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Journal Articles

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar Yu-Hung Leung
Journal: Blood
Blood (2023) 142 (23): 2002–2015.
https://doi.org/10.1182/blood.2023019782
Published: 2023
Journal Articles

Homoharringtonine Overcomes Drug Resistance and Synergises with Venetoclax in Acute Myeloid Leukemia Via Inhibiting Protein Synthesis

Tsz Ho Kwok, Kelvin King Wai Wong, Wing Lam, Chee Chean Dang, Xiaoyuan Zeng, Wing Yan Leung, Timothy Chi Chun Ng, Anskar Leung, Cheuk Him Man
Journal: Blood
Blood (2022) 140 (Supplement 1): 11540.
https://doi.org/10.1182/blood-2022-168364
Published: 2022
Journal Articles

Inhibition of Polo-like Kinase 4 Induced Both Cell Intrinsic and Non-Cell Intrinsic Anti-Leukemia Effects on TP53 -Mutated Acute Myeloid Leukemia

Chee Chean Dang, Ka Lam Nelson Ng, Wing Lam, Xiao Yuan Zeng, Li Chuan Zheng, Koon Chuen Chan, Timothy Chi Chun Ng, Tsz Ho Kwok, Wing Yan Leung, Michael Shing Yan Huen, Carmen Chak Lui Wong, Zhi Xun Dou, Tak Wah Mak, Cheuk Him Man, Anskar Yu Hung Leung
Journal: Blood
Blood (2022) 140 (Supplement 1): 3099.
https://doi.org/10.1182/blood-2022-165205
Published: 2022
Journal Articles

A Phase II Single-Arm Open-Labeled Study Evaluating Combination of Quizartinib and Omacetaxine Mepesuccinate (QUIZOM) in Newly Diagnosed or Relapsed/Refractory AML Carrying FlT3-ITD

Chunxiao Zhang, Garret MK Leung, MBBS, Sze Pui Tsui, MSc, Ho-Wan Ip, MBBS,FRCPA, Edmond S. K. Ma, MD, Chun Hang Au, PhD, Chris T.L. Chan, PhD, Ka Lam Nelson Ng, PhD, Sze Fai Yip, MD, Bonnie Kho, MD, Harold K K Lee, MD, Qing LIU, Thomas Wing Yan Leung, Yok Lam Kwong, MD FRCP, Anskar Yu Hung Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3825.
https://doi.org/10.1182/blood-2019-126510
Published: 2019
Journal Articles

Targeting DNA Damage and Repair in Acute Myeloid Leukemia Carrying Internal Tandem Duplication of Fms-like Tyrosine Kinase 3 (FLT3-ITD) - a Mechanistic Study

Ka Lam Nelson Ng, PhD, Claire Lynn, Thomas Wing Yan Leung, Eric Chi Wai So, PhD, Anskar Yu Hung Leung, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1261.
https://doi.org/10.1182/blood-2019-129472
Published: 2019