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Journal Articles

Myelodysplastic Syndrome Marrow Stroma Shows Widespread Aberrant Hypermethylation That Is Abrogated By Treatment with Dnmt Inhibitors

Tushar D Bhagat, PhD, Matthias Bartenstein, MD, Yiting Yu, PhD, A. Mario Q. Marcondes, MD PhD, Britta Will, PhD, Orsolya Giricz, PhD, Davendra P. Sohal, MD MPH, Ioannis Mantzaris, MD, Amittha Wickrema, PhD, Christine Mcmahon, MD, Yeung Cecilia, MD, John Greally, MB, PhD, Siddhartha Mukherjee, MD PhD, Ulrich Steidl, MD PhD, H. Joachim Deeg, MD, Amit Verma, MD

Blood (2014) 124 (21): 4379.

https://doi.org/10.1182/blood.V124.21.4379.4379

Published: 2014

Journal Articles

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

Sanne Lugthart, Maria E. Figueroa, Eric Bindels, Lucy Skrabanek, Peter J. M. Valk, Yushan Li, Stefan Meyer, Claudia Erpelinck-Verschueren, John Greally, Bob Löwenberg, Ari Melnick, Ruud Delwel

Blood (2011) 117 (1): 234–241.

https://doi.org/10.1182/blood-2010-04-281337

Published: 2011

Includes: Supplemental data

Journal Articles

Epigenomic Profiling of Myeloproliferative Diseases Reveal Idiopathic Myelofibrosis as An Epigenetically Distinct Subgroup and Highlights the Epigenetic Effects of Jak2V617F Mutation

Sangeeta Nischal, Li Zhou, Yiting Yu, Tushar Bhagat, Yongkai Mo, Christoph Heuck, Masako Suzuki, Shahina Maqbool, Animesh Pardanani, John Greally, Alison Moliterno, Amit Verma

Blood (2010) 116 (21): 627.

https://doi.org/10.1182/blood.V116.21.627.627

Published: 2010

Journal Articles

DNA Methylation Profiling Predicts Clinical Outcomes and Reveals Unique Insights Into the Molecular Complexity of Acute Myeloid Leukemia.

Maria E Figueroa, MD, Sanne Lugthart, MD, Yushan Li, Claudia Erpelinck-Verschueren, Xutao Deng, Paul J. Christos, PhD, Elizabeth Schifano, Jim Booth, Lucy Skrabanek, Fabien Campagne, Madhu Mazumdar, PhD, John Greally, MB, PhD, Peter Valk, Bob Lowenberg, MD, PhD, Ruud Delwel, PhD, Ari Melnick

Blood (2009) 114 (22): 707.

https://doi.org/10.1182/blood.V114.22.707.707

Published: 2009

Journal Articles

Integrative Genomic Analysis Reveals Aberrant Epigenetic Marks in MDS That Can Be Seen in Peripheral Blood Leucocytes

Li Zhou, Joanna B. Opalinska, Davendra P. Sohal, Yongkai Mo, Suman Kambhampati, Simrit Parmar, Christina Alencar, Christoph Heuck, Ivette Vigoda, Chun Ng, Perry Pahanish, Swati Goel, Carolina Schinke, Lawrence Cytryn, Ellen Friedman, Maria E Figueroa, Amittha Wickrema, PhD, John Greally, Amit Verma

Blood (2008) 112 (11): 595.

https://doi.org/10.1182/blood.V112.11.595.595

Published: 2008

Journal Articles

Epigenetic Signatures Identify New Clinically Relevant Subtypes and Define Gene Regulatory Patterns in Patients with Acute Myeloid Leukemia (AML)

Maria E Figueroa, MD, Sanne Lugthart, MD, Yushan Li, Claudia Erpelinck-Verschueren, Paul J Christos, MS, MPH, Madhu Mazumdar, PhD, Bob Löwenberg, MD, PhD, John Greally, MB, PhD, Peter JM Valk, PhD, Ruud Delwel, PhD, Ari Melnick, MD

Blood (2008) 112 (11): 756.

https://doi.org/10.1182/blood.V112.11.756.756

Published: 2008

Journal Articles

Two Different EVI1 Expressing Poor-Risk AML Subgroups with Distinct Epigenetic Signatures Uncovered by Genome Wide DNA Methylation Profiling

Sanne Lugthart, MD, Maria E Figueroa, MD, Peter JM Valk, PhD, Yushan Li, Claudia Erpelinck-Verschueren, John Greally, MB, PhD, Bob Löwenberg, MD, PhD, Ari Melnick, MD, Ruud Delwel, PhD

Blood (2008) 112 (11): 757.

https://doi.org/10.1182/blood.V112.11.757.757

Published: 2008

Journal Articles

Downregulation of Ribosomal Proteins Is Seen in Non 5q- MDS

Davendra P. Sohal, Andrea Pellagati, Li Zhou, Yongkai Mo, Joanna B. Opalinska, Christina Alencar, Christoph Heuck, Amittha Wickrema, Ellen Friedman, John Greally, Benjamin L. Ebert, Jonathan Warner, Jacqueline Boultwood, Amit Verma

Blood (2008) 112 (11): 854.

https://doi.org/10.1182/blood.V112.11.854.854

Published: 2008

Journal Articles

Genome-Wide Epigenetics in Myeloid Leukemias.

Maria Eugenia Figueroa, MD, John Greally, MB, PhD, Ruud Delwel, PhD, Ari M. Melnick, MD

Blood (2008) 112 (11): sci-35.

https://doi.org/10.1182/blood.V112.11.sci-35.sci-35

Published: 2008

Journal Articles

MDS Marrow Stroma Is Characterized by Distinct Epigenetic Alterations

Tushar D Bhagat, Emily Spaulding, Davendra Sohal, Yongkai Mo, Mario Marcondes, Li Zhou, Reid Thompson, John Greally, H. Joachim Deeg, Amit Verma

Blood (2008) 112 (11): 3635.

https://doi.org/10.1182/blood.V112.11.3635.3635

Published: 2008

Journal Articles

Increased Global Gene Promoter Methylation after Relapse (Rel) of Acute Promyelocytic Leukemia (APL) from All- trans Retinoic Acid (ATRA)-Containing Treatment Is Dissociated from Concurrent Gene Expression Changes.

Da-Cheng Zhou, MD, PhD, Qingping Cui, PhD, Haesook Kim, PhD, Reid Thompson, BS, John Greally, MD, PhD, Eric E. Bouhassira, PhD, Robert E. Gallagher, MD

Blood (2007) 110 (11): 2121.

https://doi.org/10.1182/blood.V110.11.2121.2121

Published: 2007

Journal Articles

High Resolution Epigenomic Mapping of Myelodysplastic Syndrome Reveals a High Level of Functionally Important Methylation.

Li Zhou, Joanna Opalinska, Davendra Sohal, Simrit Parmar, Perry Pahanish, Iris Isulfi, Kenny Ye, Maria Figueroa, John Greally, Ari Melnick, Amit Verma

Blood (2006) 108 (11): 2637.

https://doi.org/10.1182/blood.V108.11.2637.2637

Published: 2006

Journal Articles

A High Resolution Epigenomic Map of Myelofibrosis Reveals Multiple Chromosomal Deletions and Amplifications Accompanied by a High Level of Functionally Important Methylation.

Joanna Opalinska, Davendra Sohal, Simrit Parmar, Li Zhou, Andrew Yeatts, Perry Pahanish, Iris Isulfi, Kenny Ye, Maria Figueroa, Ari Melnick, John Greally, Amit Verma

Blood (2006) 108 (11): 2684.

https://doi.org/10.1182/blood.V108.11.2684.2684

Published: 2006

Journal Articles

Sensitivity of Diffuse Large B-Cell Lymphomas to DNA Methyltransferase Inhibitors Is Associated with a Specific Epigenetic Signature.

Megan Ryan, Leandro Cerchietti, MD, Maria E. Figueroa, MD, John Greally, MD, Ari Melnick, MD

Blood (2006) 108 (11): 831.

https://doi.org/10.1182/blood.V108.11.831.831

Published: 2006

Journal Articles

Meta-Transcriptome of Bone Marrow Stem Cells Demonstrates Platform and Lab Dependant Variability in Gene Expression and Reveals a Novel Set of Enriched Genes.

Davendra Sohal, Andrew Yeatts, Joanna Opalinska, Li Zhou, Perry Pahanish, Kenny Ye, Maria Figueroa, John Mariadason, Ari Melnick, John Greally, Amit Verma

Blood (2006) 108 (11): 4189.

https://doi.org/10.1182/blood.V108.11.4189.4189

Published: 2006

Journal Articles

Lack of Increased Gene Promoter Methylation at Relapse in Acute Promyelocytic Leukemia (APL).

Da-Cheng Zhou, MD,PhD, Reid Thompson, BS, Haesook Kim, PhD, John Greally, MD,PhD, Robert Gallagher, MD

Blood (2006) 108 (11): 4315.

https://doi.org/10.1182/blood.V108.11.4315.4315

Published: 2006

NARROW

Myelodysplastic Syndrome Marrow Stroma Shows Widespread Aberrant Hypermethylation That Is Abrogated By Treatment with Dnmt Inhibitors

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

Epigenomic Profiling of Myeloproliferative Diseases Reveal Idiopathic Myelofibrosis as An Epigenetically Distinct Subgroup and Highlights the Epigenetic Effects of Jak2V617F Mutation

DNA Methylation Profiling Predicts Clinical Outcomes and Reveals Unique Insights Into the Molecular Complexity of Acute Myeloid Leukemia.

Integrative Genomic Analysis Reveals Aberrant Epigenetic Marks in MDS That Can Be Seen in Peripheral Blood Leucocytes

Epigenetic Signatures Identify New Clinically Relevant Subtypes and Define Gene Regulatory Patterns in Patients with Acute Myeloid Leukemia (AML)

Two Different EVI1 Expressing Poor-Risk AML Subgroups with Distinct Epigenetic Signatures Uncovered by Genome Wide DNA Methylation Profiling

Downregulation of Ribosomal Proteins Is Seen in Non 5q- MDS

Genome-Wide Epigenetics in Myeloid Leukemias.

MDS Marrow Stroma Is Characterized by Distinct Epigenetic Alterations

Increased Global Gene Promoter Methylation after Relapse (Rel) of Acute Promyelocytic Leukemia (APL) from All- trans Retinoic Acid (ATRA)-Containing Treatment Is Dissociated from Concurrent Gene Expression Changes.

High Resolution Epigenomic Mapping of Myelodysplastic Syndrome Reveals a High Level of Functionally Important Methylation.

A High Resolution Epigenomic Map of Myelofibrosis Reveals Multiple Chromosomal Deletions and Amplifications Accompanied by a High Level of Functionally Important Methylation.

Sensitivity of Diffuse Large B-Cell Lymphomas to DNA Methyltransferase Inhibitors Is Associated with a Specific Epigenetic Signature.

Meta-Transcriptome of Bone Marrow Stem Cells Demonstrates Platform and Lab Dependant Variability in Gene Expression and Reveals a Novel Set of Enriched Genes.

Lack of Increased Gene Promoter Methylation at Relapse in Acute Promyelocytic Leukemia (APL).

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American Society of Hematology

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American Society of Hematology

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