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Journal Articles

Surovatamig (AZD0486), a CD19xCD3 T-cell engager (TCE), demonstrates high rate of minimal residual disease (MRD)–Negative complete responses in Relapsed/Refractory (R/R) diffuse large B-cell lymphoma (DLBCL), including in patients who previously progressed on CD20 TCE and CD19 CAR T-cell therapies

Free
Tae Min Kim, Jing-Zhou Hou, Sameh Gaballa, Ranjit Nair, Dai Maruyama, Koji Izutsu, Sumana Devata, Dok Hyun Yoon, Won-Seog Kim, Yazeed Sawalha, Ryan Jacobs, Eliza Hawkes, Ming-Chung Wang, Constantine Tam, Don Stevens, Hisayuki Yokoyama, Jin Seok Kim, Matthew Matasar, Aravind Ramakrishnan, Denise Brennan, David Sermer, Robin Lesley, Xu (Sue) Zhu, Mihail Obrocea, Seok-Goo Cho
Journal: Blood
Blood (2025) 146 (Supplement 1): 5514.
https://doi.org/10.1182/blood-2025-5514
Published: 2025
Journal Articles

LV20.19 CAR T cells for methotrexate relapsed/refractory primary or secondary CNS lymphoma with parenchymal involvement

Free
Ashley Dunton, Adam Kidwell, Jennifer Connelly, Jenna Heffernan, Tyce Kearl, Bryon Johnson, Anthony Stillwell, Sumana Devata, Kaitlin Annunzio, Peiman Hematti, Mehdi Hamadani, Nirav Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 4164.
https://doi.org/10.1182/blood-2025-4164
Published: 2025
Journal Articles

Split dose R-CHOP mitigates toxicity while preserving dose intensity and response in frail elderly patients with diffuse large B cell lymphoma (DLBCL) - a Wisconsin oncology network (WON) study

Free
Christopher Fletcher, Aniko Szabo, Sumana Devata, Vaishalee Kenkre, Priyanka Pophali, Luke Zurbriggen, Julie Chang, Katina Deshong, Mitch Howard, Mariah Endres, Joel Pollen, Esta Konkol, Walter Longo, Mehdi Hamadani, Timothy Fenske, Saurabh Rajguru, Nirav Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 1964.
https://doi.org/10.1182/blood-2025-1964
Published: 2025
Journal Articles

Optimizing the manufacturing and delivery of LV20.19 CAR T cells for relapsed, refractory DLBCL and FL

Free
Nirav Shah, Maria Poimenidou, Adam Kidwell, Aniko Szabo, Tyce Kearl, Bryon Johnson, Anthony Stillwell, Sumana Devata, Kaitlin Annunzio, Rimas Orentas, Walter Longo, Timothy Fenske, Peiman Hematti, Michael Dwinell, Mehdi Hamadani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2401.
https://doi.org/10.1182/blood-2025-2401
Published: 2025
Journal Articles

Rituximab and epcoritamab as first-line therapy for patients with high-tumor burden follicular lymphoma: Results of a multicenter phase II trial

Free
Reid Merryman, Danielle Wallace, Robert Redd, Heather Walker, Rafaella Tringale, Vanessa Kats, Siri Sagedahl, Ioulia Vogiatzi, Mingzeng Zhang, Emily Sumpena, Weihsin Chuan, Audrey Sigmund, Inhye Ahn, Amy Bessnow, Jennifer R. Brown, Jennifer Crombie, Matthew S Davids, David Fisher, Cynthia Hahn, Eric Jacobsen, Caron Jacobson, Austin Kim, Ann LaCasce, Oreofe Odejide, Erin Parry, David Qualls, Christine Ryan, Aswin Sekar, Sumana Devata, Carla Casulo, Kami Maddocks, Mark Murakami, Philippe Armand, Yazeed Sawalha
Journal: Blood
Blood (2025) 146 (Supplement 1): 464.
https://doi.org/10.1182/blood-2025-464
Published: 2025
Journal Articles

Three-year follow-up of the Phase 1 first-in-human study investigating surovatamig, a novel CD19xCD3 T-cell engager, in patients with Relapsed/Refractory (R/R) follicular lymphoma (FL)

Free
Jing-Zhou Hou, Tae Min Kim, Seok-Goo Cho, Sameh Gaballa, Ranjit Nair, Koji Izutsu, Sumana Devata, Dok Hyun Yoon, Won-Seog Kim, Yazeed Sawalha, Ryan Jacobs, Eliza Hawkes, Ming-Chung Wang, Constantine Tam, Don Stevens, Hisayuki Yokoyama, Jin Seok Kim, Matthew Matasar, Aravind Ramakrishnan, Denise Brennan, David Sermer, Robin Lesley, Mihail Obrocea, Dai Maruyama
Journal: Blood
Blood (2025) 146 (Supplement 1): 1005.
https://doi.org/10.1182/blood-2025-1005
Published: 2025
Journal Articles

Split-Dose R-CHOP for Older Patients with Treatment Naïve DLBCL

Free
Adam Kidwell, Fateeha Furqan, Emilie Aschenbrenner, Walter Longo, Sumana Devata, Mehdi Hamadani, Timothy S. Fenske, Nirav N. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 2374.
https://doi.org/10.1182/blood-2024-203974
Published: 2024
Journal Articles

CNS Status at Diagnosis Can Identify Acute Myeloid Leukemia Patients with Poor Induction Outcomes

Free
Kristine Broge-Reynen, Emily Giever, Aniko Szabo, Ryan Conrardy, Nicole M Held, Laura C. Michaelis, Lyndsey Runaas, Sameem Abedin, Guru Subramanian Guru Murthy, Karen-Sue Carlson, Ravi Kishore Narra, Sumana Devata, Sheila Swartz, Valarie Ehrlich, Mary Rodgers, Allison Johnson, Ehab L. Atallah
Journal: Blood
Blood (2024) 144 (Supplement 1): 5173.
https://doi.org/10.1182/blood-2024-208834
Published: 2024
Journal Articles

Evaluation of AZD0486, a Novel CD19xCD3 T-Cell Engager, in Relapsed/Refractory Diffuse Large B-Cell Lymphoma in an Ongoing First-in-Human Phase 1 Study: High Complete Responses Seen in CAR-T-Naive and CAR-T-Exposed Patients

Free
Sameh Gaballa, Jing-Zhou Hou, Sumana Devata, Seok-Goo Cho, Ranjit Nair, Dok Hyun Yoon, Ryan Jacobs, Koji Izutsu, Don A. Stevens, Dai Maruyama, Constantine S. Tam, Yazeed Sawalha, Aravind Ramakrishnan, Matthew Matasar, Denise Brennan, Sue Zhu, Robin Lesley, Yasuhiro Oki, David Sermer, Tae Min Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 868.
https://doi.org/10.1182/blood-2024-193681
Published: 2024
Journal Articles

Escalating Doses of AZD0486, a Novel CD19xCD3 T-Cell Engager, Result in High Complete Remissions with Rapid Clearance of Minimal Residual Disease in Patients with Relapsed/Refractory Follicular Lymphoma

Free
Jing-Zhou Hou, Ranjit Nair, Ryan Jacobs, Tae Min Kim, Seok-Goo Cho, Dai Maruyama, Sumana Devata, Yazeed Sawalha, Dok Hyun Yoon, Constantine S. Tam, Koji Izutsu, Matthew Matasar, Don A. Stevens, Aravind Ramakrishnan, Denise Brennan, Xu Zhu, Robin Lesley, Yasuhiro Oki, David Sermer, Sameh Gaballa
Journal: Blood
Blood (2024) 144 (Supplement 1): 341.
https://doi.org/10.1182/blood-2024-193589
Published: 2024
Journal Articles

Double Step-up Dosing (2SUD) Regimen Mitigates Severe Icans and CRS While Maintaining High Efficacy in Subjects with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (NHL) Treated with AZD0486, a Novel CD19xCD3 T-Cell Engager (TCE): Updated Safety and Efficacy Data from the Ongoing First-in-Human (FIH) Phase 1 Trial

Free
Sameh Gaballa, Ranjit Nair, Ryan W Jacobs, Sumana Devata, Seok-Goo Cho, Don A. Stevens, Dok Hyun Yoon, Nirav N. Shah, Denise Brennan, Jason Law, Robert Chen, David Sermer, Robin Lesley, Ben Buelow, Alessandra Forcina, Jing-Zhou Hou
Journal: Blood
Blood (2023) 142 (Supplement 1): 1662.
https://doi.org/10.1182/blood-2023-174668
Published: 2023
Journal Articles

Real-World Experience with RTOG 0227 Induction for First Line Therapy of Primary CNS Lymphoma (PCNSL)

Free
Ramsha Ahmed, Precious Anyanwu, Nirav N. Shah, Mehdi Hamadani, Walter Longo, Sumana Devata, Julie Pruett, Jennifer Connelly, Joseph Bovi, Malika Siker, Christopher Schultz, Timothy S. Fenske
Journal: Blood
Blood (2023) 142 (Supplement 1): 3122.
https://doi.org/10.1182/blood-2023-190961
Published: 2023
Journal Articles

Interim Results of the Phase 1 Study of Tnb-486, a Novel CD19xCD3 T-Cell Engager, in Patients with Relapsed/Refractory (R/R) B-NHL

Free
Jing-Zhou Hou, Ryan Jacobs, Seok-Goo Cho, Sumana Devata, Sameh Gaballa, Dok Hyun Yoon, Don A. Stevens, Jin Seok Kim, Ben Buelow, Ranjit Nair
Journal: Blood
Blood (2022) 140 (Supplement 1): 1474–1475.
https://doi.org/10.1182/blood-2022-166385
Published: 2022
Journal Articles

A phase 1b study of AFM13 in combination with pembrolizumab in patients with relapsed or refractory Hodgkin lymphoma

Free
Clinical Trials & Observations
Nancy L. Bartlett, Alex F. Herrera, Eva Domingo-Domenech, Amitkumar Mehta, Andres Forero-Torres, Ramon Garcia-Sanz, Philippe Armand, Sumana Devata, Antonia Rodriguez Izquierdo, Izidore S. Lossos, Craig Reeder, Taimur Sher, Robert Chen, Sylvia E. Schwarz, Leila Alland, Andras Strassz, Kim Prier, Cassandra Choe-Juliak, Stephen M. Ansell
Journal: Blood
Blood (2020) 136 (21): 2401–2409.
https://doi.org/10.1182/blood.2019004701
Published: 2020
Includes: Supplemental data
Journal Articles

The DIAL Study (Dual Immunomodulation in Aggressive Lymphoma): A Randomized Phase 2 Study of CDX-1127 (Varlilumab) in Combination with Nivolumab in Patients with Relapsed or Refractory Aggressive B-Cell Lymphomas (NCI 10089 / NCT03038672)

Free
Jose C Villasboas, MD, Craig B. Reeder, MD, Han W. Tun, MD, Nancy L Bartlett, MD, Elad Sharon, MD MPH, Betsy Laplant, MS, Alex A Adjei, MD PhD, Justin Kline, MD, Francisco J. Hernandez-Ilizaliturri, MD, Farrukh T. Awan, MD, Sumana Devata, MD, Aleksandr Lazaryan, MDPhDMPH, Lawrence E Morris, MD, Stephen M Ansell, MD PhD, Catherine Diefenbach, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1591.
https://doi.org/10.1182/blood-2019-130449
Published: 2019
Journal Articles

Final Results of Phase 1/1b Study of Tenalisib, Dual PI3K δ/γ Inhibitor in Patients with Relapsed/Refractory T-Cell Lymphoma

Free
Swaminathan P. Iyer, MD, Brad M. Haverkos, MDMPH,MS, Jasmine Zain, MD, Radhakrishnan Ramchandren, MD, Mary Jo Lechowicz, MD, Sumana Devata, MD, Neil Korman, MD, Lauren C. Pinter-Brown, MD, Kasi Viswanath Routhu, PhD, Prajak Barde, MD, Ajit Mohanchandran Nair, PhD, Auris Huen, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2831.
https://doi.org/10.1182/blood-2019-123954
Published: 2019
Journal Articles

Ruxolitinib Is Active and Well Tolerated in Adult Patients with Secondary Hemophagocytic Lymphohistiocytosis: Preliminary Results of an Ongoing, Open-Label, Single Center Study

Free
Fares Alsawah, MD BS, MS, Samuel A. Merrill, MD PhD, Paula L. Bockenstedt, MD, Erica L. Campagnaro, MD, Sumana Devata, MD, Scott D. Gitlin, MD, Mark S Kaminski, MD, Alice M. Cusick, MD, Tycel J. Phillips, MD, Suman L. Sood, MD, Moshe Talpaz, MD, Albert Thomas Quiery, MD, Philip S Boonstra, PhD, Asra Z. Ahmed, MD, Ryan A. Wilcox, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1119.
https://doi.org/10.1182/blood-2018-99-116854
Published: 2018
Journal Articles

Pooled Safety Analysis and Efficacy of Tenalisib (RP6530), a PI3Kδ/γ Inhibitor, in Patients with Relapsed/Refractory Lymphoid Malignancies

Free
Swami P. Iyer, MD, Auris Huen, MD, Andres J M Ferreri, MD, Bradley M. Haverkos, MD MPH, MS, Jasmine M. Zain, MD, Radhakrishnan Ramchandren, MD, Mary Jo Lechowicz, MD, Sumana Devata, MD, Neil Korman, MD, Lauren C. Pinter-Brown, MD, Richard Delarue, MD, Kasi V Routhu, PhD, Prajak Barde, MD, Ajit M Nair, PhD, Carmelo Carlo-Stella, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2925.
https://doi.org/10.1182/blood-2018-99-112757
Published: 2018
Journal Articles

A Phase 1b Study Investigating the Combination of the Tetravalent Bispecific NK Cell Engager AFM13 and Pembrolizumab in Patients with Relapsed/Refractory Hodgkin Lymphoma after Brentuximab Vedotin Failure: Updated Safety and Efficacy Data

Free
Nancy L. Bartlett, MD, Robert W. Chen, MD, Eva Domingo-Domenech, MD, Andres Forero-Torres, MD, Ramon Garcia-Sanz, MD PhD, Philippe Armand, MD PhD, Sumana Devata, MD, Antonia Rodriguez Izquierdo, MD, Izidore S. Lossos, MD, Craig B. Reeder, MD, Taimur Sher, MD, Cassandra Choe-Juliak, MD MS, Kim Prier, Sylvia Schwarz, PhD, Andras Strassz, MD, Leila Alland, MD, Stephen M. Ansell, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1620.
https://doi.org/10.1182/blood-2018-99-118506
Published: 2018
Journal Articles

Multicenter Retrospective Study of Features and Outcomes of Patients with Intravascular DLBCL Treated at Academic Institutions within the United States

Free
Marcus Geer, MD, Maryann Shango, MD, Brian G. Till, MD, Stephen D. Smith, MD, Hashim Abbas, MD, Brian T. Hill, MD PhD, Jason Kaplan, MD, Paul M. Barr, MD, Paolo Caimi, MD, Deborah M. Stephens, DO, Emily Lin, MD, Alex F. Herrera, MD, Evan Rosenbaum, MD, Jennifer E Amengual, MD, Emily Roberts, Philip S Boonstra, PhD, Sumana Devata, MD, Ryan A. Wilcox, MD, Mark S Kaminski, MD, Tycel J. Phillips, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 377.
https://doi.org/10.1182/blood.V130.Suppl_1.377.377
Published: 2017