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Journal Articles

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable EVI1-CtBP1/2 Interaction and By Repressing Myeloid Regulator CEBPA

Dorien Pastoors, Marije Havermans, Remco Hoogenboezem, Roger Mulet-Lazaro, Duncan Brian, Leonie Smeenk, Claudia Erpelinck-Verschueren, Stanley van Herk, Bas Wouters, Jeroen A.A. Demmers, Johannes Zuber, Tariq Enver, Richard WJ Groen, Eric Bindels, Ruud Delwel

Blood (2022) 140 (Supplement 1): 83–84.

https://doi.org/10.1182/blood-2022-156994

Published: 2022

Journal Articles

Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Els Mansell, PhD, Valgardur Sigurdsson, PhD, Elitza Deltcheva, PhD, John Brown, PhD, Chela James, PhD, Kenichi Miharada, PhD, Shamit Soneji, PhD, Jonas Larsson, MD PhD, Tariq Enver, PhD

Blood (2019) 134 (Supplement_1): 2480.

https://doi.org/10.1182/blood-2019-124001

Published: 2019

Journal Articles

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

Ifat Geron, PhD, Angela Maria Savino, PhD, Noa Tal, MD PhD, John Brown, PhD, Virginia A Turati, DPhil, Yu Nee Lee, PhD, Chela James, PhD, Avigail Rein Gil, MD, Yehudit Birger, PhD, Inna Muler, Michal Hameiri, PhD, Victoria Marcu-Malina, PhD, Ute Fischer, PhD, Arndt Borkhardt, MD, Ilan M. Kirsch, MD, Arnon Nagler, MD, Tariq Enver, PhD, Shai Izraeli, MD

Blood (2018) 132 (Supplement 1): 566.

https://doi.org/10.1182/blood-2018-99-115913

Published: 2018

Journal Articles

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As a Developmental Susceptibility to ETV6-RUNX1

Simon E Richardson, MA, MD PhD MRCP, FRPATH, Charlotta Boiers, MDPhD, Alya Zriwil, PhD, Emma Laycock, Virginia A Turati, DPhil, John Brown, PhD, Jason Wray, PhD, Chela James, PhD, Dapeng Wang, PhD, Javier Herrero, PhD, Ewa Sitnicka, PhD, Stefan Karlsson, MD, Andrew J.H. Smith, PhD, Sten Eirik Jacobsen, MDPhD, Tariq Enver, PhD

Blood (2017) 130 (Supplement 1): 1218.

https://doi.org/10.1182/blood.V130.Suppl_1.1218.1218

Published: 2017

Journal Articles

Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA

Blood (2017) 129 (23): 3126–3129.

https://doi.org/10.1182/blood-2016-06-721712

Published: 2017

Includes: Supplemental data

Journal Articles

Transgenic Zebrafish Expressing the Human TEL-AML1 Oncogene Have Aberrant Developmental Myelopoiesis

Oscar Pena, Catherine Hockings, MBBChir, MA, FRCPath, MRCP, Gregorio Contento, Jasmine Rowell, Hatem Sabaawy, MD PhD, Tariq Enver, PhD, Elspeth M Payne, MD PhD

Blood (2016) 128 (22): 2711.

https://doi.org/10.1182/blood.V128.22.2711.2711

Published: 2016

Journal Articles

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

Virginia A Turati, PhD, José Afonso Guerra-Assunção, PhD, John C Ambrose, PhD, John Brown, PhD, Mike Hubank, PhD, Alex Hobbs, PhD, Mark Lynch, PhD, Bernadett Gaal, PhD, Sarah Inglott, Lucia Conde, PhD, Simon Richardson, MD PhD, Javier Herrero, PhD, Sten Eirik Jacobsen, MD PhD, Tariq Enver, PhD

Blood (2016) 128 (22): 606.

https://doi.org/10.1182/blood.V128.22.606.606

Published: 2016

Journal Articles

VEGFA- a New Therapeutic Target in CNS Leukemia

Blood (2016) 128 (22): 911.

https://doi.org/10.1182/blood.V128.22.911.911

Published: 2016

Journal Articles

The histone demethylase Jarid1b is required for hematopoietic stem cell self-renewal in mice

Morag H. Stewart, Mareike Albert, Patrycja Sroczynska, V. Adam Cruickshank, Yanping Guo, Derrick J. Rossi, Kristian Helin, Tariq Enver

Blood (2015) 125 (13): 2075–2078.

https://doi.org/10.1182/blood-2014-08-596734

Published: 2015

Includes: Supplemental data

Journal Articles

Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology

Bella Patel, Aditi Dey, Anna Z. Castleton, Claire Schwab, Edward Samuel, Janani Sivakumaran, Brendan Beaton, Nahid Zareian, Christie Yu Zhang, Lena Rai, Tariq Enver, Anthony V. Moorman, Adele K. Fielding

Blood (2014) 124 (1): 96–105.

https://doi.org/10.1182/blood-2014-01-549352

Published: 2014

Includes: Supplemental data

Journal Articles

Network Analysis Of Single Cells Identifies DDIT3 As a Nucleator Of Erythroid Signatures In Early Erythro-Myelopoiesis

Cristina Pina, MD DPhil, Jose Teles, PhD, Cristina Fugazza, PhD, Yanping Guo, DPhil, Gillian May, Ph.D., Carsten Peterson, PhD, Prof., Tariq Enver, Ph.D., Prof.

Blood (2013) 122 (21): 44.

https://doi.org/10.1182/blood.V122.21.44.44

Published: 2013

Journal Articles

Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance

Amelie V. Guitart, Chithra Subramani, Alejandro Armesilla-Diaz, Gillian Smith, Catarina Sepulveda, Deniz Gezer, Milica Vukovic, Karen Dunn, Patrick Pollard, Tessa L. Holyoake, Tariq Enver, Peter J. Ratcliffe, Kamil R. Kranc

Blood (2013) 122 (10): 1741–1745.

https://doi.org/10.1182/blood-2013-02-484923

Published: 2013

Includes: Supplemental data

Journal Articles

Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem and progenitor cells

Christine Karlsson, Aurélie Baudet, Natsumi Miharada, Shamit Soneji, Rajeev Gupta, Mattias Magnusson, Tariq Enver, Göran Karlsson, Jonas Larsson

Blood (2013) 121 (19): 3838–3842.

https://doi.org/10.1182/blood-2013-02-481192

Published: 2013

Includes: Supplemental data

Journal Articles

Gene Regulatory Networks Governing Hematopoietic Stem Cell Development and Identity

Tariq Enver, Ph.D., Prof.

Blood (2011) 118 (21): SCI-30.

https://doi.org/10.1182/blood.V118.21.SCI-30.SCI-30

Published: 2011

Journal Articles

Gata2 Is a Direct Target for Smad-Mediated TGFβ Signaling in Hematopoietic Stem/Progenitor Cells

Matilda Nifelt Hägerström, Emma Rörby, Gillian May, Ph.D., Alex Tipping, Ph.D., John Brown, Ph.D., Göran Karlsson, Ph.D., Tariq Enver, Ph.D., Stefan Karlsson, M.D., Ph.D.

Blood (2011) 118 (21): 1311.

https://doi.org/10.1182/blood.V118.21.1311.1311

Published: 2011

Journal Articles

The Earliest Thymic T Cell Progenitors Sustain B Cell and Myeloid Lineage Potentials

Blood (2011) 118 (21): 2335.

https://doi.org/10.1182/blood.V118.21.2335.2335

Published: 2011

Journal Articles

Human induced pluripotent stem cells are capable of B-cell lymphopoiesis

Lee Carpenter, Ram Malladi, Cheng-Tao Yang, Anna French, Katherine J. Pilkington, Richard W. Forsey, Jackie Sloane-Stanley, Kathryn M. Silk, Timothy J. Davies, Paul J. Fairchild, Tariq Enver, Suzanne M. Watt

Blood (2011) 117 (15): 4008–4011.

https://doi.org/10.1182/blood-2010-08-299941

Published: 2011

Includes: Supplemental data

Journal Articles

Selective Persistence of Distinct Stem/B Leukaemic Stem Cells In Childhood Acute Lymphoblastic Leukaemia In Clinical Remission.

Christoph Lutz, MD, Petter Woll, PhD, Anders Castor, MD, PhD, Helen Ferry, PhD, Christina Jensen, PhD, Joanne Green, Helene Dreau, Michael Lutteropp, Anna Schuh, MD, PhD, Georgina Hall, MD, PhD, Chris Mitchell, MD, PhD, Jan Zuna, MD, PhD, Veronica Buckle, PhD, Sten Eirik W Jacobsen, MD, PhD, Tariq Enver, PhD

Blood (2010) 116 (21): 1585.

https://doi.org/10.1182/blood.V116.21.1585.1585

Published: 2010

Journal Articles

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Blood (2010) 116 (21): 91.

https://doi.org/10.1182/blood.V116.21.91.91

Published: 2010

Journal Articles

Identification of Novel Recurrent Copy Number Variations and Regions of Copy-Neutral Loss of Heterozygosity by High Resolution Genomic Array in Pre-Treatment and Relapsed B-CLL.

Samantha JL Knight, Elham Sadighi Akha, Adele Timbs, Tariq Enver, Andrew R Pettitt, Jenny Taylor, Chris S Hatton, Anna Schuh

Blood (2009) 114 (22): 1098.

https://doi.org/10.1182/blood.V114.22.1098.1098

Published: 2009

NARROW

Oncogene EVI1 Drives Acute Myeloid Leukemia Via a Targetable EVI1-CtBP1/2 Interaction and By Repressing Myeloid Regulator CEBPA

Mitochondrial Activity Identifies a Transcriptionally and Functionally Distinct Subset of Aged HSCs with Lineage-Balanced Output

Activation of CRLF2/IL7RA Signaling in Normal Human Cord Blood Hematopoietic Progenitors Induces Philadelphia-like B-Cell Precursor Pre-Leukemia and Leukemia In Vivo

A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction As a Developmental Susceptibility to ETV6-RUNX1

Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA

Transgenic Zebrafish Expressing the Human TEL-AML1 Oncogene Have Aberrant Developmental Myelopoiesis

Single-Cell Analysis of Clonal Dynamics in Childhood ALL Reveals a Key Role for Transcriptional Intratumor Heterogeneity in Driving Resistance to Chemotherapy

VEGFA- a New Therapeutic Target in CNS Leukemia

The histone demethylase Jarid1b is required for hematopoietic stem cell self-renewal in mice

Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology

Network Analysis Of Single Cells Identifies DDIT3 As a Nucleator Of Erythroid Signatures In Early Erythro-Myelopoiesis

Hif-2α is not essential for cell-autonomous hematopoietic stem cell maintenance

Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem and progenitor cells

Gene Regulatory Networks Governing Hematopoietic Stem Cell Development and Identity

Gata2 Is a Direct Target for Smad-Mediated TGFβ Signaling in Hematopoietic Stem/Progenitor Cells

The Earliest Thymic T Cell Progenitors Sustain B Cell and Myeloid Lineage Potentials

Human induced pluripotent stem cells are capable of B-cell lymphopoiesis

Selective Persistence of Distinct Stem/B Leukaemic Stem Cells In Childhood Acute Lymphoblastic Leukaemia In Clinical Remission.

Co-Existence of LMPP-Like and GMP-Like Leukemia Stem Cells In Acute Myeloid Leukemia

Identification of Novel Recurrent Copy Number Variations and Regions of Copy-Neutral Loss of Heterozygosity by High Resolution Genomic Array in Pre-Treatment and Relapsed B-CLL.

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American Society of Hematology

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ASH Publications

American Society of Hematology

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