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Journal Articles

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Blood (2021) 137 (7): 908–922.

https://doi.org/10.1182/blood.2019001044

Published: 2021

Includes: Supplemental data

Journal Articles

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

Yuichiro Nakata, Takeshi Ueda, Akiko Nagamachi, Norimasa Yamasaki, Ken-ichiro Ikeda, Yasuyuki Sera, Keiyo Takubo, Akinori Kanai, Hideaki Oda, Masashi Sanada, Seishi Ogawa, Kohichiro Tsuji, Yasuhiro Ebihara, Linda Wolff, Zen-ichiro Honda, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2017) 129 (15): 2148–2160.

https://doi.org/10.1182/blood-2016-06-724658

Published: 2017

Includes: Supplemental data

Journal Articles

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Takeshi Ueda, Akiko Nagamachi, Keiyo Takubo, Norimasa Yamasaki, Hirotaka Matsui, Akinori Kanai, Yuichiro Nakata, Kenichiro Ikeda, Takaaki Konuma, Hideaki Oda, Linda Wolff, Zen-ichiro Honda, Xudong Wu, Kristian Helin, Atsushi Iwama, Toshio Suda, Toshiya Inaba, Hiroaki Honda

Blood (2015) 125 (22): 3437–3446.

https://doi.org/10.1182/blood-2014-03-562694

Published: 2015

Includes: Supplemental data

Journal Articles

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Yuichiro Nakata, Takeshi Ueda, MD PhD, Akiko Nagamachi, PhD, Linda Wolff, PhD, Ogawa Seishi, MD, Toshiya Inaba, MD, Hiroaki Honda, MD PhD

Blood (2014) 124 (21): 4602.

https://doi.org/10.1182/blood.V124.21.4602.4602

Published: 2014

Journal Articles

Retroviral Insertional Mutagenesis In Egr1 +/- mice, Haploinsufficient For a Human Del(5q) Myeloid Leukemia Gene, Develop Myeloid Neoplasms With Proviral Insertions In Genes Syntenic To Human 5q

Angela Stoddart, PhD, Anthony Fernald, Rachel Joy Bergerson, PhD, Jianghong Wang, M.D., Megan E. McNerney, MD, PhD, Theodore Karrison, Ph.D., John Anastasi, MD, Elizabeth Bartom, Ph.D., Aaron G. Sarver, Ph.D., Zhijian Qian, PhD, Linda Wolff, PhD, David A. Largaespada, PhD, Michelle M. le Beau, PhD

Blood (2013) 122 (21): 1275.

https://doi.org/10.1182/blood.V122.21.1275.1275

Published: 2013

Journal Articles

Sox4 cooperates with CREB in myeloid transformation

Salemiz Sandoval, Christina Kraus, Er-Chieh Cho, Michelle Cho, Juraj Bies, Elena Manara, Benedetta Accordi, Elliot M. Landaw, Linda Wolff, Martina Pigazzi, Kathleen M. Sakamoto

Blood (2012) 120 (1): 155–165.

https://doi.org/10.1182/blood-2011-05-357418

Published: 2012

Includes: Supplemental data

Journal Articles

The tumor suppressor p15Ink4b regulates the differentiation and maturation of conventional dendritic cells

Joanna Fares, Richard Koller, Rita Humeniuk, Linda Wolff, Juraj Bies

Blood (2012) 119 (21): 5005–5015.

https://doi.org/10.1182/blood-2011-10-387613

Published: 2012

Journal Articles

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Blood (2012) 119 (19): 4512–4523.

https://doi.org/10.1182/blood-2010-04-281428

Published: 2012

Includes: Supplemental data

Journal Articles

Modulation of Myeloid-Derived Dendritic Cell Maturity: Unmasking a Novel Role for the Tumor Suppressor p15Ink4b in Immunity

Joanna Fares, MSc, Linda Wolff, PhD, Juraj Bies, PhD

Blood (2011) 118 (21): 2469.

https://doi.org/10.1182/blood.V118.21.2469.2469

Published: 2011

Journal Articles

Sox4 and CREB Cooperate in Myeloid Transformation,

Salemiz Sandoval, Ph.D., Michelle Cho, Christina Kraus, Er-Chieh Cho, Ph.D., Linda Wolff, PhD, Kathleen M Sakamoto, MD, PhD

Blood (2011) 118 (21): 3452.

https://doi.org/10.1182/blood.V118.21.3452.3452

Published: 2011

Journal Articles

Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras G12D from the endogenous locus

Qing Li, Kevin M. Haigis, Andrew McDaniel, Emily Harding-Theobald, Scott C. Kogan, Keiko Akagi, Jasmine C. Y. Wong, Benjamin S. Braun, Linda Wolff, Tyler Jacks, Kevin Shannon

Blood (2011) 117 (6): 2022–2032.

https://doi.org/10.1182/blood-2010-04-280750

Published: 2011

Includes: Supplemental data

Journal Articles

Use of CALM-AF10 and NUP98-HOXD13 fusions to Identify Oncogenic Pathways That Collaborate with HOXA9 Overexpression

Rachel L Novak, PhD, David P Harper, MD, David L. Caudell, DVM, PhD, Sarah H Beachy, PhD, Yang Jo Chung, PhD, Linda Wolff, PhD, Peter Aplan, MD

Blood (2010) 116 (21): 2499.

https://doi.org/10.1182/blood.V116.21.2499.2499

Published: 2010

Journal Articles

Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia

Juraj Bies, Marek Sramko, Joanna Fares, Michael Rosu-Myles, Steven Zhang, Richard Koller, Linda Wolff

Blood (2010) 116 (6): 979–987.

https://doi.org/10.1182/blood-2009-08-238360

Published: 2010

Includes: Supplemental data

Journal Articles

Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies

Jasmine C. Y. Wong, Yan Zhang, Kenneth H. Lieuw, Mary T. Tran, Erna Forgo, Kelley Weinfurtner, Pilar Alzamora, Scott C. Kogan, Keiko Akagi, Linda Wolff, Michelle M. Le Beau, Nigel Killeen, Kevin Shannon

Blood (2010) 115 (22): 4524–4532.

https://doi.org/10.1182/blood-2009-07-232504

Published: 2010

Includes: Supplemental data

Journal Articles

Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML

Thomas A. Paul, Juraj Bies, Donald Small, Linda Wolff

Blood (2010) 115 (15): 3098–3108.

https://doi.org/10.1182/blood-2009-07-233858

Published: 2010

Includes: Supplemental data

Journal Articles

Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice

David Caudell, David P. Harper, Rachel L. Novak, Rachel M. Pierce, Christopher Slape, Linda Wolff, Peter D. Aplan

Blood (2010) 115 (6): 1194–1203.

https://doi.org/10.1182/blood-2009-04-216184

Published: 2010

Includes: Supplemental data

Journal Articles

Retroviral Insertional Mutagenesis Reveals Genes That Cooperate with FLT3-ITD in Leukemogenesis.

Kathleen E Greenberg, BS, Li Li, MD, PhD, David Huso, Linda Wolff, PhD, Donald Small, MD, PhD

Blood (2009) 114 (22): 1960.

https://doi.org/10.1182/blood.V114.22.1960.1960

Published: 2009

Journal Articles

An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis.

Rachel Joy Bergerson, Lara S Collier, PhD, Sanne Lugthart, MD, Raha Allaei, Molly J Nixon, Kevin A.T. Silverstein, PhD, Aaron Sarver, PhD, Danhua Flora Fan, PhD, Anne-Francoise J Lamblin, PhD, Linda Wolff, PhD, John H. Kersey, MD, M. Gerard O'Sullivan, MVB, PhD, Ruud Delwel, PhD, Scott C. Kogan, MD, David J Adams, PhD, David Largaespada, PhD

Blood (2009) 114 (22): 3962.

https://doi.org/10.1182/blood.V114.22.3962.3962

Published: 2009

Journal Articles

Identification of Genes That Collaborate with CALM-AF10 to Induce Leukemia by Retroviral Insertional Mutagenesis and Candidate Gene Sequencing

David Caudell, DVM, PhD, Rachel M. Pierce, David P. Harper, MD, Rachel L. Novak, PhD, Christopher Slape, PhD, Linda Wolff, PhD, Peter D. Aplan, MD

Blood (2008) 112 (11): 3787.

https://doi.org/10.1182/blood.V112.11.3787.3787

Published: 2008

Journal Articles

Histone Modifications Associated with DNA Methylation and Transcriptional Repression of p15INK4b in Acute Myeloid Leukemia.

Thomas A. Paul, PhD, Horatiu Muresan, Emily Prentice, Linda Wolff, PhD

Blood (2008) 112 (11): 3354.

https://doi.org/10.1182/blood.V112.11.3354.3354

Published: 2008

NARROW

UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes

Acquired expression of Cbl Q367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

Generation and Analysis of a Novel Mouse Model for Chronic Myelomonocytic Leukemia (CMML) with Acquired Expression of c-CBL Q367P

Retroviral Insertional Mutagenesis In Egr1 +/- mice, Haploinsufficient For a Human Del(5q) Myeloid Leukemia Gene, Develop Myeloid Neoplasms With Proviral Insertions In Genes Syntenic To Human 5q

Sox4 cooperates with CREB in myeloid transformation

The tumor suppressor p15Ink4b regulates the differentiation and maturation of conventional dendritic cells

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Modulation of Myeloid-Derived Dendritic Cell Maturity: Unmasking a Novel Role for the Tumor Suppressor p15Ink4b in Immunity

Sox4 and CREB Cooperate in Myeloid Transformation,

Hematopoiesis and leukemogenesis in mice expressing oncogenic Nras G12D from the endogenous locus

Use of CALM-AF10 and NUP98-HOXD13 fusions to Identify Oncogenic Pathways That Collaborate with HOXA9 Overexpression

Myeloid-specific inactivation of p15Ink4b results in monocytosis and predisposition to myeloid leukemia

Use of chromosome engineering to model a segmental deletion of chromosome band 7q22 found in myeloid malignancies

Signatures of polycomb repression and reduced H3K4 trimethylation are associated with p15INK4b DNA methylation in AML

Retroviral insertional mutagenesis identifies Zeb2 activation as a novel leukemogenic collaborating event in CALM-AF10 transgenic mice

Retroviral Insertional Mutagenesis Reveals Genes That Cooperate with FLT3-ITD in Leukemogenesis.

An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis.

Identification of Genes That Collaborate with CALM-AF10 to Induce Leukemia by Retroviral Insertional Mutagenesis and Candidate Gene Sequencing

Histone Modifications Associated with DNA Methylation and Transcriptional Repression of p15INK4b in Acute Myeloid Leukemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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