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Journal Articles

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar Yu-Hung Leung
Journal: Blood
Blood (2023) 142 (23): 2002–2015.
https://doi.org/10.1182/blood.2023019782
Published: 2023
Journal Articles

Inhibition of Polo-like Kinase 4 Induced Both Cell Intrinsic and Non-Cell Intrinsic Anti-Leukemia Effects on TP53 -Mutated Acute Myeloid Leukemia

Chee Chean Dang, Ka Lam Nelson Ng, Wing Lam, Xiao Yuan Zeng, Li Chuan Zheng, Koon Chuen Chan, Timothy Chi Chun Ng, Tsz Ho Kwok, Wing Yan Leung, Michael Shing Yan Huen, Carmen Chak Lui Wong, Zhi Xun Dou, Tak Wah Mak, Cheuk Him Man, Anskar Yu Hung Leung
Journal: Blood
Blood (2022) 140 (Supplement 1): 3099.
https://doi.org/10.1182/blood-2022-165205
Published: 2022
Journal Articles

Homoharringtonine Overcomes Drug Resistance and Synergises with Venetoclax in Acute Myeloid Leukemia Via Inhibiting Protein Synthesis

Tsz Ho Kwok, Kelvin King Wai Wong, Wing Lam, Chee Chean Dang, Xiaoyuan Zeng, Wing Yan Leung, Timothy Chi Chun Ng, Anskar Leung, Cheuk Him Man
Journal: Blood
Blood (2022) 140 (Supplement 1): 11540.
https://doi.org/10.1182/blood-2022-168364
Published: 2022
Journal Articles

Dysregulation of TGF-Beta Stimulated Smad Signaling Is Seen in Myelodysplasia and Points to the Potential Therapeutic Efficacy of TGF-Beta Receptor I Kinase Inhibition in Low Grade Disease.

Li Zhou, PhD, Christine McMahon, MD, Tushar Bhagat, Christina Alencar, Yiting Yu, M. Fazzari, Davendra P. Sohal, MD, MPH, Krishna Gundabolu, MBBS, MD, Chun Ng, Yongkai Mo, MD, PhD, Amittha Wickrema, PhD, G. Kong, Ellen Friedman, MD, Lubomir Sokol, MD, PhD, Pearlie K Burnette, Ulrich Steidl, MD, PhD, L. Yan, Jm Yingling, MM Lahn, Alan F List, MD, Markus Bitzer, Amit Verma, MD
Journal: Blood
Blood (2009) 114 (22): 737.
https://doi.org/10.1182/blood.V114.22.737.737
Published: 2009
Journal Articles

Integrative Genomic Analysis Reveals Aberrant Epigenetic Marks in MDS That Can Be Seen in Peripheral Blood Leucocytes

Li Zhou, Joanna B. Opalinska, Davendra P. Sohal, Yongkai Mo, Suman Kambhampati, Simrit Parmar, Christina Alencar, Christoph Heuck, Ivette Vigoda, Chun Ng, Perry Pahanish, Swati Goel, Carolina Schinke, Lawrence Cytryn, Ellen Friedman, Maria E Figueroa, Amittha Wickrema, PhD, John Greally, Amit Verma
Journal: Blood
Blood (2008) 112 (11): 595.
https://doi.org/10.1182/blood.V112.11.595.595
Published: 2008