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Journal Articles

Development of CAR T Cells Targeting U5 snRNP200 for the Treatment of Acute Myeloid and B-Lymphoid Leukemias

Takeshi Fujino, Jennifer Lewis, Bing-Yi Chen, Quinlan Sievers, Winson Cai, Sarah Yoo, Serena Mathew, Sydney Souness, Erin R. Burns, Jasmine S. Um, Elisa De Stanchina, Qing Chang, Besnik Qeriqi, Kevin Chen, PU Zhang, Susan Dewolf, Alexander M. Lewis, Kenyon Weis, Brianna Gipson, Cynthia Castro, Nina Fox, Satoshi Kaito, Alyssa Fronk, Martin Akerman, Omar Abdel-Wahab, Anthony F. Daniyan
Journal: Blood
Blood (2024) 144 (Supplement 1): 371.
https://doi.org/10.1182/blood-2024-204143
Published: 2024
Journal Articles

Overcoming Heterogeneity in AML with a Novel or-Gated Hitcar-1XX Platform

Sascha Haubner, Jorge Mansilla-Soto, Andreina Garcia Angus, Qing Chang, Elisa De Stanchina, Michel Sadelain
Journal: Blood
Blood (2022) 140 (Supplement 1): 865–866.
https://doi.org/10.1182/blood-2022-162579
Published: 2022
Journal Articles

Target Densities in Malignant and Normal Cells Determine CAR T Cell Efficacy and Off-Target Hematotoxicity

Sascha Haubner, Jorge Mansilla-Soto, Sarah Nataraj, Friederike Kogel, Qing Chang, Elisa De Stanchina, Kathryn Fraser, Jae H Park, Xiuyan Wang, Isabelle Rivière, Michel Sadelain
Journal: Blood
Blood (2022) 140 (Supplement 1): 869–870.
https://doi.org/10.1182/blood-2022-162968
Published: 2022
Journal Articles

Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition

Neeta Bala Tannan, Mandana T. Manzari, Laurie Herviou, Mariana Da Silva Ferreira, Connor Hagen, Hiroto Kiguchi, Katia Manova-Todorova, Venkatraman Seshan, Elisa de Stanchina, Daniel A. Heller, Anas Younes
Journal: Blood
Blood (2021) 137 (15): 2057–2069.
https://doi.org/10.1182/blood.2020008017
Published: 2021
Includes: Supplemental data
Journal Articles

Dual Inhibition of MCL1 and BCL2 in Lymphoma Using Tumor Targeted Nanoparticles

Neeta Bala Bala, PhD, Mandana Taghizadeh Manzari, PhD, Mariana Da Silva Ferreira, MSc, Zahra Asgari, Connor Hagen, Venkatraman Seshan, PhD, Elisa de Stanchina, Katia Manova-Todorova, Daniel Heller, Anas Younes, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 305.
https://doi.org/10.1182/blood-2019-130571
Published: 2019
Journal Articles

Generation and Application of T-Cell Lymphoma Patient Derived Tumor Xenograft Models

Danilo Fiore, PhD, Xujun Wang, Inna Khodos, Filomena Di Giacomo, PhD, Marcello Gaudiano, BS, Jude M Phillip, DPhil, Rui Wang, Zhiwei Yang, Michael Ginsberg, Andrew M Intlekofer, MD PhD, Craig B. Thompson, MD, Jon C. Aster, MD PhD, Jia Ruan, MD PhD, Samuel Y. Ng, MDPhD, Eric Jacobsen, MD, Ahmet Dogan, MD PhD, Elisa de Stanchina, Marissa Mattar, Leandro Cerchietti, MD, Rohan Bareja, Olivier Elemento, PhD, Wayne Tam, MD PhD, David M. Weinstock, MD, Shahin Rafii, MD, Steven M. Horwitz, MD, Giorgio Inghirami, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 109.
https://doi.org/10.1182/blood.V130.Suppl_1.109.109
Published: 2017
Journal Articles

Peptidomimetic Blockade of MYB in Acute Myeloid Leukemia

Kavitha Ramaswamy, MD, Lauren Forbes, Fiona C Brown, PhD, Richard Koche, PhD, Tatyana Gindin, MDPhD, Gerard Minuesa, PhD, Michael G. Kharas, PhD, Andrei Krivtsov, PhD, Scott A. Armstrong, MD PhD, Eric Still, Elisa de Stanchina, PhD, Randi Isenhart, Guangwu Guo, Birgit Knoechel, MDPhD, Alex Kentsis, MD PhD
Journal: Blood
Blood (2016) 128 (22): 3945.
https://doi.org/10.1182/blood.V128.22.3945.3945
Published: 2016
Journal Articles

Dual Inhibition of Histone Deacetylases and Phosphoinositide 3-Kinase Enhances Therapeutic Activity Against B Cell Lymphoma

Patrizia Mondello, MD MSc, Enrico Derenzini, MD, Zahra Asgari, John Philip, Elliot J Brea, PhD, Venkatraman E Seshan, PhD, Ronald Hendrickson, PhD, Elisa de Stanchina, PhD, David A Scheinberg, MD PhD, Anas Younes, MD
Journal: Blood
Blood (2016) 128 (22): 293.
https://doi.org/10.1182/blood.V128.22.293.293
Published: 2016
Journal Articles

MYC-Dependent PI3K and MCL-1 Feedbacks Attenuate BET Inhibitors Activity in Diffuse Large B-Cell Lymphoma

Enrico Derenzini, MD PhD, Patrizia Mondello, MD MSc, Yuxuan Liu, PhD, Mary Scallion, Zahra Asgari, John Philip, Patrick Hilden, MS, Hakim Djaballah, PhD, Ouathek Ouerfelli, PhD, Elisa de Stanchina, PhD, Venkatraman Seshan, PhD, Ronald Hendrickson, PhD, Andrew D. Zelenetz, Anas Younes, MD
Journal: Blood
Blood (2016) 128 (22): 294.
https://doi.org/10.1182/blood.V128.22.294.294
Published: 2016
Journal Articles

A Pharmacologically Reversible Epigenomic Signature of Relapse and Chemotherapy Resistance in Anaplastic Large Cell Lymphoma

Heng Pan, BS, Marcello Gaudiano, Fabrizio Tabbo', Elisa de Stanchina, Peter Martin, MD, Olivier Elemento, PhD, Giorgio Inghirami, MD
Journal: Blood
Blood (2016) 128 (22): 3932.
https://doi.org/10.1182/blood.V128.22.3932.3932
Published: 2016
Journal Articles

Janus kinase inhibition by ruxolitinib extends dasatinib- and dexamethasone-induced remissions in a mouse model of Ph+ ALL

Iris Appelmann, Cory D. Rillahan, Elisa de Stanchina, Gregory Carbonetti, Chong Chen, Scott W. Lowe, Charles J. Sherr
Journal: Blood
Blood (2015) 125 (9): 1444–1451.
https://doi.org/10.1182/blood-2014-09-601062
Published: 2015
Includes: Supplemental data
Journal Articles

Improved Efficacy Of Combination Of JAK2 and Hedgehog Inhibitors In Myelofibrosis

Neha Bhagwat, B.S., Matthew D Keller, B.S., Raajit K. Rampal, M.D., Ph.D., Kaitlyn Shank, B.S., Elisa de Stanchina, PhD, Kristine Rose, PhD, Dereck Amakye, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 666.
https://doi.org/10.1182/blood.V122.21.666.666
Published: 2013
Journal Articles

Epigenetic Profiling Of Leukemia Stem Cells In a Model Of TET2/FLT3-Mutant AML

Alan H. Shih, MD PhD, Yanwen Jiang, PhD, Kaitlyn Shank, Suveg Pandey, Agnes Viale, PhD, Yongming Sun, PhD, Nicholas Socci, PhD, Alexander Robertson, PhD, Elisa de Stanchina, PhD, Todd Hricik, Franck Rapaport, PhD, Brittany Woods, Luisa Cimmino, PhD, Laura Barreyro, M.Sc., Ulrich Steidl, MD PhD, Iannis Aifantis, PhD, Ari Melnick, MD, Ross L. Levine, MD
Journal: Blood
Blood (2013) 122 (21): 476.
https://doi.org/10.1182/blood.V122.21.476.476
Published: 2013
Journal Articles

E6AP ubiquitin ligase regulates PML-induced senescence in Myc-driven lymphomagenesis

Kamil Wolyniec, Jake Shortt, Elisa de Stanchina, Yaara Levav-Cohen, Osnat Alsheich-Bartok, Igal Louria-Hayon, Vincent Corneille, Beena Kumar, Simone J. Woods, Stephen Opat, Ricky W. Johnstone, Clare L. Scott, David Segal, Pier Paolo Pandolfi, Stephen Fox, Andreas Strasser, Yong-Hui Jiang, Scott W. Lowe, Sue Haupt, Ygal Haupt
Journal: Blood
Blood (2012) 120 (4): 822–832.
https://doi.org/10.1182/blood-2011-10-387647
Published: 2012
Includes: Supplemental data
Journal Articles

Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis

Priya Koppikar, Omar Abdel-Wahab, Cyrus Hedvat, Sachie Marubayashi, Jay Patel, Aviva Goel, Nicole Kucine, Jeffrey R. Gardner, Andrew P. Combs, Kris Vaddi, Patrick J. Haley, Timothy C. Burn, Mark Rupar, Jacqueline F. Bromberg, Mark L. Heaney, Elisa de Stanchina, Jordan S. Fridman, Ross L. Levine
Journal: Blood
Blood (2010) 115 (14): 2919–2927.
https://doi.org/10.1182/blood-2009-04-218842
Published: 2010
Includes: Supplemental data
Journal Articles

The Novel Human Ph + Acute Lymphoblastic Leukemia Cell Line PhALL3.1 Is Amenable to Retroviral Gene Transfer and Mimics Human Disease Progression in SCID-Beige Mice

Mark G. Frattini, MD, PhD, Elmer Santos, MD, PhD, Mark Lawrence Heaney, MD, PhD, Peter Maslak, MD, Suresh C Jhanwar, PhD, Steven M Larson, MD, Elisa De Stanchina, PhD, Bayard Clarkson, MD, Renier J. Brentjens, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 4875.
https://doi.org/10.1182/blood.V112.11.4875.4875
Published: 2008