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Journal Articles

Two Decade Single Institution Experience Highlights Rare Survivors with Relapsed or Refractory Burkitt Lymphoma

Rabeya Molla, Ellin Berman, Philip Caron, Gerard Donnelly, Lorenzo Falchi, Paul A. Hamlin, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Joseph G Jurcic, Anita Kumar, Jennifer Kimberly Lue, Alison Moskowitz, Colette Owens, Parastoo B Dahi, Maria Lia Palomba, Carol S. Portlock, Gilles Salles, Craig S Sauter, Santosha A. Vardhana, Gunjan L. Shah, David J. Straus, Anas Younes, Anas Younes, Andrew D. Zelenetz, Ariela Noy
Journal: Blood
Blood (2024) 144 (Supplement 1): 6520.
https://doi.org/10.1182/blood-2024-210617
Published: 2024
Journal Articles

Pre-Clinical Evaluation of AZD5492, a Novel CD8-Guided T Cell Engager, for B-Non Hodgkin Lymphoma Indications

Rachel Lawrence, Corinne Cayatte, Macarena Izuzquiza Fernandez, Scott Rata, Thomas Ciucci, Wen Lin, Abigail Lara, Nazli Jafarzadeh, Taylor Foreman, Sterling Payne, Harini Shandilya, Nisha Sambamurthy, Haibin Luo, Richard Stebbings, Simon Dovedi, Gullu Gorgun, Anthony Mato, Saso Cemerski, Mark Cobbold, Anas Younes
Journal: Blood
Blood (2024) 144 (Supplement 1): 959.
https://doi.org/10.1182/blood-2024-198745
Published: 2024
Journal Articles

First Disclosure of AZD9829, a TOP1i-ADC Targeting CD123: Promising Preclinical Activity in AML Models with Minimal Effect on Healthy Progenitors

Dipannita Dutta, Pan Pan, Ryan Fleming, Marcio Andrade-Campos, Elena Belova, Jennifer Wheeler, Patricia Cheung, Paul Santacroce, Casey Daniels, Darrin Sabol, Brad Jakubison, Benedicte Recolin, Andrew Dippel, Margaret Wey, Arthur Shaffer, Edward Rosfjord, Elaine Hurt, Gullu Gorgun, Anas Younes, Puja Sapra
Journal: Blood
Blood (2023) 142 (Supplement 1): 5957.
https://doi.org/10.1182/blood-2023-187642
Published: 2023
Journal Articles

Multi-Cancer Early Detection Test Is Sensitive and Accurate in Detecting Shared DNA Methylation Signal in a Variety of Lymphoid and Plasma Cell Neoplasms

Candace Westgate, Gilles Salles, Stephannie Shih, Margarita Lopatin, Kathryn N. Kurtzman, Katerina Kappes, Oliver Venn, Samir Parekh, Jeffrey M. Venstrom, Anas Younes, Rita Shaknovich
Journal: Blood
Blood (2023) 142 (Supplement 1): 3646.
https://doi.org/10.1182/blood-2023-186481
Published: 2023
Journal Articles

Epigenetic Silencing of MTAP in Hodgkin's Lymphoma Renders It Sensitive to a 2 nd Generation PRMT5 Inhibitor

Jelena Urosevic, James T. Lynch, Stefanie Meyer, Nevin Yusufova, Elizabeth Wiseman, Paul Waring, Ted Hong, Zuleyha Ozen, Haiyun Wang, Lauren Bradshaw, Hannah Tomczak, Ho Man Chan, Ruben Reyes, Susan Critchlow, Anas Younes, Emma Dean
Journal: Blood
Blood (2023) 142 (Supplement 1): 4185.
https://doi.org/10.1182/blood-2023-174445
Published: 2023
Journal Articles

Potentiating antibody-dependent killing of cancers with CAR T cells secreting CD47-SIRPα checkpoint blocker

Megan M. Dacek, Keifer G. Kurtz, Patrick Wallisch, Stephanie A. Pierre, Shireen Khayat, Christopher M. Bourne, Thomas J. Gardner, Kristen C. Vogt, Nica Aquino, Anas Younes, David A. Scheinberg
Journal: Blood
Blood (2023) 141 (16): 2003–2015.
https://doi.org/10.1182/blood.2022016101
Published: 2023
Includes: Supplemental data
Journal Articles

Brentuximab Vedotin Combined with Chemotherapy in Newly Diagnosed, Early-Stage, Unfavorable-Risk Hodgkin Lymphoma: Extended Follow-up with Evaluation of Baseline Metabolic Tumor Volume and PET2

Robert Stuver, Laure Michaud, Carla Casulo, Ranjana H. Advani, Elizabeth L. Budde, Paul M. Barr, Connie Lee Batlevi, Philip C Caron, Louis S. Constine, Savita Dandapani, Pamela Drullinsky, Jonathan W. Friedberg, Clare Grieve, Audrey Hamilton, Paul A. Hamlin, Richard Hoppe, Steven M. Horwitz, Niloufer Khan, Matthew J. Matasar, Ariela Noy, M.Lia Palomba, Heiko Schoder, David J. Straus, Shreya Vemuri, Joachim Yahalom, Joanna C. Yang, Anas Younes, Andrew D. Zelenetz, Craig H. Moskowitz, Anita Kumar, Alison J. Moskowitz
Journal: Blood
Blood (2022) 140 (Supplement 1): 1756–1758.
https://doi.org/10.1182/blood-2022-156382
Published: 2022
Journal Articles

Molecular Profiling across Lymphoma Subtypes Using MSK-Impact Next Generation Sequencing

Connie Lee Batlevi, Esther Drill, Michelle Okwali, Ryan Ptashkin, Philip C Caron, Zachary D. Epstein-Peterson, Lorenzo Falchi, Audrey Hamilton, Paul A. Hamlin, Steven M. Horwitz, Andrew M. Intlekofer, William T. Johnson, Niloufer Khan, Anita Kumar, Jennifer Kimberly Lue, Matthew J. Matasar, Alison J. Moskowitz, Ariela Noy, Colette Owens, Maria Lia Palomba, David J. Straus, Santosha Vardhana, Andrew D. Zelenetz, Maria E. Arcila, Ahmet Dogan, Venkatraman Seshan, Gilles Salles, Ahmet Zehir, Anas Younes
Journal: Blood
Blood (2022) 140 (Supplement 1): 9251–9253.
https://doi.org/10.1182/blood-2022-158783
Published: 2022
Journal Articles

Interim Efficacy Analysis of a Phase II Study Demonstrates Promising Activity of the Combination of Pembrolizumab (PEM) and Entinostat (ENT) in Relapsed and Refractory (R/R) Hodgkin Lymphoma (HL)

David J. Sermer, Santosha Vardhana, Erin Biggar, Alison J. Moskowitz, Erel Joffe, Niloufer Khan, David J. Straus, Anita Kumar, Andrew D. Zelenetz, Steven M. Horwitz, Ariela Noy, Connie Lee Batlevi, Audrey Hamilton, Colette Owens, Matthew J. Matasar, M. Lia Palomba, Christina Y. Lee, Lorenzo Falchi, William T. Johnson, Heiko Schoder, Ahmet Dogan, Tira Bunyaviroch, Venkatraman Seshan, Gilles Salles, Anas Younes, Gottfried von Keudell
Journal: Blood
Blood (2021) 138 (Supplement 1): 2447.
https://doi.org/10.1182/blood-2021-154226
Published: 2021
Journal Articles

TP53 Mutations and RNA Binding Protein Musashi 2 Drive Resistance to PRMT5-Targeted Therapy in B-Cell Lymphoma

Ingrid Tatiana Erazo, Chiara M Evans, Daniel Zakheim, Karen L Chu, Olena Barbash, Alice Yunsi Refermat, Connie Lee Batlevi, Anas Younes, Michael G Kharas
Journal: Blood
Blood (2021) 138 (Supplement 1): 788.
https://doi.org/10.1182/blood-2021-151280
Published: 2021
Journal Articles

PK and PD Assessment of BET Inhibitor Pelabresib (CPI-0610) in Patients with Relapsed or Refractory Lymphoma: Findings from a Phase 1 Study

Kristie A. Blum, Jeffrey G. Supko, Michael Maris, Ian W. Flinn, Andre H. Goy, Anas Younes, Suresh Bobba, Adrian Senderowicz, Sergey Efuni, Ronda Rippley, Jeremy S. Abramson
Journal: Blood
Blood (2021) 138 (Supplement 1): 1202.
https://doi.org/10.1182/blood-2021-150852
Published: 2021
Journal Articles

Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition

Neeta Bala Tannan, Mandana T. Manzari, Laurie Herviou, Mariana Da Silva Ferreira, Connor Hagen, Hiroto Kiguchi, Katia Manova-Todorova, Venkatraman Seshan, Elisa de Stanchina, Daniel A. Heller, Anas Younes
Journal: Blood
Blood (2021) 137 (15): 2057–2069.
https://doi.org/10.1182/blood.2020008017
Published: 2021
Includes: Supplemental data
Journal Articles

Clinical characteristics and outcomes of extranodal stage I diffuse large B-cell lymphoma in the rituximab era

Sabela Bobillo, Erel Joffe, Jessica A. Lavery, David Sermer, Paola Ghione, Ariela Noy, Philip C. Caron, Audrey Hamilton, Paul A. Hamlin, Steven M. Horwitz, Anita Kumar, Matthew J. Matasar, Alison Moskowitz, Collette N. Owens, M. Lia Palomba, Connie L. Batlevi, David Straus, Gottfried von Keudell, Andrew D. Zelenetz, Joachim Yahalom, Ahmet Dogan, Venkatraman E. Seshan, Anas Younes
Journal: Blood
Blood (2021) 137 (1): 39–48.
https://doi.org/10.1182/blood.2020005112
Published: 2021
Includes: Supplemental data
Journal Articles

Recil 2017 Criteria Demonstrated Similar Prognostic Value and Detected a Comparable Treatment Difference between Obinutuzumab- and Rituximab-Chemotherapy Compared with Cheson 2007 and Lugano 2014 Criteria in Patients with Previously Untreated Advanced-Stage Follicular Lymphoma

Lale Kostakoglu, MD MPH, Andrew Davies, MD PhD, Michael Herold, Wolfgang Hiddemann, Robert Marcus, Judith Trotman, FRACP, Andrea Knapp, Federico Mattiello, Tina G Nielsen, Deniz Sahin, Carol Ward, Anas Younes
Journal: Blood
Blood (2020) 136 (Supplement 1): 25–26.
https://doi.org/10.1182/blood-2020-134784
Published: 2020
Journal Articles

Brentuximab Vedotin with Chemotherapy for Patients with Previously Untreated, Stage III/IV Classical Hodgkin Lymphoma: 5-Year Update of the ECHELON-1 Study

David J. Straus, MD, Monika Dlugosz-Danecka, MD PhD, Joseph M. Connors, MD, Árpád Illés, MD PhD, Marco Picardi, MD, Ewa Lech-Marańda, MD PhD, Tatyana Feldman, Piotr Smolewski, MD PhD, Kerry J. Savage, MDMSc, Nancy L. Bartlett, MD, Jan Walewski, MD, Radhakrishnan Ramchandren, MD, Pier Luigi Zinzani, MD, Martin Hutchings, MD PhD, Javier Munoz, MD, Won Seog Kim, MD PhD, Ranjana Advani, MD, Stephen M. Ansell, MD PhD, Anas Younes, Andrea Gallamini, Rachael Liu, PhD, Meredith Little, MPH, Keenan Fenton, Michelle A. Fanale, MD, John A. Radford, MD FMedSci
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–28.
https://doi.org/10.1182/blood-2020-137089
Published: 2020
Journal Articles

R-CHOP Versus R-Bendamustine with or without Rituximab Maintenance in Newly Diagnosed Follicular Lymphoma Patients with High SUV at Baseline PET

Patrizia Mondello, MDPhDMSc, Paolo Strati, MD, Reid W Merryman, MD, Erel Joffe, MD MSc, Marco Ruella, MD, Venkatraman Seshan, PhD, Frederique St Pierre, Ajay Major, MDMBA, Priyanka Pophali, MD, Megan Fiasconaro, Carrie I Ho, MD, Eleanor Neal, Chao-Ming Lai, Gabriela Spilberg, MD, Saurabh Rajguru, MD, Jakub Svoboda, MD, Thomas E. Witzig, MD, Sonali M. Smith, MD, Philippe Armand, MD PhD, Loretta J. Nastoupil, MD, Stephen M. Ansell, MD PhD, Andrew D Zelenetz, MD PhD, Anas Younes, Gilles Salles
Journal: Blood
Blood (2020) 136 (Supplement 1): 39–40.
https://doi.org/10.1182/blood-2020-136438
Published: 2020
Journal Articles

Interim Analysis from a Prospective Multicenter Study of Next-Generation Sequencing Minimal Residual Disease Assessment and CT Monitoring for Surveillance after Frontline Treatment in Diffuse Large B-Cell Lymphoma

Anita Kumar, MD, Jason Westin, MD, Stephen J Schuster, MD, Grzegorz S. Nowakowski, MD, Izidore S. Lossos, MD, Connie Lee Batlevi, MDPhD, Philip Caron, MD PhD, Pamela Drullinsky, MD, John Gerecitano, MD PhD, Audrey Hamilton, MD, Paul A. Hamlin, MD, Steven M. Horwitz, MD, Allison P. Jacob, Erel Joffe, MD MSc, Ashlee Joseph, Gottfried R. von Keudell, MD PhD, Leana Laraque, BA, Oscar B Lahoud, MD, Matthew J Matasar, MD, Craig H. Moskowitz, MD, Chelsea D Mullins, BS, Ariela Noy, MD, Colette Owens, MD, Maria Lia Palomba, Carol S. Portlock, MD, Ildefonso Rodriguez-Rivera, MD, Gilles Salles, MDPhD, Venkatraman Seshan, PhD, David J. Straus, MD, Shreya Vemuri, Anas Younes, Andrew D Zelenetz, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 46–47.
https://doi.org/10.1182/blood-2020-138889
Published: 2020
Journal Articles

Safety, Pharmacokinetics and Activity of CA-4948, an IRAK4 Inhibitor, for Treatment of Patients with Relapsed or Refractory Hematologic Malignancies: Results from the Phase 1 Study

Grzegorz S. Nowakowski, MD, Lori A. Leslie, MD, Anas Younes, Allison C. Rosenthal, D.O., Matthew A. Lunning, DO, FACP, Krish Patel, MD, Daniel J. Landsburg, MD, Elizabeth Martinez, PhD DHSC, MSN, Reinhard von Roemeling, MD, Christopher Lieberman, Han W. Tun, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 44–45.
https://doi.org/10.1182/blood-2020-140857
Published: 2020
Journal Articles

Frontline Sequential Immunochemotherapy Plus Lenalidomide for Mantle Cell Lymphoma Incorporating MRD Evaluation: Phase II, Investigator-Initiated, Single-Center Study

Zachary D. Epstein-Peterson, MD, Connie Lee Batlevi, MDPhD, Philip Caron, MD PhD, Ahmet Dogan, MD PhD, Pamela Drullinsky, MD, John Gerecitano, MD PhD, Audrey Hamilton, MD, Paul A. Hamlin, MD, Caleb Ho, MD, Allison P. Jacob, Leana Laraque, BA, Matthew J Matasar, MD, Alison J. Moskowitz, MD, Craig H. Moskowitz, MD, Chelsea D Mullins, BS, Colette Owens, MD, Gilles Salles, Heiko Schöder, MD, David J. Straus, MD, Anas Younes, Andrew D Zelenetz, MD PhD, Anita Kumar, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 11–12.
https://doi.org/10.1182/blood-2020-136565
Published: 2020
Journal Articles

Brentuximab vedotin with chemotherapy for stage III/IV classical Hodgkin lymphoma: 3-year update of the ECHELON-1 study

Clinical Trials & Observations
David J. Straus, Monika Długosz-Danecka, Sergey Alekseev, Árpád Illés, Marco Picardi, Ewa Lech-Maranda, Tatyana Feldman, Piotr Smolewski, Kerry J. Savage, Nancy L. Bartlett, Jan Walewski, Radhakrishnan Ramchandren, Pier Luigi Zinzani, Martin Hutchings, Joseph M. Connors, John Radford, Javier Munoz, Won Seog Kim, Ranjana Advani, Stephen M. Ansell, Anas Younes, Harry Miao, Rachael Liu, Keenan Fenton, Andres Forero-Torres, Andrea Gallamini
Journal: Blood
Blood (2020) 135 (10): 735–742.
https://doi.org/10.1182/blood.2019003127
Published: 2020
Includes: Supplemental data