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Jesslyn Saw
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Journal Articles

Clinical Response to Azacitidine in Myelodysplastic Neoplasms Is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor Cells In Vivo

Julie A.I. Thoms, Feng Yan, Henry R. Hampton, Sarah Davidson, Swapna Joshi, Jesslyn Saw, Chowdhury H. Sarowar, Xin Ying Lim, Andrea C Nunez, Purvi M. Kakadia, Golam Sarower Bhuyan, Xiaoheng Zou, Mary Nguyen, Elaheh S Ghodousi, Forrest C Koch, Fatemeh Vafaee, I. Richard Thompson, Mohammad M. Karimi, Russell Pickford, Mark J Raftery, Sally Hough, Griselda Buckland, Michelle Bailey, Yuvaraj Ghodke, Noorul Absar, Lachlin Vaughan, Leonardo Pasalic, Chun Yew Fong, Melita Kenealy, Devendra Hiwase, Rohanna Stoddart, Soma Mohammed, Linda Lee, Freda H Passam, Stephen Robert Larsen, Kevin J Spring, Kristen K Skarratt, Patricia Rebeiro, Peter Presgrave, William S Stevenson, Silvia Ling, Campbell Tiley, Stephen Fuller, Fernando Roncolato, Anoop K Enjeti, Dirk Hoenemann, Charlotte Lemech, Christopher J Jolly, Stefan K. Bohlander, David J. Curtis, Jason Wong, Ashwin Unnikrishnan, Mark S. Hertzberg, Jake Olivier, Mark N Polizzotto, John E Pimanda
Journal: Blood
Blood (2024) 144 (Supplement 1): 3223.
https://doi.org/10.1182/blood-2024-201216
Published: 2024
Journal Articles

STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia

Cedric S. Tremblay, Jesslyn Saw, Jacqueline A. Boyle, Katharina Haigh, Veronique Litalien, Hannah McCalmont, Kathryn Evans, Richard B. Lock, Stephen M. Jane, Jody J. Haigh, David J. Curtis
Journal: Blood
Blood (2023) 142 (3): 274–289.
https://doi.org/10.1182/blood.2022016322
Published: 2023
Includes: Supplemental data
Journal Articles

Non-Linear Trajectories of the Epigenome during T-Cell Leukemogenesis Revealed By Analysis of a Mouse Model of Human ETP-ALL

Feng Yan, Cedric Tremblay, Francine Garret-Bakelman, Jesslyn Saw, Matthew P. McCormack, Shokoufeh Abdollahi, Pieter Van Vlierberghe, David Powell, Nicholas C. Wong, David J. Curtis
Journal: Blood
Blood (2022) 140 (Supplement 1): 5898–5899.
https://doi.org/10.1182/blood-2022-169201
Published: 2022
Journal Articles

Shared roles for Scl and Lyl1 in murine platelet production and function

Sung K. Chiu, Stephanie L. Orive, Mitchell J. Moon, Jesslyn Saw, Sarah Ellis, Benjamin T. Kile, Yizhou Huang, Diego Chacon, John E. Pimanda, Dominik Beck, Justin R. Hamilton, Cedric S. Tremblay, David J. Curtis
Journal: Blood
Blood (2019) 134 (10): 826–835.
https://doi.org/10.1182/blood.2019896175
Published: 2019
Includes: Supplemental data
Journal Articles

Small-Molecule Inhibition of PRMT5 Induces Translational Stress and p53 in JAK2V617F Mutant Myeloproliferative Neoplasms

Stefan Sonderegger, PhD MSc, Loretta Cerruti, BSc, Cedric Tremblay, PhD, Emma Toulmin, PhD, Jesslyn Saw, BSc, Tom Nebl, PhD, Katherine M Hannan, PhD, Steven W. Lane, MD PhD, Hendrik Falk, PhD, Ashwin Unnikrishnan, PhD, Paul Stupple, PhD, Ian Street, PhD, Stephen Jane, MDPhD, Rachel Altura, PhD, Benjamin Nicholson, PhD, David J. Curtis, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 53.
https://doi.org/10.1182/blood-2018-99-118406
Published: 2018
Journal Articles

Either Scl or Lyl1 Is Required to Maintain Primitive Erythropoiesis

Sung Kai Chiu, MBBS, Cedric Tremblay, PhD, Jesslyn Saw, David J. Curtis, MD, PhD
Journal: Blood
Blood (2016) 128 (22): 5057.
https://doi.org/10.1182/blood.V128.22.5057.5057
Published: 2016
Journal Articles

Scl and Lyl1 Are Redundant in Erythropoiesis

Sung Kai Chiu, MBBS, Cedric Tremblay, PhD, Jesslyn Saw, David J. Curtis, MD, PhD
Journal: Blood
Blood (2015) 126 (23): 1182.
https://doi.org/10.1182/blood.V126.23.1182.1182
Published: 2015
Journal Articles

Puma Is The Critical BH3-Only Protein Mediating Apoptosis In The Nup98-HoxD13 (NHD13) Mouse Model Of Human MDS

Andrew Guirguis, MBBS, FRACP, FRCPA, David J. Curtis, M.D., Ph.D., Christopher Slape, PhD, Jesslyn Saw, Andrew H Wei, MBBS, PhD, Laura M Failla, Philippe Bouillet, PhD, Andreas Strasser, PhD
Journal: Blood
Blood (2013) 122 (21): 1563.
https://doi.org/10.1182/blood.V122.21.1563.1563
Published: 2013
Journal Articles

Heterozygous Mutation Of Dynamin 2 Expands The Pool Of IL-7 Responsive Leukemic Stem Cells In T-Cell Acute Lymphoblastic Leukemia

David J. Curtis, M.D., Ph.D., Fiona C. Brown, BSc, Michael Collett, BSc, Sarah E. Lucas, BSc, Jesslyn Saw, Phillip J. Robinson, PhD, Cedric Stevens Tremblay
Journal: Blood
Blood (2013) 122 (21): 613.
https://doi.org/10.1182/blood.V122.21.613.613
Published: 2013
Journal Articles

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

Christopher I. Slape, Jesslyn Saw, Jeremy B. M. Jowett, Peter D. Aplan, Andreas Strasser, Stephen M. Jane, David J. Curtis
Journal: Blood
Blood (2012) 120 (12): 2475–2483.
https://doi.org/10.1182/blood-2012-05-430736
Published: 2012
Includes: Supplemental data
Journal Articles

Dissecting the Mechanism of Apoptosis and Leukemic Transformation In Myelodysplasia

Christopher I Slape, Jesslyn Saw, Laura M Failla, Peter D Aplan, Stephen M Jane, David J Curtis
Journal: Blood
Blood (2010) 116 (21): 610.
https://doi.org/10.1182/blood.V116.21.610.610
Published: 2010