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Journal Articles

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance

Karl Agger, Koutarou Nishimura, Satoru Miyagi, Jan-Erik Messling, Kasper Dindler Rasmussen, Kristian Helin

Blood (2019) 134 (14): 1154–1158.

https://doi.org/10.1182/blood.2019000855

Published: 2019

Includes: Supplemental data

Journal Articles

The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells

Satoru Miyagi, Patrycja Sroczynska, Yuko Kato, Yaeko Nakajima-Takagi, Motohiko Oshima, Ola Rizq, Naoya Takayama, Atsunori Saraya, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Yumi Matsuzaki, Jesper Christensen, Kristian Helin, Atsushi Iwama

Blood (2019) 133 (23): 2495–2506.

https://doi.org/10.1182/blood.2019000468

Published: 2019

Includes: Supplemental data

Journal Articles

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

Shiro Tara, Yusuke Isshiki, Yaeko Nakajima-Takagi, Motohiko Oshima, Kazumasa Aoyama, Tomoyuki Tanaka, Daisuke Shinoda, Shuhei Koide, Atsunori Saraya, Satoru Miyagi, Ichiro Manabe, Hirotaka Matsui, Haruhiko Koseki, Vivian J. Bardwell, Atsushi Iwama

Blood (2018) 132 (23): 2470–2483.

https://doi.org/10.1182/blood-2018-01-827964

Published: 2018

Includes: Supplemental data

Journal Articles

Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes

Shuhei Koide, Motohiko Oshima, Keiyo Takubo, Satoshi Yamazaki, Eriko Nitta, Atsunori Saraya, Kazumasa Aoyama, Yuko Kato, Satoru Miyagi, Yaeko Nakajima-Takagi, Tetsuhiro Chiba, Hirotaka Matsui, Fumio Arai, Yutaka Suzuki, Hiroshi Kimura, Hiromitsu Nakauchi, Toshio Suda, Yoichi Shinkai, Atsushi Iwama

Blood (2016) 128 (5): 638–649.

https://doi.org/10.1182/blood-2016-01-694810

Published: 2016

Includes: Supplemental data

Journal Articles

Epigenetic Regulation of Hematopoietic Stem and Progenitor Cells By the Eset Histone Methyltranferas

Shuhei Koide, Keiyo Takubo, MD PhD, Motohiko Oshima, PhD, Satoru Miyagi, PhD, Hirotaka Matsui, MD PhD, Hiroshi Kimura, PhD, Changshan Wang, PhD, George R Wendt, Shogo Yabata, Yoichi Shinkai, MD PhD, Toshio Suda, MD PhD, Atsushi Iwama, MD PhD

Blood (2014) 124 (21): 765.

https://doi.org/10.1182/blood.V124.21.765.765

Published: 2014

Journal Articles

Ezh2 Is Required for Developmental Stage-Specific Silencing of Oncofetal Genes in Hematopoietic Stem/Progenitor Cells

Motohiko Oshima, PhD, Satoru Miyagi, PhD, Shuhei Koide, George Russel Wendt, BS, Nagisa Hasegawa, MD, Shogo Yabata, Changshan Wang, PhD, Yutaka Suzuki, PhD, Atsushi Iwama, MD PhD

Blood (2014) 124 (21): 2900.

https://doi.org/10.1182/blood.V124.21.2900.2900

Published: 2014

Journal Articles

Histone Acetylation Mediated by Brd1 Is Crucial for Cd8 Gene Activation during Early Thymocyte Development

Yuta Mishima, PhD, Changshan Wang, PhD, Satoru Miyagi, PhD, Atsunori Saraya, MS, Hiroyuki Hosokawa, PhD, Naoto Yamaguchi, PhD, Toshinori Nakayama, MD PhD, Haruhiko Koseki, MD PhD, Ichiro Taniuchi, MD PhD, Atsushi Iwama, MD PhD

Blood (2014) 124 (21): 1576.

https://doi.org/10.1182/blood.V124.21.1576.1576

Published: 2014

Journal Articles

shRNA screening identifies JMJD1C as being required for leukemia maintenance

Patrycja Sroczynska, V. Adam Cruickshank, John-Paul Bukowski, Satoru Miyagi, Frederik Otzen Bagger, Julian Walfridsson, Mikkel Bruhn Schuster, Bo Porse, Kristian Helin

Blood (2014) 123 (12): 1870–1882.

https://doi.org/10.1182/blood-2013-08-522094

Published: 2014

Includes: Supplemental data

Journal Articles

Concurrent Loss Of Ezh2 and Tet2 Cooperates In The Pathogenesis Of Myelodysplastic Disorders,

Tomoya Muto, MD, PhD, Goro Sashida, MD, PhD, Motohiko Oshima, PhD, George R Wendt, Makiko Mochizuki-Kashio, PhD, Masashi Sanada, MD, Satoru Miyagi, PhD., Atsunori Saraya, MS, Chiaki Nakaseko, M.D., Ph.D., Koutaro Yokote, MD, PhD, Kazuya Shimoda, MD, PhD, Haruhiko Koseki, MD, PhD, Yutaka Suzuki, PhD, Sumio Sugano, PhD, Seishi Ogawa, MD, PhD, Atsushi Iwama, MD, PhD

Blood (2013) 122 (21): 480.

https://doi.org/10.1182/blood.V122.21.480.480

Published: 2013

Journal Articles

Role of SOX17 in hematopoietic development from human embryonic stem cells

Yaeko Nakajima-Takagi, Mitsujiro Osawa, Motohiko Oshima, Haruna Takagi, Satoru Miyagi, Mitsuhiro Endoh, Takaho A. Endo, Naoya Takayama, Koji Eto, Tetsuro Toyoda, Haruhiko Koseki, Hiromitsu Nakauchi, Atsushi Iwama

Blood (2013) 121 (3): 447–458.

https://doi.org/10.1182/blood-2012-05-431403

Published: 2013

Includes: Supplemental data

Journal Articles

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia

Satomi Tanaka, Satoru Miyagi, Goro Sashida, Tetsuhiro Chiba, Jin Yuan, Makiko Mochizuki-Kashio, Yutaka Suzuki, Sumio Sugano, Chiaki Nakaseko, Koutaro Yokote, Haruhiko Koseki, Atsushi Iwama

Blood (2012) 120 (5): 1107–1117.

https://doi.org/10.1182/blood-2011-11-394932

Published: 2012

Includes: Supplemental data

Journal Articles

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells

Makiko Mochizuki-Kashio, Yuta Mishima, Satoru Miyagi, Masamitsu Negishi, Atsunori Saraya, Takaaki Konuma, Jun Shinga, Haruhiko Koseki, Atsushi Iwama

Blood (2011) 118 (25): 6553–6561.

https://doi.org/10.1182/blood-2011-03-340554

Published: 2011

Includes: Supplemental data

Journal Articles

Ezh2 Plays a Critical Role in the Progression of MLL-AF9 -Induced Acute Myeloid Leukemia

Satomi Tanaka, MD, Goro Sashida, MD, Satoru Miyagi, PhD., Koutaro Yokote, MD, PhD, Chiaki Nakaseko, MD, PhD, Atsushi Iwama, M.D., PhD.

Blood (2011) 118 (21): 57.

https://doi.org/10.1182/blood.V118.21.57.57

Published: 2011

Journal Articles

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

Yuta Mishima, Satoru Miyagi, Atsunori Saraya, Masamitsu Negishi, Mitsuhiro Endoh, Takaho A. Endo, Tetsuro Toyoda, Jun Shinga, Takuo Katsumoto, Tetsuhiro Chiba, Naoto Yamaguchi, Issay Kitabayashi, Haruhiko Koseki, Atsushi Iwama

Blood (2011) 118 (9): 2443–2453.

https://doi.org/10.1182/blood-2011-01-331892

Published: 2011

Includes: Supplemental data

Journal Articles

The Hbo1-Brd1/Brpf2 HAT Complex Is Required for Erythropoiesis In Fetal Liver

Yuta Mishima, Satoru Miyagi, Atsunori Saraya, Masamitsu Negishi, Mitsuhiro Endoh, Naoto Yamaguchi, Issay Kitabayashi, Haruhiko Koseki, Atsushi Iwama

Blood (2010) 116 (21): 3872.

https://doi.org/10.1182/blood.V116.21.3872.3872

Published: 2010

Journal Articles

Direct Activation of STAT5 by TEL-Lyn Fusion Protein Promotes Induction of Myeloproliferative Neoplasms with Myelofibrosis

Yusuke Takeda, M.D., PhD., Chiaki Nakaseko, M.D., PhD., Hiroaki Tanaka, M.D., PhD., Masahiro Takeuchi, M.D., PhD., Makiko Yui, Atsunori Saraya, Satoru Miyagi, PhD., Chikako Ohwada, M.D., PhD., Emiko Sakaida, M.D., PhD., Koutaro Yokote, M.D., PhD., Atsushi Iwama, M.D., PhD.

Blood (2010) 116 (21): 4114.

https://doi.org/10.1182/blood.V116.21.4114.4114

Published: 2010

Journal Articles

Identification of a Novel TEL-Lyn Fusion Gene in Chronic Eosinophilic Leukemia with ins (12;8)(p13;q11q21): Effect on Myeloproliferative Transformation and Induction of Myelofibrosis.

Hiroaki Tanaka, MD, Masahiro Takeuchi, MD, Yusuke Takeda, MD, Kayo Oda, MD, Daijiro Abe, MD, Chikako Ohwada, MD, PhD, Shinichi Ozawa, MD, PhD, Emiko Sakaida, MD, PhD, Naomi Shimizu, MD, PhD, Ryuko Cho, MD, PhD, Miki Nishimura, MD, PhD, Yasushi Saito, MD, PhD, Satoru Miyagi, PhD, Atsushi Iwama, MD, PhD, Chiaki Nakaseko, MD, PhD

Blood (2007) 110 (11): 60.

https://doi.org/10.1182/blood.V110.11.60.60

Published: 2007

NARROW

The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance

The chromatin-binding protein Phf6 restricts the self-renewal of hematopoietic stem cells

Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome

Setdb1 maintains hematopoietic stem and progenitor cells by restricting the ectopic activation of nonhematopoietic genes

Epigenetic Regulation of Hematopoietic Stem and Progenitor Cells By the Eset Histone Methyltranferas

Ezh2 Is Required for Developmental Stage-Specific Silencing of Oncofetal Genes in Hematopoietic Stem/Progenitor Cells

Histone Acetylation Mediated by Brd1 Is Crucial for Cd8 Gene Activation during Early Thymocyte Development

shRNA screening identifies JMJD1C as being required for leukemia maintenance

Concurrent Loss Of Ezh2 and Tet2 Cooperates In The Pathogenesis Of Myelodysplastic Disorders,

Role of SOX17 in hematopoietic development from human embryonic stem cells

Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia

Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic stem cells

Ezh2 Plays a Critical Role in the Progression of MLL-AF9 -Induced Acute Myeloid Leukemia

The Hbo1-Brd1/Brpf2 complex is responsible for global acetylation of H3K14 and required for fetal liver erythropoiesis

The Hbo1-Brd1/Brpf2 HAT Complex Is Required for Erythropoiesis In Fetal Liver

Direct Activation of STAT5 by TEL-Lyn Fusion Protein Promotes Induction of Myeloproliferative Neoplasms with Myelofibrosis

Identification of a Novel TEL-Lyn Fusion Gene in Chronic Eosinophilic Leukemia with ins (12;8)(p13;q11q21): Effect on Myeloproliferative Transformation and Induction of Myelofibrosis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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