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Journal Articles

Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient β-catenin/Hoxa9/Prmt1 axis

Jennifer Lynch, Estelle Troadec, Tsz Kan Fung, Kornelia Gladysz, Clemence Virely, Priscilla Nga Ieng Lau, Ngai Cheung, Bernd Zeisig, Jason W. H. Wong, Massimo Lopes, Suming Huang, Chi Wai Eric So

Blood (2024) 143 (16): 1586–1598.

https://doi.org/10.1182/blood.2023022082

Published: 2024

Includes: Supplemental data

Journal Articles

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar Yu-Hung Leung

Blood (2023) 142 (23): 2002–2015.

https://doi.org/10.1182/blood.2023019782

Published: 2023

Journal Articles

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Huacheng Luo, Ganqian Zhu, PhD, Tsz Kan Fung, Yi Qiu, PhD, Mingjiang Xu, MD PhD, Chi Wai Eric So, Suming Huang, PhD

Blood (2019) 134 (Supplement_1): 277.

https://doi.org/10.1182/blood-2019-127323

Published: 2019

Journal Articles

Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34 -/Lo MLL-Rearranged Leukemia

Tsz Kan Fung, Bernd Zeisig, Magdalena Zarowiecki, Huacheng Luo, Chiou Tsun Tsai, Boban Stanojevic, Claire Lynn, Anskar Y.-H. Leung, MD PhD, Jan Zuna, Marketa Zaliova, MD PhD, Martin Bornhaeuser, MD, Malte Von Bonin, Boris Lenhard, Suming Huang, PhD, Ghulam J. Mufti, Chi Wai Eric So

Blood (2019) 134 (Supplement_1): 3203.

https://doi.org/10.1182/blood-2019-125078

Published: 2019

Journal Articles

Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia

Cheuk Him Man, Tsz Kan Fung, Haixia Wan, Chae Yin Cher, August Fan, Nelson Ng, Christa Ho, Thomas S. K. Wan, Toshiyuki Tanaka, Chi Wai Eric So, Yok Lam Kwong, Anskar Y. H. Leung

Blood (2015) 125 (25): 3928–3936.

https://doi.org/10.1182/blood-2014-06-580993

Published: 2015

Includes: Supplemental data

Journal Articles

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia

Bai-Liang He, Xiangguo Shi, Cheuk Him Man, Alvin C. H. Ma, Stephen C. Ekker, Howard C. H. Chow, Chi Wai Eric So, William W. L. Choi, Wenqing Zhang, Yiyue Zhang, Anskar Y. H. Leung

Blood (2014) 123 (16): 2518–2529.

https://doi.org/10.1182/blood-2013-02-486688

Published: 2014

Includes: Multimedia, Supplemental data

Journal Articles

Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

Eva Moravcsik, Melanie Joannides, Edwige Voisset, Eva Wessel Stratford, Bernd B. Zeisig, Jo Morris, Ruth Densham, Chris Palgrave, Gordon Stamp, Emma Nye, Robert K. Hills, Paolo Salomoni, Chi Wai Eric So, PHD, Scott C. Kogan, Ellen Solomon, David Grimwade, MD, PhD

Blood (2013) 122 (21): 3721.

https://doi.org/10.1182/blood.V122.21.3721.3721

Published: 2013

Journal Articles

Functional Dissection and Targeting Of Bmi1 Independence Of MN1 Leukemia

Jan-Henrik Mikesch, MD, Maria F Arteaga, PHD, Clemence Virely, PHD, Chi Wai Eric So, PHD

Blood (2013) 122 (21): 474.

https://doi.org/10.1182/blood.V122.21.474.474

Published: 2013

Journal Articles

Discovery of Critical Functions of Histone Demethylase, PHF8, in Mediating ATRA Response in APL

Maria Francisca Arteaga, PhD, Jan-Henrik Mikesch, MD, Chi Wai Eric So, PhD

Blood (2011) 118 (21): 226.

https://doi.org/10.1182/blood.V118.21.226.226

Published: 2011

Journal Articles

Hoxa9 Suppresses Cellular Senescence and Sustains the Development of Leukemic Stem Cells Induced by Fusion Proteins In the Absence of Bmi1.

Lan-Lan Smith, Jenny Yeung, PhD, Bernd B Zeisig, PhD, Ivo Huijbers, PhD, Nik Popov, PhD, Josephine Barnes, PhD, Amanda J Wilson, Sanne Lugthart, PhD, Ruud Delwel, PhD, Jesus Gil, PhD, Maarten van Lohuizen, PhD, Chi Wai Eric So, PhD

Blood (2010) 116 (21): 1578.

https://doi.org/10.1182/blood.V116.21.1578.1578

Published: 2010

Journal Articles

The role of CBFβ in AML1-ETO's activity

Colin Kwok, Bernd B. Zeisig, Shuo Dong, Chi Wai Eric So

Blood (2010) 115 (15): 3176–3177.

https://doi.org/10.1182/blood-2009-12-260570

Published: 2010

Includes: Supplemental data

Journal Articles

Leukemic transformation by the APL fusion protein PRKAR1A-RARα critically depends on recruitment of RXRα

Jihui J. Qiu, Xiaoxi Lu, Bernd B. Zeisig, Zhigui Ma, Xun Cai, Saijuan Chen, Hinrich Gronemeyer, David J. Tweardy, Chi Wai Eric So, Shuo Dong

Blood (2010) 115 (3): 643–652.

https://doi.org/10.1182/blood-2009-07-232652

Published: 2010

Includes: Supplemental data

Journal Articles

Amplification of Histone Methyltransferase, Mixed-Lineage Leukemia (MLL), Perturbs Normal Hematopoiesis and Induces Hematological Disorder.

Bon Ham Yip, Michael A. Caligiuri, M.D., Chi Wai Eric So, PhD

Blood (2009) 114 (22): 1965.

https://doi.org/10.1182/blood.V114.22.1965.1965

Published: 2009

Journal Articles

Transforming Activity of AML1-ETO Oncoprotein Is Independent of CBFβ and ETO but Requires Homo-Oligomeric Interaction.

Bernd B Zeisig, PhD, Colin Kwok, PhD, Jihui Qiu, PhD, Shuo Dong, MD, Chi Wai Eric So, PhD

Blood (2008) 112 (11): 3348.

https://doi.org/10.1182/blood.V112.11.3348.3348

Published: 2008

Journal Articles

Recruitment of RXRα by Homo-Oligomeric RARα Is a Key for RARα-Mediated Transformation.

Bernd B. Zeisig, PhD, Colin Kwok, PhD, Amanda J. Wilson, BSc, Arthur Zelent, PhD, Hinrich Gronemeyer, PhD, Shuo Dong, MD PhD, Chi Wai Eric So, PhD

Blood (2006) 108 (11): 360.

https://doi.org/10.1182/blood.V108.11.360.360

Published: 2006

Journal Articles

Identification of an Oncogenic MLL Fusion Complex with Histone Methylation and Acetylation Activities.

Ngai Cheung, PhD, Judy Yam, Ph.D, Li Chong Chan, Ph.D, Michael L. Cleary, M.D, Chi Wai Eric So, Ph.D

Blood (2006) 108 (11): 732.

https://doi.org/10.1182/blood.V108.11.732.732

Published: 2006

Journal Articles

Disease Models and Transformation Mechanisms Mediated by MLL-AF4 Family Oncoproteins in Human Leukemia.

Chi Wai Eric So, Ph.D., Piu Wong, Min Lin, Ph.D., Michael L. Cleary, M.D.

Blood (2004) 104 (11): 467.

https://doi.org/10.1182/blood.V104.11.467.467

Published: 2004

NARROW

Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient β-catenin/Hoxa9/Prmt1 axis

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34 -/Lo MLL-Rearranged Leukemia

Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia

Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

Functional Dissection and Targeting Of Bmi1 Independence Of MN1 Leukemia

Discovery of Critical Functions of Histone Demethylase, PHF8, in Mediating ATRA Response in APL

Hoxa9 Suppresses Cellular Senescence and Sustains the Development of Leukemic Stem Cells Induced by Fusion Proteins In the Absence of Bmi1.

The role of CBFβ in AML1-ETO's activity

Leukemic transformation by the APL fusion protein PRKAR1A-RARα critically depends on recruitment of RXRα

Amplification of Histone Methyltransferase, Mixed-Lineage Leukemia (MLL), Perturbs Normal Hematopoiesis and Induces Hematological Disorder.

Transforming Activity of AML1-ETO Oncoprotein Is Independent of CBFβ and ETO but Requires Homo-Oligomeric Interaction.

Recruitment of RXRα by Homo-Oligomeric RARα Is a Key for RARα-Mediated Transformation.

Identification of an Oncogenic MLL Fusion Complex with Histone Methylation and Acetylation Activities.

Disease Models and Transformation Mechanisms Mediated by MLL-AF4 Family Oncoproteins in Human Leukemia.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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