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Donia M. Moujalled
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Journal Articles

Co-Targeting BCL-2 and MCL1 (via CDK9) in Pre-Clinical Models of High-Risk Acute Lymphoblastic Leukemia

Donia M. Moujalled, Seong Lin Khaw, Teresa Sadras, Giovanna Pomilio, Thomas Morley, Veronique Litalien, Louise Ludlow, Paul G. Ekert, Diane Hanna
Journal: Blood
Blood (2024) 144 (Supplement 1): 1419.
https://doi.org/10.1182/blood-2024-202757
Published: 2024
Journal Articles

CD74 Antibody Conjugated to an MCL1 Inhibitor (S227928) Combines Synergistically with Venetoclax to Enhance Killing of Acute Myeloid Leukemia

Donia M. Moujalled, Giovanna Pomilio, Thomas Morley, Veronique Litalien, Natasha S. Anstee, Sun Loo, Zhi-Han Yeoh, Clovis Boibessot, Laura Bresson, Ana-Leticia Maragno, Caroline Liot, Andrew H Wei
Journal: Blood
Blood (2024) 144 (Supplement 1): 4136.
https://doi.org/10.1182/blood-2024-202691
Published: 2024
Journal Articles

Acquired mutations in BAX confer resistance to BH3-mimetic therapy in acute myeloid leukemia

Clinical Trials & Observations
Donia M. Moujalled, Fiona C. Brown, Chong Chyn Chua, Michael A. Dengler, Giovanna Pomilio, Natasha S. Anstee, Veronique Litalien, Ella Thompson, Thomas Morley, Sarah MacRaild, Ing S. Tiong, Rhiannon Morris, Karen Dun, Adrian Zordan, Jaynish Shah, Sebastien Banquet, Ensar Halilovic, Erick Morris, Marco J. Herold, Guillaume Lessene, Jerry M. Adams, David C. S. Huang, Andrew W. Roberts, Piers Blombery, Andrew H. Wei
Journal: Blood
Blood (2023) 141 (6): 634–644.
https://doi.org/10.1182/blood.2022016090
Published: 2023
Includes: Supplemental data
Journal Articles

Combination Therapy of FLT3 Tyrosine Kinase Inhibitors and BH3 Mimetics Targeting Antiapoptotic MCL-1 Synergistically Eliminates FLT3-ITD Acute Myeloid Leukemia Cells in Vitro and In Vivo

Anna Skwarska, Donia M Moujalled, Paul F Panis, Shraddha Patel, Qi Zhang, Shelley Herbrich, Vinitha Kurvilla, Natalia Baran, Giovanna Pomilio, Ensar Halilovic, Prakash Mistry, Vivian Ruvolo, Peter P. Ruvolo, Alix Derréal, Sebastien Banquet, Magdalena Niemira, Adam Kretowski, Naval Daver, Michael Andreeff, Andrew H. Wei, Marina Konopleva
Journal: Blood
Blood (2021) 138 (Supplement 1): 2248.
https://doi.org/10.1182/blood-2021-151042
Published: 2021
Journal Articles

Acquired Mutations in BAX Confer Resistance to BH3 Mimetics in Acute Myeloid Leukemia

Donia M Moujalled, PhD, Fiona C Brown, PhD, Giovanna Pomilio, Natasha S Anstee, PhD, Veronique Litalien, Ella R Thompson, PhD BSc, Thomas Morley, Sarah MacRaild, Chong C Chua, MBBS, BMedSc, SéBastien Banquet, PhD, Maia Chanrion, Ana-Leticia Maragno, PhD, Marie Schoumacher, Marco J Herold, PhD, Guillaume Lessene, PhD, Olivier Geneste, PhD, David C.S. Huang, MBBS MRCP PhD, Andrew W Roberts, MBBS, Piers Blombery, MBBS, Andrew Wei, MBBS,PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 7–8.
https://doi.org/10.1182/blood-2020-136872
Published: 2020
Journal Articles

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

Chong Chyn Chua, MBBS, John Reynolds, PhD, Jessica M Salmon, PhD, Chun Fong, Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Ing Soo Tiong, MBBS,FRACP,FRCPA, Shaun Fleming, MBBS,, Sarah MacRaild, Donia M Moujalled, PhD, Giovanna Pomilio, Nik Cummings, Julie McManus, Adam Ivey, BSc, MSc, PhD, Purvi M Kakadia, PhD, Stefan K. Bohlander, MD, Andrew W. Roberts, MBBS, PhD FRACP, FRCPA, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 462.
https://doi.org/10.1182/blood-2019-126640
Published: 2019
Journal Articles

Combined BCL-2 and HDAC Targeting Has Potent and TP53 Independent Activity in AML

Jessica M Salmon, PhD, Giovanna Pomilio, Donia M Moujalled, PhD, Sarah Macraild, Charis E Teh, PhD, Sewa Riajl, PhD, Adam Ivey, BSc, MSc, PhD, Tse-Chieh Teh, MD, Paul G Ekert, Laurence Kraus-Berthier, Ioana Kloos, Marie Schoumacher, Daniel Gray, Andrew H Wei, MBBS, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1426.
https://doi.org/10.1182/blood-2018-99-117403
Published: 2018
Journal Articles

Identification of Potent BH3-Mimetic Combinations Targeting Pro-Survival Pathways in Human B-Cell Acute Lymphoblastic Leukemia

Donia M Moujalled, PhD, Diane T Hanna, Giovanna Pomilio, Veronique Litalien, Shaun Fleming, Marie Chanrion, Ana-Leticia Maragno, Laurence Kraus-Berthier, Seong Lin Khaw, Guillaume Lessene, David Huang, Andrew W. Roberts, MBBS, PhD, Olivier Geneste, Paul G Ekert, Ashley P Ng, Andrew H Wei, MBBS,PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 567.
https://doi.org/10.1182/blood-2018-99-114051
Published: 2018