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Craig T. Wallington-Beddoe
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Journal Articles

Ceramide-induced integrated stress response overcomes Bcl-2 inhibitor resistance in acute myeloid leukemia

Alexander C. Lewis, Victoria S. Pope, Melinda N. Tea, Manjun Li, Gus O. Nwosu, Thao M. Nguyen, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Dovile Anderson, Darren J. Creek, Maurizio Costabile, Saira R. Ali, Chloe A. L. Thompson-Peach, B. Kate Dredge, Andrew G. Bert, Gregory J. Goodall, Paul G. Ekert, Anna L. Brown, Richard D’Andrea, Nirmal Robinson, Melissa R. Pitman, Daniel Thomas, David M. Ross, Briony L. Gliddon, Jason A. Powell, Stuart M. Pitson
Journal: Blood
Blood (2022) 139 (26): 3737–3751.
https://doi.org/10.1182/blood.2021013277
Published: 2022
Includes: Supplemental data
Journal Articles

Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Jason A. Powell, Alexander C. Lewis, Wenying Zhu, John Toubia, Melissa R. Pitman, Craig T. Wallington-Beddoe, Paul A. B. Moretti, Diana Iarossi, Saumya E. Samaraweera, Nik Cummings, Hayley S. Ramshaw, Daniel Thomas, Andrew H. Wei, Angel F. Lopez, Richard J. D’Andrea, Ian D. Lewis, Stuart M. Pitson
Journal: Blood
Blood (2017) 129 (6): 771–782.
https://doi.org/10.1182/blood-2016-06-720433
Published: 2017
Includes: Supplemental data
Journal Articles

Evaluation Of Sphingosine Kinase 1 As a Therapeutic Target In B-Lineage Acute Lymphoblastic Leukemia

Craig T Wallington-Beddoe, BSc, MBBS, PhD, FRACP, FRCPA, Stuart M Pitson, BAppSc, PhD, Jason A Powell, BSc, PhD, Kenneth F Bradstock, MBBS, PhD, FRACP, FRCPA, Linda J Bendall, BSc, PhD
Journal: Blood
Blood (2013) 122 (21): 1426.
https://doi.org/10.1182/blood.V122.21.1426.1426
Published: 2013
Journal Articles

Identification of Sphingosine Kinases As Therapeutic Targets in B-Lineage Acute Lymphoblastic Leukemia

Craig T Wallington-Beddoe, BSc, MB BS, FRACP, FRCPA, Kenneth F Bradstock, MB, PhD, FRACP, FRCPA, Linda J Bendall, BSc, PhD
Journal: Blood
Blood (2012) 120 (21): 1499.
https://doi.org/10.1182/blood.V120.21.1499.1499
Published: 2012
Journal Articles

Sphingosine Kinase Inhibition Has Pre-Clinical Activity in Acute Lymphoblastic Leukemia,

Craig T. Wallington-Beddoe, BSc, MBBS, David Ho, BSc, Kenneth Francis Bradstock, MB, PhD, Linda J. Bendall, BSc, PhD
Journal: Blood
Blood (2011) 118 (21): 3573.
https://doi.org/10.1182/blood.V118.21.3573.3573
Published: 2011
Journal Articles

FTY720 Has Potent Anti-Leukemic Effects on Acute Lymphoblastic Leukemia Cells and Results In Caspase Independent Cell Death

Craig T. Wallington-Beddoe, BSc, MBBS, John Hewson, MBBS, Kenneth Francis Bradstock, MB, PhD, Linda J. Bendall, BSc, PhD
Journal: Blood
Blood (2010) 116 (21): 3260.
https://doi.org/10.1182/blood.V116.21.3260.3260
Published: 2010