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Satoshi Iyama
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Journal Articles

AML-Mrg Mutation Spectrum and Its Prognosis: A Japanese Multicenter Study HM01-02 Analysis with Full Analysis Sets

Naoko Hosono, Tomoki Naito, Sunggi Chi, Hironori Arai, Koichi Onodera, Kentaro Fukushima, Daisuke Ikeda, Satoshi Iyama, Akihiko Gotoh, Takayuki Ikezoe, Naoto Takahashi, Kensuke Kojima, Junya Kanda, Koji Izutsu, Suguru Fukuhara, Hirotaka Matsui, Goichi Yoshimoto, Junya Kuroda, Takahiro Yamauchi, Kensuke Usuki, Yosuke Minami
Journal: Blood
Blood (2024) 144 (Supplement 1): 6123.
https://doi.org/10.1182/blood-2024-202327
Published: 2024
Journal Articles

Evaluation of Venetoclax Duration in Venetoclax-Azacitidine Regimen for Untreated Acute Myeloid Leukemia: Real World Experience from Hokkaido Leukemia Net

Minoru Kanaya, Masahiro Onozawa, Toshihiro Matsukawa, Naoki Miyashita, Fumiaki Fujii, Shota Yoshida, Jun Nagai, Masayuki Aiba, Daisuke Hidaka, Junichi Hashiguchi, Hajime Senjo, Tetsuyuki Igarashi, Masahiro Chiba, Satoshi Yamamoto, Taku Shimizu, Takashi Ishio, Shota Yokoyama, Ko Ebata, Satoshi Iyama, Tatsuo Oyake, Takeshi Kondo, Takanori Teshima
Journal: Blood
Blood (2024) 144 (Supplement 1): 6063.
https://doi.org/10.1182/blood-2024-200013
Published: 2024
Journal Articles

Genetic Mutation and Outcome of Venetoclax-Based Therapy in Newly Diagnosed AML in the Real World: Hokkaido Leukemia Net Study

Naoki Miyashita, Masahiro Onozawa, Jun Nagai, Shota Yoshida, Hiroyuki Kimura, Toshihiro Matsukawa, Shinsuke Hirabayashi, Akio Mori, Takeshi Kondo, Daisuke Hidaka, Koichiro Minauchi, Akio Shigematsu, Junichi Hashiguchi, Tetsuyuki Igarashi, Yasutaka Kakinoki, Yutaka Tsutsumi, Hiroshi Iwasaki, Shota Yokoyama, Kentaro Wakasa, Katsuya Fujimoto, Toshimichi Ishihara, Hajime Sakai, Satoshi Iyama, Tatsuo Oyake, Takanori Teshima
Journal: Blood
Blood (2023) 142 (Supplement 1): 1470.
https://doi.org/10.1182/blood-2023-173909
Published: 2023
Journal Articles

Practical and Flexible Genome Profiling Study Using the Halo-Shape Annealing and Defer-Ligation Enrichment (HANDLE) System: HM-Screen-JAPAN02

Naoko Hosono, Takahiro Yamauchi, Chi Sung-Gi, Hironori Arai, Kentaro Fukushima, Daisuke Ikeda, Satoshi Iyama, Akihiko Gotoh, Takayuki Ikezoe, Chikashi Yoshida, Goichi Yoshimoto, Junya Kanda, Naoto Takahashi, Emiko Sakaida, Kensuke Usuki, Yosuke Minami
Journal: Blood
Blood (2023) 142 (Supplement 1): 2279.
https://doi.org/10.1182/blood-2023-184546
Published: 2023
Journal Articles

Clinical Features of Complex Karyotype in Newly Diagnosed Acute Myeloid Leukemia

Shota Yoshida, Masahiro Onozawa, Naoki Miyashita, Hiroyuki Kimura, Shogo Takahashi, Shota Yokoyama, Toshihiro Matsukawa, Shinsuke Hirabayashi, Akio Mori, Takeshi Kondo, Daisuke Hidaka, Koichiro Minauchi, Akio Shigematsu, Junichi Hashiguchi, Tetsuyuki Igarashi, Yasutaka Kakinoki, Yutaka Tsutsumi, Hiroshi Iwasaki, Hajime Kobayashi, Yoshihito Haseyama, Katsuya Fujimoto, Toshimichi Ishihara, Hajime Sakai, Satoshi Iyama, Takanori Teshima
Journal: Blood
Blood (2022) 140 (Supplement 1): 3210–3211.
https://doi.org/10.1182/blood-2022-157874
Published: 2022
Journal Articles

A Practice-Oriented Genome Profiling Study with the Novel Halo-Shape Annealing and Defer-Ligation Enrichment (HANDLE) System : HM-Screen-JAPAN02

Hironori Arai, SungGi Chi, Yoshikazu Utsu, Shinichi Masuda, Nobuyuki Aotsuka, Tomoaki Ueda, Kentaro Fukushima, Daisuke Ikeda, Naoko Hosono, Takahiro Yamauchi, Goichi Yoshimoto, Hiroto Horiguchi, Satoshi Iyama, Junya Kanda, Seiichiro Katagiri, Akihiko Gotoh, Daisuke Koyama, Takayuki Ikezoe, Takeshi Kondo, Yukinori Nakamura, Fumiya Ogasawara, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2022) 140 (Supplement 1): 10722–10724.
https://doi.org/10.1182/blood-2022-159351
Published: 2022
Journal Articles

Clinical Significance of FLT3 Mutations in a Comprehensive NGS Multicenter Study of AML: HM-Screen-Japan 01

Kentaro Fukushima, Hirohiko Shibayama, SungGi Chi, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Yoshimasa Kamoda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 2313.
https://doi.org/10.1182/blood-2021-146796
Published: 2021
Journal Articles

Genomic Analysis of NPM1 Mutation and KMT2A ( MLL )-Rearrangement/Amplification in Japanese Patients with Acute Myeloid Leukemia: Hematologic Malignancies (HM)-Screen-Japan 01

SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Yoshimasa Kamoda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Yasuyuki Nagata, Takaaki Ono, Naohito Fujishima, Naoto Takahashi, Hiroto Horiguchi, Satoshi Iyama, Makoto Nakamura, Kensuke Kojima, Kaoru Yamamoto, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4460.
https://doi.org/10.1182/blood-2021-149425
Published: 2021
Journal Articles

Properties and Distribution of IDH-1/2 Mutations in Acute Myeloid Leukemia By the Comprehensive Genomic Analysis

Satoshi Uchiyama, Nakamura Hirotaka, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4447.
https://doi.org/10.1182/blood-2021-149801
Published: 2021
Journal Articles

Genomic Analysis Focusing on RUNX1-RUNX1T1 in Japanese Patients with AML: HM-Screen-Japan 01

Seiichiro Katagiri, Daigo Akahane, Akihiko Gotoh, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Naoko Hosono, Takahiro Yamauchi, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4464.
https://doi.org/10.1182/blood-2021-148492
Published: 2021
Journal Articles

Hematologic Malignancies (HM)-Screen-Japan 01: A Mutation Profiling Multicenter Study on Patients with Acute Myeloid Leukemia

Naoko Hosono, Takahiro Yamauchi, SungGi Chi, Kentaro Fukushima, Hirohiko Shibayama, Seiichiro Katagiri, Akihiko Gotoh, Motoki Eguchi, Takanobu Morishita, Reiki Ogasawara, Takeshi Kondo, Masamitsu Yanada, Kazuhito Yamamoto, Tsutomu Kobayashi, Junya Kuroda, Kensuke Usuki, Yoshikazu Utsu, Nobuyuki Aotsuka, Makoto Yoshimitsu, Kenji Ishitsuka, Takaaki Ono, Naoto Takahashi, Satoshi Iyama, Makoto Nakamura, Yukinori Nakamura, Suguru Fukuhara, Koji Izutsu, Nobuhiko Yamauchi, Junichiro Yuda, Yosuke Minami
Journal: Blood
Blood (2021) 138 (Supplement 1): 4457.
https://doi.org/10.1182/blood-2021-149960
Published: 2021
Journal Articles

Interim Analysis of Hematologic Malignancies (HM)-Screen-Japan 01: A Mutation Profiling Multicenter Study of Patients with AML

Kenichi Miyamoto, MD, Kentaro Fukushima, MD PhD, SungGi Chi, MD PhD, Hirohiko Shibayama, MD PhD, Naoko Hosono, MD PhD, Takahiro Yamauchi, MD PhD, Seiichiro Katagiri, MDPhD, Akihiko Gotoh, MD PhD, Takanobu Morishita, MD, PhD, Masamitsu Yanada, MD PhD, Kazuhito Yamamoto, MD PhD, Naohito Fujishima, MD PhD, Naoto Takahashi, MD PhD, Reiki Ogasawara, MDPhD, Takeshi Kondo, MD PhD, Yoshikazu Utsu, MD PhD, Nobuyuki Aotsuka, MD PhD, Kensuke Usuki, MD PhD, Takaaki ONO, MD PhD, Tsutomu Kobayashi, MD PhD, Junya Kuroda, MD PhD, Hiroto Horiguchi, MDPhD, Satoshi Iyama, MD PhD, Suguru Fukuhara, MD PhD, Koji Izutsu, MD PhD, Makoto Nakamura, MD PhD, Kensuke Kojima, MD PhD, Yosuke Minami, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 2–3.
https://doi.org/10.1182/blood-2020-139147
Published: 2020
Journal Articles

Genetic Features of AML with MLL-Rearrangement and NPM1 Mutation: An Interim-Analysis of HM-Screen-Japan 01

SungGi Chi, MD PhD, Naoko Hosono, MD PhD, Takahiro Yamauchi, MD PhD, Kentaro Fukushima, MD, Hirohiko Shibayama, MD PhD, Seiichiro Katagiri, MDPhD, Akihiko Gotoh, MD PhD, Motohito Okabe, MD, Takanobu Morishita, MD, PhD, Masamitsu Yanada, MD PhD, Kazuhito Yamamoto, MD PhD, Naohito Fujishima, MD PhD, Naoto Takahashi, MD PhD, Reiki Ogasawara, MDPhD, Takeshi Kondo, MD PhD, Yoshikazu Utsu, MD PhD, Nobuyuki Aotsuka, MD, Yoshimasa Kamoda, MD, Kensuke Usuki, MD PhD, Kanenari Takemura, MD, Yasuyuki Nagata, MD PhD, Takaaki Ono, MD PhD, Tsutomu Kobayashi, MD PhD, Junya Kuroda, MD PhD, Hiroto Horiguchi, MDPhD, Satoshi Iyama, MD PhD, Suguru Fukuhara, MD PhD, Koji Izutsu, MD PhD, Makoto Nakamura, MD PhD, Kazuto Togitani, MD, Kensuke Kojima, MD PhD, Kaoru Yamamoto, MD, Yukinori Nakamura, MD, Makoto Yoshimitsu, MD PhD, Kenji Ishitsuka, MD PhD, Kenichi Miyamoto, MD, Yosuke Minami, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 35–36.
https://doi.org/10.1182/blood-2020-139240
Published: 2020
Journal Articles

Genomic Analysis of FLT3 Mutations in a Comprehensive NGS Multicenter Study of AML: HM-Screen-Japan 01

Kentaro Fukushima, MD PhD, SungGi Chi, MD PhD, Hirohiko Shibayama, MD PhD, Naoko Hosono, MD PhD, Takahiro Yamauchi, MD PhD, Seiichiro Katagiri, MDPhD, Akihiko Gotoh, MD PhD, Takanobu Morishita, MD, PhD, Masamitsu Yanada, MD PhD, Kazuhito Yamamoto, MD PhD, Naohito Fujishima, MD PhD, Naoto Takahashi, MD PhD, Reiki Ogasawara, MDPhD, Takeshi Kondo, MD PhD, Yoshikazu Utsu, MD PhD, Nobuyuki Aotsuka, MD, Kensuke Usuki, MD PhD, Takaaki ONO, MD PhD, Tsutomu Kobayashi, MD PhD, Junya Kuroda, MD PhD, Hiroto Horiguchi, MDPhD, Satoshi Iyama, MD PhD, Suguru Fukuhara, MD PhD, Koji Izutsu, MD PhD, Makoto Nakamura, MD PhD, Kensuke Kojima, MD PhD, Kenichi Miyamoto, MD, Yosuke Minami, MDPhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 32–34.
https://doi.org/10.1182/blood-2020-137343
Published: 2020
Journal Articles

CD34+ Positive Myelodysplastic Cells with Ring Sideroblasts or SF3B1 Mutation Produce High Erythroferrone and GDF15

Hiroto Horiguchi, MDPhD, Masayoshi Kobune, MD PhD, Kento Ono, MD, Saori Shimoyama, MD, Chisa Fujita, MD, Akari Goto, MDPhD, Hiroshi Ikeda, MDPhD, Satoshi Iyama, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 28–29.
https://doi.org/10.1182/blood-2020-134861
Published: 2020
Journal Articles

Prospective Evaluation of Alternative Donor from Unrelated Volunteer Donor and Cord Blood in Adult Acute Leukemia and Myelodysplastic Syndrome: No Difference between Unrelated Donor and Cord Blood

Seitaro Terakura, MD PhD, Tetsuya Nishida, MD PhD, Masashi Sawa, MD PhD, Tomonori Kato, MD PhD, Kotaro Miyao, MD PhD, Yukiyasu Ozawa, MD PhD, Tatsunori Goto, MD, Akio Kohno, MD, Kazutaka Ozeki, MD PhD, Yasushi Onishi, MD PhD, Noriko Fukuhara, MD PhD, Nobuharu Fujii, MD PhD, Hisayuki Yokoyama, MD PhD, Masanobu Kasai, MD PhD, Hiroatsu Iida, MD PhD, Nobuhiro Kanemura, MD PhD, Tomoyuki Endo, MD PhD, Hiroatsu Ago, MD, Makoto Onizuka, MD PhD, Satoshi Iyama, MD PhD, Yuichiro Nawa, MD, Mika Nakamae, MD PhD, Yasuyuki Nagata, MD PhD, Shingo Kurahashi, MD PhD, Yasuo Tomiya, MD, Atsumi Yanagisawa, Ritsuro Suzuki, MD PhD, Yachiyo Kuwatsuka, MD PhD, Yoshiko Atsuta, MD PhD, Koichi Miyamura, MD PhD, Makoto Murata, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 4587.
https://doi.org/10.1182/blood-2019-124634
Published: 2019
Journal Articles

Prospective Comparison of Azacitidine Treatment between 7-Days and 5-Days Schedules for Patients with Higher-Risk Myelodysplastic Syndromes; Results of Japan Adult Leukemia Study Group MDS212 Trial

Toru Kiguchi, MD PhD, Shinya Sato, MD, Kensuke Usuki, MD PhD, Ken Ishiyama, Yoshikazu Ito, MD PhD, Takahiro Suzuki, MD PhD, Jun Taguchi, MD PhD, Shigeru Chiba, MD PhD, Nobuaki Dobashi, MD, Akihiro Tomita, MD PhD, Hironori Harada, MD PhD, Hiroshi Handa, MD PhD, Shigeo Horiike, MD PhD, Tomoya Maeda, MD PhD, Mitsuhiro Matsuda, MD PhD, Motoshi Ichikawa, MD, Tomoko Hata, MD, PhD, Sumihisa Honda, Satoshi Iyama, MD PhD, Hitoshi Suzushima, MD PhD, Yukiyoshi Moriuchi, MD, Toshiro Kurokawa, MD PhD, Takahiro Yamauchi, MD PhD, Hitoshi Kiyoi, MD PhD, Tomoki Naoe, MD PhD, Yasushi Miyazaki, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 845.
https://doi.org/10.1182/blood-2019-122802
Published: 2019
Journal Articles

Extravesicular Mir-7977 Released from Leukemic Cells Inhibites the PCBP1-Mediated mRNA Stabilization and Hippo-YAP Signaling Pathway in Bone Marrow Mesenchymal Stromal Cells

Masahiro Yoshida, MD PhD, Satoshi Iyama, MD PhD, Hiroto Horiguchi, MD PhD, Akari Goto, MD PhD, Shohei Kikuchi, MD PhD, Kazuyuki Murase, MD PhD, Kohichi Takada, MD PhD, Koji Miyanishi, MD PhD, Hiroshi Ikeda, MD PhD, Masahiro Maeda, MD PhD, Junji Kato, MD PhD, Masayoshi Kobune, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1519.
https://doi.org/10.1182/blood-2018-99-111124
Published: 2018
Journal Articles

Extracellular Vesicle microRNAs from Acute Myeloid Leukemia Are Involved in the Regulation of Adherence Junction in Bone Marrow Microenvironment.

Masahiro Yoshida, MD, Masayoshi Kobune, MD PhD, Shogo Miura, MD, Soushi Ibata, MD PhD, Satoshi Iyama, MD PhD, Tsutomu Sato, MD PhD, Kazuyuki Murase, MD PhD, Kohichi Takada, MD PhD, Kaoru Ono, MD PhD, Akari Hashimoto, MD, Ayumi Tatekoshi, MD, Yusuke Kamihara, MD PhD, Yusuke Sugama, MD, Shohei Kikuchi, MD PhD, Hiroshi Ikeda, MD PhD, Hiroto Horiguchi, MD PhD, Yutaka Kawano, MD PhD, Koji Miyanishi, MD PhD, Hiroyuki Kuroda, MD PhD, Masahiro Maeda, MD PhD, Junji Kato, MD PhD
Journal: Blood
Blood (2016) 128 (22): 2863.
https://doi.org/10.1182/blood.V128.22.2863.2863
Published: 2016
Journal Articles

Next Generation Sequencing of CD138+ Myeloma Cells Could Predict Response Rate and Appropriate Therapy at Diagnosis

Hiroshi Ikeda, MD PhD, Yasushi Sasaki, MDPhD, Soushi Ibata, MD PhD, Masahiro Yoshida, MD, Ayumi Tatekoshi, Satoshi Iyama, MD PhD, Kazuyuki Murase, MD PhD, Kohichi Takada, MD PhD, Shohei Kikuchi, MD PhD, Tsutomu Sato, MD PhD, Masayoshi Kobune, MD PhD, Junji Kato, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5609.
https://doi.org/10.1182/blood.V128.22.5609.5609
Published: 2016