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Journal Articles

Hematopoietic Stem/Progenitor Cell Intrinsic SAM Synthesis Is Required to Prevent p53 Pathway Activation By Maintaining DNA Stability

Eijiro Furukawa, Hiroki Kato, Sayaka Sano, Yan Yan, Daigo Michimata, Yuya Tanaka, Kazuki Sakurai, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Daisuke Saigusa, Tohru Fujiwara, Kazuhiko Igarashi, Hideo Harigae

Blood (2023) 142 (Supplement 1): 4049.

https://doi.org/10.1182/blood-2023-180384

Published: 2023

Journal Articles

Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia

Koya Ono, Tohru Fujiwara, Hiroki Shima, Hironari Nishizawa, Chie Suzuki, Noriyuki Takahashi, Hiroki Kato, Koichi Onodera, Satoshi Ichikawa, Noriko Fukuhara, Yasushi Onishi, Hisayuki Yokoyama, Yukio Nakamura, Kazuhiko Igarashi, Hideo Harigae

Blood (2022) 140 (Supplement 1): 2467–2468.

https://doi.org/10.1182/blood-2022-163073

Published: 2022

Journal Articles

Inhibition of S-Adenosylmethionine Synthesis Promotes Erythropoiesis Via Epigenetic Modifications

Hiroki Kato, Nguyen Chi Long, Yusho Ishii, Mitsuyo Matsumoto, Catherine Rhee, Daisuke Saigusa, Ryo Funayama, Hiroaki Okae, Tohru Fujiwara, Akihiko Muto, Hideo Harigae, David T. Scadden, Kazuhiko Igarashi

Blood (2021) 138 (Supplement 1): 1991.

https://doi.org/10.1182/blood-2021-147065

Published: 2021

Journal Articles

Transcription Factor Bach1 and Bach2 Operate Erythro-Myeloid Competitive Differentiation By Responding to Environmental Changes

Hiroki Kato, MD, Ari Itoh-Nakadai, PhD, Mitsuyo Matsumoto, PhD, Risa Ebina-Shibuya, MD PhD, Yuki Sato, MD, Masahiro Kobayashi, MD PhD, Akihiko Muto, PhD, Tohru Fujiwara, MD PhD, Hideo Harigae, MD PhD, Kazuhiko Igarashi, MD PhD

Blood (2016) 128 (22): 2649.

https://doi.org/10.1182/blood.V128.22.2649.2649

Published: 2016

Journal Articles

Transcription Factor Bach1 and Bach2 Control Common Myeloid Progenitor Cell Differentiation Under Infectious Stimuli

Hiroki Kato, MD, Ari Itoh-Nakadai, PhD, Risa Ebina-Shibuya, MD, Masahiro Kobayashi, MD PhD, Mitsuyo Matsumoto, PhD, Akihiko Muto, PhD, Tohru Fujiwara, MD PhD, Hideo Harigae, MD PhD, Kazuhiko Igarashi, MD PhD

Blood (2015) 126 (23): 1164.

https://doi.org/10.1182/blood.V126.23.1164.1164

Published: 2015

Journal Articles

Mechanism Governing Heme Synthesis Reveals a GATA Factor-Heme Circuit That Controls Differentiation

Emery H Bresnick, PhD, Nobuyuki Tanimura, Eli Miller, Kazuhiko Igarashi, MD PhD, David T Yang, MD, Judith Burstyn, Colin Dewey

Blood (2015) 126 (23): 161.

https://doi.org/10.1182/blood.V126.23.161.161

Published: 2015

Journal Articles

BACH2 promotes Lineage-Specific Fate Decisions in BCR-ABL1 -Driven Leukemia

Eugene Park, Srividya Swaminathan, PhD, Mohammed Firas Sadiyah, PhD, Kazuhiko Igarashi, PhD, Ari Melnick, MD, Markus Muschen, MDPhD

Blood (2014) 124 (21): 513.

https://doi.org/10.1182/blood.V124.21.513.513

Published: 2014

Journal Articles

BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance

Srividya Swaminathan, B Tech, Huining Kang, PhD, Richard C. Harvey, PhD, Chuanxin Huang, PhD, Maike Buchner, PhD, Zhengshan Chen, MD, PhD, Huimin Geng, Andrew Hall, Kazuhiko Igarashi, PhD, William L. Carroll, MD, Cheryl L. Willman, MD, Ari Melnick, MD, Markus Muschen, MD, PhD

Blood (2012) 120 (21): 1300.

https://doi.org/10.1182/blood.V120.21.1300.1300

Published: 2012

Journal Articles

BACH2 Mediates Early B Cell Differentiation and Oncogene-Induced Senescence in Acute Lymphoblastic Leukemia

Srividya Swaminathan, Chuanxin Huang, PhD, Bjorn Titz, PhD, Maike Buchner, Huimin Geng, PhD, Thomas G Graeber, PhD, Cheryl L Willman, MD, Kazuhiko Igarashi, MD, PhD, Ari Melnick, MD, Markus Muschen

Blood (2011) 118 (21): 562.

https://doi.org/10.1182/blood.V118.21.562.562

Published: 2011

Journal Articles

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

Miki Watanabe-Matsui, Akihiko Muto, Toshitaka Matsui, Ari Itoh-Nakadai, Osamu Nakajima, Kazutaka Murayama, Masayuki Yamamoto, Masao Ikeda-Saito, Kazuhiko Igarashi

Blood (2011) 117 (20): 5438–5448.

https://doi.org/10.1182/blood-2010-07-296483

Published: 2011

Journal Articles

Identification of a Novel Acetyl-CoA Binding Protein (EST1) Which Epigenetically Regulates the Expression of Erythroid-Specific Genes

Tohru Fujiwara, M.D./Ph.D., Tsuyoshi Ikura, Ph.D, Satoshi Ichikawa, M.D., Shinichiro Takahashi, MD, PhD, Kazumichi Furuyama, M.D., Kazuhiko Igarashi, M.D., Hideo Harigae, M.D.

Blood (2008) 112 (11): 4761.

https://doi.org/10.1182/blood.V112.11.4761.4761

Published: 2008

Journal Articles

Analyses of Heme-Regulated Genes during Erythoid Differentiation.

Tohru Fujiwara, Yoko Okitsu, Tsuyoshi Ikura, Shinichiro Takahashi, Kazumichi Furuyama, Kazuhiko Igarashi, Masayuki Yamamoto, Shigeru Sassa, Hideo Harigae

Blood (2007) 110 (11): 2660.

https://doi.org/10.1182/blood.V110.11.2660.2660

Published: 2007

Journal Articles

Bcr-Abl signaling through the PI-3/S6 kinase pathway inhibits nuclear translocation of the transcription factor Bach2, which represses the antiapoptotic factor heme oxygenase-1

Chikashi Yoshida, Fumiko Yoshida, Daniel E. Sears, Stephen M. Hart, Dai Ikebe, Akihiko Muto, Subham Basu, Kazuhiko Igarashi, Junia V. Melo

Blood (2006) 109 (3): 1211–1219.

https://doi.org/10.1182/blood-2005-12-040972

Published: 2006

Includes: Supplemental data

Journal Articles

Transcriptional Regulation of the Bach2 B-Cell Differentiation and Apoptotic Factor by the Bcr-Abl Oncoprotein.

Maria Makri, BSc, Chikashi Yoshida, MD, PhD, Akihiko Muto, PhD, Kazuhiko Igarashi, MD, PhD, Junia V Melo, MD, PhD

Blood (2005) 106 (11): 2991.

https://doi.org/10.1182/blood.V106.11.2991.2991

Published: 2005

Journal Articles

Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment

Tsutomu Toki, Fumiki Katsuoka, Rika Kanezaki, Gang Xu, Hidekachi Kurotaki, Jiying Sun, Takuya Kamio, Seiji Watanabe, Satoru Tandai, Kiminori Terui, Soroku Yagihashi, Norio Komatsu, Kazuhiko Igarashi, Masayuki Yamamoto, Etsuro Ito

Blood (2005) 105 (8): 3100–3108.

https://doi.org/10.1182/blood-2004-07-2826

Published: 2005

Journal Articles

Transgenic Expression of Bach1 Transcription Factor Results in Down-Regulation of the p45 Target Genes in Megakaryocytic Lineage Cells.

Tsutomu Toki, PhD, Fumiki Katsuoka, MD, Rika Kanezaki, MS, Seiji Watanabe, PhD, Takuya Kamio, MD, Satoru Tandai, MD, Hidekachi Kurotaki, MD, Soroku Yagihashi, MD, Jiying Sun, PhD, Norio Komatsu, MD, PhD, Kazuhiko Igarashi, MD, PhD, Masayuki Yamamoto, MD, PhD, Etsuro Ito, MD, PhD

Blood (2004) 104 (11): 1605.

https://doi.org/10.1182/blood.V104.11.1605.1605

Published: 2004

Journal Articles

B-cell–specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs

Takuya Kamio, Tsutomu Toki, Rika Kanezaki, Shinya Sasaki, Satoru Tandai, Kiminori Terui, Dai Ikebe, Kazuhiko Igarashi, Etsuro Ito

Blood (2003) 102 (9): 3317–3322.

https://doi.org/10.1182/blood-2002-12-3656

Published: 2003

NARROW

Hematopoietic Stem/Progenitor Cell Intrinsic SAM Synthesis Is Required to Prevent p53 Pathway Activation By Maintaining DNA Stability

Altered Transcription By GATA1 Impairs Autophagy and Prevents Ferroptosis in X-Linked Sideroblastic Anemia

Inhibition of S-Adenosylmethionine Synthesis Promotes Erythropoiesis Via Epigenetic Modifications

Transcription Factor Bach1 and Bach2 Operate Erythro-Myeloid Competitive Differentiation By Responding to Environmental Changes

Transcription Factor Bach1 and Bach2 Control Common Myeloid Progenitor Cell Differentiation Under Infectious Stimuli

Mechanism Governing Heme Synthesis Reveals a GATA Factor-Heme Circuit That Controls Differentiation

BACH2 promotes Lineage-Specific Fate Decisions in BCR-ABL1 -Driven Leukemia

BACH2 Is Required for Pre-B Cell Receptor Checkpoint Control and p53-Dependent Tumor Surveillance

BACH2 Mediates Early B Cell Differentiation and Oncogene-Induced Senescence in Acute Lymphoblastic Leukemia

Heme regulates B-cell differentiation, antibody class switch, and heme oxygenase-1 expression in B cells as a ligand of Bach2

Identification of a Novel Acetyl-CoA Binding Protein (EST1) Which Epigenetically Regulates the Expression of Erythroid-Specific Genes

Analyses of Heme-Regulated Genes during Erythoid Differentiation.

Bcr-Abl signaling through the PI-3/S6 kinase pathway inhibits nuclear translocation of the transcription factor Bach2, which represses the antiapoptotic factor heme oxygenase-1

Transcriptional Regulation of the Bach2 B-Cell Differentiation and Apoptotic Factor by the Bcr-Abl Oncoprotein.

Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment

Transgenic Expression of Bach1 Transcription Factor Results in Down-Regulation of the p45 Target Genes in Megakaryocytic Lineage Cells.

B-cell–specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs

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American Society of Hematology

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ASH Publications

American Society of Hematology

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