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Journal Articles

Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apc del/ + MDS mouse model

Angela Stoddart, Jianghong Wang, Chunmei Hu, Anthony A. Fernald, Elizabeth M. Davis, Jason X. Cheng, Michelle M. Le Beau

Blood (2017) 129 (22): 2959–2970.

https://doi.org/10.1182/blood-2016-08-736454

Published: 2017

Includes: Supplemental data

Journal Articles

Inhibition of Canonical WNT Signaling in the Bone Marrow Niche Prevents the Development of Disease in a Mouse MDS Model with Apc Haploinsufficiency

Angela Stoddart, PhD, Jianghong Wang, MD, Chunmei Hu, MD, Anthony A. Fernald, BS, Elizabeth M. Davis, BS, Jason X. Cheng, MDPhD, Michelle M. Le Beau, PhD

Blood (2016) 128 (22): 1129.

https://doi.org/10.1182/blood.V128.22.1129.1129

Published: 2016

Journal Articles

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

Aparna Vasanthakumar, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Anase Asom, Madison Weatherly, Elizabeth M. Davis, Barbara Neistadt, Robert Duszynski, James W. Vardiman, Michelle M. Le Beau, Lucy A. Godley, Jane E. Churpek

Blood (2016) 127 (3): 310–313.

https://doi.org/10.1182/blood-2015-03-635599

Published: 2016

Includes: Supplemental data

Journal Articles

Cytotoxic Exposure to Both Hematopoietic Stem and Progenitor Cells and the Bone Marrow Niche Cooperate to Promote Leukemogenesis in a Mouse Model of Therapy-Related Myeloid Neoplasms with a Del(5q)

Angela Stoddart, PhD, Jianghong Wang, MD, Chunmei Hu, MD, Anthony A. Fernald, BS, Elizabeth M. Davis, BS, Jason X. Cheng, MDPhD, Michelle M. Le Beau, PhD

Blood (2015) 126 (23): 357.

https://doi.org/10.1182/blood.V126.23.357.357

Published: 2015

Journal Articles

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Aparna Vasanthakumar, BSc, MSc, PhD, Stephen Arnovitz, Rafael Marquez, Janet Lepore, George Rafidi, Elizabeth M. Davis, BS, Anase Asom, Madison Weatherly, Barbara Neistadt, Robert Duszynski, James W. Vardiman, MD, Michelle M. Le Beau, PhD, Lucy A. Godley, MD PhD, Jane E. Churpek, MD

Blood (2015) 126 (23): 295.

https://doi.org/10.1182/blood.V126.23.295.295

Published: 2015

Journal Articles

Loss of Wild-Type Kras is Associated with Enhanced Fitness and Increased Mitogen-Activated Protein Kinase Pathway Addiction in K-Ras G12D Acute Myeloid Leukemia

Michael R. Burgess, MD PhD, Eugene Hwang, BA, Anica M. Wandler, PhD, Saurabh Asthana, PhD, Elizabeth M. Davis, BS, Michelle M. Le Beau, PhD, Barry Taylor, PhD, Kevin Shannon, MD

Blood (2014) 124 (21): 907.

https://doi.org/10.1182/blood.V124.21.907.907

Published: 2014

Journal Articles

Haploinsufficiency of del(5q) genes, Egr1 and Apc , cooperate with Tp53 loss to induce acute myeloid leukemia in mice

Angela Stoddart, Anthony A. Fernald, Jianghong Wang, Elizabeth M. Davis, Theodore Karrison, John Anastasi, Michelle M. Le Beau

Blood (2014) 123 (7): 1069–1078.

https://doi.org/10.1182/blood-2013-07-517953

Published: 2014

Includes: Supplemental data

Journal Articles

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc -induced lymphomagenesis

Aparna Vasanthakumar, Janet B. Lepore, Matthew H. Zegarek, Masha Kocherginsky, Mahi Singh, Elizabeth M. Davis, Petra A. Link, John Anastasi, Michelle M. Le Beau, Adam R. Karpf, Lucy A. Godley

Blood (2013) 121 (11): 2059–2063.

https://doi.org/10.1182/blood-2012-04-421065

Published: 2013

Includes: Supplemental data

Journal Articles

Expression of Alternative CALM-AF10 Fusions Causes Different Hematological Malignancies in Mice.

Angela Stoddart, PhD, Anthony A. Fernald, B.Sc., Thelma R. Tennant, Ph.D., Elizabeth M. Davis, B.Sc., John Anastasi, M.D., Michelle M. Le Beau, Ph.D.

Blood (2007) 110 (11): 2640.

https://doi.org/10.1182/blood.V110.11.2640.2640

Published: 2007

Journal Articles

Genomic Rearrangements Associated with -5/del(5q) and -7/del(7q) in Myeloid Leukemias.

Thelma R. Tennant, PhD, Dezheng Huo, PhD, Elizabeth M. Davis, Richard A. Larson, MD, Michelle M. Le Beau, PhD

Blood (2007) 110 (11): 1813.

https://doi.org/10.1182/blood.V110.11.1813.1813

Published: 2007

Journal Articles

Haploinsufficiency of EGR1 , a candidate gene in the del(5q), leads to the development of myeloid disorders

John M. Joslin, Anthony A. Fernald, Thelma R. Tennant, Elizabeth M. Davis, Scott C. Kogan, John Anastasi, John D. Crispino, Michelle M. Le Beau

Blood (2007) 110 (2): 719–726.

https://doi.org/10.1182/blood-2007-01-068809

Published: 2007

Includes: Supplemental data

Journal Articles

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia

Michelle M. Le Beau, Elizabeth M. Davis, Bhumi Patel, Vernon T. Phan, Jastinder Sohal, Scott C. Kogan

Blood (2003) 102 (3): 1072–1074.

https://doi.org/10.1182/blood-2003-01-0155

Published: 2003

Journal Articles

A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657

Jastinder Sohal, Vernon T. Phan, Philip V. Chan, Elizabeth M. Davis, Bhumi Patel, Louise M. Kelly, Tinya J. Abrams, Anne Marie O'Farrell, D. Gary Gilliland, Michelle M. Le Beau, Scott C. Kogan

Blood (2003) 101 (8): 3188–3197.

https://doi.org/10.1182/blood-2002-06-1800

Published: 2003

Journal Articles

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia

Michelle M. Le Beau, Sheila Bitts, Elizabeth M. Davis, Scott C. Kogan

Blood (2002) 99 (8): 2985–2991.

https://doi.org/10.1182/blood.V99.8.2985

Published: 2002

Journal Articles

Heterogeneity in the Breakpoints in Balanced Rearrangements Involving Band 12p13 in Hematologic Malignancies Identified by Fluorescence In Situ Hybridization: TEL ( ETV6 ) Is Involved in Only One Half

Yuko Sato, Stefan K. Bohlander, Hirofumi Kobayashi, Shalini Reshmi, Yoshimasa Suto, Elizabeth M. Davis, Rafael Espinosa, III, Richard Hoopes, Kate T. Montgomery, Raju S. Kucherlapati, Michelle M. Le Beau, Janet D. Rowley

Blood (1997) 90 (12): 4886–4893.

https://doi.org/10.1182/blood.V90.12.4886

Published: 1997

NARROW

Inhibition of WNT signaling in the bone marrow niche prevents the development of MDS in the Apc del/ + MDS mouse model

Inhibition of Canonical WNT Signaling in the Bone Marrow Niche Prevents the Development of Disease in a Mouse MDS Model with Apc Haploinsufficiency

Brca1 deficiency causes bone marrow failure and spontaneous hematologic malignancies in mice

Cytotoxic Exposure to Both Hematopoietic Stem and Progenitor Cells and the Bone Marrow Niche Cooperate to Promote Leukemogenesis in a Mouse Model of Therapy-Related Myeloid Neoplasms with a Del(5q)

Brca1 Deficiency Causes Bone Marrow Failure and Spontaneous Hematologic Malignancies in Mice

Loss of Wild-Type Kras is Associated with Enhanced Fitness and Increased Mitogen-Activated Protein Kinase Pathway Addiction in K-Ras G12D Acute Myeloid Leukemia

Haploinsufficiency of del(5q) genes, Egr1 and Apc , cooperate with Tp53 loss to induce acute myeloid leukemia in mice

Dnmt3b is a haploinsufficient tumor suppressor gene in Myc -induced lymphomagenesis

Expression of Alternative CALM-AF10 Fusions Causes Different Hematological Malignancies in Mice.

Genomic Rearrangements Associated with -5/del(5q) and -7/del(7q) in Myeloid Leukemias.

Haploinsufficiency of EGR1 , a candidate gene in the del(5q), leads to the development of myeloid disorders

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice identify cooperating events and genetic pathways to acute promyelocytic leukemia

A model of APL with FLT3 mutation is responsive to retinoic acid and a receptor tyrosine kinase inhibitor, SU11657

Recurring chromosomal abnormalities in leukemia in PML-RARA transgenic mice parallel human acute promyelocytic leukemia

Heterogeneity in the Breakpoints in Balanced Rearrangements Involving Band 12p13 in Hematologic Malignancies Identified by Fluorescence In Situ Hybridization: TEL ( ETV6 ) Is Involved in Only One Half

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American Society of Hematology

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ASH Publications

American Society of Hematology

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