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Nhu-Y N. Nguyen
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Journal Articles

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Nadine Hein, Donald P. Cameron, Katherine M. Hannan, Nhu-Y N. Nguyen, Chun Yew Fong, Jirawas Sornkom, Meaghan Wall, Megan Pavy, Carleen Cullinane, Jeannine Diesch, Jennifer R. Devlin, Amee J. George, Elaine Sanij, Jaclyn Quin, Gretchen Poortinga, Inge Verbrugge, Adele Baker, Denis Drygin, Simon J. Harrison, James D. Rozario, Jason A. Powell, Stuart M. Pitson, Johannes Zuber, Ricky W. Johnstone, Mark A. Dawson, Mark A. Guthridge, Andrew Wei, Grant A. McArthur, Richard B. Pearson, Ross D. Hannan
Journal: Blood
Blood (2017) 129 (21): 2882–2895.
https://doi.org/10.1182/blood-2016-05-718171
Published: 2017
Includes: Supplemental data
Journal Articles

Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML

Clinical Trials & Observations
Sewa Rijal, Shaun Fleming, Nik Cummings, Natalie K. Rynkiewicz, Lisa M. Ooms, Nhu-Y. N. Nguyen, Tse-Chieh Teh, Sharon Avery, Julie F. McManus, Anthony T. Papenfuss, Catriona McLean, Mark A. Guthridge, Christina A. Mitchell, Andrew H. Wei
Journal: Blood
Blood (2015) 125 (18): 2815–2824.
https://doi.org/10.1182/blood-2014-09-603555
Published: 2015
Includes: Supplemental data
Journal Articles

Targeting acute myeloid leukemia by dual inhibition of PI3K signaling and Cdk9-mediated Mcl-1 transcription

Daniel Thomas, Jason A. Powell, Francois Vergez, David H. Segal, Nhu-Y. N. Nguyen, Adele Baker, Tse-Chieh Teh, Emma F. Barry, Jean-Emmanuel Sarry, Erwin M. Lee, Tracy L. Nero, Anissa M. Jabbour, Giovanna Pomilio, Benjamin D. Green, Stéphane Manenti, Stefan P. Glaser, Michael W. Parker, Angel F. Lopez, Paul G. Ekert, Richard B. Lock, David C. S. Huang, Susie K. Nilsson, Christian Récher, Andrew H. Wei, Mark A. Guthridge
Journal: Blood
Blood (2013) 122 (5): 738–748.
https://doi.org/10.1182/blood-2012-08-447441
Published: 2013
Includes: Supplemental data
Journal Articles

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation

Nhu-Y. N. Nguyen, Mhairi J. Maxwell, Lisa M. Ooms, Elizabeth M. Davies, Adrienne A. Hilton, Janelle E. Collinge, Douglas J. Hilton, Benjamin T. Kile, Christina A. Mitchell, Margaret L. Hibbs, Stephen M. Jane, David J. Curtis
Journal: Blood
Blood (2011) 117 (20): 5362–5371.
https://doi.org/10.1182/blood-2011-01-331041
Published: 2011
Includes: Supplemental data
Journal Articles

The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms

Sarah L. Siggins, Nhu-Y N. Nguyen, Matthew P. McCormack, Sumitha Vasudevan, Rehan Villani, Stephen M. Jane, Brandon J. Wainwright, David J. Curtis
Journal: Blood
Blood (2009) 114 (5): 995–1004.
https://doi.org/10.1182/blood-2009-03-208330
Published: 2009
Includes: Supplemental data