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Journal Articles

EVI1 is critical for the pathogenesis of a subset of MLL-AF9 –rearranged AMLs

Eric M. J. Bindels, Marije Havermans, Sanne Lugthart, Claudia Erpelinck, Elizabeth Wocjtowicz, Andrei V. Krivtsov, Elwin Rombouts, Scott A. Armstrong, Erdogan Taskesen, Jurgen R. Haanstra, H. Berna Beverloo, Hartmut Döhner, Wendy A. Hudson, John H. Kersey, Ruud Delwel, Ashish R. Kumar

Blood (2012) 119 (24): 5838–5849.

https://doi.org/10.1182/blood-2011-11-393827

Published: 2012

Includes: Supplemental data

Journal Articles

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Blood (2012) 119 (19): 4512–4523.

https://doi.org/10.1182/blood-2010-04-281428

Published: 2012

Includes: Supplemental data

Journal Articles

Burden of Morbidity in 10+ Year Survivors of Hematopoietic Cell Transplantation (HCT): A Report From the Bone Marrow Transplant Survivor Study (BMTSS)

Can-Lan Sun, Ph.D, John H. Kersey, MD, Liton Francisco, B.S., K. Scott Baker, MD, MS, Saro H. Armenian, DO, MPH, Daniel J. Weisdorf, MD, Forman Stephen, M.D., Smita Bhatia, MD, MPH

Blood (2011) 118 (21): 841.

https://doi.org/10.1182/blood.V118.21.841.841

Published: 2011

Journal Articles

Meis1 maintains stemness signature in MLL-AF9 leukemia

Ashish R. Kumar, Aaron L. Sarver, Baolin Wu, John H. Kersey

Blood (2010) 115 (17): 3642–3643.

https://doi.org/10.1182/blood-2010-01-264564

Published: 2010

Journal Articles

Infant ALL: diverse origins and outcomes

Ashish R. Kumar, John H. Kersey

Blood (2010) 115 (14): 2725.

https://doi.org/10.1182/blood-2010-01-262741

Published: 2010

Journal Articles

An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis.

Rachel Joy Bergerson, Lara S Collier, PhD, Sanne Lugthart, MD, Raha Allaei, Molly J Nixon, Kevin A.T. Silverstein, PhD, Aaron Sarver, PhD, Danhua Flora Fan, PhD, Anne-Francoise J Lamblin, PhD, Linda Wolff, PhD, John H. Kersey, MD, M. Gerard O'Sullivan, MVB, PhD, Ruud Delwel, PhD, Scott C. Kogan, MD, David J Adams, PhD, David Largaespada, PhD

Blood (2009) 114 (22): 3962.

https://doi.org/10.1182/blood.V114.22.3962.3962

Published: 2009

Journal Articles

A role for MEIS1 in MLL -fusion gene leukemia

Ashish R. Kumar, Quanzhi Li, Wendy A. Hudson, Weili Chen, Thien Sam, Qing Yao, Erik A. Lund, Baolin Wu, Branden J. Kowal, John H. Kersey

Blood (2009) 113 (8): 1756–1758.

https://doi.org/10.1182/blood-2008-06-163287

Published: 2009

Includes: Supplemental data

Journal Articles

A MEIS1 Dependent Genetic Program in Leukemia Associated with Cell Cycle Entry and ‘Stemness’

Ashish Kumar, MBBS, PhD, Baolin Wu, John H. Kersey, MD

Blood (2008) 112 (11): 746.

https://doi.org/10.1182/blood.V112.11.746.746

Published: 2008

Journal Articles

Mll-AF9 Initiates Fetal Hematopoietic Stem Cell Transformation but Development of Overt Leukemia Requires Additional Events in Post-Natal Cells

Weili Chen, Wendy A Hudson, Thien N Sam, John H. Kersey, MD

Blood (2008) 112 (11): 2840.

https://doi.org/10.1182/blood.V112.11.2840.2840

Published: 2008

Journal Articles

Evi1 Promotes Leukemogenesis by Anti-Apoptotic Rather Than Differentiation-Blocking Effects in Murine MLL-AF9 Leukemia

Ashish Kumar, MBBS, PhD, Quanzhi Li, PhD, Wendy A Hudson, Thien N Sam, Weili Chen, John H Kersey, MD

Blood (2008) 112 (11): 593.

https://doi.org/10.1182/blood.V112.11.593.593

Published: 2008

Journal Articles

Novel Mll-AF9 Cooperating Genes Identified in a Leukemogenesis Screen Using Retroviral Mutagenesis.

Rachel J. Bergerson, BA, Lara S. Collier, PhD, Raha Allaei, BS, Kevin A. Silverstein, PhD, Anne-Francoise F. Lamblin, PhD, Linda Wolff, PhD, Scott C. Kogan, MD, John H. Kersey, MD, David J. Adams, PhD, David A. Largaespada, PhD

Blood (2007) 110 (11): 825.

https://doi.org/10.1182/blood.V110.11.825.825

Published: 2007

Journal Articles

MEIS1 Is a Promising New Target for Leukemia Therapy.

Ashish Kumar, MD, PhD, Quanzhi Li, PhD, Weili Chen, Wendy A. Hudson, John H. Kersey, MD

Blood (2007) 110 (11): 872.

https://doi.org/10.1182/blood.V110.11.872.872

Published: 2007

Journal Articles

A Screen for Mll-AF9 Cooperating Mutations in Leukemogenesis Using MLV-Based Mutagenesis.

Rachel J.S. Bergerson, Lara S. Collier, PhD, Tony Cox, PhD, Wendy A. Hudson, Raha Allaei, Linda Wolff, PhD, John H. Kersey, MD, David J. Adams, PhD, David A. Largaespada, PhD

Blood (2006) 108 (11): 1417.

https://doi.org/10.1182/blood.V108.11.1417.1417

Published: 2006

Journal Articles

Differential Expression of Mll-AF9 Up-Regulated Genes Correlates with Enhanced Self-Renewal of Hematopoietic Progenitors.

Ashish R. Kumar, MD, PhD, Wendy A. Hudson, Weili Chen, Rodney A. Staggs, Anne-Francoise Lamblin, PhD, John H. Kersey, MD

Blood (2006) 108 (11): 733.

https://doi.org/10.1182/blood.V108.11.733.733

Published: 2006

Journal Articles

The Mll-AF9 Knock-In Fusion Gene Results in Reprogramming and Enhanced Self-Renewal of Hematopoietic Progenitors, Especially in the HSC and CLP Populations.

Weili Chen, Ashish R. Kumar, Wendy A. Hudson, Quanzhi Li, John H. Kersey

Blood (2006) 108 (11): 1421.

https://doi.org/10.1182/blood.V108.11.1421.1421

Published: 2006

Journal Articles

A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy

Weili Chen, Quanzhi Li, Wendy A. Hudson, Ashish Kumar, Nicole Kirchhof, John H. Kersey

Blood (2006) 108 (2): 669–677.

https://doi.org/10.1182/blood-2005-08-3498

Published: 2006

Includes: Supplemental data

Journal Articles

The Mll-AF9 Fusion Gene Results in Overexpression of Homeobox Genes and Deregulation of Granulocyte-Monocyte Progenitors.

Ashish Kumar, Weili Chen, John H. Kersey

Blood (2005) 106 (11): 645.

https://doi.org/10.1182/blood.V106.11.645.645

Published: 2005

Journal Articles

The Hsp90 Inhibitor 17-AAG and FLT3 Kinase Inhibitor GTP14564 Synergistically Inhibit MLL Fusion Gene Leukemias with FLT3 Mutations.

Qing Yao, Ph.D, Ritsuo Nishiuchi, M.D, Ph. D, Toshio Kitamura, M.D, John H. Kersey, M.D

Blood (2004) 104 (11): 1167.

https://doi.org/10.1182/blood.V104.11.1167.1167

Published: 2004

Journal Articles

MLL-AF9 and MLL-ENL Induce Deregulation of Similar Downstream Candidate Genes: An Analysis across Experimental Protocols and Laboratories.

Ashish R. Kumar, MD, PhD, Robert K. Slany, PhD, Jay L. Hess, MD, PhD, John H. Kersey, MD

Blood (2004) 104 (11): 3372.

https://doi.org/10.1182/blood.V104.11.3372.3372

Published: 2004

Journal Articles

The Expression of Genes 5′ in the Hox-A Cluster Is Co-Ordinated Both in Normal and Leukemic Hematopoiesis.

Ashish R. Kumar, MD, PhD, John H. Kersey, MD

Blood (2004) 104 (11): 3560.

https://doi.org/10.1182/blood.V104.11.3560.3560

Published: 2004

NARROW

EVI1 is critical for the pathogenesis of a subset of MLL-AF9 –rearranged AMLs

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Burden of Morbidity in 10+ Year Survivors of Hematopoietic Cell Transplantation (HCT): A Report From the Bone Marrow Transplant Survivor Study (BMTSS)

Meis1 maintains stemness signature in MLL-AF9 leukemia

Infant ALL: diverse origins and outcomes

An Insertional Mutagenesis Screen for Genes That Cooperate with Mll-AF9 in Leukemogenesis.

A role for MEIS1 in MLL -fusion gene leukemia

A MEIS1 Dependent Genetic Program in Leukemia Associated with Cell Cycle Entry and ‘Stemness’

Mll-AF9 Initiates Fetal Hematopoietic Stem Cell Transformation but Development of Overt Leukemia Requires Additional Events in Post-Natal Cells

Evi1 Promotes Leukemogenesis by Anti-Apoptotic Rather Than Differentiation-Blocking Effects in Murine MLL-AF9 Leukemia

Novel Mll-AF9 Cooperating Genes Identified in a Leukemogenesis Screen Using Retroviral Mutagenesis.

MEIS1 Is a Promising New Target for Leukemia Therapy.

A Screen for Mll-AF9 Cooperating Mutations in Leukemogenesis Using MLV-Based Mutagenesis.

Differential Expression of Mll-AF9 Up-Regulated Genes Correlates with Enhanced Self-Renewal of Hematopoietic Progenitors.

The Mll-AF9 Knock-In Fusion Gene Results in Reprogramming and Enhanced Self-Renewal of Hematopoietic Progenitors, Especially in the HSC and CLP Populations.

A murine Mll-AF4 knock-in model results in lymphoid and myeloid deregulation and hematologic malignancy

The Mll-AF9 Fusion Gene Results in Overexpression of Homeobox Genes and Deregulation of Granulocyte-Monocyte Progenitors.

The Hsp90 Inhibitor 17-AAG and FLT3 Kinase Inhibitor GTP14564 Synergistically Inhibit MLL Fusion Gene Leukemias with FLT3 Mutations.

MLL-AF9 and MLL-ENL Induce Deregulation of Similar Downstream Candidate Genes: An Analysis across Experimental Protocols and Laboratories.

The Expression of Genes 5′ in the Hox-A Cluster Is Co-Ordinated Both in Normal and Leukemic Hematopoiesis.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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