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Veronique Litalien
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Journal Articles

CD74 Antibody Conjugated to an MCL1 Inhibitor (S227928) Combines Synergistically with Venetoclax to Enhance Killing of Acute Myeloid Leukemia

Donia M. Moujalled, Giovanna Pomilio, Thomas Morley, Veronique Litalien, Natasha S. Anstee, Sun Loo, Zhi-Han Yeoh, Clovis Boibessot, Laura Bresson, Ana-Leticia Maragno, Caroline Liot, Andrew H Wei
Journal: Blood
Blood (2024) 144 (Supplement 1): 4136.
https://doi.org/10.1182/blood-2024-202691
Published: 2024
Journal Articles

Co-Targeting BCL-2 and MCL1 (via CDK9) in Pre-Clinical Models of High-Risk Acute Lymphoblastic Leukemia

Donia M. Moujalled, Seong Lin Khaw, Teresa Sadras, Giovanna Pomilio, Thomas Morley, Veronique Litalien, Louise Ludlow, Paul G. Ekert, Diane Hanna
Journal: Blood
Blood (2024) 144 (Supplement 1): 1419.
https://doi.org/10.1182/blood-2024-202757
Published: 2024
Journal Articles

Direct, Potent, and TP53-Independent Activity of Sting Agonists Against Acute Myeloid Leukaemia Enhances Venetoclax Efficacy In Vivo

Yin Yuan, Sarah T Diepstraten, Fiona C. Brown, Veronique Litalien, Andreas Strasser, Gemma L Kelly, Andrew W. Roberts, Andrew H. Wei
Journal: Blood
Blood (2023) 142 (Supplement 1): 4163.
https://doi.org/10.1182/blood-2023-179698
Published: 2023
Journal Articles

STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia

Cedric S. Tremblay, Jesslyn Saw, Jacqueline A. Boyle, Katharina Haigh, Veronique Litalien, Hannah McCalmont, Kathryn Evans, Richard B. Lock, Stephen M. Jane, Jody J. Haigh, David J. Curtis
Journal: Blood
Blood (2023) 142 (3): 274–289.
https://doi.org/10.1182/blood.2022016322
Published: 2023
Includes: Supplemental data
Journal Articles

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Clinical Trials & Observations
Donia M. Moujalled, Fiona C. Brown, Chong Chyn Chua, Michael A. Dengler, Giovanna Pomilio, Natasha S. Anstee, Veronique Litalien, Ella Thompson, Thomas Morley, Sarah MacRaild, Ing S. Tiong, Rhiannon Morris, Karen Dun, Adrian Zordan, Jaynish Shah, Sebastien Banquet, Ensar Halilovic, Erick Morris, Marco J. Herold, Guillaume Lessene, Jerry M. Adams, David C. S. Huang, Andrew W. Roberts, Piers Blombery, Andrew H. Wei
Journal: Blood
Blood (2023) 141 (6): 634–644.
https://doi.org/10.1182/blood.2022016090
Published: 2023
Includes: Supplemental data
Journal Articles

Pharmacological Reduction of Mitochondrial Iron in AML Triggers a BAX/BAK Dependent Non-Canonical Cell Death Synergistic with Venetoclax

Sylvain Garciaz, Sebastian Müller, Andrew Guirguis, Fiona C. Brown, Yih-Chih Chan, Mathilde Poplineau, Kevin Tran, Kah-Lok Chan, Laura MacPherson, Brian Liddicoat, Enid Y. N. Lam, Tatiana Cañeque, Marian L. Burr, Veronique Litalien, Giovanna Pomilio, Estelle Duprez, David C.S. Huang, Sarah-Jane Dawson, Georg Ramm, Andrew G. Cox, Kristin K. Brown, Andrew H. Wei, Kate McArthur, Raphael Rodriguez, Mark A. Dawson
Journal: Blood
Blood (2021) 138 (Supplement 1): 267.
https://doi.org/10.1182/blood-2021-145424
Published: 2021
Journal Articles

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Rachel Thijssen, Sarah T. Diepstraten, Donia Moujalled, Edward Chew, Christoffer Flensburg, Melissa X. Shi, Michael A. Dengler, Veronique Litalien, Sarah MacRaild, Maoshan Chen, Natasha S. Anstee, Boris Reljić, Sarah S. Gabriel, Tirta M. Djajawi, Chris D. Riffkin, Brandon J. Aubrey, Catherine Chang, Lin Tai, Zhen Xu, Thomas Morley, Giovanna Pomilio, Claudia Bruedigam, Axel Kallies, David A. Stroud, Ashish Bajel, Ruth M. Kluck, Steven W. Lane, Marie Schoumacher, Sébastien Banquet, Ian J. Majewski, Andreas Strasser, Andrew W. Roberts, David C. S. Huang, Fiona C. Brown, Gemma L. Kelly, Andrew H. Wei
Journal: Blood
Blood (2021) 137 (20): 2721–2735.
https://doi.org/10.1182/blood.2020010167
Published: 2021
Includes: Supplemental data
Journal Articles

Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Donia M Moujalled, PhD, Fiona C Brown, PhD, Giovanna Pomilio, Natasha S Anstee, PhD, Veronique Litalien, Ella R Thompson, PhD BSc, Thomas Morley, Sarah MacRaild, Chong C Chua, MBBS, BMedSc, SéBastien Banquet, PhD, Maia Chanrion, Ana-Leticia Maragno, PhD, Marie Schoumacher, Marco J Herold, PhD, Guillaume Lessene, PhD, Olivier Geneste, PhD, David C.S. Huang, MBBS MRCP PhD, Andrew W Roberts, MBBS, Piers Blombery, MBBS, Andrew Wei, MBBS,PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-136872
Published: 2020
Journal Articles

Targeting Aurora Kinase B with AZD2811 Enhances Venetoclax Activity in TP53-Mutant AML

Fiona C Brown, Jelena Urosevic, Urszula Polanska, Jan Cosaert, MD PhD, J. Elizabeth Pease, PhD, Giovanna Pomilio, Veronique Litalien, Jon Travers, PhD, Andrew H. Wei
Journal: Blood
Blood (2019) 134 (Supplement_1): 3930.
https://doi.org/10.1182/blood-2019-129564
Published: 2019
Journal Articles

Identification of Potent BH3-Mimetic Combinations Targeting Pro-Survival Pathways in Human B-Cell Acute Lymphoblastic Leukemia

Donia M Moujalled, PhD, Diane T Hanna, Giovanna Pomilio, Veronique Litalien, Shaun Fleming, Marie Chanrion, Ana-Leticia Maragno, Laurence Kraus-Berthier, Seong Lin Khaw, Guillaume Lessene, David Huang, Andrew W. Roberts, MBBS, PhD, Olivier Geneste, Paul G Ekert, Ashley P Ng, Andrew H Wei, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 567.
https://doi.org/10.1182/blood-2018-99-114051
Published: 2018
Journal Articles

Targeting Pre-Leukemic Stem Cells in T-Acute Lymphoblastic Leukemia

Bastien Gerby, PhD, Diogo F.T Veiga, PhD, Jana Krosl, PhD, Julianne Ouellette, André Haman, Geneviève Lavoie, PhD, Iman Fares, MSc, Mathieu Tremblay, PhD, Véronique Litalien, Elizabeth Ottoni, Milena Kosic, Dominique Geoffrion, Joël Ryan, Paul Maddox, PhD, Jalila Chagraoui, PhD, Anne Marinier, PhD, Josée Hébert, MD, Guy Sauvageau, MD, PhD, Benjamin H Kwok, PhD, Philippe P Roux, PhD, Trang Hoang, PhD
Journal: Blood
Blood (2016) 128 (22): 527.
https://doi.org/10.1182/blood.V128.22.527.527
Published: 2016