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Journal Articles

The Pyruvate Kinase Activator Mitapivat Ameliorates Anemia and Prevents Iron Overload in a Mouse Model of Hereditary Spherocytosis

Alessandro Mattè, BSc,PhD, Wilson Anand, Enrica Federti, PhD, Charles Kung, PhD, Penelope A. Kosinski, MS, Veronica Riccardi, Iana Iatcenko, Lenny Dang, PhD, Christophe Leboeuf, Anne Janin, PhD, Carlo Brugnara, MD, Mohandas Narla, DSc, Lucia De Franceschi, MD

Blood (2020) 136 (Supplement 1): 29.

https://doi.org/10.1182/blood-2020-142232

Published: 2020

Journal Articles

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

Alessandro Mattè, BSc,PhD, Enrica Federti, PhD, Antonio Rechiutti, Amtonella Panataleo, Roberta Russo, Francesco Turrini, MD PhD, Angela Siciliano, Pierre Louis Tharaux, MD PhD, Wassim El Nemer, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Wilson Babu, Achille Iolascon, MD PhD, Carlo Brugnara, MD, Lucia De Franceschi, MD

Blood (2018) 132 (Supplement 1): 725.

https://doi.org/10.1182/blood-2018-99-115832

Published: 2018

Journal Articles

KIR3DL2 expression in cutaneous T-cell lymphomas: expanding the spectrum for KIR3DL2 targeting

Maxime Battistella, Christophe Leboeuf, Caroline Ram-Wolff, Charlotte Hurabielle, Cécile Bonnafous, Hélène Sicard, Armand Bensussan, Martine Bagot, Anne Janin

Blood (2017) 130 (26): 2900–2902.

https://doi.org/10.1182/blood-2017-06-792382

Published: 2017

Includes: Supplemental data

Journal Articles

Reprogramming Cell-Signaling By Delivering the Catalytic Domain of Ptpgr Ameliorates Anemia of β-Thalassemia

Alessandro Mattè, PhD, Elisabetta Beneduce, Michela Mirenda, PhD, Roberta Russo, Achille Iolascon, MD PhD, Antonella Pantaleo, PhD, Francesco Turrini, MD PhD, Angela Siciliano, Enrica Federti, PhD, Serge Cedrick, Anne Janin, PhD, Christophe Leboeuf, Carlo Laudanna, MD, Lucia De Franceschi, MD

Blood (2017) 130 (Supplement 1): 2219.

https://doi.org/10.1182/blood.V130.Suppl_1.2219.2219

Published: 2017

Journal Articles

Peroxiredoxin-2: A Novel Factor Involved in Iron Homeostasis

Alessandro Mattè, PhD, Luigia De Falco, Enrica Federti, Sonia Levi, PhD, Achille Iolascon, MD PhD, Giorgia Federico, Narla Mohandas, DSc, Anne Janin, MD PhD, Mariasole Bruno, Christophe Leboeuf, PhD, Soo Young Choi, PhD, Dae Won Kim, Francesco Dima, MD, Angela Siciliano, Lucia De Franceschi, MD

Blood (2015) 126 (23): 406.

https://doi.org/10.1182/blood.V126.23.406.406

Published: 2015

Journal Articles

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

Blood (2014) 124 (21): 3249.

https://doi.org/10.1182/blood.V124.21.3249.3249

Published: 2014

Journal Articles

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Blood (2013) 122 (16): 2864–2876.

https://doi.org/10.1182/blood-2012-07-445635

Published: 2013

Includes: Supplemental data

Journal Articles

Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice

Sara Santos Franco, PhD student, Luigia De Falco, PhD, Saghi Ghaffari, MD, PhD, Carlo Brugnara, M.D., David Sinclair, PhD, Achille Iolascon, MD, PhD, Mohandas Narla, DSc, Mariarita Bertoldi, PhD, Christophe Lebouf, PhD, Anne Janin, MD, PhD, Angela Siciliano, Mrs, Pauline Rimmele, PhD, Maria Domenica Cappellini, MD, Shady Michan, PhD, Elisa Zoratti, PhD, Lucia De Franceschi, MD

Blood (2012) 120 (21): 3191.

https://doi.org/10.1182/blood.V120.21.3191.3191

Published: 2012

Journal Articles

BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

Petra Gorombei, MSc, Beurlet Stephanie, DMV, PhD, Nader Omidvar, PhD, Krief Patricia, PhD, Le Pogam Carole, MSc, Pierre de la Grange, PhD, Leboeuf Christophe, MD, PhD, Anne Janin, MD, PhD, Noguera Maria-Elena, MD, Marina Konopleva, MD, PhD, Michael Andreeff, MD, PhD, Pla Marika, PhD, West Robert, PhD, Pierre Fenaux, MD, PhD, Christine Chomienne, MD, PhD, Rose Ann Padua, PhD

Blood (2012) 120 (21): 678.

https://doi.org/10.1182/blood.V120.21.678.678

Published: 2012

Journal Articles

NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

Blood (2012) 120 (21): 3835.

https://doi.org/10.1182/blood.V120.21.3835.3835

Published: 2012

Journal Articles

Fecal calprotectin and alpha-1 antitrypsin predict severity and response to corticosteroids in gastrointestinal graft-versus-host disease

Paula Rodriguez-Otero, Raphael Porcher, Régis Peffault de Latour, Margarita Contreras, Yoram Bouhnik, Aliénor Xhaard, Annalisa Andreoli, Patricia Ribaud, Nathalie Kapel, Anne Janin, Gérard Socié, Marie Robin

Blood (2012) 119 (24): 5909–5917.

https://doi.org/10.1182/blood-2011-12-397968

Published: 2012

Includes: Supplemental data

Journal Articles

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes

Keli L. Hippen, Christoph Bucher, Dawn K. Schirm, Amanda M. Bearl, Ty Brender, Kathy A. Mink, Kimberly S. Waggie, Regis Peffault de Latour, Anne Janin, Julie M. Curtsinger, Stacey R. Dillon, Jeffrey S. Miller, Gerard Socie, Bruce R. Blazar

Blood (2012) 119 (2): 619–628.

https://doi.org/10.1182/blood-2011-07-368027

Published: 2012

Includes: Supplemental data

Journal Articles

Lack of Correlation of Endospcopy Findings and Pathological Results In GI-GvHD

Julie Abraham, Anne Janin, PhD, MD, Jean-Marc Gornet, Marie Robin, Regis Peffault de Latour, Patricia Ribaud, Jean-Yves Mary, Marc Lemann, Raphael Porcher, Gerard Socie

Blood (2010) 116 (21): 2339.

https://doi.org/10.1182/blood.V116.21.2339.2339

Published: 2010

Journal Articles

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

Blood (2010) 116 (21): 3308.

https://doi.org/10.1182/blood.V116.21.3308.3308

Published: 2010

Journal Articles

Th17/Treg ratio in human graft-versus-host disease

Philippe Ratajczak, Anne Janin, Regis Peffault de Latour, Christophe Leboeuf, Allison Desveaux, Keyvan Keyvanfar, Marie Robin, Emmanuel Clave, Corine Douay, Anne Quinquenel, Claire Pichereau, Philippe Bertheau, Jean Yves Mary, Gérard Socié

Blood (2010) 116 (7): 1165–1171.

https://doi.org/10.1182/blood-2009-12-255810

Published: 2010

Journal Articles

DNA vaccination with all- trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4 + and CD8 + T-cell activation in an acute promyelocytic leukemia mouse model

Kouichi Furugaki, Katerina Pokorna, Carole Le Pogam, Masayuki Aoki, Murielle Reboul, Véronique Bajzik, Patricia Krief, Anne Janin, Marie-Elena Noguera, Robert West, Dominique Charron, Christine Chomienne, Marika Pla, Hélène Moins-Teisserenc, Rose Ann Padua

Blood (2010) 115 (3): 653–656.

https://doi.org/10.1182/blood-2007-08-109009

Published: 2010

Includes: Supplemental data

Journal Articles

The Combination of Arsenic Trioxide and Interferon-Alpha Eradicates Leukemia Initiating Cells in TAX-Driven Murine Adult T Cell Leukemia/Lymphoma.

Ali Bazarbachi, MD, PhD, Hiba El Hajj, Marwan El-Sabban, Hideki Hasegawa, Ghazi Zaatari, Shahrazad Saab, Anne Janin, Rami Mahfouz, Rihab Nasr, Youmna Kfoury, Christophe Nicot, Olivier Hermine, William Hall, Hugues de The, MD, PhD

Blood (2009) 114 (22): 2714.

https://doi.org/10.1182/blood.V114.22.2714.2714

Published: 2009

Journal Articles

Donor-derived oral squamous cell carcinoma after allogeneic bone marrow transplantation

Anne Janin, Hideyuki Murata, Christophe Leboeuf, Jean-Michel Cayuela, Eliane Gluckman, Luc Legrès, Allison Desveaux, Mariana Varna, Philippe Ratajczak, Jean Soulier, Hugues de Thé, Philippe Bertheau, Gérard Socié

Blood (2009) 113 (8): 1834–1840.

https://doi.org/10.1182/blood-2008-07-171702

Published: 2009

Includes: Supplemental data

Journal Articles

Phosphodiesterase-4 Inhibition Reduces Ischemic/Reperfusion Liver Injury in a Mouse Model for Sickle Cell Disease.

Alida Filippini, Giorgio Malpeli, Anne Janin, Orah S Platt, Christhope Leboeuf, Aldo Scarpa, Yves Beuzard, Lucia De Franceschi, MD

Blood (2008) 112 (11): 1444.

https://doi.org/10.1182/blood.V112.11.1444.1444

Published: 2008

Journal Articles

ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia

Nader Omidvar, Stephanie Beurlet, Carole Le Pogam, Anne Janin, Christophe Leboeuf, Annie Soulie, Niclas Setterblad, Maria-Elena Noguera, Laure Sarda-Mantel, Pascal Merlet, Marika Pla, Scott C. Kogan, MD, Irving L Weissman, Marina Konopleva, William Bormann, Michael Andreeff, Christine Chomienne, Rose Ann Padua

Blood (2008) 112 (11): 848.

https://doi.org/10.1182/blood.V112.11.848.848

Published: 2008

NARROW

The Pyruvate Kinase Activator Mitapivat Ameliorates Anemia and Prevents Iron Overload in a Mouse Model of Hereditary Spherocytosis

Imatinib Protects Against Hypoxia/Reoxygenation Induced Lung and Kidney Injury in a Humanized Mouse Model for SCD

KIR3DL2 expression in cutaneous T-cell lymphomas: expanding the spectrum for KIR3DL2 targeting

Reprogramming Cell-Signaling By Delivering the Catalytic Domain of Ptpgr Ameliorates Anemia of β-Thalassemia

Peroxiredoxin-2: A Novel Factor Involved in Iron Homeostasis

Efficacy of ABT-737, a BCL-2 Inhibitor, in an NRAS/BCL2 Mouse Model of High Risk Myelodysplasia (HR-MDS) By Targeting Pathways Identified By Gene Expression Profiling

BCL-2 inhibition with ABT-737 prolongs survival in an NRAS/BCL-2 mouse model of AML by targeting primitive LSK and progenitor cells

Resveratrol Induces Erythroid Maturation by Activating FOXO3 and Improves in Vivo Erythropoiesis in Normal and Beta -Thalassemic Mice

BCL-2 Inhibition with ABT-737 Prolongs Survival in an NRAS/BCL2-Mediated MOUSE MODEL of Myelodyspastic Syndrome (MDS) Progressing to ACUTE Myelogenous Leukemia (AML) by Targeting Leukemia Initiating CELLS

NRAS:BCL-2 Complex Localization Determines Anti-Apoptotic Features Associated with Progressive Disease in Myelodysplastic Syndromes (MDS)

Fecal calprotectin and alpha-1 antitrypsin predict severity and response to corticosteroids in gastrointestinal graft-versus-host disease

Blocking IL-21 signaling ameliorates xenogeneic GVHD induced by human lymphocytes

Lack of Correlation of Endospcopy Findings and Pathological Results In GI-GvHD

ABT-737 Targets Leukemic Stem Cells In Mouse Models of Mutant NRASD12/hBCL-2- Mediated Acute Myeloid Leukemia Progression with Increased Survival

Th17/Treg ratio in human graft-versus-host disease

DNA vaccination with all- trans retinoic acid treatment induces long-term survival and elicits specific immune responses requiring CD4 + and CD8 + T-cell activation in an acute promyelocytic leukemia mouse model

The Combination of Arsenic Trioxide and Interferon-Alpha Eradicates Leukemia Initiating Cells in TAX-Driven Murine Adult T Cell Leukemia/Lymphoma.

Donor-derived oral squamous cell carcinoma after allogeneic bone marrow transplantation

Phosphodiesterase-4 Inhibition Reduces Ischemic/Reperfusion Liver Injury in a Mouse Model for Sickle Cell Disease.

ABT-737 Targets Intrinsic Apoptosis during Cooperation of BCL-2 and Oncogenic NRAS in An in Vivo Progression Model of Myelodysplasia/Acute Myeloid Leukaemia

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American Society of Hematology

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American Society of Hematology

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