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Joanna B. Opalinska
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Journal Articles

Deep and Durable Responses in Patients (Pts) with Relapsed/Refractory Multiple Myeloma (MM) Treated with Monotherapy GSK2857916, an Antibody Drug Conjugate Against B-Cell Maturation Antigen (BCMA): Preliminary Results from Part 2 of Study BMA117159

Suzanne Trudel, MD FRCP(C), Nikoletta Lendvai, MD PhD, Rakesh Popat, MD PhD, Peter M. Voorhees, MD, Brandi Reeves, MD, Edward N. Libby, III, MD, Paul G Richardson, MD, Larry Anderson, MD PhD, Heather Sutherland, MD, Kwee Yong, PhD, Axel Hoos, MD PhD, Michele Gorczyca, MS, Soumi Lahiri, PhD, Zangdong He, PhD, Roxanne C Jewell, PhD, Joanna B. Opalinska, MD PhD, Adam D. Cohen, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 741.
https://doi.org/10.1182/blood.V130.Suppl_1.741.741
Published: 2017
Journal Articles

First in Human Study with GSK2857916, an Antibody Drug Conjugated to Microtubule-Disrupting Agent Directed Against B-Cell Maturation Antigen (BCMA) in Patients with Relapsed/Refractory Multiple Myeloma (MM): Results from Study BMA117159 Part 1 Dose Escalation

Adam D. Cohen, MD, Rakesh Popat, Suzanne Trudel, MD, Paul G Richardson, MD, Ed N. Libby, III, MD, Nikoletta Lendvai, MDPhD, Larry D. Anderson, Jr., MD PhD, Heather J. Sutherland, MD PhD, Stephen DeWall, Catherine E Ellis, Zangdong He, Jolly Mazumdar, Catherine Wang, Joanna B. Opalinska, MD PhD, Peter M. Voorhees, MD
Journal: Blood
Blood (2016) 128 (22): 1148.
https://doi.org/10.1182/blood.V128.22.1148.1148
Published: 2016
Journal Articles

The novel AKT inhibitor afuresertib shows favorable safety, pharmacokinetics, and clinical activity in multiple myeloma

Clinical Trials & Observations
Andrew Spencer, Sung-Soo Yoon, Simon J. Harrison, Shannon R. Morris, Deborah A. Smith, Richard A. Brigandi, Jennifer Gauvin, Rakesh Kumar, Joanna B. Opalinska, Christine Chen
Journal: Blood
Blood (2014) 124 (14): 2190–2195.
https://doi.org/10.1182/blood-2014-03-559963
Published: 2014
Includes: Supplemental data
Journal Articles

Novel AKT Inhibitor Afuresertib In Combination With Bortezomib and Dexamethasone Demonstrates Favorable Safety Profile and Significant Clinical Activity In Patients With Relapsed/Refractory Multiple Myeloma

Peter M Voorhees, Andrew Spencer, MD, Heather J. Sutherland, MD, PhD, FRCPC, Michael E O'Dwyer, MD, FRCPI, FRCPath, Shang-Yi Huang, MD, PhD, Keith Stewart, MBA, MB, CHB, Ajai Chari, MD, Michael Rosenzwieg, MD, Ajay K. Nooka, MD, MPH, Cara A Rosenbaum, MD, Craig C Hofmeister, MD, Deborah A Smith, PharmD, Joyce M Antal, Ademi Santiago-Walker, Jennifer Gauvin, Joanna B Opalinska, Suzanne Trudel, MD
Journal: Blood
Blood (2013) 122 (21): 283.
https://doi.org/10.1182/blood.V122.21.283.283
Published: 2013
Journal Articles

Novel AKT Inhibitor GSK2110183 Shows Favorable Safety, Pharmacokinetics, and Clinical Activity in Multiple Myeloma. Preliminary Results From a Phase I First-Time-In-Human Study

Andrew Spencer, MD, Sung-Soo Yoon, Simon J. Harrison, MBBS MRCP (uk) MRCPath (uk) PhD, Shannon Morris, MD, PhD, Deborah Smith, PharmD, Steven J. Freedman, MD, PhD, Richard Brigandi, MD, PhD, Allen Oliff, MD, Joanna B. Opalinska, MD, PhD, Christine Chen, MD
Journal: Blood
Blood (2011) 118 (21): 1856.
https://doi.org/10.1182/blood.V118.21.1856.1856
Published: 2011
Journal Articles

MicroRNA expression in maturing murine megakaryocytes

e-blood
Joanna B. Opalinska, Alexey Bersenev, Zhe Zhang, Alec A. Schmaier, John Choi, Yu Yao, Janine D'Souza, Wei Tong, Mitchell J. Weiss
Journal: Blood
Blood (2010) 116 (23): e128–e138.
https://doi.org/10.1182/blood-2010-06-292920
Published: 2010
Journal Articles

Trisomy 21 enhances human fetal erythro-megakaryocytic development

Brief Report
Stella T. Chou, Joanna B. Opalinska, Yu Yao, Myriam A. Fernandes, Anna Kalota, John S. J. Brooks, John K. Choi, Alan M. Gewirtz, Gwenn-ael Danet-Desnoyers, Richard L. Nemiroff, Mitchell J. Weiss
Journal: Blood
Blood (2008) 112 (12): 4503–4506.
https://doi.org/10.1182/blood-2008-05-157859
Published: 2008
Includes: Supplemental data
Journal Articles

Downregulation of Ribosomal Proteins Is Seen in Non 5q- MDS

Davendra P. Sohal, Andrea Pellagati, Li Zhou, Yongkai Mo, Joanna B. Opalinska, Christina Alencar, Christoph Heuck, Amittha Wickrema, Ellen Friedman, John Greally, Benjamin L. Ebert, Jonathan Warner, Jacqueline Boultwood, Amit Verma
Journal: Blood
Blood (2008) 112 (11): 854.
https://doi.org/10.1182/blood.V112.11.854.854
Published: 2008
Journal Articles

Integrative Genomic Analysis Reveals Aberrant Epigenetic Marks in MDS That Can Be Seen in Peripheral Blood Leucocytes

Li Zhou, Joanna B. Opalinska, Davendra P. Sohal, Yongkai Mo, Suman Kambhampati, Simrit Parmar, Christina Alencar, Christoph Heuck, Ivette Vigoda, Chun Ng, Perry Pahanish, Swati Goel, Carolina Schinke, Lawrence Cytryn, Ellen Friedman, Maria E Figueroa, Amittha Wickrema, PhD, John Greally, Amit Verma
Journal: Blood
Blood (2008) 112 (11): 595.
https://doi.org/10.1182/blood.V112.11.595.595
Published: 2008