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Journal Articles

STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia

Cedric S. Tremblay, Jesslyn Saw, Jacqueline A. Boyle, Katharina Haigh, Veronique Litalien, Hannah McCalmont, Kathryn Evans, Richard B. Lock, Stephen M. Jane, Jody J. Haigh, David J. Curtis

Blood (2023) 142 (3): 274–289.

https://doi.org/10.1182/blood.2022016322

Published: 2023

Includes: Supplemental data

Journal Articles

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Fiona C. Brown, Ashlee J. Conway, Loretta Cerruti, Janelle E. Collinge, Catriona McLean, James S. Wiley, Ben T. Kile, Stephen M. Jane, David J. Curtis

Blood (2015) 126 (26): 2863–2870.

https://doi.org/10.1182/blood-2014-10-609362

Published: 2015

Includes: Supplemental data

Journal Articles

Selective Inhibitors of Arginine Methyl Transferase 5 (PRMT5) As a Novel Treatment for β-Thalassemia and Sickle Cell Disease.

Blood (2012) 120 (21): 2129.

https://doi.org/10.1182/blood.V120.21.2129.2129

Published: 2012

Journal Articles

A Novel DNM2 Mutation Displaying Embryonic Lethality and Impaired Transferrin Uptake Identified in a Mouse ENU Mutagenesis Screen for Genes Perturbing Erythropoiesis

Fiona C Brown, BSc, Michael Collett, BSc, Phillip J Robinson, PhD, James C Whisstock, PhD, Douglas J. Hilton, Benjamin T. Kile, Stephen M Jane, FRACP, FRCPA, MBBS, PhD, David J. Curtis, M.D., Ph.D.

Blood (2012) 120 (21): 608.

https://doi.org/10.1182/blood.V120.21.608.608

Published: 2012

Journal Articles

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

Christopher I. Slape, Jesslyn Saw, Jeremy B. M. Jowett, Peter D. Aplan, Andreas Strasser, Stephen M. Jane, David J. Curtis

Blood (2012) 120 (12): 2475–2483.

https://doi.org/10.1182/blood-2012-05-430736

Published: 2012

Includes: Supplemental data

Journal Articles

ENU Mutagenesis in the Mouse for Identification of Genes Regulating Erythropoiesis: a Mouse Mutant with An Activating Mutation of the KCl Cotransporter, KCC1 Causing Dehydrated Red Cells

David J. Curtis, MD, PhD, Fiona Brown, BSc, James Wiley, MD PhD, Shwen Ho, PhD, Douglas J. Hilton, PhD, Benjamin T. Kile, PhD, Stephen M Jane

Blood (2011) 118 (21): 684.

https://doi.org/10.1182/blood.V118.21.684.684

Published: 2011

Journal Articles

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Nhu-Y. N. Nguyen, Mhairi J. Maxwell, Lisa M. Ooms, Elizabeth M. Davies, Adrienne A. Hilton, Janelle E. Collinge, Douglas J. Hilton, Benjamin T. Kile, Christina A. Mitchell, Margaret L. Hibbs, Stephen M. Jane, David J. Curtis

Blood (2011) 117 (20): 5362–5371.

https://doi.org/10.1182/blood-2011-01-331041

Published: 2011

Includes: Supplemental data

Journal Articles

Dissecting the Mechanism of Apoptosis and Leukemic Transformation In Myelodysplasia

Christopher I Slape, Jesslyn Saw, Laura M Failla, Peter D Aplan, Stephen M Jane, David J Curtis

Blood (2010) 116 (21): 610.

https://doi.org/10.1182/blood.V116.21.610.610

Published: 2010

Journal Articles

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression

Gerhard Rank, Loretta Cerruti, Richard J. Simpson, Robert L. Moritz, Stephen M. Jane, Quan Zhao

Blood (2010) 116 (9): 1585–1592.

https://doi.org/10.1182/blood-2009-10-251116

Published: 2010

Includes: Supplemental data

Journal Articles

The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms

Sarah L. Siggins, Nhu-Y N. Nguyen, Matthew P. McCormack, Sumitha Vasudevan, Rehan Villani, Stephen M. Jane, Brandon J. Wainwright, David J. Curtis

Blood (2009) 114 (5): 995–1004.

https://doi.org/10.1182/blood-2009-03-208330

Published: 2009

Includes: Supplemental data

Journal Articles

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant

Gerhard Rank, Rosemary Sutton, Vikki Marshall, Rachel J. Lundie, Jacinta Caddy, Tony Romeo, Kate Fernandez, Matthew P. McCormack, Brian M. Cooke, Simon J. Foote, Brendan S. Crabb, David J. Curtis, Douglas J. Hilton, Benjamin T. Kile, Stephen M. Jane

Blood (2009) 113 (14): 3352–3362.

https://doi.org/10.1182/blood-2008-08-172841

Published: 2009

Includes: Supplemental data

Journal Articles

Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene

Jessica M. Salmon, Nicholas J. Slater, Mark A. Hall, Matthew P. McCormack, Stephen L. Nutt, Stephen M. Jane, David J. Curtis

Blood (2007) 110 (10): 3573–3581.

https://doi.org/10.1182/blood-2006-10-053124

Published: 2007

Journal Articles

Context-Specific Roles for Erythroid Krüppel-Like Factor (EKLF) in Co-Ordinate High Level Expression of the Murine α- and β-Globin Genes.

Valerie M. Jansen, BA, Shaji Ramachandran, PhD, Aurelie Desgardin, BS, Jin He, MD, Vishwas Parekh, MD, Stephen M. Jane, MD PhD, John M. Cunningham, MD

Blood (2006) 108 (11): 365.

https://doi.org/10.1182/blood.V108.11.365.365

Published: 2006

Journal Articles

An Erythoid-Specific Component of the Rhesus Stage Selector Protein, rNF-E4, Modulates γ-Globin Gene Expression Specifically.

Ruiqiong Wu, PhD, Aurelie Desgardin, B.S., Stephen M. Jane, M.D., John M. Cunningham, M.D.

Blood (2006) 108 (11): 1599.

https://doi.org/10.1182/blood.V108.11.1599.1599

Published: 2006

Journal Articles

A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis

Matthew P. McCormack, Mark A. Hall, Simone M. Schoenwaelder, Quan Zhao, Sarah Ellis, Julia A. Prentice, Ashleigh J. Clarke, Nicholas J. Slater, Jessica M. Salmon, Shaun P. Jackson, Stephen M. Jane, David J. Curtis

Blood (2006) 108 (7): 2248–2256.

https://doi.org/10.1182/blood-2006-02-002188

Published: 2006

Journal Articles

Repression of human γ-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

Quan Zhao, Wenlai Zhou, Gerhard Rank, Rosemary Sutton, Xi Wang, Helen Cumming, Loretta Cerruti, John M. Cunningham, Stephen M. Jane

Blood (2006) 107 (5): 2138–2145.

https://doi.org/10.1182/blood-2005-06-2497

Published: 2006

Journal Articles

Identification of Novel Erythropoietic Genes and Alleles Using a Large-Scale Chemical Mutagenesis Screen in Mice.

Stephen M. Jane, MD, PhD, Rosemary Sutton, MD, Gerhard Rank, PhD, Alana Auden, BSc, Warren Alexander, PhD, Benjamin Kile, PhD, Douglas Hilton, PhD, John M. Cunningham, MD, David Curtis, MD, PhD

Blood (2005) 106 (11): 565.

https://doi.org/10.1182/blood.V106.11.565.565

Published: 2005

Journal Articles

A Platelet Shedding Defect in Mice Lacking the Basic Helix-Loop-Helix Transcription Factor Scl.

Matthew P. McCormack, PhD, Mark A. Hall, PhD, Simone M. Schoenwaelder, PhD, Shaun P. Jackson, MD, PhD, Sarah Ellis, B.Sc, Stephen M. Jane, MD, PhD, David J. Curtis, MD, PhD

Blood (2005) 106 (11): 735.

https://doi.org/10.1182/blood.V106.11.735.735

Published: 2005

Journal Articles

Adoptive transfer of gene-engineered CD4 + helper T cells induces potent primary and secondary tumor rejection

Maria Moeller, Nicole M. Haynes, Michael H. Kershaw, Jacob T. Jackson, Michele W. L. Teng, Shayna E. Street, Loretta Cerutti, Stephen M. Jane, Joseph A. Trapani, Mark J. Smyth, Phillip K. Darcy

Blood (2005) 106 (9): 2995–3003.

https://doi.org/10.1182/blood-2004-12-4906

Published: 2005

Journal Articles

Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium

Joachim R. Göthert, Sonja E. Gustin, J. Anke M. van Eekelen, Uli Schmidt, Mark A. Hall, Stephen M. Jane, Anthony R. Green, Berthold Göttgens, David J. Izon, C. Glenn Begley

Blood (2004) 104 (6): 1769–1777.

https://doi.org/10.1182/blood-2003-11-3952

Published: 2004

NARROW

STAT5 activation promotes progression and chemotherapy resistance in early T-cell precursor acute lymphoblastic leukemia

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model

Selective Inhibitors of Arginine Methyl Transferase 5 (PRMT5) As a Novel Treatment for β-Thalassemia and Sickle Cell Disease.

A Novel DNM2 Mutation Displaying Embryonic Lethality and Impaired Transferrin Uptake Identified in a Mouse ENU Mutagenesis Screen for Genes Perturbing Erythropoiesis

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

ENU Mutagenesis in the Mouse for Identification of Genes Regulating Erythropoiesis: a Mouse Mutant with An Activating Mutation of the KCl Cotransporter, KCC1 Causing Dehydrated Red Cells

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Dissecting the Mechanism of Apoptosis and Leukemic Transformation In Myelodysplasia

Identification of a PRMT5-dependent repressor complex linked to silencing of human fetal globin gene expression

The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant

Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene

Context-Specific Roles for Erythroid Krüppel-Like Factor (EKLF) in Co-Ordinate High Level Expression of the Murine α- and β-Globin Genes.

An Erythoid-Specific Component of the Rhesus Stage Selector Protein, rNF-E4, Modulates γ-Globin Gene Expression Specifically.

A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis

Repression of human γ-globin gene expression by a short isoform of the NF-E4 protein is associated with loss of NF-E2 and RNA polymerase II recruitment to the promoter

Identification of Novel Erythropoietic Genes and Alleles Using a Large-Scale Chemical Mutagenesis Screen in Mice.

A Platelet Shedding Defect in Mice Lacking the Basic Helix-Loop-Helix Transcription Factor Scl.

Adoptive transfer of gene-engineered CD4 + helper T cells induces potent primary and secondary tumor rejection

Genetically tagging endothelial cells in vivo: bone marrow-derived cells do not contribute to tumor endothelium

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American Society of Hematology

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American Society of Hematology

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