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Journal Articles

Germline Missense Variants in SH2B3 Underpin Platelet Count Variation and Inherited MPN

Liesl Butler, Christine Lee, Graham William Magor, Rhiannon Morris, Michael Tallack, Charlene Lam, Adam Ivey, Jane Lin, Zihao Deng, Andrew Grigg, Jane Mason, Malaika Perchard, Helen Weston, Nik Cummings, Andrew Brooks, Jeffrey J Babon, Andrew J Murphy, Jessica M Salmon, Andrew Charles Perkins
Journal: Blood
Blood (2022) 140 (Supplement 1): 1093–1094.
https://doi.org/10.1182/blood-2022-159416
Published: 2022
Journal Articles

Anti-Leukemic Activity of Single Agent Venetoclax in Newly Diagnosed Acute Myeloid Leukemia: A Sub-Set Analysis of the Caveat Study

Chong Chyn Chua, MBBS, John Reynolds, PhD, Jessica M Salmon, PhD, Chun Fong, Stephen B Ting, MB BS, FRACP, FRCPA, PhD, Ing Soo Tiong, MBBS,FRACP,FRCPA, Shaun Fleming, MBBS,, Sarah MacRaild, Donia M Moujalled, PhD, Giovanna Pomilio, Nik Cummings, Julie McManus, Adam Ivey, BSc, MSc, PhD, Purvi M Kakadia, PhD, Stefan K. Bohlander, MD, Andrew W. Roberts, MBBS, PhD FRACP, FRCPA, Andrew H. Wei, PhD FRACP, FRCPA, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 462.
https://doi.org/10.1182/blood-2019-126640
Published: 2019
Journal Articles

Post-Allogeneic Stem Cell Transplant Surveillance of CD34+ Sorted Peripheral Blood to Quantify Emergent DNMT3A, IDH and NPM1 clones and Correlation with Clinical Outcome

Shaun Fleming, MBBS(Hons) FRACP FRCPA, Nik Cummings, Tongted Das, Adam Ivey, BSc, MSc, PhD, Julie McManus, Sharon Avery, MBBS, FRACP, FRCPA, Sushrut S. Patil, FRACP, FRCPA, Patricia A. Walker, MBBS, David J. Curtis, MBBS,PhD FRACP, FRCPA, Andrew Spencer, MD, Andrew Wei, MBBS, PhD FRACP, FRCPA
Journal: Blood
Blood (2017) 130 (Supplement 1): 2674.
https://doi.org/10.1182/blood.V130.Suppl_1.2674.2674
Published: 2017
Journal Articles

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Diana Iarossi, Saumya E. Samaraweera, Nik Cummings, Hayley S. Ramshaw, Daniel Thomas, Andrew H. Wei, Angel F. Lopez, Richard J. D’Andrea, Ian D. Lewis, Stuart M. Pitson
Journal: Blood
Blood (2017) 129 (6): 771–782.
https://doi.org/10.1182/blood-2016-06-720433
Published: 2017
Includes: Supplemental data
Journal Articles

Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2 , and Correlates with More Aggressive AML

Saumya E Samaraweera, PhD, Francine E. Garrett-Bakelman, MD PhD, Yaseswini Neelamraju, Michelle Perugini, PhD, Debora A. Casolari, PhD, Diana Iarossi, Sarah C Bray, PhD, Caroline Sheridan, Tak C Lee, M.S., Ing Soo Tiong, MBChB, Silke Danner, Nik Cummings, BSc, Monica L. Guzman, PhD, Gail J. Roboz, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Andrew Wei, Christopher E. Mason, PhD, Christopher Y. Park, MD PhD, Ross L. Levine, MD, Martin Carroll, MD, Michael W. Becker, MD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Ari Melnick, MD, Richard D'Andrea, PhD
Journal: Blood
Blood (2016) 128 (22): 2877.
https://doi.org/10.1182/blood.V128.22.2877.2877
Published: 2016
Journal Articles

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML

Clinical Trials & Observations
Sewa Rijal, Shaun Fleming, Nik Cummings, Natalie K. Rynkiewicz, Lisa M. Ooms, Nhu-Y. N. Nguyen, Tse-Chieh Teh, Sharon Avery, Julie F. McManus, Anthony T. Papenfuss, Catriona McLean, Mark A. Guthridge, Christina A. Mitchell, Andrew H. Wei
Journal: Blood
Blood (2015) 125 (18): 2815–2824.
https://doi.org/10.1182/blood-2014-09-603555
Published: 2015
Includes: Supplemental data
Journal Articles

The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation

Michelle Perugini, PhD, Saumya E Samaraweera, PhD, Anna L Brown, PhD, Nik Cummings, BSc, Silke Danner, Ing Soo Tiong, MBChB, Francine E Garrett-Bakelman, MD PhD, Martin P. Carroll, MD, Michael W. Becker, MD, Stephen S. Chung, MD, Christopher Y. Park, MD PhD, Christopher E Mason, PhD, Monica L. Guzman, PhD, Ross L. Levine, MD, Ari M Melnick, MD, Luen Bik To, MBBS, PhD, Andrew H Wei, MBBS, PhD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2014) 124 (21): 69.
https://doi.org/10.1182/blood.V124.21.69.69
Published: 2014
Journal Articles

Methylation of the Proximal Promoter of GADD45A Is Common in Acute Myeloid Leukemia and Is Associated with Poor Survival.

Richard J D'Andrea, PhD, Michelle Perugini, PhD, Sonya M Diakiw, PhD, Chung H Kok, PhD, Diana Salerno, Nik Cummings, BSc, Anna L Brown, PhD, Silke Danner, Peter G Bardy, MBBS, FRACP, FRCPA, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD
Journal: Blood
Blood (2012) 120 (21): 2396.
https://doi.org/10.1182/blood.V120.21.2396.2396
Published: 2012
Journal Articles

A Regulatory Promoter Polymorphism and Hypermethylation of Intron 1 Are Associated with Reduced Expression of KLF5 and Inferior Survival in AML

Anna L Brown, PhD, Sonya M Diakiw, PhD, Michelle Perugini, PhD, Nik Cummings, BSc, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2012) 120 (21): 3508.
https://doi.org/10.1182/blood.V120.21.3508.3508
Published: 2012
Journal Articles

Azacitidine in Combination with the mTOR Inhibitor Everolimus in Relapsed and Refractory AML

Andrew H Wei, MBBS, PhD, Peter T. Tan, MBBS, John Catalano, MD, Patricia A. Walker, MBBS, FRACP, FRCPA, Anthony P. Schwarer, MD, Sharon Avery, MBBS, Sushrut S. Patil, FRACP FRCPA, Stephen Opat, MD, Nik Cummings, BSc, Andrew Spencer, MD
Journal: Blood
Blood (2011) 118 (21): 2599.
https://doi.org/10.1182/blood.V118.21.2599.2599
Published: 2011