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Journal Articles

Identification of Risk Factors for Myeloma Progression in African American Patients

David E. Mery, Yihao Zhan, Hongling Peng, Eric Siegel, Cody Ashby, Clyde Bailey, Catherine Ma, Hongwei Xu, Samer Al Hadidi, Carolina Schinke, Maurizio Zangari, Sharmilan Thanendrarajan, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2024) 144 (Supplement 1): 1937.

https://doi.org/10.1182/blood-2024-212173

Published: 2024

Journal Articles

Of Seven Molecular Subtypes in MGUS the Low Bone Disease (LB) Subtype Exhibits Resistance to Multiple Myeloma Progression

Catherine Ma, Fumou Sun, Clyde Bailey, Hongwei Xu, Samer Al Hadidi, Carolina Schinke, Maurizio Zangari, Sharmilan Thanendrarajan, Frits van Rhee, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2024) 144 (Supplement 1): 4676.

https://doi.org/10.1182/blood-2024-204135

Published: 2024

Journal Articles

The Role of CST6 in Immunosuppression in the Multiple Myeloma Microenvironment

Zijun Zhang, Yan Cheng, David E. Mery, Hongwei Xu, Brian Koss, Behjatolah Monzavi Karbassi, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2024) 144 (Supplement 1): 4661.

https://doi.org/10.1182/blood-2024-204026

Published: 2024

Journal Articles

The Low-Bone (LB) Subtype of Multiple Myeloma Exhibits an Inferior Outcome in African Americans

Yihao Zhan, Hongling Peng, David E. Mery, Eric Siegel, Clyde Bailey, Catherine Ma, Hongwei Xu, Daisy V. Alapat, Samer Al Hadidi, Carolina Schinke, Maurizio Zangari, Sharmilan Thanendrarajan, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2024) 144 (Supplement 1): 1904.

https://doi.org/10.1182/blood-2024-203848

Published: 2024

Journal Articles

Single Nuclei Multiomic Profiling of Transcriptional and Chromatin Accessibility of Tumor Cells Underlines Extensive Cis-Regulatory Interaction during Multiple Myeloma Progression

Visanu Wanchai, Hongwei Xu, Cody Ashby, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2024) 144 (Supplement 1): 1885.

https://doi.org/10.1182/blood-2024-205344

Published: 2024

Journal Articles

Multi-Omics Reveal Immune Microenvironment Alterations in Multiple Myeloma and Its Precursor Stages

Blood (2024) 144 (Supplement 1): 4729.

https://doi.org/10.1182/blood-2024-193583

Published: 2024

Journal Articles

Global Proteomics Identifies CDK11A/B As Integral to Myeloma Proliferation and High-Risk Disease

David E. Mery, Visanu Wanchai, Cody Ashby, Hongwei Xu, Eric Siegel, Clyde Bailey, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2023) 142 (Supplement 1): 1932.

https://doi.org/10.1182/blood-2023-187592

Published: 2023

Journal Articles

Suppression of TRIP13 Induces Metabolic Changes and Potentiates Ferroptosis in Multiple Myeloma

Yan Cheng, Fumou Sun, Wancheng Guo, Hongwei Xu, Prasanth Viswanathan, Mark Manzano, Eric Siegel, Samer Al Hadidi, Carolina Schinke, Maurizio Zangari, Marta Chesi, P. Leif Bergsagel, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2023) 142 (Supplement 1): 3309.

https://doi.org/10.1182/blood-2023-187001

Published: 2023

Journal Articles

The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions

Fumou Sun, Yan Cheng, Jin-Ran Chen, Visanu Wanchai, David E. Mery, Hongwei Xu, Dongzheng Gai, Samer Al Hadidi, Carolina Schinke, Sharmilan Thanendrarajan, Maurizio Zangari, Frits van Rhee, John D Shaughnessy, Jr, Guido Tricot, Fenghuang Zhan

Blood (2023) 142 (Supplement 1): 452.

https://doi.org/10.1182/blood-2023-181853

Published: 2023

Journal Articles

Single Nuclei Multiomics Analysis of Transcriptional and Chromatin Accessibility of Tumor Cells Uncovers Molecular Signatures and Regulatory Elements of Malignant Clonal Evolution in Multiple Myeloma

Visanu Wanchai, Hongwei Xu, Cody Ashby, Frits van Rhee, Guido Tricot, John D Shaughnessy, Jr, Fenghuang Zhan

Blood (2023) 142 (Supplement 1): 87.

https://doi.org/10.1182/blood-2023-181279

Published: 2023

Journal Articles

A 12 Gene Signature Accurately Predicts Multiple Myeloma Progression from Monoclonal Gammopathy of Undetermined Significance

Blood (2022) 140 (Supplement 1): 264–265.

https://doi.org/10.1182/blood-2022-163654

Published: 2022

Journal Articles

Bispecific CAR-T Cells Targeting Both BCMA and CD24: A Potentially Treatment Approach for Multiple Myeloma

Fumou Sun, Yan Cheng, Bailu Peng, Hongwei Xu, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr., Fenghuang Zhan

Blood (2021) 138 (Supplement 1): 2802.

https://doi.org/10.1182/blood-2021-148543

Published: 2021

Journal Articles

NEK2 Inhibition Enhances the Efficacy of PD-1/PD-L1 Blockade in Multiple Myeloma

Yan Cheng, Fumou Sun, Huojun Cao, Dongzheng Gai, Bailu Peng, Hongwei Xu, Frits van Rhee, Siegfried Janz, Guido Tricot, John D Shaughnessy, Jr., Fenghuang Zhan

Blood (2021) 138 (Supplement 1): 2671.

https://doi.org/10.1182/blood-2021-148659

Published: 2021

Journal Articles

The Interaction of NEK2 with USP7 Causes Resistance to Proteasome Inhibitor in Multiple Myeloma

Reinaldo Franqui-Machin, Mu Hao, PhD, Bai Hua, Zhimin Gu, PhD, Xin Zhan, Hongwei Xu, Hasem Habelhah, Yogesh Jethava, MBBS,MDFRCPath,MRCP, Lugui Qiu, MD, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2017) 130 (Supplement 1): 593.

https://doi.org/10.1182/blood.V130.Suppl_1.593.593

Published: 2017

Journal Articles

Multiple Myeloma Tumor Cells Are Selectively Killed By Pharmacologically-Dosed Ascorbic Acid

Reinaldo Franqui-Machin, Hongwei Xu, Yogesh Yethava, Ivana Frech, DSc, PhD MBA, Guido J. Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2017) 130 (Supplement 1): 5391.

https://doi.org/10.1182/blood.V130.Suppl_1.5391.5391

Published: 2017

Journal Articles

Nek2 Stabilization By Usp7 Leads to Activation of NF-Kb in Multiple Myeloma

Reinaldo Franqui Machin, BS, Xin Zhan, BA, Hongwei Xu, DDS, Ivana Frech, DSc, PhD MBA, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2016) 128 (22): 4418.

https://doi.org/10.1182/blood.V128.22.4418.4418

Published: 2016

Journal Articles

Drug Resistant Myeloma Cells Cause More Severe Bone Destruction in Myeloma

Mu Hao, MD PhD, Zhimin Gu, PhD, Reinaldo Franqui Machin, Hongwei Xu, Gregory S. Thomas, PhD, Lugui Qiu, MD PhD, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2015) 126 (23): 839.

https://doi.org/10.1182/blood.V126.23.839.839

Published: 2015

Journal Articles

Targeting Neddylation to Overcome Drug Resistance in Multiple Myeloma

Gregory S Thomas, PhD, Junwei Huang, MD, Yi Zhou, PhD, Zhimin Gu, PhD, Ye Yang, PhD, Hongwei Xu, Guido J Tricot, MD PhD, Fenghuang Zhan, MD PhD

Blood (2015) 126 (23): 1804.

https://doi.org/10.1182/blood.V126.23.1804.1804

Published: 2015

Journal Articles

Decreased FPN1 in Myeloma Promotes Malignant Cell Growth and Osteoclast Differentiation

Zhimin Gu, PhD, He Wang, PhD, Jiliang Xia, MS, Ivana De Domenico, PhD, Ye Yang, PhD, Junwei Huang, MD, Hongwei Xu, DDS, Zhengdong Jin, PhD, Guido J. Tricot, MD, PhD, Fenghuang Zhan, MD PhD

Blood (2014) 124 (21): 2017.

https://doi.org/10.1182/blood.V124.21.2017.2017

Published: 2014

Journal Articles

NEK2 Suppresses Cellular Senescence through Regulation of the β-Catenin/CCND2/RB Axis in Multiple Myeloma

Ye Yang, PhD, Guido J. Tricot, MD, PhD, Xia Jiliang, Zhimin Gu, PhD, Hongwei Xu, DDS, Mu Hao, PhD, Fenghuang Zhan, MD PhD

Blood (2014) 124 (21): 2024.

https://doi.org/10.1182/blood.V124.21.2024.2024

Published: 2014

NARROW

Identification of Risk Factors for Myeloma Progression in African American Patients

Of Seven Molecular Subtypes in MGUS the Low Bone Disease (LB) Subtype Exhibits Resistance to Multiple Myeloma Progression

The Role of CST6 in Immunosuppression in the Multiple Myeloma Microenvironment

The Low-Bone (LB) Subtype of Multiple Myeloma Exhibits an Inferior Outcome in African Americans

Single Nuclei Multiomic Profiling of Transcriptional and Chromatin Accessibility of Tumor Cells Underlines Extensive Cis-Regulatory Interaction during Multiple Myeloma Progression

Multi-Omics Reveal Immune Microenvironment Alterations in Multiple Myeloma and Its Precursor Stages

Global Proteomics Identifies CDK11A/B As Integral to Myeloma Proliferation and High-Risk Disease

Suppression of TRIP13 Induces Metabolic Changes and Potentiates Ferroptosis in Multiple Myeloma

The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions

Single Nuclei Multiomics Analysis of Transcriptional and Chromatin Accessibility of Tumor Cells Uncovers Molecular Signatures and Regulatory Elements of Malignant Clonal Evolution in Multiple Myeloma

A 12 Gene Signature Accurately Predicts Multiple Myeloma Progression from Monoclonal Gammopathy of Undetermined Significance

Bispecific CAR-T Cells Targeting Both BCMA and CD24: A Potentially Treatment Approach for Multiple Myeloma

NEK2 Inhibition Enhances the Efficacy of PD-1/PD-L1 Blockade in Multiple Myeloma

The Interaction of NEK2 with USP7 Causes Resistance to Proteasome Inhibitor in Multiple Myeloma

Multiple Myeloma Tumor Cells Are Selectively Killed By Pharmacologically-Dosed Ascorbic Acid

Nek2 Stabilization By Usp7 Leads to Activation of NF-Kb in Multiple Myeloma

Drug Resistant Myeloma Cells Cause More Severe Bone Destruction in Myeloma

Targeting Neddylation to Overcome Drug Resistance in Multiple Myeloma

Decreased FPN1 in Myeloma Promotes Malignant Cell Growth and Osteoclast Differentiation

NEK2 Suppresses Cellular Senescence through Regulation of the β-Catenin/CCND2/RB Axis in Multiple Myeloma

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American Society of Hematology

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ASH Publications

American Society of Hematology

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