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Siegfried Janz
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Journal Articles

Genome-Wide Association Study Identifies Novel Loci Associated with Survival in Multiple Myeloma

Remy Lee, Shahram Arsang-Jang, Anita D'Souza, Binod Dhakal, Siegfried Janz, Jing Dong
Journal: Blood
Blood (2024) 144 (Supplement 1): 4719.
https://doi.org/10.1182/blood-2024-201795
Published: 2024
Journal Articles

Activation-Inducible Bispecific BCMA-CD24 CAR-T Cells Precisely and Safely Control Multiple Myeloma Growth

Fumou Sun, Jing Dong, Peiman Hematti, Siegfried Janz, Binod Dhakal
Journal: Blood
Blood (2024) 144 (Supplement 1): 4791.
https://doi.org/10.1182/blood-2024-205476
Published: 2024
Journal Articles

Inhibiting FOXM1 Sensitizes Myeloma Cells to BCL2 Inhibitor Venetoclax By Repressing MYC Pathway

Vivian Zhou, Luke Moat, Manya Yu, Deepak Parashar, Abdul Shour, Liang Zhang, Terrie Kitchner, Sanjay Shukla, Song Guo, Gene Ananiev, Benita S. Katzenellenbogen, John Katzenellenbogen, Adedayo Onitilo, Siegfried Janz, Zhi Wen
Journal: Blood
Blood (2023) 142 (Supplement 1): 1950.
https://doi.org/10.1182/blood-2023-180268
Published: 2023
Journal Articles

Transgenic Mouse Model for Translational Immunotherapy Studies on Multiple Myeloma

Manya Yu, Vivian Zhou, Michael D Pisano, Deepak Parashar, Xing Cui, Siegfried Janz
Journal: Blood
Blood (2023) 142 (Supplement 1): 6565.
https://doi.org/10.1182/blood-2023-173410
Published: 2023
Journal Articles

A 12 Gene Signature Accurately Predicts Multiple Myeloma Progression from Monoclonal Gammopathy of Undetermined Significance

Fumou Sun, Jun Ying, Yan Cheng, David Mery, Visanu Wanchai, Eric R. Siegel, Hongwei Xu, Dongzheng Gai, Jiahao Xu, Timothy Cody Ashby, Clyde Bailey, Samer Al Hadidi, Carolina Schinke, Sharmilan Thanendrarajan, Maurizio Zangari, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan
Journal: Blood
Blood (2022) 140 (Supplement 1): 264–265.
https://doi.org/10.1182/blood-2022-163654
Published: 2022
Journal Articles

Chimeric Antigen Receptor-T (CAR-T) Cell Therapy Targeting BCMA in Patients with Prior Allogeneic Transplantation (allo-HCT) in Relapsed and/or Refractory Multiple Myeloma (RRMM)

Lindsay Hammons, Shabi Haider, Marcelo C Pasquini, Saurabh Chhabra, Sabarinath Radhakrishnan, Anthony E. Zamora, Meera Mohan, Jing Dong, Siegfried Janz, Anita D'Souza, Parameswaran Hari, Binod Dhakal
Journal: Blood
Blood (2022) 140 (Supplement 1): 7215–7216.
https://doi.org/10.1182/blood-2022-165483
Published: 2022
Journal Articles

Association of Human Leukocyte Antigen Variants with Progression of Monoclonal Gammopathy of Undetermined Significance to Multiple Myeloma

Ben Massat, Gokul Pareek, Christopher Staffi Buradagunta, Bicky Thapa, Paul Auer, Binod Dhakal, Siegfried Janz, Parameswaran Hari, Jing Dong
Journal: Blood
Blood (2022) 140 (Supplement 1): 10063–10064.
https://doi.org/10.1182/blood-2022-160086
Published: 2022
Journal Articles

Impaired Plasma B Cell Markers in CD138+ Cells Predict Prognosis in Multiple Myeloma

Jing Dong, Jian-Rong Li, Christopher Staffi Buradagunta, Siegfried Janz, Raul Urrutia, Chao Cheng
Journal: Blood
Blood (2022) 140 (Supplement 1): 10054–10055.
https://doi.org/10.1182/blood-2022-158718
Published: 2022
Journal Articles

Clinical Outcome of Patients with Relapsed Refractory Multiple Myeloma Listed for BCMA Directed Commercial CAR T Therapy

Samer Al Hadidi, Aniko Szabo, Jean Esselmann, Lindsay Hammons, Munawwar Hussain, Yetunde Ogunsesan, Nishanth Thalambedu, Fatima Khan, Jaskirat Sethi, Abhishek Janardan, Sabarinath Radhakrishnan, Sharmilan Thanendrarajan, Carolina Schinke, Binod Dhakal, Siegfried Janz, Saurabh Chhabra, Anita D'Souza, Maurizio Zangari, Frits van Rhee, Meera Mohan
Journal: Blood
Blood (2022) 140 (Supplement 1): 8038–8039.
https://doi.org/10.1182/blood-2022-168794
Published: 2022
Journal Articles

Characteristics Associated with Disparities in Survival between Hispanic and Non-Hispanic White Patients with Multiple Myeloma: A Matched Cohort Study

Jing Dong, Zhuping Garacci, Christopher Staffi Buradagunta, Meera Mohan, Anita D'Souza, Ashley Cunningham, Siegfried Janz, Binod Dhakal, Parameswaran Hari
Journal: Blood
Blood (2021) 138 (Supplement 1): 4091.
https://doi.org/10.1182/blood-2021-148880
Published: 2021
Journal Articles

Bispecific CAR-T Cells Targeting Both BCMA and CD24: A Potentially Treatment Approach for Multiple Myeloma

Fumou Sun, Yan Cheng, Bailu Peng, Hongwei Xu, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr., Fenghuang Zhan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2802.
https://doi.org/10.1182/blood-2021-148543
Published: 2021
Journal Articles

NEK2 Inhibition Enhances the Efficacy of PD-1/PD-L1 Blockade in Multiple Myeloma

Yan Cheng, Fumou Sun, Huojun Cao, Dongzheng Gai, Bailu Peng, Hongwei Xu, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr., Fenghuang Zhan
Journal: Blood
Blood (2021) 138 (Supplement 1): 2671.
https://doi.org/10.1182/blood-2021-148659
Published: 2021
Journal Articles

MYC needs MNT to drive B cells over the edge

Siegfried Janz
Journal: Blood
Blood (2020) 135 (13): 977–978.
https://doi.org/10.1182/blood.2019004766
Published: 2020
Journal Articles

Coactivation of NF-κB and Notch signaling is sufficient to induce B-cell transformation and enables B-myeloid conversion

Yan Xiu, Qianze Dong, Lin Fu, Aaron Bossler, Xiaobing Tang, Brendan Boyce, Nicholas Borcherding, Mariah Leidinger, José Luis Sardina, Hai-hui Xue, Qingchang Li, Andrew Feldman, Iannis Aifantis, Francesco Boccalatte, Lili Wang, Meiling Jin, Joseph Khoury, Wei Wang, Shimin Hu, Youzhong Yuan, Endi Wang, Ji Yuan, Siegfried Janz, John Colgan, Hasem Habelhah, Thomas Waldschmidt, Markus Müschen, Adam Bagg, Benjamin Darbro, Chen Zhao
Journal: Blood
Blood (2020) 135 (2): 108–120.
https://doi.org/10.1182/blood.2019001438
Published: 2020
Includes: Supplemental data
Journal Articles

Myeloma sleeper agent in myeloid disguise

Binod Dhakal, Siegfried Janz
Journal: Blood
Blood (2019) 134 (1): 3–4.
https://doi.org/10.1182/blood.2019001273
Published: 2019
Journal Articles

New wrinkle on deubiquitination in B-cell lymphoma

Siegfried Janz
Journal: Blood
Blood (2018) 132 (24): 2529–2530.
https://doi.org/10.1182/blood-2018-10-878611
Published: 2018
Journal Articles

FOXM1, CDK6 and Rb Dependent Drug Resistance and Senescence in Myeloma

Chunyan Gu, PhD, Ruini Chen, PhD, Xuefang Jing, PhD, Siegfried Janz, Ye Yang, PhD
Journal: Blood
Blood (2016) 128 (22): 4456.
https://doi.org/10.1182/blood.V128.22.4456.4456
Published: 2016
Journal Articles

Mouse model of MYD88 L265P -dependent DLBCL

Siegfried Janz
Journal: Blood
Blood (2016) 127 (22): 2660–2661.
https://doi.org/10.1182/blood-2016-04-710434
Published: 2016
Journal Articles

Low Expression of CXCR4 in Bortezomib-Resistant Multiple Myeloma Correlates with Extramedullary Disease in a Murine Mouse Model

Holly A. F. Stessman, Aatif Mansoor, Fenghuang Zhan, MD, PhD, Guido J. Tricot, MD, PhD, John Sunderland, PhD, Susan A. Walsh, Siegfried Janz, M.D., Brian Van Ness, Ph.D., Linda B. Baughn, Ph.D.
Journal: Blood
Blood (2012) 120 (21): 442.
https://doi.org/10.1182/blood.V120.21.442.442
Published: 2012
Journal Articles

HHV-8–encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice

Jan Suthaus, Christiane Stuhlmann-Laeisz, Van S. Tompkins, Timothy R. Rosean, Wolfram Klapper, Giovanna Tosato, Siegfried Janz, Jürgen Scheller, Stefan Rose-John
Journal: Blood
Blood (2012) 119 (22): 5173–5181.
https://doi.org/10.1182/blood-2011-09-377705
Published: 2012
Includes: Supplemental data