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Journal Articles

Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas

Scott Boiko, Theresa Proia, Maryann San Martin, Gareth P. Gregory, Michelle Min Wu, Neeraj Aryal, Maureen Hattersley, Wenlin Shao, Jamal C. Saeh, Stephen E. Fawell, Ricky W. Johnstone, Lisa Drew, Justin Cidado

Blood (2021) 137 (21): 2947–2957.

https://doi.org/10.1182/blood.2020008528

Published: 2021

Includes: Supplemental data

Journal Articles

Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes

Lauren M Brown, BSc, Hannah Huckstep, BSc, Jarrod Sandow, PhD, Ray C Bartolo, PhD, Nadia Davidson, PhD, Breon Schmidt, BSc, Stefan Bjelosevic, BSc, Ricky W Johnstone, PhD, Alicia Oshlack, PhD, Melissa Davis, PhD, Paul G Ekert

Blood (2018) 132 (Supplement 1): 2628.

https://doi.org/10.1182/blood-2018-99-117844

Published: 2018

Journal Articles

BCOR Regulates Cell Fate Transition, Myeloid Differentiation and Leukaemogenesis

Lev M Kats, PhD, Madison J Kelly, Gareth Gregory, MBBS, PhD FRACP, FRCPA, Ricky W Johnstone, PhD, Stephin J Vervoort, PhD

Blood (2018) 132 (Supplement 1): 3907.

https://doi.org/10.1182/blood-2018-99-117893

Published: 2018

Journal Articles

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Blood (2017) 129 (21): 2882–2895.

https://doi.org/10.1182/blood-2016-05-718171

Published: 2017

Includes: Supplemental data

Journal Articles

Intravital Microscopy Reveals Fundamental Differences in the Interaction of Stem Cells and T Acute Lymphoblastic Leukaemia with the Bone Marrow Microenvironment

Blood (2016) 128 (22): 5199.

https://doi.org/10.1182/blood.V128.22.5199.5199

Published: 2016

Journal Articles

Bigger, Stronger, Faster: Chimeric Antigen Receptor T Cells Are Olympic Killers

Paul J Neeson, BSc, PhD, Alexander James Davenport, BSC, MSc, Joseph A Trapani, Michael Kershaw, PhD, Ryan Cross, H. Miles Prince, MD PhD, Ricky W Johnstone, PhD, David Ritchie, MD PhD, Phil Darcy, Misty R Jenkins

Blood (2016) 128 (22): 814.

https://doi.org/10.1182/blood.V128.22.814.814

Published: 2016

Journal Articles

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

Geoffrey M. Matthews, Parinaz Mehdipour, Leonie A. Cluse, Katrina J. Falkenberg, Eric Wang, Mareike Roth, Fabio Santoro, Eva Vidacs, Kym Stanley, Colin M. House, James R. Rusche, Christopher R. Vakoc, Johannes Zuber, Saverio Minucci, Ricky W. Johnstone

Blood (2015) 126 (21): 2392–2403.

https://doi.org/10.1182/blood-2015-03-632984

Published: 2015

Includes: Supplemental data

Journal Articles

Modelling Resistance to Emerging Epigenetic Therapies

Blood (2014) 124 (21): 3546.

https://doi.org/10.1182/blood.V124.21.3546.3546

Published: 2014

Journal Articles

Id2 represses E2A-mediated activation of IL-10 expression in T cells

Frederick Masson, Margherita Ghisi, Joanna R. Groom, Axel Kallies, Cyril Seillet, Ricky W. Johnstone, Stephen L. Nutt, Gabrielle T. Belz

Blood (2014) 123 (22): 3420–3428.

https://doi.org/10.1182/blood-2014-03-561456

Published: 2014

Journal Articles

Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors

Michael Bots, Inge Verbrugge, Benjamin P. Martin, Jessica M. Salmon, Margherita Ghisi, Adele Baker, Kym Stanley, Jake Shortt, Gert J. Ossenkoppele, Johannes Zuber, Amy R. Rappaport, Peter Atadja, Scott W. Lowe, Ricky W. Johnstone

Blood (2014) 123 (9): 1341–1352.

https://doi.org/10.1182/blood-2013-03-488114

Published: 2014

Includes: Supplemental data

Journal Articles

Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells

Toshihiko Tanno, Yiting Lim, Qiuju Wang, Marta Chesi, P. Leif Bergsagel, Geoff Matthews, Ricky W. Johnstone, Nilanjan Ghosh, Ivan Borrello, Carol Ann Huff, William Matsui

Blood (2014) 123 (5): 725–733.

https://doi.org/10.1182/blood-2013-08-524025

Published: 2014

Includes: Supplemental data

Journal Articles

Class I/II Histone Deacetylase Inhibitors Are a Potential Therapeutic For Notch-1 Driven T Cell Acute Lymphoblastic Leukemia

Michaela Waibel, PhD, Edwin D Hawkins, PhD, Kelly M Ramsbottom, Benjamin P Martin, Ricky W Johnstone, PhD

Blood (2013) 122 (21): 1435.

https://doi.org/10.1182/blood.V122.21.1435.1435

Published: 2013

Journal Articles

Inhibition Of RNA Polymerase I Transcription By CX-5461 As a Therapeutic Strategy For The Cancer-Specific Activation Of p53 In Highly Refractory Haematological Malignancies

Nadine Hein, PhD, Sean O'Brien, Ph.D., Denis Drygin, PhD, Simon J. Harrison, MBBS MRCP (uk) MRCPath (uk) PhD, Amit Khot, MD, FRCPath, MBBS, MRCP, Carleen Cullinane, PhD, Matthews Geoff, PhD, Marta Chesi, PhD, Peter Leif Bergsagel, MD, Johannes Zuber, MD, Scott W. Lowe, Ph.D., Ricky W Johnstone, PhD, Rick Pearson, PhD, Grant A. McArthur, MD, PhD, FRACP, MBBS, Ross D Hannan, PhD

Blood (2013) 122 (21): 3941.

https://doi.org/10.1182/blood.V122.21.3941.3941

Published: 2013

Journal Articles

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance

Fabio Santoro, Oronza A. Botrugno, Roberto Dal Zuffo, Isabella Pallavicini, Geoffrey M. Matthews, Leonie Cluse, Iros Barozzi, Silvia Senese, Lorenzo Fornasari, Simona Moretti, Lucia Altucci, Pier Giuseppe Pelicci, Susanna Chiocca, Ricky W. Johnstone, Saverio Minucci

Blood (2013) 121 (17): 3459–3468.

https://doi.org/10.1182/blood-2012-10-461988

Published: 2013

Includes: Supplemental data

Journal Articles

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

Jake Shortt, Benjamin P. Martin, Andrea Newbold, Katherine M. Hannan, Jennifer R. Devlin, Adele J. Baker, Rachael Ralli, Carleen Cullinane, Clemens A. Schmitt, Maurice Reimann, Michael N. Hall, Meaghan Wall, Ross D. Hannan, Richard B. Pearson, Grant A. McArthur, Ricky W. Johnstone

Blood (2013) 121 (15): 2964–2974.

https://doi.org/10.1182/blood-2012-08-446096

Published: 2013

Includes: Supplemental data

Journal Articles

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma

Stephen R. Mattarollo, Alison C. West, Kim Steegh, Helene Duret, Christophe Paget, Ben Martin, Geoffrey M. Matthews, Jake Shortt, Marta Chesi, P. Leif Bergsagel, Michael Bots, Johannes Zuber, Scott W. Lowe, Ricky W. Johnstone, Mark J. Smyth

Blood (2012) 120 (15): 3019–3029.

https://doi.org/10.1182/blood-2012-04-426643

Published: 2012

Includes: Supplemental data

Journal Articles

E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis

Blood (2012) 120 (4): 822–832.

https://doi.org/10.1182/blood-2011-10-387647

Published: 2012

Includes: Supplemental data

Journal Articles

Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy

Marta Chesi, Geoffrey M. Matthews, Victoria M. Garbitt, Stephen E. Palmer, Jake Shortt, Marcus Lefebure, A. Keith Stewart, Ricky W. Johnstone, P. Leif Bergsagel

Blood (2012) 120 (2): 376–385.

https://doi.org/10.1182/blood-2012-02-412783

Published: 2012

Includes: Supplemental data

Journal Articles

The Pan Histone Deacetylase Inhibitor Panobinostat and the Iso-Selective Inhibitor Romidepsin Reduce Glycoprotein VI Expression and Inhibit Platelet Activation in Response to Collagen Related Peptide

Mark J Bishton, Miles Prince, MD, FRACP, FRCPA, Ricky W Johnstone, PhD, Simon J. Harrison, MBBS MRCP (uk) MRCPath (uk) PhD, Benjamin T. Kile, PhD

Blood (2011) 118 (21): 1154.

https://doi.org/10.1182/blood.V118.21.1154.1154

Published: 2011

Journal Articles

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias

Nadine Hein, PhD, Megan J Bywater, PhD, Kim Stanley, BSc, Inge Verbrugge, PhD, Carlene Cullinane, PhD, Adele Baker, PhD, Hannes Zuber, PhD, Amy Rappaport, PhD, Denis Drygin, PhD, Nanni Huser, PhD, Josh Bliesath, PhD, David M Ryckman, PhD, William G Rice, PhD, Scott W Lowe, PhD, Ricky W Johnstone, PhD, Richard B Pearson, PhD, Grant A. McArthur, MD, PhD, FRACP, MBBS, Ross D Hannan, PhD

Blood (2011) 118 (21): 1548.

https://doi.org/10.1182/blood.V118.21.1548.1548

Published: 2011

NARROW

Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas

Different Classes of ABL1 Fusions Activate Different Downstream Signalling Nodes

BCOR Regulates Cell Fate Transition, Myeloid Differentiation and Leukaemogenesis

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

Intravital Microscopy Reveals Fundamental Differences in the Interaction of Stem Cells and T Acute Lymphoblastic Leukaemia with the Bone Marrow Microenvironment

Bigger, Stronger, Faster: Chimeric Antigen Receptor T Cells Are Olympic Killers

Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies

Modelling Resistance to Emerging Epigenetic Therapies

Id2 represses E2A-mediated activation of IL-10 expression in T cells

Differentiation therapy for the treatment of t(8;21) acute myeloid leukemia using histone deacetylase inhibitors

Growth differentiating factor 15 enhances the tumor-initiating and self-renewal potential of multiple myeloma cells

Class I/II Histone Deacetylase Inhibitors Are a Potential Therapeutic For Notch-1 Driven T Cell Acute Lymphoblastic Leukemia

Inhibition Of RNA Polymerase I Transcription By CX-5461 As a Therapeutic Strategy For The Cancer-Specific Activation Of p53 In Highly Refractory Haematological Malignancies

A dual role for Hdac1: oncosuppressor in tumorigenesis, oncogene in tumor maintenance

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

NKT cell adjuvant-based tumor vaccine for treatment of myc oncogene-driven mouse B-cell lymphoma

E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis

Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy

The Pan Histone Deacetylase Inhibitor Panobinostat and the Iso-Selective Inhibitor Romidepsin Reduce Glycoprotein VI Expression and Inhibit Platelet Activation in Response to Collagen Related Peptide

Inhibition of RNA Polymerase I Transcription by CX-5461 As a Therapeutic Strategy for the Cancer-Specific Activation of p53 in MLL-Rearranged Acute Myeloid Leukemias

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American Society of Hematology

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ASH Publications

American Society of Hematology

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