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Journal Articles

Escalating Doses of AZD0486, a Novel CD19xCD3 T-Cell Engager, Result in High Complete Remissions with Rapid Clearance of Minimal Residual Disease in Patients with Relapsed/Refractory Follicular Lymphoma

Jing-Zhou Hou, Ranjit Nair, Ryan Jacobs, Tae Min Kim, Seok-Goo Cho, Dai Maruyama, Sumana Devata, Yazeed Sawalha, Dok Hyun Yoon, Constantine S. Tam, Koji Izutsu, Matthew Matasar, Don A. Stevens, Aravind Ramakrishnan, Denise Brennan, Xu Zhu, Robin Lesley, Yasuhiro Oki, David Sermer, Sameh Gaballa
Journal: Blood
Blood (2024) 144 (Supplement 1): 341.
https://doi.org/10.1182/blood-2024-193589
Published: 2024
Journal Articles

A Phase 1 Study of P-BCMA-ALLO1, a Non-Viral, Allogeneic BCMA Directed CAR-T in Relapsed/Refractory Multiple Myeloma (RRMM): Results from Optimized Lymphodepletion Cohort

Bhagirathbhai Dholaria, Leyla O. Shune, Mehmet H. Kocoglu, Andrew Kin, Aravind Ramakrishnan, Ehsan Malek, Siddhartha Ganguly, Christopher Strouse, Jose Carlos Cruz, Edward Anthony Faber, Katherine McArthur, Jeff D Eskew, Joanne McCaigue, Samuel DePrimo, Chris E Martin, Sabrina Haag, Hamid Namini, Ellen Christie, Rajesh Belani, Syed Rizvi, Stacey A Cranert, Julia Coronella, Devon J Shedlock, Caitlin Costello
Journal: Blood
Blood (2024) 144 (Supplement 1): 4828.
https://doi.org/10.1182/blood-2024-207459
Published: 2024
Journal Articles

MagnetisMM-9: Efficacy and Safety of Step-up Priming Doses and Longer Dosing Intervals of Elranatamab (ELRA) in Patients with Relapsed or Refractory Multiple Myeloma (RRMM)

Matthew Pianko, Charlotte Pawlyn, Shang-Yi Huang, Tadao Ishida, Douglas W Sborov, Shinsuke Iida, Aravind Ramakrishnan, Reuben Benjamin, Rakesh Popat, Steven Schuster, Junya Kuroda, Chia-Jen Liu, Anne Philippe, Umberto Conte, Fangxin Hong, Erik Vandendries, Rafael Fonseca
Journal: Blood
Blood (2024) 144 (Supplement 1): 4743.
https://doi.org/10.1182/blood-2024-205872
Published: 2024
Journal Articles

Rapcabtagene Autoleucel (YTB323) in Patients (Pts) with Relapsed/Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL): Phase II Trial Clinical Update

Peter A. Riedell, Mi Kwon, Ian W. Flinn, Michael J. Dickinson, Carlos Solano, Ulrich Jaeger, Javier Briones, Koji Kato, Shaun Fleming, Emmanuel Bachy, Alessandro Rambaldi, Leyla O. Shune, Nirav N. Shah, Didier Blaise, Matthew J. Frigault, Aravind Ramakrishnan, Anne Yang, David Pearson, Aiesha Zia, Eduardo Segura, Aisha Masood, Pere Barba
Journal: Blood
Blood (2024) 144 (Supplement 1): 67.
https://doi.org/10.1182/blood-2024-204264
Published: 2024
Journal Articles

Evaluation of AZD0486, a Novel CD19xCD3 T-Cell Engager, in Relapsed/Refractory Diffuse Large B-Cell Lymphoma in an Ongoing First-in-Human Phase 1 Study: High Complete Responses Seen in CAR-T-Naive and CAR-T-Exposed Patients

Sameh Gaballa, Jing-Zhou Hou, Sumana Devata, Seok-Goo Cho, Ranjit Nair, Dok Hyun Yoon, Ryan Jacobs, Koji Izutsu, Don A. Stevens, Dai Maruyama, Constantine S. Tam, Yazeed Sawalha, Aravind Ramakrishnan, Matthew Matasar, Denise Brennan, Sue Zhu, Robin Lesley, Yasuhiro Oki, David Sermer, Tae Min Kim
Journal: Blood
Blood (2024) 144 (Supplement 1): 868.
https://doi.org/10.1182/blood-2024-193681
Published: 2024
Journal Articles

Comparison of 15- Vs. 30-Day Remote Patient Monitoring for Outpatient Chimeric Antigen Receptor T-Cell Therapy (CAR-T) across a Large Health System

Tonya Cox, Nicole Zahradka, Casey Martin, Betsy Blunk, Rocky L. Billups, Sarah Meissner, Hannah Sowell, Stephanie Larson, Meredith Perez, Aravind Ramakrishnan, Paul Shaughnessy, Ashleigh Smith, Michael T. Tees, Jeremy Pantin, Benjamin Zaniello, Navneet Majhail, Minoo Battiwalla
Journal: Blood
Blood (2024) 144 (Supplement 1): 2300.
https://doi.org/10.1182/blood-2024-211566
Published: 2024
Journal Articles

Bendamustine Versus Fludarabine and Cyclophosphamide for Lymphodepletion Prior to CAR-T Therapy

Uttam K Rao, Betsy Blunk, Carlos Bachier, Vikas Bhushan, Jose Carlos Cruz, Mohammed Elayan, Ian W. Flinn, Tara Gregory, Charles F. LeMaistre, Navneet Majhail, Shahbaz A. Malik, Casey Martin, Michael B. Maris, John Mathews, Luke Mountjoy, Jeremy M. Pantin, Aravind Ramakrishnan, Paul Shaughnessy, Michael T. Tees, Estil A. Vance, Behyar Zoghi, MD, PhD, FACP, Minoo Battiwalla
Journal: Blood
Blood (2023) 142 (Supplement 1): 3504.
https://doi.org/10.1182/blood-2023-190388
Published: 2023
Journal Articles

Standardization of Outpatient Care after CAR-T Therapy across a Large Cell Therapy Network- through Technology and Decentralized Virtual Nurses: Preliminary Results

Tonya Cox, Nicole Zahradka, Rocky L. Billups, Betsy Blunk, Rebecca Campo, Trista Carelock, Mary Husband, Charles F. LeMaistre, Navneet Majhail, Casey Martin, Sarah Meissner, Jeremy Pantin, Meredith Perez, Juliana Pugmire, Aravind Ramakrishnan, Paul Shaughnessy, Ashleigh Smith, Michael T. Tees, Matt Wilkes, Megan Yates, Minoo Battiwalla
Journal: Blood
Blood (2023) 142 (Supplement 1): 254.
https://doi.org/10.1182/blood-2023-187253
Published: 2023
Journal Articles

Preliminary Results of Nathali-01: A First-in-Human Phase I/IIa Study of UCART20x22, a Dual Allogeneic CAR-T Cell Product Targeting CD20 and CD22, in Relapsed or Refractory (R/R) Non-Hodgkin Lymphoma (NHL)

Jeremy S. Abramson, Aravind Ramakrishnan, Ana Alfonso Pierola, Ira Braunschweig, Guillaume Cartron, Catherine Thieblemont, Jose A. Pérez-Simón, Pere Barba, Peter A. Riedell, Carlos Solano, Thomas Gastinne, Alexandra LaCroce, Denise Thomas, Camille Poirot, Sarah Meadows, Kathryn J. Newhall, Daniel J. Lee, Mark G. Frattini, Emmanuel Bachy
Journal: Blood
Blood (2023) 142 (Supplement 1): 2110.
https://doi.org/10.1182/blood-2023-186570
Published: 2023
Journal Articles

Early Safety Results of P-BCMA-ALLO1, a Fully Allogeneic Chimeric Antigen Receptor T-Cell (CAR-T), in Patients with Relapsed / Refractory Multiple Myeloma (RRMM)

Bhagirathbhai Dholaria, Mehmet H. Kocoglu, Andrew Kin, Adam S. Asch, Aravind Ramakrishnan, Carlos Bachier, Tulio E. Rodriguez, Leyla Shune, Katherine McArthur, Joanne McCaigue, Samuel DePrimo, Chris Martin, Sabrina Haag, Maggie Zhang, Hamid Namini, Ellen Christie, Rajesh Belani, Stacey A Cranert, Julia Coronella, Devon J Shedlock, Caitlin L. Costello
Journal: Blood
Blood (2023) 142 (Supplement 1): 3479.
https://doi.org/10.1182/blood-2023-182430
Published: 2023
Journal Articles

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma

Clinical Trials & Observations
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G. R. Peddareddigari, Nushmia Khokhar, Robert Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve A. O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin A. Pule
Journal: Blood
Blood (2023) 141 (20): 2470–2482.
https://doi.org/10.1182/blood.2022018598
Published: 2023
Includes: Supplemental data
Journal Articles

Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar Study

Clinical Trials & Observations
Corey Cutler, Stephanie J. Lee, Sally Arai, Marcello Rotta, Behyar Zoghi, Aleksandr Lazaryan, Aravind Ramakrishnan, Zachariah DeFilipp, Amandeep Salhotra, Wanxing Chai-Ho, Rohtesh Mehta, Trent Wang, Mukta Arora, Iskra Pusic, Ayman Saad, Nirav N. Shah, Sunil Abhyankar, Carlos Bachier, John Galvin, Annie Im, Amelia Langston, Jane Liesveld, Mark Juckett, Aaron Logan, Levanto Schachter, Asif Alavi, Dianna Howard, Harlan W. Waksal, John Ryan, David Eiznhamer, Sanjay K. Aggarwal, Jonathan Ieyoub, Olivier Schueller, Laurie Green, Zhongming Yang, Heidi Krenz, Madan Jagasia, Bruce R. Blazar, Steven Pavletic
Journal: Blood
Blood (2021) 138 (22): 2278–2289.
https://doi.org/10.1182/blood.2021012021
Published: 2021
Includes: Supplemental data
Journal Articles

A Phase II Single Arm Study of Nivolumab As Maintenance Therapy after Autologous Stem Cell Transplantation in Patients with Hodgkin Lymphoma at Risk of Relapse or Progression

Carlos Bachier, Henning Schade, Behyar Zoghi, Aravind Ramakrishnan, Nirav N. Shah
Journal: Blood
Blood (2021) 138 (Supplement 1): 2455.
https://doi.org/10.1182/blood-2021-148139
Published: 2021
Journal Articles

Reduction in Transplantation Activity without Impairment in Outcomes in the Covid-19 Era- Data from the Sarah Cannon Blood Cancer Network (SCBCN)

Minoo Battiwalla, MD, Carlos Bachier, MD, Vikas Bhushan, MD, Michael J. Eckrich, MD MPH, Alireza Eghtedar, MD, Haydar Frangoul, MD, Suman Kambhampati, MD, Shahbaz Malik, MD, Peter A. McSweeney, MD, Jeremy Pantin, MBBS, Aravind Ramakrishnan, MD, Hana Safah, MD, Paul J Shaughnessy, MD, Betsy Blunk, BSN, RN, BMTCN, Tonya Cox, BSN, RN, Rocky Billups, MS, Charles F. Lemaistre, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 26–27.
https://doi.org/10.1182/blood-2020-139121
Published: 2020
Journal Articles

Belumosudil for Chronic Graft-Versus-Host Disease (cGVHD) after 2 or More Prior Lines of Therapy: The Rockstar Study (KD025-213)

Corey Cutler, MD MPH, FRCPC, Stephanie J. Lee, MDMPH, Sally Arai, MD MS, Marcello Rotta, MD, Behyar Zoghi, MD, Aravind Ramakrishnan, MD, David Eiznhamer, PhD, Olivier Schueller, PhD, Zhongming Yang, PhD, Laurie S. Green, MD, Sanjay K. Aggarwal, MD, Bruce R. Blazar, MD, Steven Z. Pavletic, MD MS, Madan Jagasia, MBBS, MS, MMHC
Journal: Blood
Blood (2020) 136 (Supplement 1): 45–46.
https://doi.org/10.1182/blood-2020-139445
Published: 2020
Journal Articles

Monocyte and Fibroblast Directed Generation of a Marrow Vascular Niche

Surya S Kotha, Kiet T Phong, Amie Adams, Brian Hayes, PhD, Meredith A Roberts, Karol Bomsztyk, MD, Aravind Ramakrishnan, MD, Beverly Torok-Storb, PhD, Ying Zheng, PhD
Journal: Blood
Blood (2015) 126 (23): 3602.
https://doi.org/10.1182/blood.V126.23.3602.3602
Published: 2015
Journal Articles

SRSF2 Mutations Impair Hematopoietic Differentiation By Altering Exonic Splicing Enhancer Preference

Eunhee Kim, PhD, Janine O. Ilagan, PhD, Stanley Lee, PhD, Aravind Ramakrishnan, MD, Young Rock Chung, MS, Jean-Baptiste Micol, MD, Michele E. Murphy, Min-Kyung Kim, BS, Ahmad S. Zebari, Jacob Feala, Silvia Buonamici, PhD, Peter G Smith, PhD, H. Joachim Deeg, MD, Camille Lobry, PhD, Iannis Aifantis, PhD MSC, Robert K. Bradley, PhD, Omar Abdel-Wahab, MD
Journal: Blood
Blood (2014) 124 (21): 824.
https://doi.org/10.1182/blood.V124.21.824.824
Published: 2014
Journal Articles

U2AF1 Mutations Cause Allele-Specific Alterations in 3' Splice Site Recognition in Myeloid Malignancies

Janine O. Ilagan, PhD, Aravind Ramakrishnan, MD, Brian Hayes, PhD, Michele E. Murphy, Ahmad S. Zebari, Philip Bradley, PhD, Robert K. Bradley, PhD
Journal: Blood
Blood (2014) 124 (21): 1889.
https://doi.org/10.1182/blood.V124.21.1889.1889
Published: 2014
Journal Articles

Five-group cytogenetic risk classification, monosomal karyotype, and outcome after hematopoietic cell transplantation for MDS or acute leukemia evolving from MDS

Clinical Trials & Observations
H. Joachim Deeg, Bart L. Scott, Min Fang, Howard M. Shulman, Boglarka Gyurkocza, David Myerson, John M. Pagel, Uwe Platzbecker, Aravind Ramakrishnan, Jerald P. Radich, Brenda M. Sandmaier, Mohamed Sorror, Derek L. Stirewalt, Wendy A. Wilson, Rainer Storb, Frederick R. Appelbaum, Ted Gooley
Journal: Blood
Blood (2012) 120 (7): 1398–1408.
https://doi.org/10.1182/blood-2012-04-423046
Published: 2012
Includes: Supplemental data
Journal Articles

Derivation, Characterization, and In Vitro Differentiation of Canine Embryonic Stem Cells.

Aravind Ramakrishnan, Brian Hayes, Sara R. Fagerlie, Szczepan Baran, Michael Harkey, Lynn Graf, Merav Bar, Ausra Bendoraite, Muneesh Tewari, Beverly Torok-Storb
Journal: Blood
Blood (2007) 110 (11): 4059.
https://doi.org/10.1182/blood.V110.11.4059.4059
Published: 2007