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Journal Articles

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

Daniel A. Arber, Attilio Orazi, Robert P. Hasserjian, Michael J. Borowitz, Katherine R. Calvo, Hans-Michael Kvasnicka, Sa A. Wang, Adam Bagg, Tiziano Barbui, Susan Branford, Carlos E. Bueso-Ramos, Jorge E. Cortes, Paola Dal Cin, Courtney D. DiNardo, Hervé Dombret, Eric J. Duncavage, Benjamin L. Ebert, Elihu H. Estey, Fabio Facchetti, Kathryn Foucar, Naseema Gangat, Umberto Gianelli, Lucy A. Godley, Nicola Gökbuget, Jason Gotlib, Eva Hellström-Lindberg, Gabriela S. Hobbs, Ronald Hoffman, Elias J. Jabbour, Jean-Jacques Kiladjian, Richard A. Larson, Michelle M. Le Beau, Mignon L.-C. Loh, Bob Löwenberg, Elizabeth Macintyre, Luca Malcovati, Charles G. Mullighan, Charlotte Niemeyer, Olatoyosi M. Odenike, Seishi Ogawa, Alberto Orfao, Elli Papaemmanuil, Francesco Passamonti, Kimmo Porkka, Ching-Hon Pui, Jerald P. Radich, Andreas Reiter, Maria Rozman, Martina Rudelius, Michael R. Savona, Charles A. Schiffer, Annette Schmitt-Graeff, Akiko Shimamura, Jorge Sierra, Wendy A. Stock, Richard M. Stone, Martin S. Tallman, Jürgen Thiele, Hwei-Fang Tien, Alexandar Tzankov, Alessandro M. Vannucchi, Paresh Vyas, Andrew H. Wei, Olga K. Weinberg, Agnieszka Wierzbowska, Mario Cazzola, Hartmut Döhner, Ayalew Tefferi

Blood (2022) 140 (11): 1200–1228.

https://doi.org/10.1182/blood.2022015850

Published: 2022

Includes: Supplemental data

Journal Articles

Therapy-Related Myeloid Neoplasms in 108 Patients Following Radiation Therapy Only

Anand Ashwin Patel, MD, Alexandra E Rojek, MD, Howard Weiner, Michael W. Drazer, MD, Lucy A. Godley, Michelle M. Le Beau, PhD, Richard A. Larson, MD

Blood (2020) 136 (Supplement 1): 25–26.

https://doi.org/10.1182/blood-2020-134433

Published: 2020

Journal Articles

Creating a Variant Database for the American Society of Hematalogy By Consensus Variant Classification of Common Genes Associated with Hematologic Malignancies

Niroshan Nadarajah, Alex Wagner, PhD, Rafael Bejar, MD PhD, Mark Ewalt, MD, Annette S. Kim, MD, Michelle M. Le Beau, PhD, Xiaotu Ma, PhD, Manja Meggendorfer, PhD, Jamile M. Shammo, MD, Gabriella Ryan, Alexa J. Siddon, MD, David P. Steensma, MD, Matthew J. Walter, MD, Ahmet Zehir, PhD, Jinghui Zhang, PhD, Torsten Haferlach, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-141204

Published: 2020

Journal Articles

RNA:m 5 c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia

Jason Cheng, MD PhD, Li Chen, PhD MD, Yuan Li, MD, Ming Yue, PhD, Adam Cloe, MD, PhD, Jamile M. Shammo, MD FASCP, FACP, Richard A. Larson, MD, Chuan He, PhD, Michelle M. Le Beau, PhD, James W. Vardiman, MD

Blood (2017) 130 (Supplement 1): 2471.

https://doi.org/10.1182/blood.V130.Suppl_1.2471.2471

Published: 2017

Journal Articles

Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apc del/ + MDS mouse model

Angela Stoddart, Jianghong Wang, Chunmei Hu, Anthony A. Fernald, Elizabeth M. Davis, Jason X. Cheng, Michelle M. Le Beau

Blood (2017) 129 (22): 2959–2970.

https://doi.org/10.1182/blood-2016-08-736454

Published: 2017

Includes: Supplemental data

Journal Articles

Inhibition of Canonical WNT Signaling in the Bone Marrow Niche Prevents the Development of Disease in a Mouse MDS Model with Apc Haploinsufficiency

Angela Stoddart, PhD, Jianghong Wang, MD, Chunmei Hu, MD, Anthony A. Fernald, BS, Elizabeth M. Davis, BS, Jason X. Cheng, MDPhD, Michelle M. Le Beau, PhD

Blood (2016) 128 (22): 1129.

https://doi.org/10.1182/blood.V128.22.1129.1129

Published: 2016

Journal Articles

Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex

Li Chen, MD PhD, Yuan Li, MD, Ming Yue, PhD, Adam Cloe, MD PhD, Michelle M. Le Beau, PhD, Chuan He, PhD, Richard A. Larson, MD, James W. Vardiman, MD, Jason X. Cheng, MD PhD

Blood (2016) 128 (22): 746.

https://doi.org/10.1182/blood.V128.22.746.746

Published: 2016

Journal Articles

Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes

Blood (2016) 128 (16): 2096–2097.

https://doi.org/10.1182/blood-2016-07-728766

Published: 2016

Journal Articles

Time-dependent changes in mortality and transformation risk in MDS

Blood (2016) 128 (7): 902–910.

https://doi.org/10.1182/blood-2016-02-700054

Published: 2016

Includes: Supplemental data

Journal Articles

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

Daniel A. Arber, Attilio Orazi, Robert Hasserjian, Jürgen Thiele, Michael J. Borowitz, Michelle M. Le Beau, Clara D. Bloomfield, Mario Cazzola, James W. Vardiman

Blood (2016) 127 (20): 2391–2405.

https://doi.org/10.1182/blood-2016-03-643544

Published: 2016

Includes: Supplemental data

Journal Articles

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

Aparna Vasanthakumar, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Anase Asom, Madison Weatherly, Elizabeth M. Davis, Barbara Neistadt, Robert Duszynski, James W. Vardiman, Michelle M. Le Beau, Lucy A. Godley, Jane E. Churpek

Blood (2016) 127 (3): 310–313.

https://doi.org/10.1182/blood-2015-03-635599

Published: 2016

Includes: Supplemental data

Journal Articles

Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms

Angela Stoddart, Joy Nakitandwe, Shann-Ching Chen, James R. Downing, Michelle M. Le Beau

Blood (2015) 126 (26): 2899–2901.

https://doi.org/10.1182/blood-2015-10-673228

Published: 2015

Journal Articles

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Aparna Vasanthakumar, BSc, MSc, PhD, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Elizabeth M. Davis, BS, Anase Asom, Madison Weatherly, Barbara Neistadt, Robert Duszynski, James W. Vardiman, MD, Michelle M. Le Beau, PhD, Lucy A. Godley, MD PhD, Jane E. Churpek, MD

Blood (2015) 126 (23): 295.

https://doi.org/10.1182/blood.V126.23.295.295

Published: 2015

Journal Articles

Prognostic Impact of Rare Single Abnormalities in Myelodysplastic Syndromes

Blood (2015) 126 (23): 2879.

https://doi.org/10.1182/blood.V126.23.2879.2879

Published: 2015

Journal Articles

Cytotoxic Exposure to Both Hematopoietic Stem and Progenitor Cells and the Bone Marrow Niche Cooperate to Promote Leukemogenesis in a Mouse Model of Therapy-Related Myeloid Neoplasms with a Del(5q)

Angela Stoddart, PhD, Jianghong Wang, MD, Chunmei Hu, MD, Anthony A. Fernald, BS, Elizabeth M. Davis, BS, Jason X. Cheng, MDPhD, Michelle M. Le Beau, PhD

Blood (2015) 126 (23): 357.

https://doi.org/10.1182/blood.V126.23.357.357

Published: 2015

Journal Articles

Targeted Treatment of FLT3 -Overexpressing Acute Myeloid Leukemia with MiR-150 Nanoparticles Guided By Conjugated FLT3 Ligand Peptides

Blood (2015) 126 (23): 3784.

https://doi.org/10.1182/blood.V126.23.3784.3784

Published: 2015

Journal Articles

Overexpression and knockout of miR-126 both promote leukemogenesis

Blood (2015) 126 (17): 2005–2015.

https://doi.org/10.1182/blood-2015-04-639062

Published: 2015

Includes: Supplemental data

Journal Articles

Cellular Reprogramming Erases Aberrant DNA Methylation and the Malignant Phenotype in Chronic Myeloid Leukemia

Giovanni Amabile, PhD, Annalisa Di Ruscio, MDPhD, Fabian Muller, PhD, Robert S Welner, PhD, Henry Yang, PhD, Alexander K Ebralidze, PhD, Hong Zhang, PhD, Lihua Qi, PhD, Giovanni Martinelli, MD, Thijn Brummelkamp, PhD, Michelle M. Le Beau, PhD, Maria E Figueroa, MD, Christoph Bock, PhD, Daniel G Tenen, MD

Blood (2014) 124 (21): 4524.

https://doi.org/10.1182/blood.V124.21.4524.4524

Published: 2014

Journal Articles

Identification of TET1⊣miR-22⊣CREB-MYC Signaling Reveals Potent Tumor-Suppressor Role of Mir-22 in Acute Myeloid Leukemia

Blood (2014) 124 (21): 886.

https://doi.org/10.1182/blood.V124.21.886.886

Published: 2014

Journal Articles

Loss of Wild-Type Kras is Associated with Enhanced Fitness and Increased Mitogen-Activated Protein Kinase Pathway Addiction in K-Ras G12D Acute Myeloid Leukemia

Michael R. Burgess, MD PhD, Eugene Hwang, BA, Anica M. Wandler, PhD, Saurabh Asthana, PhD, Elizabeth M. Davis, BS, Michelle M. Le Beau, PhD, Barry Taylor, PhD, Kevin Shannon, MD

Blood (2014) 124 (21): 907.

https://doi.org/10.1182/blood.V124.21.907.907

Published: 2014

NARROW

International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data

Therapy-Related Myeloid Neoplasms in 108 Patients Following Radiation Therapy Only

Creating a Variant Database for the American Society of Hematalogy By Consensus Variant Classification of Common Genes Associated with Hematologic Malignancies

RNA:m 5 c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia

Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apc del/ + MDS mouse model

Inhibition of Canonical WNT Signaling in the Bone Marrow Niche Prevents the Development of Disease in a Mouse MDS Model with Apc Haploinsufficiency

Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex

Cytopenia levels for aiding establishment of the diagnosis of myelodysplastic syndromes

Time-dependent changes in mortality and transformation risk in MDS

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

Haploinsufficient loss of multiple 5q genes may fine-tune Wnt signaling in del(5q) therapy-related myeloid neoplasms

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Prognostic Impact of Rare Single Abnormalities in Myelodysplastic Syndromes

Cytotoxic Exposure to Both Hematopoietic Stem and Progenitor Cells and the Bone Marrow Niche Cooperate to Promote Leukemogenesis in a Mouse Model of Therapy-Related Myeloid Neoplasms with a Del(5q)

Targeted Treatment of FLT3 -Overexpressing Acute Myeloid Leukemia with MiR-150 Nanoparticles Guided By Conjugated FLT3 Ligand Peptides

Overexpression and knockout of miR-126 both promote leukemogenesis

Cellular Reprogramming Erases Aberrant DNA Methylation and the Malignant Phenotype in Chronic Myeloid Leukemia

Identification of TET1⊣miR-22⊣CREB-MYC Signaling Reveals Potent Tumor-Suppressor Role of Mir-22 in Acute Myeloid Leukemia

Loss of Wild-Type Kras is Associated with Enhanced Fitness and Increased Mitogen-Activated Protein Kinase Pathway Addiction in K-Ras G12D Acute Myeloid Leukemia

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American Society of Hematology

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ASH Publications

American Society of Hematology

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