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Fabien Guidez
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Journal Articles

Immunotherapy with pVAX14 Nucleic Acid in Combination with All-Trans Retinoic Acid (ATRA) in an Acute Promyelocytic Leukemia (APL) Mouse Model Activates Cytotoxic T-Cells and Enhances Immune Responses: A Strategy for Turning “Cold” Tumors “Hot”

Rose Ann Padua, Satyananda Patel, James Smith, Dr Omidvar, Nilgun Tekin, Fabien Guidez, Mathieu Chiquet, Niclas Setterblad, Ken I Mills, Marika PLA, Patricia Krief, Thierry Huet, Christine Chomienne, Pierre Fenaux
Journal: Blood
Blood (2024) 144 (Supplement 1): 4292.
https://doi.org/10.1182/blood-2024-201513
Published: 2024
Journal Articles

Comprehensive Analysis of Mesenchymal Cells from Myeloproliferative Neoplasm (MPN) Patients Reveals the Role of HOXB7 in Myelofibrosis Induction

Saravanan Ganesan, Sarah Awan-Toor, Fabien Guidez, Nabih Maslah, Celine Aoun, Panhong Gou, Chloe Guiguen, Juliette Soret, Odonchimeg Ravdan, Valeria Bisio, Nicolas Dulphy, Marie-Hélène Schlageter, Michele Souyri, Stephane Giraudier, Jean-Jacques Kiladjian, Christine Chomienne, Bruno Cassinat
Journal: Blood
Blood (2022) 140 (Supplement 1): 3852–3854.
https://doi.org/10.1182/blood-2022-157490
Published: 2022
Journal Articles

Benzene-Induced Leukemogenesis: Irreversible Inhibition of PTPN2 and Subsequent STAT1 Signaling Alteration By the Hematotoxic Metabolite Benzoquinone

Romain Duval, Linh-Chi Bui, PhD, Cécile Mathieu, Emile Petit, Jean-Marie Dupret, PhD, Jan Cools, PhD, Fabien Guidez, PhD, Christine Chomienne, MD PhD, Fernando Rodrigues-Lima, PhD
Journal: Blood
Blood (2015) 126 (23): 3671.
https://doi.org/10.1182/blood.V126.23.3671.3671
Published: 2015
Journal Articles

Identification of PLZF-Dmrs in Hematopoiesis Highlight a Novel Role of PLZF As a Guardian of Hematopoietic Genome Integrity

Fabien Guidez, PhD, Laetitia Durand, Technician, Valerie Vidal, William Puszyk, PhD, David Grimwade, Ellen Solomon, Christine Chomienne, MD PhD
Journal: Blood
Blood (2014) 124 (21): 2904.
https://doi.org/10.1182/blood.V124.21.2904.2904
Published: 2014
Journal Articles

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

Rose Ann Padua, PhD, Petra Gorombei, MSc, Stéphanie Beurlet, DMV, PhD, Nader Omidvar, PhD, Satyananda Patel, PhD, Laura Guerenne, MSc, Carole Le Pogam, PhD, Niclas Setterblad, PhD, Pierre de la Grange, PhD, Fabien Guidez, PhD, Christophe Le Boeuf, PhD, Anne Janin, MD PhD, Maria-Elena Noguera, MD, Laure Sarda-Mantel, MD PhD, Pascal Merlet, MD, Robert West, PhD, Marika Pla, PhD, Pierre Fenaux, MD PhD, Patricia Krief, PhD, Christine Chomienne, MD PhD
Journal: Blood
Blood (2014) 124 (21): 3249.
https://doi.org/10.1182/blood.V124.21.3249.3249
Published: 2014
Journal Articles

Defining the Landscape of Resistance Mutations in the Context of Modern Treatment Protocols for Acute Promyelocytic Leukemia (APL).

Jelena V Jovanovic, Fabien Guidez, Farhad Ravandi, Estelle Duprez, Mukunder Patel, Ken Mills, Steven Kornblau, Maadh Aldouri, Martin Auger, Alan K Burnett, Ellen Solomon, David Grimwade
Journal: Blood
Blood (2008) 112 (11): 1492.
https://doi.org/10.1182/blood.V112.11.1492.1492
Published: 2008
Journal Articles

Retinoblastoma Protein and the Leukemia-Associated PLZF Transcription Factor Interact To Repress Target Gene Promoters.

Kevin R. Petrie, PhD, Fabien Guidez, PhD, Jun Zhu, PhD, Gareth Owen, PhD, Yat Peng Chew, Samuel Waxman, MD, Jonathan D. Licht, MD, PhD, Sibylle Mittnacht, PhD, Zelent Arthur, PhD
Journal: Blood
Blood (2007) 110 (11): 1240.
https://doi.org/10.1182/blood.V110.11.1240.1240
Published: 2007
Journal Articles

Physical and Functional Association of PLZF with Histone Methyl Transferase and Histone Demethylase.

Itsaso Hormaeche, Kim Rice, Joti Marango, Fabien Guidez, Arthur Zelent, Jonathan D. Licht
Journal: Blood
Blood (2006) 108 (11): 731.
https://doi.org/10.1182/blood.V108.11.731.731
Published: 2006
Journal Articles

Rexinoid-Triggered Differentiation and Tumor-Selective Apoptosis of AML by Protein Kinase A-Mediated De-Subordination.

Ettore Mariano Schiavone, MD, Lucia Altucci, MD, Mariacarla De Simone, MD, Felicetto Ferrara, MD, Aurélie Rossin, Fellow, Oliver Hirsch, Fellow, Angela Nebbioso, Fellow, Dominique Vitoux, MD, Emmanuelle Wilhelm, Fellow, Fabien Guidez, PhD, Arthur Zelent, MD, David Grimwade, MD, Hugues de Thé, MD, Hinrich Gronemeyer, PhD
Journal: Blood
Blood (2006) 108 (11): 2235.
https://doi.org/10.1182/blood.V108.11.2235.2235
Published: 2006
Journal Articles

Histone Acetyltransferase Activity of p300 Is Required for Transcriptional Repression by the Promyelocytic Leukemia Zinc Finger Protein.

Fabien Guidez, PhD, Louise Howell, BSc, Mark Isalan, PhD, Marek Cebrat, PhD, Rhoda M. Alani, PhD, Sarah Ivins, PhD, Sarah Pierce, PhD, Philip A. Cole, MD, PhD, Jonathan D. Licht, PhD, Arthur Zelent, PhD
Journal: Blood
Blood (2004) 104 (11): 359.
https://doi.org/10.1182/blood.V104.11.359.359
Published: 2004
Journal Articles

Recruitment of the nuclear receptor corepressor N-CoR by the TEL moiety of the childhood leukemia–associated TEL-AML1 oncoprotein

Fabien Guidez, Kevin Petrie, Anthony M. Ford, Huafeng Lu, Caroline A. Bennett, Angus MacGregor, Jürgen Hannemann, Yoshiaki Ito, Jacques Ghysdael, Mel Greaves, Leanne M. Wiedemann, Arthur Zelent
Journal: Blood
Blood (2000) 96 (7): 2557–2561.
https://doi.org/10.1182/blood.V96.7.2557
Published: 2000
Journal Articles

Reduced Retinoic Acid-Sensitivities of Nuclear Receptor Corepressor Binding to PML- and PLZF-RARα Underlie Molecular Pathogenesis and Treatment of Acute Promyelocytic Leukemia

Fabien Guidez, Sarah Ivins, Jun Zhu, Mats Söderström, Samuel Waxman, Arthur Zelent
Journal: Blood
Blood (1998) 91 (8): 2634–2642.
https://doi.org/10.1182/blood.V91.8.2634.2634_2634_2642
Published: 1998