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Estelle Duprez
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Journal Articles

Deciphering EZH2 Non-Canonical Activities in AML Resistance

Lia N'guyen, Emeline Boet, Camille Montersino, Claire Burny, Stéphane Audebert, Luc Camoin, Rémy Castellano, Sylvain Garciaz, Atsushi Iwama, Jean-Emmanuel Sarry, Estelle Duprez, Mathilde Poplineau
Journal: Blood
Blood (2024) 144 (Supplement 1): 4097.
https://doi.org/10.1182/blood-2024-200580
Published: 2024
Journal Articles

Noncanonical EZH2 drives retinoic acid resistance of variant acute promyelocytic leukemias

Mathilde Poplineau, Nadine Platet, Adrien Mazuel, Léonard Hérault, Lia N’Guyen, Shuhei Koide, Yaeko Nakajima-Takagi, Wakako Kuribayashi, Nadine Carbuccia, Loreen Haboub, Julien Vernerey, Motohiko Oshima, Daniel Birnbaum, Atsushi Iwama, Estelle Duprez
Journal: Blood
Blood (2022) 140 (22): 2358–2370.
https://doi.org/10.1182/blood.2022015668
Published: 2022
Includes: Supplemental data
Journal Articles

Pharmacological Reduction of Mitochondrial Iron in AML Triggers a BAX/BAK Dependent Non-Canonical Cell Death Synergistic with Venetoclax

Sylvain Garciaz, Sebastian Müller, Andrew Guirguis, Fiona C. Brown, Yih-Chih Chan, Mathilde Poplineau, Kevin Tran, Kah-Lok Chan, Laura MacPherson, Brian Liddicoat, Enid Y. N. Lam, Tatiana Cañeque, Marian L. Burr, Veronique Litalien, Giovanna Pomilio, Estelle Duprez, David C.S. Huang, Sarah-Jane Dawson, Georg Ramm, Andrew G. Cox, Kristin K. Brown, Andrew H. Wei, Kate McArthur, Raphael Rodriguez, Mark A. Dawson
Journal: Blood
Blood (2021) 138 (Supplement 1): 267.
https://doi.org/10.1182/blood-2021-145424
Published: 2021
Journal Articles

Single Cell Analyses Reveal a Non-Canonical EZH2 Activity As a Main Driver of Retinoic Acid Resistance in PLZF/Rara Leukemia

Mathilde Poplineau, Nadine Platet, Adrien Mazuel, Léonard Hérault, Shuhei Koide, Wakako Kuribayashi, Nadine Carbuccia, Lia N'Guyen, Julien Vernerey, Motohiko Oshima, Daniel Birnbaum, Christophe Lachaud, Atsushi Iwama, Estelle Duprez
Journal: Blood
Blood (2021) 138 (Supplement 1): 2205.
https://doi.org/10.1182/blood-2021-146777
Published: 2021
Journal Articles

Mining old transcriptomes to predict HSC age

Mathilde Poplineau, Estelle Duprez
Journal: Blood
Blood (2021) 138 (6): 422–423.
https://doi.org/10.1182/blood.2021012002
Published: 2021
Journal Articles

New Insights into PLZF/Rara Mechanism during APL Onset: EZH2 on the Road

Mathilde Poplineau, Nadine Platet, PhD, Lia N'Guyen, Shuhei Koide, PhD, Julien Vernerey, PhD, Yaeko Nakajima-Takagi, PhD, Motohiko Oshima, PhD, Atsushi Iwama, MD PhD, Estelle Duprez, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 3761.
https://doi.org/10.1182/blood-2019-125509
Published: 2019
Journal Articles

PLZF mutation alters mouse hematopoietic stem cell function and cell cycle progression

Brief Report
Christelle Vincent-Fabert, Nadine Platet, Amelle Vandevelde, Mathilde Poplineau, Myriam Koubi, Pascal Finetti, Guillaume Tiberi, Anne-Marie Imbert, François Bertucci, Estelle Duprez
Journal: Blood
Blood (2016) 127 (15): 1881–1885.
https://doi.org/10.1182/blood-2015-09-666974
Published: 2016
Includes: Supplemental data
Journal Articles

Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia

Clinical Trials & Observations
Andrea Kühnl, Peter J. M. Valk, Mathijs A. Sanders, Adam Ivey, Robert K. Hills, Ken I. Mills, Rosemary E. Gale, Martin F. Kaiser, Richard Dillon, Melanie Joannides, Amanda Gilkes, Torsten Haferlach, Susanne Schnittger, Estelle Duprez, David C. Linch, Ruud Delwel, Bob Löwenberg, Claudia D. Baldus, Ellen Solomon, Alan K. Burnett, David Grimwade
Journal: Blood
Blood (2015) 125 (19): 2985–2994.
https://doi.org/10.1182/blood-2014-12-613703
Published: 2015
Includes: Supplemental data
Journal Articles

The IRF2BP2-RARα Fusion Generated By a Cryptic Rearrangement Transforms Hematopoietic Stem/Progenitor Cells and Induces Retinoid Sensitive Acute Promyelocytic Leukemia (APL)

Jelena V Jovanovic, M Carmen Chillón, Christelle Vincent-Fabert, Richard Dillon, Edwige Voisset, Norma C Gutiérrez, Ellen Solomon, Ramón Garcí­a Sanz, Ana A. Martin Lopez, Yvonne G Morgan, Jennie Lok, Estelle Duprez, PhD, Marcos González Díaz, David Grimwade
Journal: Blood
Blood (2014) 124 (21): 2325.
https://doi.org/10.1182/blood.V124.21.2325.2325
Published: 2014
Journal Articles

H3K27me3 Level of the HIST1 Cluster Defines an Epigenetic Marker of Acute Myeloid Leukemia with Prognostic Value

Guillaume Tiberi, Aleksandra Pekowska, PhD, Claire Oudin, MD, Adam Ivey, Thomas Prebet, MD PhD, Myriam Koubi, Frederique Lembo, Marie-Joelle Mozziconacci, MD PhD, Ghislain Bidaut, PhD, Aurelie Autret, B.Sc., Christian Chabannon, MD PhD, David Grimwade, Norbert Vey, MD PhD, Salvatore Spicuglia, PhD, Boris Calmels, PharmD, PhD, Estelle Duprez, PhD
Journal: Blood
Blood (2014) 124 (21): 2326.
https://doi.org/10.1182/blood.V124.21.2326.2326
Published: 2014
Journal Articles

Downregulation Of The Wnt Inhibitor CXXC5 Predicts a Better Prognosis In Acute Myeloid Leukemia

Andrea Kühnl, Peter J. M. Valk, Mathijs A. Sanders, Robert K. Hills, MA, MSc, DPhil, Ken I. Mills, PhD, Rosemary E Gale, PhD, Martin Kaiser, MD, Richard Dillon, Melanie Joannides, Adam Ivey, Amanda F Gilkes, MSc, Torsten Haferlach, MD, Susanne Schnittger, PhD, Estelle Duprez, David Linch, FMedSci, Ruud Delwel, Bob Löwenberg, MD, PhD, Claudia D. Baldus, MD, PhD, Ellen Solomon, Alan K Burnett, MD, David Grimwade, MD, PhD
Journal: Blood
Blood (2013) 122 (21): 52.
https://doi.org/10.1182/blood.V122.21.52.52
Published: 2013
Journal Articles

Defining the Landscape of Resistance Mutations in the Context of Modern Treatment Protocols for Acute Promyelocytic Leukemia (APL).

Jelena V Jovanovic, Fabien Guidez, Farhad Ravandi, Estelle Duprez, Mukunder Patel, Ken Mills, Steven Kornblau, Maadh Aldouri, Martin Auger, Alan K Burnett, Ellen Solomon, David Grimwade
Journal: Blood
Blood (2008) 112 (11): 1492.
https://doi.org/10.1182/blood.V112.11.1492.1492
Published: 2008
Journal Articles

Reduced Binding of C/EBPα to Myeloid Specific Promoters with Altered Gene Expression in the Presence of PML/RARα.

Katharina Wagner, MD, Jürgen Krauter, MD, Kerstin Görlich, Bettina Drescher, PhD, Lisa M. Johansen, PhD, Hanna S. Radomska, PhD, Estelle Duprez, PhD, Arnold Ganser, MD, Daniel G. Tenen, MD
Journal: Blood
Blood (2005) 106 (11): 2999.
https://doi.org/10.1182/blood.V106.11.2999.2999
Published: 2005
Journal Articles

Characterization of Cryptic Rearrangements and Variant Translocations in Acute Promyelocytic Leukemia

David Grimwade, Patricia Gorman, Estelle Duprez, Kathy Howe, Stephen Langabeer, Fiona Oliver, Helen Walker, Dominic Culligan, Jonathan Waters, Mark Pomfret, Anthony Goldstone, Alan Burnett, Paul Freemont, Denise Sheer, Ellen Solomon
Journal: Blood
Blood (1997) 90 (12): 4876–4885.
https://doi.org/10.1182/blood.V90.12.4876
Published: 1997