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Sarah T Diepstraten
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Journal Articles

Direct, Potent, and TP53-Independent Activity of Sting Agonists Against Acute Myeloid Leukaemia Enhances Venetoclax Efficacy In Vivo

Yin Yuan, Sarah T Diepstraten, Fiona C. Brown, Veronique Litalien, Andreas Strasser, Gemma L Kelly, Andrew W. Roberts, Andrew H. Wei
Journal: Blood
Blood (2023) 142 (Supplement 1): 4163.
https://doi.org/10.1182/blood-2023-179698
Published: 2023
Journal Articles

Impaired ribosome biogenesis checkpoint activation induces p53-dependent MCL-1 degradation and MYC-driven lymphoma death

Ana Domostegui, Suresh Peddigari, Carol A. Mercer, Flavia Iannizzotto, Marta L. Rodriguez, Marta Garcia-Cajide, Virginia Amador, Sarah T. Diepstraten, Gemma L. Kelly, Ramón Salazar, Sara C. Kozma, Eric P. Kusnadi, Jian Kang, Antonio Gentilella, Richard B. Pearson, George Thomas, Joffrey Pelletier
Journal: Blood
Blood (2021) 137 (24): 3351–3364.
https://doi.org/10.1182/blood.2020007452
Published: 2021
Includes: Supplemental data
Journal Articles

Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemias

Rachel Thijssen, Sarah T. Diepstraten, Donia Moujalled, Edward Chew, Christoffer Flensburg, Melissa X. Shi, Michael A. Dengler, Veronique Litalien, Sarah MacRaild, Maoshan Chen, Natasha S. Anstee, Boris Reljić, Sarah S. Gabriel, Tirta M. Djajawi, Chris D. Riffkin, Brandon J. Aubrey, Catherine Chang, Lin Tai, Zhen Xu, Thomas Morley, Giovanna Pomilio, Claudia Bruedigam, Axel Kallies, David A. Stroud, Ashish Bajel, Ruth M. Kluck, Steven W. Lane, Marie Schoumacher, Sébastien Banquet, Ian J. Majewski, Andreas Strasser, Andrew W. Roberts, David C. S. Huang, Fiona C. Brown, Gemma L. Kelly, Andrew H. Wei
Journal: Blood
Blood (2021) 137 (20): 2721–2735.
https://doi.org/10.1182/blood.2020010167
Published: 2021
Includes: Supplemental data