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Chi Wai Eric So
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Journal Articles

Hematopoietic stem cell quiescence and DNA replication dynamics maintained by the resilient β-catenin/Hoxa9/Prmt1 axis

Jennifer Lynch, Estelle Troadec, Tsz Kan Fung, Kornelia Gladysz, Clemence Virely, Priscilla Nga Ieng Lau, Ngai Cheung, Bernd Zeisig, Jason W. H. Wong, Massimo Lopes, Suming Huang, Chi Wai Eric So
Journal: Blood
Blood (2024) 143 (16): 1586–1598.
https://doi.org/10.1182/blood.2023022082
Published: 2024
Includes: Supplemental data
Journal Articles

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar Yu-Hung Leung
Journal: Blood
Blood (2023) 142 (23): 2002–2015.
https://doi.org/10.1182/blood.2023019782
Published: 2023
Journal Articles

Hottip Lncrna Reinforces CTCF Defined Chromatin Boundaries and Drives Wnt Target Gene Expression in AML Leukemogenesis

Huacheng Luo, Ganqian Zhu, PhD, Tsz Kan Fung, Yi Qiu, PhD, Mingjiang Xu, MD PhD, Chi Wai Eric So, Suming Huang, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 277.
https://doi.org/10.1182/blood-2019-127323
Published: 2019
Journal Articles

Reconstruction of Human AML Reveals Stem Cell Origin and Therapeutic Targets for Treatment Resistant CD34 -/Lo MLL-Rearranged Leukemia

Tsz Kan Fung, Bernd Zeisig, Magdalena Zarowiecki, Huacheng Luo, Chiou Tsun Tsai, Boban Stanojevic, Claire Lynn, Anskar Y.-H. Leung, MD PhD, Jan Zuna, Marketa Zaliova, MD PhD, Martin Bornhaeuser, MD, Malte Von Bonin, Boris Lenhard, Suming Huang, PhD, Ghulam J. Mufti, Chi Wai Eric So
Journal: Blood
Blood (2019) 134 (Supplement_1): 3203.
https://doi.org/10.1182/blood-2019-125078
Published: 2019
Journal Articles

Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia

Cheuk Him Man, Tsz Kan Fung, Haixia Wan, Chae Yin Cher, August Fan, Nelson Ng, Christa Ho, Thomas S. K. Wan, Toshiyuki Tanaka, Chi Wai Eric So, Yok Lam Kwong, Anskar Y. H. Leung
Journal: Blood
Blood (2015) 125 (25): 3928–3936.
https://doi.org/10.1182/blood-2014-06-580993
Published: 2015
Includes: Supplemental data
Journal Articles

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia

Bai-Liang He, Xiangguo Shi, Cheuk Him Man, Alvin C. H. Ma, Stephen C. Ekker, Howard C. H. Chow, Chi Wai Eric So, William W. L. Choi, Wenqing Zhang, Yiyue Zhang, Anskar Y. H. Leung
Journal: Blood
Blood (2014) 123 (16): 2518–2529.
https://doi.org/10.1182/blood-2013-02-486688
Published: 2014
Includes: Multimedia, Supplemental data
Journal Articles

Disruption Of PML Nuclear Bodies Cooperates In The Pathogenesis Of Acute Promyelocytic Leukemia

Eva Moravcsik, Melanie Joannides, Edwige Voisset, Eva Wessel Stratford, Bernd B. Zeisig, Jo Morris, Ruth Densham, Chris Palgrave, Gordon Stamp, Emma Nye, Robert K. Hills, Paolo Salomoni, Chi Wai Eric So, PHD, Scott C. Kogan, Ellen Solomon, David Grimwade, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 3721.
https://doi.org/10.1182/blood.V122.21.3721.3721
Published: 2013
Journal Articles

Functional Dissection and Targeting Of Bmi1 Independence Of MN1 Leukemia

Jan-Henrik Mikesch, MD, Maria F Arteaga, PHD, Clemence Virely, PHD, Chi Wai Eric So, PHD
Journal: Blood
Blood (2013) 122 (21): 474.
https://doi.org/10.1182/blood.V122.21.474.474
Published: 2013
Journal Articles

Discovery of Critical Functions of Histone Demethylase, PHF8, in Mediating ATRA Response in APL

Maria Francisca Arteaga, PhD, Jan-Henrik Mikesch, MD, Chi Wai Eric So, PhD
Journal: Blood
Blood (2011) 118 (21): 226.
https://doi.org/10.1182/blood.V118.21.226.226
Published: 2011
Journal Articles

Hoxa9 Suppresses Cellular Senescence and Sustains the Development of Leukemic Stem Cells Induced by Fusion Proteins In the Absence of Bmi1.

Lan-Lan Smith, Jenny Yeung, PhD, Bernd B Zeisig, PhD, Ivo Huijbers, PhD, Nik Popov, PhD, Josephine Barnes, PhD, Amanda J Wilson, Sanne Lugthart, PhD, Ruud Delwel, PhD, Jesus Gil, PhD, Maarten van Lohuizen, PhD, Chi Wai Eric So, PhD
Journal: Blood
Blood (2010) 116 (21): 1578.
https://doi.org/10.1182/blood.V116.21.1578.1578
Published: 2010
Journal Articles

The role of CBFβ in AML1-ETO's activity

Colin Kwok, Bernd B. Zeisig, Shuo Dong, Chi Wai Eric So
Journal: Blood
Blood (2010) 115 (15): 3176–3177.
https://doi.org/10.1182/blood-2009-12-260570
Published: 2010
Includes: Supplemental data
Journal Articles

Leukemic transformation by the APL fusion protein PRKAR1A-RARα critically depends on recruitment of RXRα

Jihui J. Qiu, Xiaoxi Lu, Bernd B. Zeisig, Zhigui Ma, Xun Cai, Saijuan Chen, Hinrich Gronemeyer, David J. Tweardy, Chi Wai Eric So, Shuo Dong
Journal: Blood
Blood (2010) 115 (3): 643–652.
https://doi.org/10.1182/blood-2009-07-232652
Published: 2010
Includes: Supplemental data
Journal Articles

Amplification of Histone Methyltransferase, Mixed-Lineage Leukemia (MLL), Perturbs Normal Hematopoiesis and Induces Hematological Disorder.

Bon Ham Yip, Michael A. Caligiuri, M.D., Chi Wai Eric So, PhD
Journal: Blood
Blood (2009) 114 (22): 1965.
https://doi.org/10.1182/blood.V114.22.1965.1965
Published: 2009
Journal Articles

Transforming Activity of AML1-ETO Oncoprotein Is Independent of CBFβ and ETO but Requires Homo-Oligomeric Interaction.

Bernd B Zeisig, PhD, Colin Kwok, PhD, Jihui Qiu, PhD, Shuo Dong, MD, Chi Wai Eric So, PhD
Journal: Blood
Blood (2008) 112 (11): 3348.
https://doi.org/10.1182/blood.V112.11.3348.3348
Published: 2008
Journal Articles

Recruitment of RXRα by Homo-Oligomeric RARα Is a Key for RARα-Mediated Transformation.

Bernd B. Zeisig, PhD, Colin Kwok, PhD, Amanda J. Wilson, BSc, Arthur Zelent, PhD, Hinrich Gronemeyer, PhD, Shuo Dong, MD PhD, Chi Wai Eric So, PhD
Journal: Blood
Blood (2006) 108 (11): 360.
https://doi.org/10.1182/blood.V108.11.360.360
Published: 2006
Journal Articles

Identification of an Oncogenic MLL Fusion Complex with Histone Methylation and Acetylation Activities.

Ngai Cheung, PhD, Judy Yam, Ph.D, Li Chong Chan, Ph.D, Michael L. Cleary, M.D, Chi Wai Eric So, Ph.D
Journal: Blood
Blood (2006) 108 (11): 732.
https://doi.org/10.1182/blood.V108.11.732.732
Published: 2006
Journal Articles

Disease Models and Transformation Mechanisms Mediated by MLL-AF4 Family Oncoproteins in Human Leukemia.

Chi Wai Eric So, Ph.D., Piu Wong, Min Lin, Ph.D., Michael L. Cleary, M.D.
Journal: Blood
Blood (2004) 104 (11): 467.
https://doi.org/10.1182/blood.V104.11.467.467
Published: 2004