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Journal Articles

RNA:m 5 c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia

Jason Cheng, MD PhD, Li Chen, PhD MD, Yuan Li, MD, Ming Yue, PhD, Adam Cloe, MD, PhD, Jamile M. Shammo, MD FASCP, FACP, Richard A. Larson, MD, Chuan He, PhD, Michelle M. Le Beau, PhD, James W. Vardiman, MD

Blood (2017) 130 (Supplement 1): 2471.

https://doi.org/10.1182/blood.V130.Suppl_1.2471.2471

Published: 2017

Journal Articles

Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex

Li Chen, MD PhD, Yuan Li, MD, Ming Yue, PhD, Adam Cloe, MD PhD, Michelle M. Le Beau, PhD, Chuan He, PhD, Richard A. Larson, MD, James W. Vardiman, MD, Jason X. Cheng, MD PhD

Blood (2016) 128 (22): 746.

https://doi.org/10.1182/blood.V128.22.746.746

Published: 2016

Journal Articles

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

Daniel A. Arber, Attilio Orazi, Robert Hasserjian, Jürgen Thiele, Michael J. Borowitz, Michelle M. Le Beau, Clara D. Bloomfield, Mario Cazzola, James W. Vardiman

Blood (2016) 127 (20): 2391–2405.

https://doi.org/10.1182/blood-2016-03-643544

Published: 2016

Includes: Supplemental data

Journal Articles

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

Aparna Vasanthakumar, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Anase Asom, Madison Weatherly, Elizabeth M. Davis, Barbara Neistadt, Robert Duszynski, James W. Vardiman, Michelle M. Le Beau, Lucy A. Godley, Jane E. Churpek

Blood (2016) 127 (3): 310–313.

https://doi.org/10.1182/blood-2015-03-635599

Published: 2016

Includes: Supplemental data

Journal Articles

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Aparna Vasanthakumar, BSc, MSc, PhD, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Elizabeth M. Davis, BS, Anase Asom, Madison Weatherly, Barbara Neistadt, Robert Duszynski, James W. Vardiman, MD, Michelle M. Le Beau, PhD, Lucy A. Godley, MD PhD, Jane E. Churpek, MD

Blood (2015) 126 (23): 295.

https://doi.org/10.1182/blood.V126.23.295.295

Published: 2015

Journal Articles

Epigenetic Modifying Drugs Inhibit MDS/AML Cell Growth through Selective Disruption of the Interactions Between Lineage-Determining Transcription Factors and DNA/Histone Modifiers

Yuan Li, MD, Ming Yue, PhD, John Anastasi, MD, Jeffery Q Shen, PhD, Yali Dou, PhD, Richard A. Larson, MD, James W. Vardiman, MD, Jason X. Cheng, MDPhD

Blood (2015) 126 (23): 3853.

https://doi.org/10.1182/blood.V126.23.3853.3853

Published: 2015

Journal Articles

PLZF staining identifies peripheral T-cell lymphomas derived from innate-like T-cells with TRAV1-2-TRAJ33 TCR-α rearrangement

Stephanie McGregor, Anant Shah, Gordana Raca, M. Kamran Mirza, Sonali M. Smith, John Anastasi, James W. Vardiman, Elizabeth Hyjek, Sandeep Gurbuxani

Blood (2014) 123 (17): 2742–2743.

https://doi.org/10.1182/blood-2014-02-555482

Published: 2014

Journal Articles

PLZF Staining Identifies Peripheral T-Cell Lymphomas Derived From Non-Conventional T-Cells With Limited α-Chain Diversity

Stephanie McGregor, MD, PhD, Anant Shah, Gordana Raca, Kamran Mirza, MD PHD, John Anastasi, MD, James W. Vardiman, MD, Elizabeth Hyjek, MD, PhD, Sandeep Gurbuxani, MBBS, PhD

Blood (2013) 122 (21): 4300.

https://doi.org/10.1182/blood.V122.21.4300.4300

Published: 2013

Journal Articles

Disease-Associated Chromatin Conformation and Therapeutic Implications In Leukemia

Jason X Cheng, MD, PhD, John Anastasi, MD, James W. Vardiman, MD

Blood (2013) 122 (21): 4892.

https://doi.org/10.1182/blood.V122.21.4892.4892

Published: 2013

Journal Articles

Clinicopathologic Characterization of Acute Myeloid Leukemia and Myelodysplastic Syndrome with Inv(3)(q21q26.2)/t(3;3)(q21;q26.2) Reveals That Complex Karyotype but Not Blast Percentage Is Associated with Poor Survival; A Bone Marrow Pathology Group Study

Heesun J. Rogers, MD, PhD, James W. Vardiman, MD, John Anastasi, MD, Gordana Raca, MD, PhD, Natasha M Savage, MD, Athena M Cherry, Ph.D., Daniel Arber, MD, Erika Moore, MD, Jennifer JD Morrissette, PhD, Adam Bagg, MD, Yen-Chun Liu, MD, PHD, Susan Mathew, PhD, Attilio Orazi, MD, Pei Lin, MD, Sa A. Wang, MD, Carlos E. Bueso-Ramos, MD, PhD, Kathryn Foucar, MD, Robert P Hasserjian, MD, Eric D. Hsi, MD

Blood (2012) 120 (21): 3847.

https://doi.org/10.1182/blood.V120.21.3847.3847

Published: 2012

Journal Articles

A Novel Epigenetic Mechanism in the Pathogenesis of Myelodysplastic Syndrome (MDS)

Jason X Cheng, MD, PhD, John Anastasi, MD, Jeffery Q Shen, PhD, Kenneth Q Watanabe, Edward Grimley, Erica Kleinbrink, Randal Knibbs, PhD, James W. Vardiman, MD

Blood (2011) 118 (21): 2783.

https://doi.org/10.1182/blood.V118.21.2783.2783

Published: 2011

Journal Articles

P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808

Jonathan E. Kolitz, Stephen L. George, Guido Marcucci, Ravi Vij, Bayard L. Powell, Steven L. Allen, Daniel J. DeAngelo, Thomas C. Shea, Wendy Stock, Maria R. Baer, Vera Hars, Kati Maharry, Eva Hoke, James W. Vardiman, Clara D. Bloomfield, Richard A. Larson, for the Cancer and Leukemia Group B

Blood (2010) 116 (9): 1413–1421.

https://doi.org/10.1182/blood-2009-07-229492

Published: 2010

Journal Articles

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

James W. Vardiman, Jüergen Thiele, Daniel A. Arber, Richard D. Brunning, Michael J. Borowitz, Anna Porwit, Nancy Lee Harris, Michelle M. Le Beau, Eva Hellström-Lindberg, Ayalew Tefferi, Clara D. Bloomfield

Blood (2009) 114 (5): 937–951.

https://doi.org/10.1182/blood-2009-03-209262

Published: 2009

Journal Articles

Pomalidomide Therapy in Anemic Patients with Myelofibrosis: Results from a Phase-2 Randomized Multicenter Study

Ayalew Tefferi, MD, Srdan Verstovsek, Giani Barosi, Francesco Passamonti, MD, Gail J. Roboz, MD, Heinz Gisslinger, Ronald Paquette, MD, Francisco Cervantes, MD, Candido E. Rivera, MD, H. Joachim Deeg, Juergen Thiele, Hans Michael Kvasnicka, James W. Vardiman, MD, B. Nebiyou Bekele, PhD, Ruben A. Mesa, MD, FACP, Robert P Gale, Hagop M Kantarjian

Blood (2008) 112 (11): 663.

https://doi.org/10.1182/blood.V112.11.663.663

Published: 2008

Journal Articles

What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies

Wendy Stock, Mei La, Ben Sanford, Clara D. Bloomfield, James W. Vardiman, Paul Gaynon, Richard A. Larson, James Nachman

Blood (2008) 112 (5): 1646–1654.

https://doi.org/10.1182/blood-2008-01-130237

Published: 2008

Journal Articles

Response: The 2008 World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: a paradigm of effective collaboration among clinicians, pathologists, and scientists

Ayalew Tefferi, Juergen Thiele, James W. Vardiman

Blood (2008) 111 (3): 1742.

https://doi.org/10.1182/blood-2007-11-123364

Published: 2008

Journal Articles

Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia

Blood (2007) 110 (5): 1648–1655.

https://doi.org/10.1182/blood-2007-03-081216

Published: 2007

Includes: Supplemental data

Journal Articles

Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel

Ayalew Tefferi, Juergen Thiele, Attilio Orazi, Hans Michael Kvasnicka, Tiziano Barbui, Curtis A. Hanson, Giovanni Barosi, Srdan Verstovsek, Gunnar Birgegard, Ruben Mesa, John T. Reilly, Heinz Gisslinger, Alessandro M. Vannucchi, Francisco Cervantes, Guido Finazzi, Ronald Hoffman, D. Gary Gilliland, Clara D. Bloomfield, James W. Vardiman

Blood (2007) 110 (4): 1092–1097.

https://doi.org/10.1182/blood-2007-04-083501

Published: 2007

Journal Articles

International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT)

Blood (2006) 108 (5): 1497–1503.

https://doi.org/10.1182/blood-2006-03-009746

Published: 2006

Journal Articles

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

Michael D. Radmacher, Guido Marcucci, Amy S. Ruppert, Krzysztof Mrózek, Susan P. Whitman, James W. Vardiman, Peter Paschka, Tamara Vukosavljevic, Claudia D. Baldus, Jonathan E. Kolitz, Michael A. Caligiuri, Richard A. Larson, Clara D. Bloomfield

Blood (2006) 108 (5): 1677–1683.

https://doi.org/10.1182/blood-2006-02-005538

Published: 2006

Includes: Supplemental data

NARROW

RNA:m 5 c/Methyltransferases Mediate Chromatin Organization and 5-Azacytidine Response/Resistance in Leukemia

Bromodomain and Extra-Terminal Motif Proteins (BETs) Mediate 5-Azacitidine Resistance in Myeloid Leukemia through Recruitment of an Active RNA Polymerase II Complex

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Epigenetic Modifying Drugs Inhibit MDS/AML Cell Growth through Selective Disruption of the Interactions Between Lineage-Determining Transcription Factors and DNA/Histone Modifiers

PLZF staining identifies peripheral T-cell lymphomas derived from innate-like T-cells with TRAV1-2-TRAJ33 TCR-α rearrangement

PLZF Staining Identifies Peripheral T-Cell Lymphomas Derived From Non-Conventional T-Cells With Limited α-Chain Diversity

Disease-Associated Chromatin Conformation and Therapeutic Implications In Leukemia

Clinicopathologic Characterization of Acute Myeloid Leukemia and Myelodysplastic Syndrome with Inv(3)(q21q26.2)/t(3;3)(q21;q26.2) Reveals That Complex Karyotype but Not Blast Percentage Is Associated with Poor Survival; A Bone Marrow Pathology Group Study

A Novel Epigenetic Mechanism in the Pathogenesis of Myelodysplastic Syndrome (MDS)

P-glycoprotein inhibition using valspodar (PSC-833) does not improve outcomes for patients younger than age 60 years with newly diagnosed acute myeloid leukemia: Cancer and Leukemia Group B study 19808

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

Pomalidomide Therapy in Anemic Patients with Myelofibrosis: Results from a Phase-2 Randomized Multicenter Study

What determines the outcomes for adolescents and young adults with acute lymphoblastic leukemia treated on cooperative group protocols? A comparison of Children's Cancer Group and Cancer and Leukemia Group B studies

Response: The 2008 World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: a paradigm of effective collaboration among clinicians, pathologists, and scientists

Distinct patterns of mutations occurring in de novo AML versus AML arising in the setting of severe congenital neutropenia

Proposals and rationale for revision of the World Health Organization diagnostic criteria for polycythemia vera, essential thrombocythemia, and primary myelofibrosis: recommendations from an ad hoc international expert panel

International Working Group (IWG) consensus criteria for treatment response in myelofibrosis with myeloid metaplasia, for the IWG for Myelofibrosis Research and Treatment (IWG-MRT)

Independent confirmation of a prognostic gene-expression signature in adult acute myeloid leukemia with a normal karyotype: a Cancer and Leukemia Group B study

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American Society of Hematology

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American Society of Hematology

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