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Natalie Nok-Man Chan
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Journal Articles

Activation of Cgas-Sting Pathway By Hypomethylating Agent in TP53 Mutated MDS/AML

Ka Lam Nelson Ng, Lam Ng, Stephen Lam, Xingliang Liu, Koon C. Chan, Lichuan Zheng, Chunxiao Zhang, Rachel L. S. Tse, Wing Lam, Natalie Nok-Man Chan, Cheuk Him Man, Arthur K.L. Cheung, Ho-Wan Ip, Chun H. Au, Edmond Ma, Chi T. Ng, Ying Ni, Run S. Li, Guang Sheng Ling, Suet Yi Leung, Asif Javed, Anskar Y. H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 2726.
https://doi.org/10.1182/blood-2024-202769
Published: 2024
Journal Articles

Combination of Quizartinib and Omacetaxine Mepesuccinate (QUIZOM) As an Effective Treatment Remodels Proteostasis and Triggers Inflammatory Response in FLT3-ITD AML

Stephen Lam, Li-Chuan Zheng, Kelvin K.W. Wong, Man Kit Garret Leung, Chenqinyao Li, Kwui-Wa Tong, Wing Lam, Xiao-yuan Zheng, Koon C. Chan, Natalie Nok-Man Chan, Ka Lam Nelson K. L. Ng, Chee Chean Dang, Tsz-Ho Kwok, Sze Pui Tsui, Rakesh Sharma, Jason W.H. Wong, Suet Yi Leung, Cheuk-Him Man, Anskar Y.H. Leung
Journal: Blood
Blood (2024) 144 (Supplement 1): 1510.
https://doi.org/10.1182/blood-2024-209860
Published: 2024
Journal Articles

Inhibition of PLK4 remodels histone methylation and activates the immune response via the cGAS-STING pathway in TP53-mutated AML

Cheuk-Him Man, Wing Lam, Chee-Chean Dang, Xiao-yuan Zeng, Li-Chuan Zheng, Natalie Nok-Man Chan, Ka-Lam Ng, Koon-Chuen Chan, Tsz-Ho Kwok, Timothy Chi-Chun Ng, Wing-Yan Leung, Michael Shing-Yan Huen, Carmen Chak-Lui Wong, Chi Wai Eric So, Zhixun Dou, Susumu Goyama, Mark Robert Bray, Tak Wah Mak, Anskar Yu-Hung Leung
Journal: Blood
Blood (2023) 142 (23): 2002–2015.
https://doi.org/10.1182/blood.2023019782
Published: 2023