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Journal Articles

Tracking Bone Marrow Regeneration after CAR-T Cell Therapy in Myeloma at Spatial Single-Cell Resolution Reveals Determinants of Prolonged Cytopenia

Jennifer Wing Lam Cheung, Prachurjya Panda, Xiang Zhou, Katrin Sinning, Ankit Agrawal, Andy Shing Fung Chan, Johannes Duell, Johannes Waldschmidt, Hermann Einsele, Martin Väth, Andreas Rosenwald, Dominic Grün, Leo Rasche
Journal: Blood
Blood (2024) 144 (Supplement 1): 4639.
https://doi.org/10.1182/blood-2024-203052
Published: 2024
Journal Articles

In Vitro Drug Profiling to Guide Treatment for Relapse/Refractory AML

Stephen Lam, Andrew Chung-Hin Poon, Koon C. Chan, Navrose Kaur Singh, Wing Lam, Ching-Man Wong, Chi Yeung Fung, Wing-Hei Lai, Ka Lam Nelson K. L. Ng, Anskar Y.H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 3603.
https://doi.org/10.1182/blood-2024-209746
Published: 2024
Journal Articles

Inhibition of Threonine Tyrosine Kinase Suppressed TP53- mutated Acute Myeloid Leukaemia Via Synergism with Venetoclax and Activation of the Cgas-Sting Pathway

Wing Lam, Koon C. Chan, Kwui-Wa Tong, Ka-Lam Ng, Mark R Bray, Tak-Wah Mak, Cheuk-Him Man, Anskar Y. H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 1399.
https://doi.org/10.1182/blood-2024-201920
Published: 2024
Journal Articles

Activation of Cgas-Sting Pathway By Hypomethylating Agent in TP53 Mutated MDS/AML

Ka Lam Nelson Ng, Lam Ng, Stephen Lam, Xingliang Liu, Koon C. Chan, Lichuan Zheng, Chunxiao Zhang, Rachel L. S. Tse, Wing Lam, Natalie Nok-Man Chan, Cheuk Him Man, Arthur K.L. Cheung, Ho-Wan Ip, Chun H. Au, Edmond Ma, Chi T. Ng, Ying Ni, Run S. Li, Guang Sheng Ling, Suet Yi Leung, Asif Javed, Anskar Y. H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 2726.
https://doi.org/10.1182/blood-2024-202769
Published: 2024
Journal Articles

Combination of Quizartinib and Omacetaxine Mepesuccinate (QUIZOM) As an Effective Treatment Remodels Proteostasis and Triggers Inflammatory Response in FLT3-ITD AML

Stephen Lam, Li-Chuan Zheng, Kelvin K.W. Wong, Man Kit Garret Leung, Chenqinyao Li, Kwui-Wa Tong, Wing Lam, Xiao-yuan Zheng, Koon C. Chan, Natalie Nok-Man Chan, Ka Lam Nelson K. L. Ng, Chee Chean Dang, Tsz-Ho Kwok, Sze Pui Tsui, Rakesh Sharma, Jason W.H. Wong, Suet Yi Leung, Cheuk-Him Man, Anskar Y.H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 1510.
https://doi.org/10.1182/blood-2024-209860
Published: 2024
Journal Articles

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar Yu-Hung Leung
Journal: Blood
Blood (2023) 142 (23): 2002–2015.
https://doi.org/10.1182/blood.2023019782
Published: 2023
Journal Articles

Homoharringtonine Overcomes Drug Resistance and Synergises with Venetoclax in Acute Myeloid Leukemia Via Inhibiting Protein Synthesis

Tsz Ho Kwok, Kelvin King Wai Wong, Wing Lam, Chee Chean Dang, Xiaoyuan Zeng, Wing Yan Leung, Timothy Chi Chun Ng, Anskar Leung, Cheuk Him Man
Journal: Blood
Blood (2022) 140 (Supplement 1): 11540.
https://doi.org/10.1182/blood-2022-168364
Published: 2022
Journal Articles

Inhibition of Polo-like Kinase 4 Induced Both Cell Intrinsic and Non-Cell Intrinsic Anti-Leukemia Effects on TP53 -Mutated Acute Myeloid Leukemia

Chee Chean Dang, Ka Lam Nelson Ng, Wing Lam, Xiao Yuan Zeng, Li Chuan Zheng, Koon Chuen Chan, Timothy Chi Chun Ng, Tsz Ho Kwok, Wing Yan Leung, Michael Shing Yan Huen, Carmen Chak Lui Wong, Zhi Xun Dou, Tak Wah Mak, Cheuk Him Man, Anskar Yu Hung Leung
Journal: Blood
Blood (2022) 140 (Supplement 1): 3099.
https://doi.org/10.1182/blood-2022-165205
Published: 2022