibrosis.

Marie-Caroline Le Bousse-Kerdiles, PhD, Christophe Desterke, Carole Tonetti, Philippe Dessen, PhD, Hugues Ripoche, Vladimir Lazar, PhD, MD, Bernadette Guerton, Denis Clay, William Vainchenker, PhD, MD, Stephane Giraudier, PhD, MD, Members of the French Inserm GEM European EUMNET Networks
Journal: Blood
Blood (2005) 106 (11): 3505.
https://doi.org/10.1182/blood.V106.11.3505.3505
Published: 2005