1-14 of 14
Eric Bindels
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Hematological Phenotypes in GATA2 Deficiency Syndrome Arise from Secondary Injuries and Maladaptation to Proliferation

Juncal Fernandez Orth, Cansu Koyunlar, Julia Miriam Weiss, Emanuele Gioacchino, Hans De Looper, Geoffroy Andrieux, Mariëtte Ter Borg, Joke Zink, Irene Gonzalez-Menendez, Remco Hoogenboezem, Baris Yigit, Kirsten Gussinklo, Roger Mulet-Lazaro, Marc Raaijmakers, Irene Gonzalez Menendez, Charlotte Wantzen, Sophie Pfeiffer, Christian Molnar, Eric Bindels, Sheila Bohler, Mathijs Arnoud Sanders, Leticia Quintanilla-Fend, Marcin Wlodarski, Melanie Boerries, Ivo Paul Touw, Charlotte Marie Niemeyer, Miriam Erlacher, Emma De Pater
Journal: Blood
Blood (2024) 144 (Supplement 1): 442.
https://doi.org/10.1182/blood-2024-205165
Published: 2024
Journal Articles

Targeting Super-Enhancers Driving EVI1 Expression in Leukemia By Inhibition of p300/CBP

Dorien Pastoors, Claudia Erpelinck, Stanley Van Herk, Roger Mulet-Lazaro, Marije Havermans, Eric Bindels, Sophie Ottema, Ruud Delwel
Journal: Blood
Blood (2023) 142 (Supplement 1): 710.
https://doi.org/10.1182/blood-2023-181741
Published: 2023
Journal Articles

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable EVI1-CtBP1/2 Interaction and By Repressing Myeloid Regulator CEBPA

Dorien Pastoors, Marije Havermans, Remco Hoogenboezem, Roger Mulet-Lazaro, Duncan Brian, Leonie Smeenk, Claudia Erpelinck-Verschueren, Stanley van Herk, Bas Wouters, Jeroen A.A. Demmers, Johannes Zuber, Tariq Enver, Richard WJ Groen, Eric Bindels, Ruud Delwel
Journal: Blood
Blood (2022) 140 (Supplement 1): 83–84.
https://doi.org/10.1182/blood-2022-156994
Published: 2022
Journal Articles

Allele-specific expression of GATA2 due to epigenetic dysregulation in CEBPA double-mutant AML

Roger Mulet-Lazaro, Stanley van Herk, Claudia Erpelinck, Eric Bindels, Mathijs A. Sanders, Carlo Vermeulen, Ivo Renkens, Peter Valk, Ari M. Melnick, Jeroen de Ridder, Michael Rehli, Claudia Gebhard, Ruud Delwel, Bas J. Wouters
Journal: Blood
Blood (2021) 138 (2): 160–177.
https://doi.org/10.1182/blood.2020009244
Published: 2021
Includes: Supplemental data
Journal Articles

Atypical 3q26/ MECOM rearrangements genocopy inv(3)/t(3;3) in acute myeloid leukemia

Sophie Ottema, Roger Mulet-Lazaro, H. Berna Beverloo, Claudia Erpelinck, Stanley van Herk, Robert van der Helm, Marije Havermans, Tim Grob, Peter J. M. Valk, Eric Bindels, Torsten Haferlach, Claudia Haferlach, Leonie Smeenk, Ruud Delwel
Journal: Blood
Blood (2020) 136 (2): 224–234.
https://doi.org/10.1182/blood.2019003701
Published: 2020
Includes: Supplemental data
Journal Articles

PML Plays a Key Role in Severe Congenital Neutropenia with Mutant ELANE Causing Neutrophil Elastase Protein Misfolding

Patricia Olofsen, MSc, Paulette van Strien, BSc, Onno Roovers, BSc, Hans De Looper, BSc, Remco Hoogenboezem, MSc, Dennis Bosch, BSc, Mehrnaz Ghazvini, PhD, Eric Bindels, PhD, Emma De Pater, PhD, Ivo Touw, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 213.
https://doi.org/10.1182/blood-2019-122423
Published: 2019
Journal Articles

Allele-Specific Expression of GATA2 in AML with CEBPA Biallelic Mutations

Roger Mulet-Lazaro, MSc, Stanley van Herk, B.Sc., Claudia Erpelinck-Verschueren, B.Sc., Mathijs A. Sanders, PhD MSc, Eric Bindels, PhD, Peter Valk, PhD, Michael Rehli, PhD, Claudia Gebhard, PhD, Ruud Delwel, PhD, B.J. Wouters
Journal: Blood
Blood (2019) 134 (Supplement_1): 1235.
https://doi.org/10.1182/blood-2019-129766
Published: 2019
Journal Articles

Temporal autoregulation during human PU.1 locus SubTAD formation

Daniel Schuetzmann, Carolin Walter, Boet van Riel, Sabrina Kruse, Thorsten König, Tabea Erdmann, Alexander Tönges, Eric Bindels, Andre Weilemann, Claudia Gebhard, Klaus Wethmar, Chiara Perrod, Julia Minderjahn, Michael Rehli, Ruud Delwel, Georg Lenz, Stefan Gröschel, Martin Dugas, Frank Rosenbauer
Journal: Blood
Blood (2018) 132 (25): 2643–2655.
https://doi.org/10.1182/blood-2018-02-834721
Published: 2018
Includes: Supplemental data
Journal Articles

Complex 3q26/EVI1 Rearrangements Genocopy Inv(3)/t(3;3) Acute Myeloid Leukemias By Enhancer Hijacking, EVI1 Overexpression, Absent MDS1-EVI1 and Low GATA2 Expression

Sophie Ottema, MSc, Roger Mulet-Lazaro, B.Sc., Berna Beverloo, PhD, Marije Havermans, Ir, Claudia Erpelinck-Verschueren, B.Sc., Tim Grob, MD, Peter Valk, PhD, Eric Bindels, PhD, Torsten Haferlach, MD, Claudia Haferlach, MD, Leonie Smeenk, PhD, Ruud Delwel, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2766.
https://doi.org/10.1182/blood-2018-99-113339
Published: 2018
Journal Articles

Inflammatory Niche Signalling Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Leukemic Evolution in Human Leukemia Predisposition Syndromes

Si Chen, MSCs, Noemi A. Zambetti, PhD, Zhen Ping, MSCs, Keane Kenswil, MSCs, Maria Mylona, PhD, Mathijs A. Sanders, PhD, Remco Hoogenboezem, MSc, Eric Bindels, PhD, Maria Adisty, Paulina M. H. van Strien, B.Sc., Cindy van der Leije, Theresia M Westers, PhD, Eline MP Cremers, MD, Chiara Milanese, PhD, Pier Mastroberardino, PhD, Johannes van Leeuwen, PhD, Bram Van der Eerden, PhD, Ivo Touw, PhD, Kuijpers Taco, Roland Kanaar, PhD, Arjan van der Loosdrecht, MD PhD, Thomas Vogl, PhD, Marc H.G.P. Raaijmakers, MD PhD
Journal: Blood
Blood (2016) 128 (22): 428.
https://doi.org/10.1182/blood.V128.22.428.428
Published: 2016
Journal Articles

An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Roberto Avellino, Marije Havermans, Claudia Erpelinck, Mathijs A. Sanders, Remco Hoogenboezem, Harmen J. G. van de Werken, Elwin Rombouts, Kirsten van Lom, Paulina M. H. van Strien, Claudia Gebhard, Michael Rehli, John Pimanda, Dominik Beck, Stefan Erkeland, Thijs Kuiken, Hans de Looper, Stefan Gröschel, Ivo Touw, Eric Bindels, Ruud Delwel
Journal: Blood
Blood (2016) 127 (24): 2991–3003.
https://doi.org/10.1182/blood-2016-01-695759
Published: 2016
Includes: Supplemental data
Journal Articles

A Myeloid-Specific Gene-Dosage Regulator for CEBPA Expression in Myeloid Cells Is Commonly Targeted By Onco-Proteins in AML

Roberto Avellino, Stefan M Groschel, MD, Harmen Van de Werken, Mathijs A. Sanders, MSc, Remco M. Hoogenboezem, Claudia Erpelinck, Marije Havermans, Eric Bindels, Ruud Delwel, PhD
Journal: Blood
Blood (2014) 124 (21): 2205.
https://doi.org/10.1182/blood.V124.21.2205.2205
Published: 2014
Journal Articles

Two splice-factor mutant leukemia subgroups uncovered at the boundaries of MDS and AML using combined gene expression and DNA-methylation profiling

Erdogan Taskesen, Marije Havermans, Kirsten van Lom, Mathijs A. Sanders, Yvette van Norden, Eric Bindels, Remco Hoogenboezem, Marcel J. T. Reinders, Maria E. Figueroa, Peter J. M. Valk, Bob Löwenberg, Ari Melnick, Ruud Delwel
Journal: Blood
Blood (2014) 123 (21): 3327–3335.
https://doi.org/10.1182/blood-2013-07-512855
Published: 2014
Includes: Supplemental data
Journal Articles

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

Sanne Lugthart, Maria E. Figueroa, Eric Bindels, Lucy Skrabanek, Peter J. M. Valk, Yushan Li, Stefan Meyer, Claudia Erpelinck-Verschueren, John Greally, Bob Löwenberg, Ari Melnick, Ruud Delwel
Journal: Blood
Blood (2011) 117 (1): 234–241.
https://doi.org/10.1182/blood-2010-04-281337
Published: 2011
Includes: Supplemental data