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Journal Articles

Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo

Julie A.I. Thoms, Feng Yan, Henry R. Hampton, Sarah Davidson, Swapna Joshi, Jesslyn Saw, Chowdhury H. Sarowar, Xin Ying Lim, Andrea C Nunez, Purvi M. Kakadia, Golam Sarower Bhuyan, Xiaoheng Zou, Mary Nguyen, Elaheh S Ghodousi, Forrest C Koch, Fatemeh Vafaee, I. Richard Thompson, Mohammad M. Karimi, Russell Pickford, Mark J Raftery, Sally Hough, Griselda Buckland, Michelle Bailey, Yuvaraj Ghodke, Noorul Absar, Lachlin Vaughan, Leonardo Pasalic, Chun Yew Fong, Melita Kenealy, Devendra Hiwase, Rohanna Stoddart, Soma Mohammed, Linda Lee, Freda H Passam, Stephen Robert Larsen, Kevin J Spring, Kristen K Skarratt, Patricia Rebeiro, Peter Presgrave, William S Stevenson, Silvia Ling, Campbell Tiley, Stephen Fuller, Fernando Roncolato, Anoop K Enjeti, Dirk Hoenemann, Charlotte Lemech, Christopher J Jolly, Stefan K. Bohlander, David J. Curtis, Jason Wong, Ashwin Unnikrishnan, Mark S. Hertzberg, Jake Olivier, Mark N Polizzotto, John E Pimanda

Blood (2024) 144 (Supplement 1): 3223.

https://doi.org/10.1182/blood-2024-201216

Published: 2024

Journal Articles

Signaling Pathway Mutations Cooperate with the PICALM/MLLT10 Fusion in a Knock-in AML Mouse Model

Rhea H. Desai, Peter J. Browett, Purvi M. Kakadia, Stefan K. Bohlander

Blood (2023) 142 (Supplement 1): 4128.

https://doi.org/10.1182/blood-2023-178915

Published: 2023

Journal Articles

Picalm/MLLT10 Expression in Zebrafish Is Associated with an Increase of Hematopoietic Stem Cells and Leads to Leukemia

Omid Delfi, Peter J. Browett, Maryam Saberi, Yih Jian Sung, Purvi M. Kakadia, Stefan K. Bohlander

Blood (2023) 142 (Supplement 1): 5698.

https://doi.org/10.1182/blood-2023-179490

Published: 2023

Journal Articles

Drug Repurposing in a Zebrafish AML Model

Maryam Saberi, Omid Delfi, Peter J. Browett, Purvi M. Kakadia, Stefan K. Bohlander

Blood (2023) 142 (Supplement 1): 5763.

https://doi.org/10.1182/blood-2023-180293

Published: 2023

Journal Articles

Venetoclax Has Potent Efficacy in NPM1 mutated AML with Acquired Resistance Associated with Either Perturbed Pro-Survival Signalling or NPM1 wild-Type Populations

Blood (2023) 142 (Supplement 1): 423.

https://doi.org/10.1182/blood-2023-185321

Published: 2023

Journal Articles

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy

Blood (2023) 141 (11): 1316–1321.

https://doi.org/10.1182/blood.2022018602

Published: 2023

Includes: Supplemental data

Journal Articles

Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment

Blood (2022) 140 (Supplement 1): 9751–9752.

https://doi.org/10.1182/blood-2022-163158

Published: 2022

Journal Articles

In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial

Blood (2022) 140 (Supplement 1): 6927–6929.

https://doi.org/10.1182/blood-2022-157634

Published: 2022

Journal Articles

Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation

James I. Hearn, Taryn N. Green, Colin L. Hisey, Markus Bender, Emma C. Josefsson, Nicholas Knowlton, Juliane Baumann, Raewyn C. Poulsen, Stefan K. Bohlander, Maggie L. Kalev-Zylinska

Blood (2022) 139 (17): 2673–2690.

https://doi.org/10.1182/blood.2021014000

Published: 2022

Includes: Supplemental data

Journal Articles

Clonal Evolution in a Murine CALM-AF10 Leukemia: Evidence of Functional Heterogeneity of Leukemia Stem Cells

Niloofar Zandvakili, Hui Mei Lee, Rhea Desai, Alyona Oryshchuk, Peter J. Browett, Purvi M Kakadia, Stefan K. Bohlander

Blood (2021) 138 (Supplement 1): 1158.

https://doi.org/10.1182/blood-2021-154068

Published: 2021

Journal Articles

MLL/AF9 Expression Causes Leukemia in Zebrafish

Maryam Saberi, Omid Delfi, Dona Wathsala Madola, Peter J. Browett, Purvi M Kakadia, Stefan K. Bohlander

Blood (2021) 138 (Supplement 1): 4330.

https://doi.org/10.1182/blood-2021-154125

Published: 2021

Journal Articles

Characterization of an Acute Myeloid Leukemia Murine Model Driven By MLL/AF9: Effect of Retroviral Insertion Sites and Somatic Mutations on Gene Expression

Hui Mei Lee, Niloofar Zandvakili, Rhea Desai, Peter J. Browett, Purvi M Kakadia, Stefan K. Bohlander

Blood (2021) 138 (Supplement 1): 4329.

https://doi.org/10.1182/blood-2021-154012

Published: 2021

Journal Articles

A Murine Immunocompetent Acute Myeloid Leukemia (AML) Model for Testing Immunotherapies

Hui Mei Lee, Niloofar Zandvakilli, Rhea Desai, PhD, Purvi M Kakadia, PhD, Peter Browett, BMedSci, MBChB, FRACP, FRCPA, Stefan K. Bohlander, MD

Blood (2020) 136 (Supplement 1): 3–4.

https://doi.org/10.1182/blood-2020-141171

Published: 2020

Journal Articles

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

Blood (2020) 136 (15): 1735–1747.

https://doi.org/10.1182/blood.2019001279

Published: 2020

Includes: Supplemental data

Journal Articles

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

Chong Chyn Chua, MBBS, John Reynolds, PhD, Jessica M Salmon, PhD, Chun Fong, Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Ing Soo Tiong, MBBS,FRACP,FRCPA, Shaun Fleming, MBBS,, Sarah MacRaild, Donia M Moujalled, PhD, Giovanna Pomilio, Nik Cummings, Julie McManus, Adam Ivey, BSc, MSc, PhD, Purvi M Kakadia, PhD, Stefan K. Bohlander, MD, Andrew W. Roberts, MBBS, PhD FRACP, FRCPA, Andrew H. Wei, PhD FRACP, FRCPA, MBBS

Blood (2019) 134 (Supplement_1): 462.

https://doi.org/10.1182/blood-2019-126640

Published: 2019

Journal Articles

Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification

Diego Chacon, PhD, Ali Braytee, PhD, Yizhou Huang, PhD, Julie Thoms, PhD, Shruthi Subramanian, BSc, Maria Cristina Sauerland, Stefan K. Bohlander, MD, Jan Braess, MD, Bernhard J. Wörmann, MD, Wolfgang E. Berdel, MD, Wolfgang Hiddemann, MD PhD, Bogdan Gabrys, PhD, Klaus H. Metzeler, MD, Tobias Herold, MD, John Pimanda, MBBS, PhD, Dominik Beck, PhD

Blood (2019) 134 (Supplement_1): 1397.

https://doi.org/10.1182/blood-2019-129519

Published: 2019

Journal Articles

NPM1 Variant Allele Frequency and Outcomes in AML

Blood (2018) 132 (Supplement 1): 1486.

https://doi.org/10.1182/blood-2018-99-112549

Published: 2018

Journal Articles

Genetic or Pharmacological Inhibition of the Polycomb Group Protein BMI1 Impairs Leukemic Transformation Mediated By the CALM-AF10 Fusion Oncoprotein

Karina O. Barbosa, BSc, Anwesha Ghosh, PhD, Anagha Deshpande, PhD, Sayantanee Dutta, PhD, Scott A. Armstrong, MD PhD, Stefan K. Bohlander, MD, Aniruddha J. Deshpande, PhD

Blood (2018) 132 (Supplement 1): 762.

https://doi.org/10.1182/blood-2018-99-115552

Published: 2018

Journal Articles

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Sabrina Opatz, MD, Sebastian Vosberg, Bianka Ksienzyk, Sebastian Tschuri, Alexander Graf, Stefan Krebs, PhD, Helmut Blum, Dr., Stephanie Schneider, PhD, Martin Neumann, Claudia D. Baldus, MD, Christian Thiede, MD, Jan Moritz Middeke, MD, Friedrich Stoelzel, Stefan K. Bohlander, MD, Karsten Spiekermann, MD, Wolfgang Hiddemann, PhD, Klaus H. Metzeler, MD, Philipp A. Greif, MD PD

Blood (2018) 132 (Supplement 1): 2772.

https://doi.org/10.1182/blood-2018-99-115881

Published: 2018

Journal Articles

Molecular Patterns of Response and Outcome in the Chemotherapy and Venetoclax in Elderly AML Trial (CAVEAT study)

Andrew H Wei, MBBS,PhD, Chong Chyn Chua, MBBS, BMedSc, Ing S Tiong, MBChB, Chun Yew Fong, MBBS,FRACP,FRCPA, Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Sarah Macraild, Jessica M Salmon, PhD, Adam Ivey, BSc, MSc, PhD, John Nguyen, Flora Yuen, BBiomedSc, Richard Hall, Shaun Fleming, Stefan K. Bohlander, MD, John Reynolds, PhD, Andrew W. Roberts, MBBS, PhD

Blood (2018) 132 (Supplement 1): 333.

https://doi.org/10.1182/blood-2018-99-114243

Published: 2018

NARROW

Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo

Signaling Pathway Mutations Cooperate with the PICALM/MLLT10 Fusion in a Knock-in AML Mouse Model

Picalm/MLLT10 Expression in Zebrafish Is Associated with an Increase of Hematopoietic Stem Cells and Leads to Leukemia

Drug Repurposing in a Zebrafish AML Model

Venetoclax Has Potent Efficacy in NPM1 mutated AML with Acquired Resistance Associated with Either Perturbed Pro-Survival Signalling or NPM1 wild-Type Populations

Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy

Clinical Response to Azacytidine (AZA) Is Associated with Increased Contribution from Mutated Blood Progenitors: Insights from Single Cell Genotyping of Matched Stem/Progenitor and Mature Blood Cells from MDS/CMML Patients Pre- and Post-AZA Treatment

In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial

Deletion of Grin1 in mouse megakaryocytes reveals NMDA receptor role in platelet function and proplatelet formation

Clonal Evolution in a Murine CALM-AF10 Leukemia: Evidence of Functional Heterogeneity of Leukemia Stem Cells

MLL/AF9 Expression Causes Leukemia in Zebrafish

Characterization of an Acute Myeloid Leukemia Murine Model Driven By MLL/AF9: Effect of Retroviral Insertion Sites and Somatic Mutations on Gene Expression

A Murine Immunocompetent Acute Myeloid Leukemia (AML) Model for Testing Immunotherapies

Lysine acetyltransferase Tip60 is required for hematopoietic stem cell maintenance

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

Prospective Identification of Acute Myeloid Leukemia Patients Who Benefit from Gene-Expression Based Risk Stratification

NPM1 Variant Allele Frequency and Outcomes in AML

Genetic or Pharmacological Inhibition of the Polycomb Group Protein BMI1 Impairs Leukemic Transformation Mediated By the CALM-AF10 Fusion Oncoprotein

Clonal Evolution of Relapsed CBFB/MYH11 Rearranged Acute Myeloid Leukemia (AML)

Molecular Patterns of Response and Outcome in the Chemotherapy and Venetoclax in Elderly AML Trial (CAVEAT study)

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American Society of Hematology

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American Society of Hematology

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