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Alice C. Fan
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BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Stephanie Beurlet, Nader Omidvar, Petra Gorombei, Patricia Krief, Carole Le Pogam, Niclas Setterblad, Pierre de la Grange, Christophe Leboeuf, Anne Janin, Maria-Elena Noguera, Florence Hervatin, Laure Sarda-Mantel, Marina Konopleva, Michael Andreeff, Andrea W. Tu, Alice C. Fan, Dean W. Felsher, Anthony Whetton, Marika Pla, Robert West, Pierre Fenaux, Christine Chomienne, Rose Ann Padua
Journal: Blood
Blood (2013) 122 (16): 2864–2876.
https://doi.org/10.1182/blood-2012-07-445635
Published: 2013
Includes: Supplemental data
Journal Articles

A Novel Nano-Immunoassay (NIA) Reveals Inhibition of PI3K and MAPK Pathways in CD34+ Bone Marrow Cells of Patients with Myelodysplastic Syndrome (MDS) Treated with the Multi-Kinase Inhibitor On 01910.Na (Rigosertib),

Alice C Fan, MD, Liwen Xu, PhD, Kunju J Sridhar, PhD, Mai Tran, Prajna Banerjee, PhD, John P. Renschler, Radha Tripuraneni, MD, Francois Wilhelm, MD, PhD., Peter L. Greenberg, MD, Dean W. Felsher, MD, PhD
Journal: Blood
Blood (2011) 118 (21): 3808.
https://doi.org/10.1182/blood.V118.21.3808.3808
Published: 2011
Journal Articles

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

Rose Ann Padua, PhD, Stephanie Beurlet, DMV, Patricia Krief, PhD, Nader Omidvar, PhD, Carole Le Pogam, BSc, Didier Auboeuf, PhD, Pierre de la Grange, PhD, Annie Soulie, Anne Janin, MD, PhD, Maria-Elena Noguera, MD, Pascal Merlet, MD, Laure Sarda-Mantel, MD, PhD, Pierre Fenaux, MD, PhD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Andrea Tu, PhD, Phoebe Yang, PhD, Alice C. Fan, MD, Scott C. Kogan, MD, Irving L. Weissman, MD, Dean W. Felsher, MD, PhD, Marika Pla, PhD, Robert West, PhD, Christine Chomienne, MD, PhD
Journal: Blood
Blood (2010) 116 (21): 3308.
https://doi.org/10.1182/blood.V116.21.3308.3308
Published: 2010
Journal Articles

Treatment of Higher Risk Myelodysplastic Syndrome Patients Unresponsive to Hypomethylating Agents with ON 01910.Na

Mahesh Seetharam, MD, Mai Tran, Alice C. Fan, MD, Liwen Xu, PhD, John P. Renschler, Dean W. Felsher, MD, PhD, Kunju Sridhar, PhD, Francois Wilhelm, MD, PhD., Peter L. Greenberg, MD
Journal: Blood
Blood (2010) 116 (21): 4010.
https://doi.org/10.1182/blood.V116.21.4010.4010
Published: 2010
Journal Articles

Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC -induced lymphomagenesis

Catherine M. Shachaf, Omar D. Perez, Sawsan Youssef, Alice C. Fan, Sailaja Elchuri, Matthew J. Goldstein, Amy E. Shirer, Orr Sharpe, Joy Chen, Dennis J. Mitchell, Maria Chang, Garry P. Nolan, Lawrence Steinman, Dean W. Felsher
Journal: Blood
Blood (2007) 110 (7): 2674–2684.
https://doi.org/10.1182/blood-2006-09-048033
Published: 2007
Includes: Supplemental data
Journal Articles

Nano-Fluidic Detection of Oncoprotein Signaling in Preclinical and Patient Lymphoma Samples.

Alice C. Fan, MD, Debabrita Deb-Basu, Ph.D., Melissa Horoschak, Amy Shirer, M.D., David Voehringer, Ph.D, Roger O’Neill, Ph.D, Dean W. Felsher, M.D., Ph.D.
Journal: Blood
Blood (2006) 108 (11): 2527.
https://doi.org/10.1182/blood.V108.11.2527.2527
Published: 2006
Journal Articles

Two Oncogenic Hits Are Required To Initiate Lymphomagenesis in Adult, but Not Neonatal Hosts.

Alice C. Fan, MD, Sylvie Giuriato, PhD, Asa Karlsson, Ph.D, Rose Ann Padua, Ph.D, Dean W. Felsher, MD, PhD
Journal: Blood
Blood (2005) 106 (11): 2604.
https://doi.org/10.1182/blood.V106.11.2604.2604
Published: 2005
Journal Articles

Cooperation between MYC and BCL2 to Induce Lymphoma Is Uncovered in an Adult Context.

Alice C. Fan, M.D., Sylvie Giuriato, Ph.D., Charles Feng, Rose Ann Padua, Ph.D., Dean Felsher, M.D., Ph. D.
Journal: Blood
Blood (2004) 104 (11): 1530.
https://doi.org/10.1182/blood.V104.11.1530.1530
Published: 2004