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Wendy Osborne
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Journal Articles

Prognostication and Treatment-Related Outcomes in Secondary Central Nervous System Involvement of Large B-Cell Lymphoma (SCNSL): Evidence from a Large International Cohort

Juan Pablo Alderuccio, Jahanzaib Khwaja, Sunwoo Han, Paola Ghione, Imran A. Nizamuddin, Aditi Saha, Ning Dong, Yucai Wang, Hua-Jay J Cherng, Seda S. Tolu, Nina Wagner-Johnston, Adam J. Olszewski, Natalie Grover, Jean L. Koff, Amrita Desai, Praveen Ramakrishnan Geethakumari, Tamara K Moyo, Jose Sandoval-Sus, Narendranath Epperla, Danielle S Wallace, Manali Kamdar, Alexey Danilov, Han W. Tun, Javier Munoz, Mayur S. Narkhede, Joanna M. Rhodes, Anca Prica, Andrea Kuhnl, Adrian Maraj, Jessica Okosun, Jeffery Smith, Wendy Osborne, Victoria Calvert, Dima el-Sharkawi, Ammar Hilali, Graham P. Collins, Kim Linton, Nagah Elmusharaf, Anna Santarsieri, Farheen Karim, Thomas Ollila, Sarah Monick, Iris Margalit Trutzer, Nilanjan Ghosh, Jones Can, Amy Ayers, Jacopo Calabrese De Feo, John Sharp, Rachel Treitman, Avyakta Kallam, Izel Okcu, Vismay Deshani, Firas Baidoun, Chathuri Abeyakoon, William Hann, Aisling Barrett, Brad Kahl, Julio C. Chavez, Kate Cwynarski
Journal: Blood
Blood (2024) 144 (Supplement 1): 571.
https://doi.org/10.1182/blood-2024-199781
Published: 2024
Journal Articles

Glofitamab and Epcoritamab in the Real World: A UK Multicentre Retrospective Analysis of Efficacy, Tolerability and Practical Implications

Euan Haynes, Kushani Ediriwickrema, Sarah Lawless, Kevin Joyce, Matthew Wells, Jeffrey Smith, Kim Linton, Anna Santarsieri, George Follows, John Willan, Robert Osborn, Matthew R Wilson, Pamela McKay, Mahina Baloch, Rory McCulloch, Mary Gleeson, David Wrench, David Foldes, Edward Kanfer, Kyaw Zin Maw, Andrea Kuhnl, Matthew Ahearne, Mary Owen, Jane Norman, Ravindu De Silva, Nimish Shah, Harriet Ambrose, Christopher P. Fox, Janine Qasim, Graham P. Collins, Martha Vickers, David Tucker, Li Yuan Chan, Sunil Iyengar, Dima el-Sharkawi, Rebecca Auer, Catherine Cox, Hwai Jing Hiew, Andrew J. Davies, Philippa Kelsey, David John Lewis, Abigail Martin, Gavin Preston, Dominic J. Culligan, Angus Broom, William Wilson, Wendy Osborne, William Townsend
Journal: Blood
Blood (2024) 144 (Supplement 1): 3100.
https://doi.org/10.1182/blood-2024-203781
Published: 2024
Journal Articles

Delays to Diagnosis of Peripheral T-Cell Lymphoma and Clinical Utility of Molecular Profiling: A UK Multicentre Real-World Study

Jesca Boot, Elizabeth Nelmes, Findlay Bewicke-Copley, Krushika Paleja, Emily Davenport, Ross Henderson, William Hann, Xiao-Yin Zhang, Hannah Bielby, Harshita Goradia, Naim Rahimi, Amjad Hmaid, Rumman Fatima Nizam, Imogen Welding, Vivek Radhakrishnan, Callum Harris, Danielle Monteil, Andrew Clear, Maria Calaminici, Paul Greaves, Andrew J. Davies, Graham P. Collins, Matthew R Wilson, Jeffery Smith, Christopher P Fox, Wendy Osborne, Lucy Cook, Matthew Ahearne, Kate Cwynarski, John G. Gribben, Jessica Okosun
Journal: Blood
Blood (2024) 144 (Supplement 1): 4445.
https://doi.org/10.1182/blood-2024-205820
Published: 2024
Journal Articles

Multi-Centre Real-World Outcomes of Large B-Cell Lymphoma Patients Treated with 2L Axicabtagene Ciloleucel in the UK

Andrea Kuhnl, Amy A Kirkwood, Claire Roddie, Caroline Besley, Jane Norman, Ben Uttenthal, Frances Seymour, Andrew J. Davies, Wendy Osborne, William Townsend, Emil Arjun Kumar, Amrith Mathew, Carlos Gonzalez Arias, Ceri Jones, Aikaterini Panopoulou, Ahmed Abdulgawad, Edward Bataillard, Pierre McCarthy, Nicolas Martinez-Calle, Vaishali Dulobdas, Rajesh Alajangi, Ram Malladi, Muddeha Waraich, Olateni Awofisayo, Hwai Jing Hiew, Callum Harris, Michael Northend, Adrian Maraj, Shankaranarayana Paneesha, Kasys Meira-Gervatauskas, Kate Cwynarski, Graham P. Collins, Roderick J. Johnson, Robin Sanderson, Maeve O'Reilly, Tobias Menne, Sridhar Chaganti
Journal: Blood
Blood (2024) 144 (Supplement 1): 2342.
https://doi.org/10.1182/blood-2024-200738
Published: 2024
Journal Articles

The influence of immunodeficiency, disease features, and patient characteristics on survival in plasmablastic lymphoma

Clinical Trials & Observations
Pietro R. Di Ciaccio, Mark N. Polizzotto, Kate Cwynarski, Alina S. Gerrie, Catherine Burton, Mark Bower, John Kuruvilla, Silvia Montoto, Pam McKay, Christopher P. Fox, Samuel Milliken, Awachana Jiamsakul, Wendy Osborne, Graham P. Collins, Kate Manos, Kim M. Linton, Sunil Iyengar, Shireen Kassam, Michelle Poon Limei, David Kliman, Nicole Wong Doo, Anne-Marie Watson, Pasquale Fedele, Costas K. Yannakou, Stewart Hunt, Matthew Ku, Laurie H. Sehn, Alexandra Smith, Hanna Renshaw, Alice Maxwell, Qin Liu, Rageshri Dhairyawan, Graeme Ferguson, Keir Pickard, Daniel Painter, Nisha Thakrar, Kevin W. Song, Nada Hamad
Journal: Blood
Blood (2024) 143 (2): 152–165.
https://doi.org/10.1182/blood.2023021348
Published: 2024
Includes: Supplemental data
Journal Articles

Bendamustine Plus Brentuximab Has Superior Efficacy to Brentuximab Monotherapy As Third-Line Treatment for Classical Hodgkin Lymphoma: A Real-World, Multicentre UK Analysis

Rohan Shotton, Amy A Kirkwood, Michael Northend, Dina Fathoala, Kieran Burton, Graeme Ferguson, Laura Aiken, Caroline Shrubsole, Lauren Henry, Mary Owen, Rebecca Oliver, Nicolas Martinez-Calle, Astrid Etherington, Eve Gallop-Evans, Cathy Burton, Fiona Miall, Wendy Osborne, Rifca Le Dieu, Pamela McKay, Satyen H Gohil, Graham P. Collins, Elizabeth H Phillips
Journal: Blood
Blood (2023) 142 (Supplement 1): 6173.
https://doi.org/10.1182/blood-2023-186601
Published: 2023
Journal Articles

Preliminary Findings of a Phase Ib/II Trial Indicate Manageable Safety and Promising Efficacy for Mosunetuzumab in Combination with Lenalidomide (M+Len) in Previously Untreated (1L) Follicular Lymphoma (FL)

Franck Morschhauser, Krish Patel, Sabela Bobillo, Raul Cordoba, Toby A. Eyre, Mark Bishton, Roch Houot, Hui-Lai Zhang, Liqun Zou, Wendy Osborne, Laura Gálvez-Carvajal, Catherine Thieblemont, Donald Yee, Andrea Knapp, Enkhtsetseg Purev, Haocheng Li, Vivian Chen, Karl L. Banta, Jason Sit, Emmanuel Bachy
Journal: Blood
Blood (2023) 142 (Supplement 1): 605.
https://doi.org/10.1182/blood-2023-174432
Published: 2023
Journal Articles

Dual targeting of CD19 and CD22 with bicistronic CAR-T cells in patients with relapsed/refractory large B-cell lymphoma

Clinical Trials & Observations
Claire Roddie, Lazaros J. Lekakis, Maria A. V. Marzolini, Aravind Ramakrishnan, Yiyun Zhang, Yanqing Hu, Vijay G. R. Peddareddigari, Nushmia Khokhar, Robert Chen, Silvia Basilico, Meera Raymond, Frederick Arce Vargas, Kevin Duffy, Wolfram Brugger, Maeve A. O’Reilly, Leigh Wood, David C. Linch, Karl S. Peggs, Carlos Bachier, Elizabeth Lihua Budde, Connie Lee Batlevi, Nancy Bartlett, David Irvine, Eleni Tholouli, Wendy Osborne, Kirit M. Ardeshna, Martin A. Pule
Journal: Blood
Blood (2023) 141 (20): 2470–2482.
https://doi.org/10.1182/blood.2022018598
Published: 2023
Includes: Supplemental data
Journal Articles

Replacing Procarbazine with Dacarbazine in Escalated Beacopp Dramatically Reduces the Post Treatment Haematopoietic Stem and Progenitor Cell Mutational Burden in Hodgkin Lymphoma Patients with No Apparent Loss of Clinical Efficacy

Anna Santarsieri, Emily Mitchell, Katherine Sturgess, Pauline Brice, Tobias F. Menne, Wendy Osborne, Thomas Creasey, Kirit M. Ardeshna, Sarah Behan, Kaljit Bhuller, Stephen Booth, Nikesh D. Chavda, Graham P. Collins, Dominic J. Culligan, Kate Cwynarski, Andrew Davies, Abigail Downing, David Dutton, Michelle Furtado, Eve Gallop-Evans, Andrew Hodson, David Hopkins, Hannah Hsu, Sunil Iyengar, Stephen G. Jones, Kim M. Linton, Oliver C. Lomas, Nicolas Martinez-Calle, Abhinav Mathur, Pamela McKay, Sateesh K. Nagumantry, Deirdre O'Mahony, Elizabeth H. Phillips, Neil Phillips, John F. Rudge, Nimish K. Shah, Gwyneth Stafford, Alex Sternberg, Rachel Trickey, Benjamin J. Uttenthal, Natasha Wetherall, Andrew K. McMillan, Michael Stratton, Elisa Laurenti, Peter J. Campbell, George A. Follows
Journal: Blood
Blood (2022) 140 (Supplement 1): 1761–1764.
https://doi.org/10.1182/blood-2022-166543
Published: 2022
Journal Articles

CD8 Presence and Dynamics in Glofitamab-Treated Patients with Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma Using the CD8-Specific PET Tracer 89 Zr-Crefmirlimab Berdoxam

Martin Hutchings, Annika Loft, Wendy Osborne, George Petrides, Fritz Offner, Ciel De Vriendt, Giuseppe Gritti, Roberto Boni, William Townsend, Irfan Kayani, Ian Wilson, Yanjie Wang, Maria Jadhav, Cristina Santini, Claire Kelly, Martin Kornacker, Jean J.L. Tessier, Ann-Marie E Bröske, Angelika Lahr, Axel Boehnke, Christoph M. Griessinger
Journal: Blood
Blood (2022) 140 (Supplement 1): 10733–10735.
https://doi.org/10.1182/blood-2022-158154
Published: 2022
Journal Articles

Real World Escalated Beacopdac Delivers Similar Outcomes to Escalated Beacopp and Superior Outcomes to Response-Adapted (RATHL) ABVD, While Potentially Reducing Toxicity Compared with Escalated Beacopp

Anna Santarsieri, Katherine Sturgess, Pauline Brice, Tobias F Menne, Wendy Osborne, Thomas Creasey, Kirit M. Ardeshna, Sarah Behan, Kaljit Bhuller, Stephen Booth, Graham P. Collins, Kate Cwynarski, Andrew Davies, Michelle Furtado, Eve Gallop-Evans, Andrew Hodson, Sunil Iyengar, Stephen G Jones, Kim Linton, Nicolas Martinez-Calle, Pamela McKay, Sateesh K Nagumantry, Deirdre O'Mahony, Beth Phillips, Neil Phillips, John F Rudge, Nimish Shah, Gwyneth Stafford, Alex Sternberg, Rachel Trickey, Benjamin J Uttenthal, Nathasha Wetherall, Andrew K McMillan, George A Follows
Journal: Blood
Blood (2021) 138 (Supplement 1): 877.
https://doi.org/10.1182/blood-2021-146242
Published: 2021
Journal Articles

Clinical and Biological Effects of Combined CD27 and CD20 Antibody Therapy in Relapsed/Refractory B-Cell Lymphoma: The Riva Trial

Sean H Lim, Heng Sheng Sow, Christopher Wignall, Katy Mercer, Josh Caddy, Cherish Boxall, Kerensa Thorne, Joshua Northey, Louise Stanton, Zoë Konn, Keira Fines, Patrick G. Medd, Adam Coleman, Lorna Nunn, Robert Lown, Pamela McKay, Wendy Osborne, Kim Linton, Graham P. Collins, Andrew J Gentles, Matthew Rose-Zerilli, Gareth Griffiths
Journal: Blood
Blood (2021) 138 (Supplement 1): 715.
https://doi.org/10.1182/blood-2021-148332
Published: 2021
Journal Articles

Survival Outcomes for Plasmablastic Lymphoma: An International, Multicentre Study By the Australasian Lymphoma Alliance

Pietro R Di Ciaccio, BA/LLB MBBS FRACP FRCPA, Mark N. Polizzotto, MBBS, PhD, Kate Cwynarski, MD PhD, Cathy Burton, MBBChir, MA, MD FRCPath, Awachana Jiamsakul, Mark Bower, MD, John Kuruvilla, MD, Silvia Montoto, MD, Pam McKay, MD, Wendy Osborne, MD, Sam Milliken, MBBS, FRACP, FRCPA, Kim Linton, MBChB, MRCP, PhD, Kate Manos, MBBS, Shireen Kassam, MBBS, FRCPath, PhD, Nicole Wong Doo, MBBS,MDFRACP,FRCPA, Anne-Marie Watson, FRACP, FRCPA, MBBS, Pasquale L Fedele, MBBS PhDFRACP FRCPA, Costas K. Yannakou, MBBS (Hons), FRACP, FRCPA, Stewart Hunt, MBBS, Hanna Renshaw, MD BA, Nisha Thakrar, Alexandra Smith, PhD, Daniel Painter, Alice Maxwell, Qin Liu, MBBS, Rageshri Dhairyawan, Graeme Ferguson, Keir Pickard, Nada Hamad, MBBS,BSc,MSc,FRACP FRCPA
Journal: Blood
Blood (2020) 136 (Supplement 1): 1–2.
https://doi.org/10.1182/blood-2020-134972
Published: 2020
Journal Articles

Sequential Matrix-RICE Therapy Followed By Autologous Stem Cell Transplant in Patients with Diffuse Large B-Cell Lymphoma and Secondary Central Nervous System Involvement: The International Extranodal Lymphoma Study Group-42 Phase II (MARIETTA) Trial

Andres JM Ferreri, MD, Jeanette K. Doorduijn, MD PhD, Chiara Cattaneo, MD, Maria Giuseppina Cabras, MD, Jeffery Smith, MBChB BMedSci MRCP FRCPath, Fiorella Ilariucci, Franco Narni, Teresa Calimeri, MD PhD, Alessandro Re, MD, Jahanzaib Khwaja, Barbara Botto, Claudia Cellini, MD, Luca Nassi, Kim Linton, MBChB PhD, Pam McKay, MD, Jacopo Olivieri, Caterina Patti, MD, Francesca Re, Alessandro Fanni, MD, Vikram Singh, MD, Jacoline Bromberg, MD, Kelly Cozens, Elisabetta Gastaldi, Nicola Cascavilla, Andrew Davies, MD PhD, Christopher P Fox, MBChB(Hons), MRCP, FRCPath, PhD, Maurizio Frezzato, MD, Wendy Osborne, MBBS, Anna Marina Liberati, Urban Novak, Renato Zambello, Emanuele Zucca, MD, Kate Cwynarski, PhDMD
Journal: Blood
Blood (2019) 134 (Supplement_1): 353.
https://doi.org/10.1182/blood-2019-129835
Published: 2019
Journal Articles

Phase 1/2 Study of AUTO3 the First Bicistronic Chimeric Antigen Receptor (CAR) Targeting CD19 and CD22 Followed By an Anti-PD1 in Patients with Relapsed/Refractory (r/r) Diffuse Large B Cell Lymphoma (DLBCL): Results of Cohort 1 and 2 of the Alexander Study

Kirit M. Ardeshna, MBBChir, Maria A V Marzolini, Jane Norman, MD, Muhammad Al-Hajj, Simon Thomas, PhD, Jim Faulkner, Ekaterini Kotsopoulou, Martin Pule, MD, Vijay G R Peddareddigari, Nushmia Z Khokhar, Maud Jonnaert, PhD, Robert Chen, MD, Wendy Osborne, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 246.
https://doi.org/10.1182/blood-2019-122724
Published: 2019
Journal Articles

An International Multicentre Study of Consecutively Diagnosed Patients with ALCL: Outcomes Following First-Line Therapy in Routine Clinical Practice

Nicolas Martinez-Calle, MD MSc, Amy A. Kirkwood, MSc, Maxine Lamb, PhD, Alexandra Smith, PhD, Kate Manos, Caroline Shrubsole, MD, Nicola Gray, Sapna Ladani, MRCP, Katharine Louise Lewis, BMBS, FRCPath, MRCPath, Mark Bishton, Matthew J Ahearne, MDMBBS, Eliza A Hawkes, Wendy Osborne, MD, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Cathy Burton, Christopher P Fox, MBChB(Hons), MRCP, FRCPath, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 2849.
https://doi.org/10.1182/blood-2019-122083
Published: 2019
Journal Articles

Ibrutinib at First Relapse for Mantle Cell Lymphoma: A United Kingdom Real World Analysis of Outcomes in 169 Patients

Rory McCulloch, FRCPath, MRCP, MBBS, Simon Rule, Toby A. Eyre, Harshita Goradia, Simon Bolam, MD, Thomas Creasey, MBBS, David Tucker, MD, Michelle Furtado, Oliver Miles, Samuel Harrison, Amir Shenouda, Andrew Robinson, Matthew Wilson, MD BSc, MRCP, Annabel McMillan, Nimish Shah, Graham McIlroy, MD, David Dutton, MD, Adam Bond, Luke Attwell, Alexander Langridge, Helen Parry, MB ChB, MRCP, PhD, John Willan, Gavin Campbell, FRCP,FRCPath, Deborah Turner, David Lewis, PhD FRCPath, BSc, Helen McCarthy, MBBS, PhD, Jonathan Lambert, Pamela McKay, MD, Neil Phillips, Shankara Paneesha, MD, Wendy Osborne, MD, Mark Bishton, Nicola Crosbie
Journal: Blood
Blood (2019) 134 (Supplement_1): 3993.
https://doi.org/10.1182/blood-2019-125947
Published: 2019
Journal Articles

Procarbazine-Free Escalated Beacopdac in Frontline Therapy of Advanced Hodgkin Lymphoma Reduces Red Cell Transfusion Requirements and May Shorten Time to Menstrual Period Recovery Compared to Escalated Beacopp and Appears to be As Efficacious

Anna Santarsieri, MBBS, Katherine Sturgess, MA, MBBChir, MRCP, MSc, Pauline Brice, Tobias F Menne, MD PhD FRCPath, Wendy Osborne, MD, Thomas Creasey, MBBS, Kirit M. Ardeshna, MA, MD FRCP, FRCPath, Sarah Behan, Stephen Booth, MA,MBBChir,MRCP,FRCPath, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Kate Cwynarski, PhDMD, Sunil Iyengar, MD, Stephen G Jones, Deirdre O'Mahony, MD, Nicolas Martinez-Calle, MD MSc, Pamela McKay, MD, Sateesh K Nagumantry, BM BCh, John Rudge, MA, PhD, Nimish Shah, MD, Gwyneth Stafford, Alexander Sternberg, Benjamin J Uttenthal, MD PhD, Andrew K McMillan, FRCP, George A Follows, MD PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1564.
https://doi.org/10.1182/blood-2019-125256
Published: 2019
Journal Articles

Real-World Data of High-Grade Lymphoma Patients Treated with CD19 CAR-T in England

Andrea Kuhnl, Claire Roddie, PhD MD, Nuria Martinez-Cibrian, Tobias F Menne, MD PhD FRCPath, Kim Linton, MBChB PhD, Sanne Lugthart, Sridhar Chaganti, MDPhDMRCP,FRCPath, Robin Sanderson, MRCP,FRCPath, Maria A V Marzolini, Jane Norman, MD, Wendy Osborne, MD, John Radford, Stephen Robinson, MBBS, PhD BSc, Ram Malladi, Piers E.M. Patten, BSc, MRCP, MRCPath, PhD, Maeve A O'Reilly, MBBCHBAO, Muhammad Saif, MD, Geoff Shenton, Adrian Bloor, FRCPath, Clare J Rowntree, MBBS, PhD FRCP, FRCPath, David A. Irvine, BSc, MBBChir, MRCP, FRCPath, PhD, Orla Stewart, Arzhang Ardavan, Kate Robinson, Antonio Pagliuca, MBBS, MA, FRCP, FRCPath, Kristian M Bowles, MBBS, PhD, Graham P. Collins, MA, MBBS, MRCP, FRCPath, DPhil, Rod Johnson, Andrew K McMillan, FRCP
Journal: Blood
Blood (2019) 134 (Supplement_1): 767.
https://doi.org/10.1182/blood-2019-124177
Published: 2019
Journal Articles

Spirit 2: Final 5 Year Analysis of the UK National Cancer Research Institute Randomized Study Comparing Imatinib with Dasatinib in Patients with Newly Diagnosed Chronic Phase CML

Stephen O'Brien, MBBS, BSc, PhD MRCPath, MRCP, Leanne Cork, BSc, Valeria Bandeira, MD, Ruth Bescoby, MSc, Letizia Foroni, MD PhD, Lynn Alaily, MSc, RN, NDN, MICR, Wendy Osborne, MBBS, Helen Bell-Gorrod, BSc, Nicholas Latimer, PhD, Jane Apperley, MB ChB MD, Corinne Hedgley, BSc (Hons), Richard Syzdlo, PhD, Jennifer Byrne, MB, ChB, MRCP, MRCPath, MD, Christopher Pocock, MD PhD, Bernard Ramsahoye, MB, ChB, PhD FRCPath, MRCP, Thomas Zwingers, BSc, James Wason, PhD, Mhairi Copland, PhD MBBChir, FRCP, FRCPath, Richard Clark, MBBS, MRCP, MRCPath, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 457.
https://doi.org/10.1182/blood-2018-99-110128
Published: 2018