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Sanne Lugthart
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Journal Articles

Stability and evolution of individual-level biomarker patterns across repeated vaso-occlusive crises in sickle cell disease

Free
Kim Summers, Orlando Agrippa, Alfonso Portabales, Kunjan Rana, Paul Telfer, Sanne Lugthart
Journal: Blood
Blood (2025) 146 (Supplement 1): 6222.
https://doi.org/10.1182/blood-2025-6222
Published: 2025
Journal Articles

Multi-dimensional adherence patterns in rare haematological conditions: Longitudinal analysis of real-world patient-reported outcomes

Free
Kim Summers, Orlando Agrippa, Andrea Preston, Muna Yusuf, Tushar Singh, Georgina O'Neill, Claire Harrison, Patrick Harrington, Shirley D'Sa, Paul Telfer, Sanne Lugthart
Journal: Blood
Blood (2025) 146 (Supplement 1): 7973.
https://doi.org/10.1182/blood-2025-7973
Published: 2025
Journal Articles

Nemtabrutinib in participants with relapsed or refractory follicular lymphoma: Updated efficacy and safety from cohort g of the phase 2 bellwave-003 study

Free
Wojciech Jurczak, Ana Basquiera, Isabelle Fleury, Sujun Gao, Arpad Illes, Andras Masszi, Antonio Pinto, Sanne Lugthart, Omur Sevindik, Iryna Kriachok, Elizabeth Phillips, Fei Li, Chan Cheah, Yan Xu, Mohammed Z.H. Farooqui, Jing Yang, Fangfang Lv
Journal: Blood
Blood (2025) 146 (Supplement 1): 3570.
https://doi.org/10.1182/blood-2025-3570
Published: 2025
Journal Articles

Chronic Lymphocytic Leukaemia Patient Experiences, Challenges: Insights from AI-Driven Social Media Listening Analysis

Free
Ashley Lai, Kim Summers, Orlando Agrippa, David Ade-Odunlade, Andrea Preston, Sanne Lugthart
Journal: Blood
Blood (2024) 144 (Supplement 1): 7738.
https://doi.org/10.1182/blood-2024-210408
Published: 2024
Journal Articles

Enhanced Artificial Intelligence (AI)-Driven Prediction of Vaso-Occlusive Crises in Sickle Cell Disease: Precision through Advanced Machine-Learning Frameworks and Digital Remote Monitoring

Free
Kim Z Summers, Orlando Agrippa, David Ade-Odunlade, Kofi A. Anie, Paul Telfer, Sanne Lugthart
Journal: Blood
Blood (2024) 144 (Supplement 1): 522.
https://doi.org/10.1182/blood-2024-209961
Published: 2024
Journal Articles

Nemtabrutinib, a Noncovalent Reversible BTK Inhibitor in Relapsed or Refractory Follicular Lymphoma: Results from the Phase 2 Bellwave-003 Study

Free
Wojciech Jurczak, Isabelle Fleury, Antonio Pinto, Sanne Lugthart, Omur Gokmen Sevindik, Iryna Kryachok, Elizabeth Phillips, Fei Li, Chan Y. Cheah, Jing Yang, Yan Xu, Siyang Leng, Fangfang Lv
Journal: Blood
Blood (2024) 144 (Supplement 1): 1634.
https://doi.org/10.1182/blood-2024-201578
Published: 2024
Journal Articles

A Virtual Hospital Approach in Sickle Cell Disease | Remote Biometric, Quality of Life, and Hospitalisations Monitoring

Free
Kim Summers, Orlando Agrippa, Kofi A. Anie, Paul Telfer, Sanne Lugthart
Journal: Blood
Blood (2024) 144 (Supplement 1): 5072.
https://doi.org/10.1182/blood-2024-210919
Published: 2024
Journal Articles

Comparison of Sickle Cell Disease Patient Experiences in Developed and Developing Countries: Insights from UK and India Patient Cohorts

Free
Ashley Lai, Kim Summers, Orlando Agrippa, Kofi A. Anie, Paul Telfer, Sanne Lugthart
Journal: Blood
Blood (2024) 144 (Supplement 1): 5071.
https://doi.org/10.1182/blood-2024-210767
Published: 2024
Journal Articles

Real-World Outcomes and Digitally Monitored Quality of Life in Voxelotor-Treated Patients with Sickle Cell Disease

Free
Kim Summers, Orlando Agrippa, Oliver Shastri, Seraj Sharif, Kofi Anie, Paul Telfer, Sanne Lugthart
Journal: Blood
Blood (2023) 142 (Supplement 1): 2383.
https://doi.org/10.1182/blood-2023-181426
Published: 2023
Journal Articles

Predicting Vaso-Occlusive Crises in Sickle Cell Disease through Digital, Longitudinal Tracking of Wearable Metrics and Patient-Reported Outcomes

Free
Kim Summers, Orlando Agrippa, Sanne Lugthart, Kofi Anie, Paul Telfer
Journal: Blood
Blood (2023) 142 (Supplement 1): 1059.
https://doi.org/10.1182/blood-2023-181407
Published: 2023
Journal Articles

Improvement in Lymphoma CAR-T Outcomes over Time in the UK - CAR-T Learning Curve or Better Bridging?

Free
Stephen Boyle, Robin Sanderson, Maeve A. O'Reilly, Tobias F. Menne, Jane Norman, Adrian Bloor, Sanne Lugthart, Sridhar Chaganti, Carlos Gonzalez-Arias, Ceri Jones, Anne-Louise Latif, Reuben Benjamin, Piers Patten, Deborah Yallop, Victoria Potter, Claire Roddie, Andrea Kuhnl
Journal: Blood
Blood (2022) 140 (Supplement 1): 4649–4651.
https://doi.org/10.1182/blood-2022-159217
Published: 2022
Journal Articles

Treatment with IMR-687, a Highly Selective PDE9 Inhibitor, Increases HbF and Reduces VOCs in Adults with Sickle Cell Disease in a Long-Term, Phase 2a, Open-Label Extension Study

Free
Biree Andemariam, Timothy Mant, Perla Eleftheriou, Sanne Lugthart, Lanetta Bronté-Hall, Filipa Barroso, Gershwin Blyden, James Mason, Constance M Barysauskas, Joseph Yen, Karen Tang, Rahul Ballal, Kenneth Attie
Journal: Blood
Blood (2021) 138 (Supplement 1): 2046.
https://doi.org/10.1182/blood-2021-149536
Published: 2021
Journal Articles

Benefits and Safety of Long-Term Use of IMR-687 As Monotherapy or in Combination with a Stable Dose of Hydroxyurea (HU) in 2 Adult Sickle Cell Patients

Free
Lanetta Bronte-Hall, MD MPH, MSPH, Biree Andemariam, MD, Blyden Gershwin, MD, Sanne Lugthart, MD PhD, Timothy Mant, MB, FFPM, FRCP, Jo Howard, MBBChir, MRCP, FRCPath, Henry Fok, MBBS, PhD, Perla Eleftheriou, FRCPath, MRCP, Robert Ward Hagar, MD, James Mason, DO, Rahul Ballal, PhD, Joelle Lufkin, MPH, Eleanor Lisbon, MD MPH
Journal: Blood
Blood (2020) 136 (Supplement 1): 29–30.
https://doi.org/10.1182/blood-2020-140540
Published: 2020
Journal Articles

Real-World Data of High-Grade Lymphoma Patients Treated with CD19 CAR-T in England

Free
Andrea Kuhnl, Claire Roddie, PhD MD, Nuria Martinez-Cibrian, Tobias F Menne, MD PhD FRCPath, Kim Linton, MBChB PhD, Sanne Lugthart, Sridhar Chaganti, MDPhDMRCP,FRCPath, Robin Sanderson, MRCP,FRCPath, Maria A V Marzolini, Jane Norman, MD, Wendy Osborne, MD, John Radford, Stephen Robinson, MBBS, PhD BSc, Ram Malladi, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Maeve A O'Reilly, MBBCHBAO, Muhammad Saif, MD, Geoff Shenton, Adrian Bloor, FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David A. Irvine, BSc, MBBChir, MRCP, FRCPath, PhD, Orla Stewart, Arzhang Ardavan, Kate Robinson, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Kristian M Bowles, MBBS, PhD, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Rod Johnson, Andrew K McMillan, FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 767.
https://doi.org/10.1182/blood-2019-124177
Published: 2019
Journal Articles

EVI1 is critical for the pathogenesis of a subset of MLL-AF9 –rearranged AMLs

Free
Clinical Trials & Observations
Eric M. J. Bindels, Marije Havermans, Sanne Lugthart, Claudia Erpelinck, Elizabeth Wocjtowicz, Andrei V. Krivtsov, Elwin Rombouts, Scott A. Armstrong, Erdogan Taskesen, Jurgen R. Haanstra, H. Berna Beverloo, Hartmut Döhner, Wendy A. Hudson, John H. Kersey, Ruud Delwel, Ashish R. Kumar
Journal: Blood
Blood (2012) 119 (24): 5838–5849.
https://doi.org/10.1182/blood-2011-11-393827
Published: 2012
Includes: Supplemental data
Journal Articles

An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model

Free
Rachel J. Bergerson, Lara S. Collier, Aaron L. Sarver, Raha A. Been, Sanne Lugthart, Miechaleen D. Diers, Johannes Zuber, Amy R. Rappaport, Molly J. Nixon, Kevin A. T. Silverstein, Danhua Fan, Anne-Francoise J. Lamblin, Linda Wolff, John H. Kersey, Ruud Delwel, Scott W. Lowe, M. Gerard O'Sullivan, Scott C. Kogan, David J. Adams, David A. Largaespada
Journal: Blood
Blood (2012) 119 (19): 4512–4523.
https://doi.org/10.1182/blood-2010-04-281428
Published: 2012
Includes: Supplemental data
Journal Articles

Aberrant DNA hypermethylation signature in acute myeloid leukemia directed by EVI1

Free
Sanne Lugthart, Maria E. Figueroa, Eric Bindels, Lucy Skrabanek, Peter J. M. Valk, Yushan Li, Stefan Meyer, Claudia Erpelinck-Verschueren, John Greally, Bob Löwenberg, Ari Melnick, Ruud Delwel
Journal: Blood
Blood (2011) 117 (1): 234–241.
https://doi.org/10.1182/blood-2010-04-281337
Published: 2011
Includes: Supplemental data
Journal Articles

Hoxa9 Suppresses Cellular Senescence and Sustains the Development of Leukemic Stem Cells Induced by Fusion Proteins In the Absence of Bmi1.

Free
Lan-Lan Smith, Jenny Yeung, PhD, Bernd B Zeisig, PhD, Ivo Huijbers, PhD, Nik Popov, PhD, Josephine Barnes, PhD, Amanda J Wilson, Sanne Lugthart, PhD, Ruud Delwel, PhD, Jesus Gil, PhD, Maarten van Lohuizen, PhD, Chi Wai Eric So, PhD
Journal: Blood
Blood (2010) 116 (21): 1578.
https://doi.org/10.1182/blood.V116.21.1578.1578
Published: 2010
Journal Articles

Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value

Free
Brief Report
Saman Abbas, Sanne Lugthart, François G. Kavelaars, Anita Schelen, Jasper E. Koenders, Annelieke Zeilemaker, Wim J. L. van Putten, Anita W. Rijneveld, Bob Löwenberg, Peter J. M. Valk
Journal: Blood
Blood (2010) 116 (12): 2122–2126.
https://doi.org/10.1182/blood-2009-11-250878
Published: 2010
Includes: Supplemental data
Journal Articles

DNA Methylation Profiling Predicts Clinical Outcomes and Reveals Unique Insights Into the Molecular Complexity of Acute Myeloid Leukemia.

Free
Maria E Figueroa, MD, Sanne Lugthart, MD, Yushan Li, Claudia Erpelinck-Verschueren, Xutao Deng, Paul J. Christos, PhD, Elizabeth Schifano, Jim Booth, Lucy Skrabanek, Fabien Campagne, Madhu Mazumdar, PhD, John Greally, MB, PhD, Peter Valk, Bob Lowenberg, MD, PhD, Ruud Delwel, PhD, Ari Melnick
Journal: Blood
Blood (2009) 114 (22): 707.
https://doi.org/10.1182/blood.V114.22.707.707
Published: 2009