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Journal Articles

Monotherapy update from Phase 1 portion in Phase1/2 trial of the menin-MLL inhibitor enzomenib (DSP-5336) in patients with relapsed or refractory acute leukemia

Blood (2025) 146 (Supplement 1): 763.

https://doi.org/10.1182/blood-2025-763

Published: 2025

Journal Articles

Cell intrinsic heme synthesis supports glycolysis for activation of naive CD4+ T cell

Kazuki Sakurai, Hiroki Kato, Yan Yan, Sayaka Sano, Daigo Michimata, Kazuki Hashimoto, Naoya Morota, Hiroka Komatsu, Tatsuya Watanabe, Daichi Kiba, Yuya Tanaka, Koichi Onodera, Shunsuke Hatta, Yasushi Onishi, Toru Fujiwara, Noriko Fukuhara, Hideo Harigae

Blood (2025) 146 (Supplement 1): 627.

https://doi.org/10.1182/blood-2025-627

Published: 2025

Journal Articles

Efficacy and safety of talquetamab + teclistamab in patients with Relapsed/Refractory multiple myeloma and extramedullary disease: Updated Phase 2 results from the redirectt-1 study with extended follow-up

Blood (2025) 146 (Supplement 1): 698.

https://doi.org/10.1182/blood-2025-698

Published: 2025

Journal Articles

Phase 1 Results: First-in-Human Phase 1/2 Study of the Menin-MLL Inhibitor Enzomenib (DSP-5336) in Patients with Relapsed or Refractory Acute Leukemia

Blood (2024) 144 (Supplement 1): 213.

https://doi.org/10.1182/blood-2024-194827

Published: 2024

Journal Articles

RNA Methyltransferase Mettl16 Is Indispensable for the Survival of Naïve CD4 + T Cells In Vivo

Daigo Michimata, Hiroki Kato, Naoya Morota, Yuya Tanaka, Kazuki Sakurai, Kazuki Hashimoto, Koichi Onodera, Shunsuke Hatta, Yasushi Onishi, Noriko Fukuhara, Hideo Harigae

Blood (2024) 144 (Supplement 1): 2534.

https://doi.org/10.1182/blood-2024-198338

Published: 2024

Journal Articles

Transcription Factor Gata2 Regulates the Myeloid-Lymphoid Fate Decision in Multipotent Progenitors

Yuya Tanaka, Hiroki Kato, Sayaka Sano, Daigo Michimata, Kazuki Sakurai, Kazuki Hashimoto, Naoya Morota, Koichi Onodera, Shunsuke Hatta, Noriko Fukuhara, Yasushi Onishi, Tohru Fujiwara, Hideo Harigae

Blood (2024) 144 (Supplement 1): 4037.

https://doi.org/10.1182/blood-2024-207236

Published: 2024

Journal Articles

AML-Mrg Mutation Spectrum and Its Prognosis: A Japanese Multicenter Study HM01-02 Analysis with Full Analysis Sets

Blood (2024) 144 (Supplement 1): 6123.

https://doi.org/10.1182/blood-2024-202327

Published: 2024

Journal Articles

Transcription Factor GATA2 Is Inevitable for the Survival and Proper Differentiation of Thymic Multipotent Progenitor Cells By Gene Expression Orchestration

Sayaka Sano, Hiroki Kato, Yan Yan, Eijiro Furukawa, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Tohru Fujiwara, Hideo Harigae

Blood (2023) 142 (Supplement 1): 1182.

https://doi.org/10.1182/blood-2023-178454

Published: 2023

Journal Articles

HLA Class I Genotypes Predict the Survival after Hematopoietic Stem Cell Transplantation in Immune Aplastic Anemia

Yoshitaka Zaimoku, Hirohito Yamazaki, Minoru Kanaya, Nobuhiro Hiramoto, Ken Ishiyama, Naoyuki Uchida, Noriko Doki, Ryusuke Yamamoto, Tetsuya Nishida, Koichi Onodera, Shinichiro Machida, Yoshinobu Kanda, Tetsuya Eto, Fumihiko Ishimaru, Makoto Onizuka, Tatsuo Ichinohe, Yoshiko Atsuta, Yasushi Onishi

Blood (2023) 142 (Supplement 1): 706.

https://doi.org/10.1182/blood-2023-191332

Published: 2023

Journal Articles

Recurrence of HBV Reactivation after Allogeneic Hematopoietic Transplantation in Recipients with Resolved HBV Infection: A Nation-Wide Multicenter Retrospective Study

Masahiro Onozawa, Shigeru Kusumoto, Yuho Najima, Hiroya Hashimoto, Kohei Okada, Masaharu Tamaki, Masatsugu Tanaka, Takayuki Sato, Tsutomu Takahashi, Kaoru Hatano, Koichi Onodera, Yukiyoshi Moriuchi, Kimikazu Yakushijin, Junya Kanda, Koji Nagafuji, Masao Ogata, Nobuaki Nakano, Akihiro Tamori, Masashi Mizokami

Blood (2023) 142 (Supplement 1): 3541.

https://doi.org/10.1182/blood-2023-173461

Published: 2023

Journal Articles

Hematopoietic Stem/Progenitor Cell Intrinsic SAM Synthesis Is Required to Prevent p53 Pathway Activation By Maintaining DNA Stability

Eijiro Furukawa, Hiroki Kato, Sayaka Sano, Yan Yan, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Daisuke Saigusa, Tohru Fujiwara, Kazuhiko Igarashi, Hideo Harigae

Blood (2023) 142 (Supplement 1): 4049.

https://doi.org/10.1182/blood-2023-180384

Published: 2023

Journal Articles

Roles for Heme Synthesis in the Maintenance of Hematopoietic Stem and Progenitor Cells

Yan Yan, Hiroki Kato, Sayaka Sano, Eijiro Furukawa, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Tohru Fujiwara, Yasushi Onishi, Noriko Fukuhara, Hisayuki Yokoyama, Hideo Harigae

Blood (2023) 142 (Supplement 1): 2682.

https://doi.org/10.1182/blood-2023-174202

Published: 2023

Journal Articles

Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia

Koya Ono, Tohru Fujiwara, Hiroki Shima, Hironari Nishizawa, Chie Suzuki, Noriyuki Takahashi, Hiroki Kato, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Kazuhiko Igarashi, Hideo Harigae

Blood (2022) 140 (Supplement 1): 2467–2468.

https://doi.org/10.1182/blood-2022-163073

Published: 2022

Journal Articles

Long-Term Hemoglobin Response and Reduction in Transfusion Burden Are Maintained in Patients with Pyruvate Kinase Deficiency Treated with Mitapivat

Blood (2022) 140 (Supplement 1): 5313–5315.

https://doi.org/10.1182/blood-2022-169125

Published: 2022

Journal Articles

Durability of Hemoglobin Response and Reduction in Transfusion Burden Is Maintained over Time in Patients with Pyruvate Kinase Deficiency Treated with Mitapivat in a Long-Term Extension Study

Blood (2021) 138 (Supplement 1): 848.

https://doi.org/10.1182/blood-2021-147711

Published: 2021

Journal Articles

Molecular Characterization and Novel Therapeutic Strategy for X-Linked Sideroblastic Anemia Associated with ALAS2 Missense Variants

Koya Ono, MD, Tohru Fujiwara, MD PhD, Kei Saito, MD PhD, Chie Suzuki, Noriyuki Takahashi, Koichi Onodera, MD PhD, Satoshi Ichikawa, MD PhD, Noriko Fukuhara, MD PhD, Yasushi Onishi, MD PhD, Hisayuki Yokoyama, MD PhD, Yukio Nakamura, MD PhD, Hideo Harigae, MD PhD

Blood (2019) 134 (Supplement_1): 3530.

https://doi.org/10.1182/blood-2019-124810

Published: 2019

Journal Articles

GATA2 regulates dendritic cell differentiation

Koichi Onodera, Tohru Fujiwara, Yasushi Onishi, Ari Itoh-Nakadai, Yoko Okitsu, Noriko Fukuhara, Kenichi Ishizawa, Ritsuko Shimizu, Masayuki Yamamoto, Hideo Harigae

Blood (2016) 128 (4): 508–518.

https://doi.org/10.1182/blood-2016-02-698118

Published: 2016

Includes: Supplemental data

Journal Articles

GATA-2 Regulates Dendritic Cell Differentiation

Koichi Onodera, MD, PhD, Tohru Fujiwara, MD, PhD, Yasushi Onishi, MD, PhD, Ari Itoh-Nakadai, PhD, Yoko Okitsu, MD PhD, Noriko Fukuhara, MD PhD, Kenichi Ishizawa, MD, PhD, Ritsuko Shimizu, MD, PhD, Masayuki Yamamoto, MD, PhD, Hideo Harigae, MD, PhD

Blood (2015) 126 (23): 2382.

https://doi.org/10.1182/blood.V126.23.2382.2382

Published: 2015

Journal Articles

Iron Overload In Adult Allogeneic Hematopoietic Stem Cell Transplantation Survivors: Quantification of Iron Burden by Determining Non-Transferrin-Bound Iron.

Tatsunori Goto, MD, Katsuya Ikuta, MD, PhD, Emi Yokohata, MD, Daisuke Koyama, MD, Koichi Onodera, MD, Aika Seto, MD, Keisuke Watanabe, Yukiyasu Ozawa, MD, PhD, Katsunori Sasaki, PhD, Yutaka Kohgo, MD, PhD, Koichi Miyamura, MD, PhD

Blood (2010) 116 (21): 3455.

https://doi.org/10.1182/blood.V116.21.3455.3455

Published: 2010

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Monotherapy update from Phase 1 portion in Phase1/2 trial of the menin-MLL inhibitor enzomenib (DSP-5336) in patients with relapsed or refractory acute leukemia

Cell intrinsic heme synthesis supports glycolysis for activation of naive CD4+ T cell

Efficacy and safety of talquetamab + teclistamab in patients with Relapsed/Refractory multiple myeloma and extramedullary disease: Updated Phase 2 results from the redirectt-1 study with extended follow-up

Phase 1 Results: First-in-Human Phase 1/2 Study of the Menin-MLL Inhibitor Enzomenib (DSP-5336) in Patients with Relapsed or Refractory Acute Leukemia

RNA Methyltransferase Mettl16 Is Indispensable for the Survival of Naïve CD4 + T Cells In Vivo

Transcription Factor Gata2 Regulates the Myeloid-Lymphoid Fate Decision in Multipotent Progenitors

AML-Mrg Mutation Spectrum and Its Prognosis: A Japanese Multicenter Study HM01-02 Analysis with Full Analysis Sets

Transcription Factor GATA2 Is Inevitable for the Survival and Proper Differentiation of Thymic Multipotent Progenitor Cells By Gene Expression Orchestration

HLA Class I Genotypes Predict the Survival after Hematopoietic Stem Cell Transplantation in Immune Aplastic Anemia

Recurrence of HBV Reactivation after Allogeneic Hematopoietic Transplantation in Recipients with Resolved HBV Infection: A Nation-Wide Multicenter Retrospective Study

Hematopoietic Stem/Progenitor Cell Intrinsic SAM Synthesis Is Required to Prevent p53 Pathway Activation By Maintaining DNA Stability

Roles for Heme Synthesis in the Maintenance of Hematopoietic Stem and Progenitor Cells

Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia

Long-Term Hemoglobin Response and Reduction in Transfusion Burden Are Maintained in Patients with Pyruvate Kinase Deficiency Treated with Mitapivat

Durability of Hemoglobin Response and Reduction in Transfusion Burden Is Maintained over Time in Patients with Pyruvate Kinase Deficiency Treated with Mitapivat in a Long-Term Extension Study

Molecular Characterization and Novel Therapeutic Strategy for X-Linked Sideroblastic Anemia Associated with ALAS2 Missense Variants

GATA2 regulates dendritic cell differentiation

GATA-2 Regulates Dendritic Cell Differentiation

Iron Overload In Adult Allogeneic Hematopoietic Stem Cell Transplantation Survivors: Quantification of Iron Burden by Determining Non-Transferrin-Bound Iron.

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