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David Sermer
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Journal Articles

Escalating Doses of AZD0486, a Novel CD19xCD3 T-Cell Engager, Result in High Complete Remissions with Rapid Clearance of Minimal Residual Disease in Patients with Relapsed/Refractory Follicular Lymphoma

Jing-Zhou Hou, Ranjit Nair, Ryan Jacobs, Tae Min Kim, Seok-Goo Cho, Dai Maruyama, Sumana Devata, Yazeed Sawalha, Dok Hyun Yoon, Constantine S. Tam, Koji Izutsu, Matthew Matasar, Don A. Stevens, Aravind Ramakrishnan, Denise Brennan, Xu Zhu, Robin Lesley, Yasuhiro Oki, David Sermer, Sameh Gaballa
Journal: Blood
Blood (2024) 144 (Supplement 1): 341.
https://doi.org/10.1182/blood-2024-193589
Published: 2024
Journal Articles

Final Response and Survival Results from a Phase II Trial of Pembrolizumab and Entinostat in Relapsed/Refractory Hodgkin Lymphoma

Robert Stuver, Santosha A. Vardhana, Nivetha Ganesan, Alexander P. Boardman, Philip Caron, Tiffany Chang, Kevin A. David, Zachary D. Epstein-Peterson, Lorenzo Falchi, Paola Ghione, Paul A. Hamlin, Francisco Hernandez-Ilizaliturri, Steven Horwitz, Andrew M. Intlekofer, William T. Johnson, Reem Karmali, Jennifer Kimberly Lue, Anita Kumar, Efrat Luttwak, Neena Mahajan, Amira Marouf, Ariela Noy, Colette Owens, Maria Lia Palomba, Gilles Salles, Heiko Schoder, David Sermer, Venkatraman Seshan, Raphael E. Steiner, Pallawi Torka, Andrew D. Zelenetz, Gottfried von Keudell, Alison Moskowitz
Journal: Blood
Blood (2024) 144 (Supplement 1): 3053.
https://doi.org/10.1182/blood-2024-210053
Published: 2024
Journal Articles

Evaluation of AZD0486, a Novel CD19xCD3 T-Cell Engager, in Relapsed/Refractory Diffuse Large B-Cell Lymphoma in an Ongoing First-in-Human Phase 1 Study: High Complete Responses Seen in CAR-T-Naive and CAR-T-Exposed Patients

Sameh Gaballa, Jing-Zhou Hou, Sumana Devata, Seok-Goo Cho, Ranjit Nair, Dok Hyun Yoon, Ryan Jacobs, Koji Izutsu, Don A. Stevens, Dai Maruyama, Constantine S. Tam, Yazeed Sawalha, Aravind Ramakrishnan, Matthew Matasar, Denise Brennan, Sue Zhu, Robin Lesley, Yasuhiro Oki, David Sermer, Tae Min Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 868.
https://doi.org/10.1182/blood-2024-193681
Published: 2024
Journal Articles

Exposure-Response Analysis and Quantitative Systems Pharmacology Modeling for Optimal RP2D Selection of AZD0486 in Follicular Lymphoma Patients

Xu (Sue) Zhu, Damilola Olabode, Massimo Lai, Cesar Pichardo-Almarza, Kevin Smart, Denise Brennan, David Sermer, Robin Lesley
Journal: Blood
Blood (2024) 144 (Supplement 1): 2794.
https://doi.org/10.1182/blood-2024-197995
Published: 2024
Journal Articles

Ibrutinib and venetoclax as primary therapy in symptomatic, treatment-naïve Waldenström macroglobulinemia

Clinical Trials & Observations
Jorge J. Castillo, Andrew R. Branagan, David Sermer, Catherine A. Flynn, Kirsten Meid, Megan Little, Katherine Stockman, Timothy White, Alexa Canning, Maria L. Guerrera, Amanda Kofides, Shirong Liu, Xia Liu, Kris Richardson, Nicholas Tsakmaklis, Christopher J. Patterson, Zachary R. Hunter, Steven P. Treon, Shayna Sarosiek
Journal: Blood
Blood (2024) 143 (7): 582–591.
https://doi.org/10.1182/blood.2023022420
Published: 2024
Includes: Supplemental data
Journal Articles

Double Step-up Dosing (2SUD) Regimen Mitigates Severe Icans and CRS While Maintaining High Efficacy in Subjects with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (NHL) Treated with AZD0486, a Novel CD19xCD3 T-Cell Engager (TCE): Updated Safety and Efficacy Data from the Ongoing First-in-Human (FIH) Phase 1 Trial

Sameh Gaballa, Ranjit Nair, Ryan W Jacobs, Sumana Devata, Seok-Goo Cho, Don A. Stevens, Dok Hyun Yoon, Nirav N. Shah, Denise Brennan, Jason Law, Robert Chen, David Sermer, Robin Lesley, Ben Buelow, Alessandra Forcina, Jing-Zhou Hou
Journal: Blood
Blood (2023) 142 (Supplement 1): 1662.
https://doi.org/10.1182/blood-2023-174668
Published: 2023
Journal Articles

Clinical characteristics and outcomes of extranodal stage I diffuse large B-cell lymphoma in the rituximab era

Sabela Bobillo, Erel Joffe, Jessica A. Lavery, David Sermer, Paola Ghione, Ariela Noy, Philip C. Caron, Audrey Hamilton, Paul A. Hamlin, Steven M. Horwitz, Anita Kumar, Matthew J. Matasar, Alison Moskowitz, Collette N. Owens, M. Lia Palomba, Connie L. Batlevi, David Straus, Gottfried von Keudell, Andrew D. Zelenetz, Joachim Yahalom, Ahmet Dogan, Venkatraman E. Seshan, Anas Younes
Journal: Blood
Blood (2021) 137 (1): 39–48.
https://doi.org/10.1182/blood.2020005112
Published: 2021
Includes: Supplemental data
Journal Articles

Central Nervous System Prophylaxis with High-Dose Intravenous Methotrexate or Intrathecal Chemotherapy in Patients with Diffuse Large B-Cell Lymphoma and High-Risk of CNS Relapse Treated in the Rituximab Era

Sabela Bobillo, MD, Erel Joffe, MDMSc, Venkatraman Seshan, PhD, Ariela Noy, MD, Steven M. Horwitz, MD, M. Lia Palomba, MD, Matthew J Matasar, MD, David J. Straus, MD, Paul A. Hamlin, MD, Connie Lee Batlevi, MD PhD, Paola Ghione, MD, David Sermer, MD, Alison J. Moskowitz, MD, Audrey Hamilton, MD, Philip Caron, MD PhD, Colette Owens, MD, Gottfried R. von Keudell, MD PhD, Ahmet Dogan, MD PhD, Andrew D. Zelenetz, MD PhD, Anas Younes, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1619.
https://doi.org/10.1182/blood-2019-131435
Published: 2019