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Tyce Kearl
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Journal Articles

LV20.19 CAR T cells for methotrexate relapsed/refractory primary or secondary CNS lymphoma with parenchymal involvement

Free
Ashley Dunton, Adam Kidwell, Jennifer Connelly, Jenna Heffernan, Tyce Kearl, Bryon Johnson, Anthony Stillwell, Sumana Devata, Kaitlin Annunzio, Peiman Hematti, Mehdi Hamadani, Nirav Shah
Journal: Blood
Blood (2025) 146 (Supplement 1): 4164.
https://doi.org/10.1182/blood-2025-4164
Published: 2025
Journal Articles

Optimizing the manufacturing and delivery of LV20.19 CAR T cells for relapsed, refractory DLBCL and FL

Free
Nirav Shah, Maria Poimenidou, Adam Kidwell, Aniko Szabo, Tyce Kearl, Bryon Johnson, Anthony Stillwell, Sumana Devata, Kaitlin Annunzio, Rimas Orentas, Walter Longo, Timothy Fenske, Peiman Hematti, Michael Dwinell, Mehdi Hamadani
Journal: Blood
Blood (2025) 146 (Supplement 1): 2401.
https://doi.org/10.1182/blood-2025-2401
Published: 2025
Journal Articles

Intelligent bispecific BCMA-CD24 CAR-T cells for precision navigation and elimination of multiple myeloma

Free
Shijing Wang, Bin Sun, Ali Ishaq, Deepak Parashar, Sridhar Rao, Tyce Kearl, Jing Dong, Peiman Hematti, Siegfried Janz, Binod Dhakal, Fumou Sun
Journal: Blood
Blood (2025) 146 (Supplement 1): 800.
https://doi.org/10.1182/blood-2025-800
Published: 2025
Journal Articles

Cell-free CAR therapy: BCMA-CAR-T cell-derived exosomes exhibit potent anti-myeloma activity

Free
Bin Sun, Shijing Wang, Ali Ishaq, Deepak Parashar, Sridhar Rao, Tyce Kearl, Jing Dong, Peiman Hematti, Siegfried Janz, Binod Dhakal, Fumou Sun
Journal: Blood
Blood (2025) 146 (Supplement 1): 2159.
https://doi.org/10.1182/blood-2025-2159
Published: 2025
Journal Articles

CAR-T with ICOS costimulation lacks therapeutic efficacy in patient due to strong trogocytosis and failure of expansion

Free
Yongxia Wu, Allison Pugel, Katie Palen, Peiman Hematti, Tyce Kearl, Rimas Orentas, Timothy Fenske, Mehdi Hamadani, Walter Longo, Bryon Johnson, Nirav Shah, Xue-Zhong Yu
Journal: Blood
Blood (2025) 146 (Supplement 1): 2346.
https://doi.org/10.1182/blood-2025-2346
Published: 2025
Journal Articles

Cytogenetic Abnormalities Following CAR T Cell Therapy for B-Cell Malignancies

Free
Na Hyun Kim, Fatima Khamissi, Kathleen Bone, Nathan Kopp, Walter Longo, Bryon D. Johnson, Tyce Kearl, Peiman Hematti, Mehdi Hamadani, Timothy S. Fenske, Nirav N. Shah
Journal: Blood
Blood (2024) 144 (Supplement 1): 3459.
https://doi.org/10.1182/blood-2024-205752
Published: 2024
Journal Articles

Phase 1 Study of Trispecific Anti-CD20, Anti-CD19, Anti-CD22 (CAR20.19.22) T Cells for Relapsed, Refractory B-Cell Malignancies

Free
Nirav N. Shah, Aniko Szabo, Tyce Kearl, Dina Schneider, Walter Longo, Bryon D. Johnson, Peiman Hematti, Mehdi Hamadani, Timothy S. Fenske
Journal: Blood
Blood (2024) 144 (Supplement 1): 3448.
https://doi.org/10.1182/blood-2024-200899
Published: 2024
Journal Articles

Adaptive Manufacturing of LV20.19 CAR T-Cells for Relapsed, Refractory Mantle Cell Lymphoma

Free
Nirav N. Shah, Fateeha Furqan, Aniko Szabo, Tyce Kearl, Anthony Zamora, Jessica Neumann, Parameswaran N. Hari, Dina Schneider, Walter Longo, Peiman Hematti, Bryon D. Johnson, Mehdi Hamadani, Timothy S. Fenske
Journal: Blood
Blood (2023) 142 (Supplement 1): 1024.
https://doi.org/10.1182/blood-2023-173954
Published: 2023
Journal Articles

A Phase 1 Study of CD38-Bispecific Antibody (XmAb18968) for Patients with Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia

Free
Guru Subramanian Guru Murthy, Bijal D. Shah, Adam S Duvall, Jessica T. Leonard, Talha Badar, Cecilia Y. Arana Yi, Tyce Kearl, Arielle Baim, Alexandra M. Harrington, Aniko Szabo, Ehab L. Atallah
Journal: Blood
Blood (2023) 142 (Supplement 1): 4242.
https://doi.org/10.1182/blood-2023-187468
Published: 2023
Journal Articles

A Phase 1 Study of CD38-Bispecific Antibody (XmAb18968) for Patients with CD38 Expressing Relapsed/Refractory Acute Myeloid Leukemia

Free
Guru Subramanian Guru Murthy, Jessica T. Leonard, Talha Badar, Cecilia Y. Arana Yi, Adam S Duvall, Bijal D. Shah, Arielle Baim, Tyce Kearl, Alexandra M. Harrington, Aniko Szabo, Ehab L. Atallah
Journal: Blood
Blood (2023) 142 (Supplement 1): 1541.
https://doi.org/10.1182/blood-2023-187721
Published: 2023
Journal Articles

Dual Targeting of Slamf-7 and CD38 in Mulitple Myeloma (MM): A Phase II Study of Isatuximab, Elotuzumab, Pomalidomide and Dexamethasone (Isa-EloPD) in Relapsed and/or Refractory MM (RRMM)

Free
Binod Dhakal, Meera Mohan, Ravi Narra, Katie Palen, Aniko Szabo, Tyce Kearl, Gayathri Ravi, Susan Bal, Bryon D. Johnson, Marcelo Pasquini, Anita D'Souza, Parameswaran N. Hari, Luciano Costa
Journal: Blood
Blood (2023) 142 (Supplement 1): 3379.
https://doi.org/10.1182/blood-2023-181266
Published: 2023
Journal Articles

Single-Cell RNA Sequencing Identifies Expression Patterns Associated with Clinical Responses to Dual-Targeted CAR-T Cell Therapy

Free
Tyce Kearl, MD PhD, Ao Mei, Ryan Brown, Bryon Johnson, PhD, Dina Schneider, PhD, Boro Dropulic, PhDMBA, Parameswaran Hari, MD MRCP, Nirav N. Shah, MD, Subramaniam Malarkannan, PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 33–34.
https://doi.org/10.1182/blood-2020-142937
Published: 2020