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Journal Articles

Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling

Erdogan Taskesen, Marije Havermans, Kirsten van Lom, Mathijs A. Sanders, Yvette van Norden, Eric Bindels, Remco Hoogenboezem, Marcel J. T. Reinders, Maria E. Figueroa, Peter J. M. Valk, Bob Löwenberg, Ari Melnick, Ruud Delwel
Journal: Blood
Blood (2014) 123 (21): 3327–3335.
https://doi.org/10.1182/blood-2013-07-512855
Published: 2014
Includes: Supplemental data
Journal Articles

The value of allogeneic and autologous hematopoietic stem cell transplantation in prognostically favorable acute myeloid leukemia with double mutant CEBPA

Clinical Trials & Observations
Richard F. Schlenk, Erdogan Taskesen, Yvette van Norden, Jürgen Krauter, Arnold Ganser, Lars Bullinger, Verena I. Gaidzik, Peter Paschka, Andrea Corbacioglu, Gudrun Göhring, Andrea Kündgen, Gerhard Held, Katharina Götze, Edo Vellenga, Juergen Kuball, Urs Schanz, Jakob Passweg, Thomas Pabst, Johan Maertens, Gert J. Ossenkoppele, Ruud Delwel, Hartmut Döhner, Jan J. Cornelissen, Konstanze Döhner, Bob Löwenberg
Journal: Blood
Blood (2013) 122 (9): 1576–1582.
https://doi.org/10.1182/blood-2013-05-503847
Published: 2013
Includes: Supplemental data
Journal Articles

EVI1 is critical for the pathogenesis of a subset of MLL-AF9 –rearranged AMLs

Clinical Trials & Observations
Eric M. J. Bindels, Marije Havermans, Sanne Lugthart, Claudia Erpelinck, Elizabeth Wocjtowicz, Andrei V. Krivtsov, Elwin Rombouts, Scott A. Armstrong, Erdogan Taskesen, Jurgen R. Haanstra, H. Berna Beverloo, Hartmut Döhner, Wendy A. Hudson, John H. Kersey, Ruud Delwel, Ashish R. Kumar
Journal: Blood
Blood (2012) 119 (24): 5838–5849.
https://doi.org/10.1182/blood-2011-11-393827
Published: 2012
Includes: Supplemental data
Journal Articles

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

Rastislav Horos, Hanna IJspeert, Dagmar Pospisilova, Regine Sendtner, Charlotte Andrieu-Soler, Erdogan Taskesen, Andrzej Nieradka, Radek Cmejla, Michael Sendtner, Ivo P. Touw, Marieke von Lindern
Journal: Blood
Blood (2012) 119 (1): 262–272.
https://doi.org/10.1182/blood-2011-06-358200
Published: 2012
Includes: Supplemental data
Journal Articles

CEBPα Is a Transcriptional Repressor of T-Cell Related Genes Explaining the Myeloid/T-Lymphoid Features of CEBPα-Silenced AML

Erdogan Taskesen, Roberto Avellino, Meritxell AlberichJorda, Daniel G. Tenen, Jeroen Ridder de, Peter Valk, Bas Wouters, Claudia Erpelinck, Marcel Reinders, Ruud Delwel, Ph.D.
Journal: Blood
Blood (2011) 118 (21): 554.
https://doi.org/10.1182/blood.V118.21.554.554
Published: 2011
Journal Articles

Methylated Retroviral Integration Mutagenesis (MRIM) in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression As a Prognostic Indicator

Renee Beekman, MD, Marijke G. Valkhof, Stefan J. Erkeland, PhD, Erdogan Taskesen, Veronika Rockova, Justine K. Peeters, PhD, Peter Valk, Bob Lowenberg, MD, PhD, Ivo P. Touw, PhD
Journal: Blood
Blood (2011) 118 (21): 746.
https://doi.org/10.1182/blood.V118.21.746.746
Published: 2011
Journal Articles

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1–regulated pathways in mice

Annemarie Meenhuis, Peter A. van Veelen, Hans de Looper, Nicole van Boxtel, Iris J. van den Berge, Su M. Sun, Erdogan Taskesen, Patrick Stern, Arnoud H. de Ru, Arjan J. van Adrichem, Jeroen Demmers, Mojca Jongen-Lavrencic, Bob Löwenberg, Ivo P. Touw, Phillip A. Sharp, Stefan J. Erkeland
Journal: Blood
Blood (2011) 118 (4): 916–925.
https://doi.org/10.1182/blood-2011-02-336487
Published: 2011
Includes: Supplemental data
Journal Articles

Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA double mutant AML as a distinctive disease entity

Clinical Trials & Observations
Erdogan Taskesen, Lars Bullinger, Andrea Corbacioglu, Mathijs A. Sanders, Claudia A. J. Erpelinck, Bas J. Wouters, Sonja C. van der Poel-van de Luytgaarde, Frederik Damm, Jürgen Krauter, Arnold Ganser, Richard F. Schlenk, Bob Löwenberg, Ruud Delwel, Hartmut Döhner, Peter J. M. Valk, Konstanze Döhner
Journal: Blood
Blood (2011) 117 (8): 2469–2475.
https://doi.org/10.1182/blood-2010-09-307280
Published: 2011
Includes: Supplemental data
Journal Articles

Loss of RAF Kinase Inhibitor Protein Is a Frequent Event In Acute Myeloid Leukemia with a Monocytic Phenotype and Cooperates with Mutant RAS In Malignant Transformation

Armin Zebisch, PhD, Albert Woelfler, PhD, Karin Hiden, PhD, Claudia Bodner, PhD, Franz Quehenberger, PhD, Astrid Drasche, PhD, Daniela Pirkebner, PhD, Martina Haller, PhD, Oliver Rath, PhD, Karen Blyth, PhD, Erdogan Taskesen, PhD, Walter Kolch, PhD, Jakob Troppmair, Heinz Sill, MD
Journal: Blood
Blood (2010) 116 (21): 4185.
https://doi.org/10.1182/blood.V116.21.4185.4185
Published: 2010
Journal Articles

Ribosomal Deficiencies Cause Translational Deregulation of Genes Crucial for Erythropoiesis.

Rastislav Horos, Hanna IJspeert, Erdogan Taskesen, Ruud H Delwel, Dagmar Pospisilova, Marieke M von Lindern
Journal: Blood
Blood (2009) 114 (22): 179.
https://doi.org/10.1182/blood.V114.22.179.179
Published: 2009