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Journal Articles

Immunotherapy with pVAX14 Nucleic Acid in Combination with All-Trans Retinoic Acid (ATRA) in an Acute Promyelocytic Leukemia (APL) Mouse Model Activates Cytotoxic T-Cells and Enhances Immune Responses: A Strategy for Turning “Cold” Tumors “Hot”

Rose Ann Padua, Satyananda Patel, James Smith, Dr Omidvar, Nilgun Tekin, Fabien Guidez, Mathieu Chiquet, Niclas Setterblad, Ken I Mills, Marika PLA, Patricia Krief, Thierry Huet, Christine Chomienne, Pierre Fenaux

Blood (2024) 144 (Supplement 1): 4292.

https://doi.org/10.1182/blood-2024-201513

Published: 2024

Journal Articles

CXCR4 Drives Lympho-Myeloid Fate of Hematopoietic Progenitors Via mTOR and Mitochondrial Metabolic Pathways

Blood (2021) 138 (Supplement 1): 2150.

https://doi.org/10.1182/blood-2021-149312

Published: 2021

Journal Articles

Hematologic disorder–associated Cxcr4 gain-of-function mutation leads to uncontrolled extrafollicular immune response

Nagham Alouche, Amélie Bonaud, Vincent Rondeau, Rim Hussein-Agha, Julie Nguyen, Valeria Bisio, Mélanie Khamyath, Etienne Crickx, Niclas Setterblad, Nicolas Dulphy, Matthieu Mahevas, David H. McDermott, Philip M. Murphy, Karl Balabanian, Marion Espéli

Blood (2021) 137 (22): 3050–3063.

https://doi.org/10.1182/blood.2020007450

Published: 2021

Includes: Supplemental data

Journal Articles

BCL-2 Inhibitor Venetoclax (ABT-199) and MEK Inhibitor GDC-0973 Synergise to Target AML Progenitors and Overcome Drug Resistance with the Use of PET Scanning in a Mouse Model of HR-MDS to Monitor Response to Treatment

Rose Ann Padua, PhD, Laure Sarda-Mantel, MD PhD, Mathieu Chiquet, BSc, Claire Kappel, BSc, Patricia Krief, PhD, Niclas Setterblad, PhD, Fortune Hontonnou, BSc, Benoit Hosten, PhD, Nicolas Vignal, BSc, Fabien Zassadowski, PhD, Bruno Cassinat, PharmD, PhD, Panhong Gou, BSc, Stephane Giraudier, MD PhD, Marina Y. Konopleva, MD PhD, Michael Andreeff, MD PhD, Marika PLA, PhD, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD, Christine Chomienne, MD PhD

Blood (2018) 132 (Supplement 1): 5497.

https://doi.org/10.1182/blood-2018-99-114212

Published: 2018

Journal Articles

BCL-2 Inhibition with ABT-199 Shows Efficacy in AML Cell Lines with Synergistic Effects upon Addition of the MEK Inhibitor GDC-0973 and Prolongs Survival in an NAS/BCL-2-Mediated Mouse Model of AML Post-MDS

Rose Ann Padua, PhD, Mathieu Chiquet, BSc, Qi Zhang, PhD MD, Claire Kappel, Patricia Krief, PhD, Niclas Setterblad, PhD, Dr Omidvar, BSc, MSc, PhD, Marina Konopleva, MD PhD, Michael Andreeff, MD PhD, Marika PLA, PhD, Lionel Ades, MD PhD, Pierre Fenaux, MD PhD, Christine Chomienne, MD PhD

Blood (2017) 130 (Supplement 1): 2613.

https://doi.org/10.1182/blood.V130.Suppl_1.2613.2613

Published: 2017

Journal Articles

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

Blood (2014) 124 (21): 3249.

https://doi.org/10.1182/blood.V124.21.3249.3249

Published: 2014

Journal Articles

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Blood (2013) 122 (16): 2864–2876.

https://doi.org/10.1182/blood-2012-07-445635

Published: 2013

Includes: Supplemental data

Journal Articles

NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

Blood (2012) 120 (21): 3835.

https://doi.org/10.1182/blood.V120.21.3835.3835

Published: 2012

Journal Articles

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

Youmna Kfoury, Niclas Setterblad, Marwan El-Sabban, Alessia Zamborlini, Zeina Dassouki, Hiba El Hajj, Olivier Hermine, Claudine Pique, Hugues de Thé, Ali Saïb, Ali Bazarbachi

Blood (2011) 117 (1): 190–199.

https://doi.org/10.1182/blood-2010-05-285742

Published: 2011

Includes: Supplemental data

Journal Articles

ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia

Nader Omidvar, Stephanie Beurlet, Carole Le Pogam, Anne Janin, Christophe Leboeuf, Annie Soulie, Niclas Setterblad, Maria-Elena Noguera, Laure Sarda-Mantel, Pascal Merlet, Marika Pla, Scott C. Kogan, MD, Irving L Weissman, Marina Konopleva, William Bormann, Michael Andreeff, Christine Chomienne, Rose Ann Padua

Blood (2008) 112 (11): 848.

https://doi.org/10.1182/blood.V112.11.848.848

Published: 2008

Journal Articles

MHC class II/CD38/CD9: a lipid-raft–dependent signaling complex in human monocytes

Marie-Thérèse Zilber, Niclas Setterblad, Thierry Vasselon, Christelle Doliger, Dominique Charron, Nuala Mooney, Catherine Gelin

Blood (2005) 106 (9): 3074–3081.

https://doi.org/10.1182/blood-2004-10-4094

Published: 2005

Journal Articles

Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria -transformed B lymphocytes

Martin Baumgartner, Pavla Angelisová, Niclas Setterblad, Nuala Mooney, Dirk Werling, Václav Horejsı́, Gordon Langsley

Blood (2003) 101 (5): 1874–1881.

https://doi.org/10.1182/blood-2002-02-0456

Published: 2003

NARROW

Immunotherapy with pVAX14 Nucleic Acid in Combination with All-Trans Retinoic Acid (ATRA) in an Acute Promyelocytic Leukemia (APL) Mouse Model Activates Cytotoxic T-Cells and Enhances Immune Responses: A Strategy for Turning “Cold” Tumors “Hot”

CXCR4 Drives Lympho-Myeloid Fate of Hematopoietic Progenitors Via mTOR and Mitochondrial Metabolic Pathways

Hematologic disorder–associated Cxcr4 gain-of-function mutation leads to uncontrolled extrafollicular immune response

BCL-2 Inhibitor Venetoclax (ABT-199) and MEK Inhibitor GDC-0973 Synergise to Target AML Progenitors and Overcome Drug Resistance with the Use of PET Scanning in a Mouse Model of HR-MDS to Monitor Response to Treatment

BCL-2 Inhibition with ABT-199 Shows Efficacy in AML Cell Lines with Synergistic Effects upon Addition of the MEK Inhibitor GDC-0973 and Prolongs Survival in an NAS/BCL-2-Mediated Mouse Model of AML Post-MDS

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

Tax ubiquitylation and SUMOylation control the dynamic shuttling of Tax and NEMO between Ubc9 nuclear bodies and the centrosome

ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia

MHC class II/CD38/CD9: a lipid-raft–dependent signaling complex in human monocytes

Constitutive exclusion of Csk from Hck-positive membrane microdomains permits Src kinase-dependent proliferation of Theileria -transformed B lymphocytes

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American Society of Hematology

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ASH Publications

American Society of Hematology

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