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David Wrench
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Journal Articles

Glofitamab and Epcoritamab in the Real World: A UK Multicentre Retrospective Analysis of Efficacy, Tolerability and Practical Implications

Euan Haynes, Kushani Ediriwickrema, Sarah Lawless, Kevin Joyce, Matthew Wells, Jeffrey Smith, Kim Linton, Anna Santarsieri, George Follows, John Willan, Robert Osborn, Matthew R Wilson, Pamela McKay, Mahina Baloch, Rory McCulloch, Mary Gleeson, David Wrench, David Foldes, Edward Kanfer, Kyaw Zin Maw, Andrea Kuhnl, Matthew Ahearne, Mary Owen, Jane Norman, Ravindu De Silva, Nimish Shah, Harriet Ambrose, Christopher P. Fox, Janine Qasim, Graham P. Collins, Martha Vickers, David Tucker, Li Yuan Chan, Sunil Iyengar, Dima el-Sharkawi, Rebecca Auer, Catherine Cox, Hwai Jing Hiew, Andrew J. Davies, Philippa Kelsey, David John Lewis, Abigail Martin, Gavin Preston, Dominic J. Culligan, Angus Broom, William Wilson, Wendy Osborne, William Townsend
Journal: Blood
Blood (2024) 144 (Supplement 1): 3100.
https://doi.org/10.1182/blood-2024-203781
Published: 2024
Journal Articles

Ibrutinib as part of risk-stratified treatment for posttransplant lymphoproliferative disorder: the phase 2 TIDaL trial

Clinical Trials & Observations
Sridhar Chaganti, Shanna Maycock, Graham McIlroy, Aimee Jackson, Rebecca Bishop, Sarah Johnson, Edward Kanfer, Shireen Kassam, Kate Cwynarski, David Wrench, Arvind Arumainathan, Christopher P. Fox, Rod Johnson, Pam McKay, Shankara Paneesha, Clare Rowntree, Constantine Balotis, Graham P. Collins, Andrew Davies, Josh Wright, Sarah Burns, Arian Laurence, Keith Wheatley, Tobias Menne
Journal: Blood
Blood (2024) 144 (4): 392–401.
https://doi.org/10.1182/blood.2024023847
Published: 2024
Includes: Supplemental data
Journal Articles

Risk-Stratified Sequential Treatment with Ibrutinib and Rituximab (IR) and IR-CHOP for De-Novo Post-Transplant Lymphoproliferative Disorder: Results of the Tidal Trial

Sridhar Chaganti, Shanna Maycock, Graham McIlroy, Waleed A Iqbal, John Mason, Edward Kanfer, Shireen Kassam, Kate Cwynarski, David Wrench, Arvind K. Arumainathan, Christopher P Fox, Rod Johnson, Pam McKay, Shankara Paneesha, Clare J Rowntree, Constantine-George Balotis, Graham P. Collins, Andrew Davies, Josh Wright, Keith Wheatley, Tobias F Menne
Journal: Blood
Blood (2021) 138 (Supplement 1): 2492.
https://doi.org/10.1182/blood-2021-146494
Published: 2021
Journal Articles

A Phase II Study to Determine the Safety and Efficacy of the Dual m-TORC Inhibitor AZD2014 and to Investigate Additional Toxicities in Combination with Rituximab in Relapsed/Refractory Diffuse Large B Cell Lymphoma (DLBCL)

Toby A. Eyre, MBBChir, MRCP, Catherine Hildyard, MRCP, BA, Anesh Panchal, BSc, MSc, Aimee E Houlton, BSc, MSc, Louise Hopkins, BSc, MRes, Angela Hamblin, MD PhD, Kim Linton, MBChB PhD, Andrew Pettitt, FRCPath, PhD, Simon Rule, MD, Kate Cwynarski, PhD MD, Sally Barrington, MBBS, MSc, FRCP, FRCR, MD, David Wrench, MA, MBBChir, FRCPath, PhD, Andrew Davies, PhD, Graham Collins, MD PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5210.
https://doi.org/10.1182/blood.V130.Suppl_1.5210.5210
Published: 2017
Journal Articles

R-GCVP As Second Line Treatment in Elderly Patients with DLBCL Who Fail R-CHOP and Are Not Candidates for Intensive Therapy

Betty Gration, MBBS, Ana Duran, MD, Naheed Mir, BSc, FRCP, FRCPath, Lisa Yuen, MPharm, PgDip, IP, Marcus Warner, MPharm, PG Dip GPP, Karen Stanley, RGN, MSc Advanced Practice, Jessica Brady, MBBCh, FRCR, George Mikhaeel, MB BCh, MSc, FRCR, Paul A Fields, MD PhD, David Wrench, MA, MBBChir, FRCPath, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4133.
https://doi.org/10.1182/blood.V130.Suppl_1.4133.4133
Published: 2017
Journal Articles

Achievement of Complete Hematological Remission and Reversal of High HTLV-1 Viral Loads with Anti CCR-4 Monoclonal Antibody Administration in Afro Caribbean Patients with Relapsed Chronic Adult T Cell Leukaemia (ATLL)

Paul Fields, MD PhD, Maria Demontis, PhD, Lucy Cook, MD PhD, Sasha Marks, MDFRCPath,FRCP, David Wrench, MD PhD, Arief Gunawan, MBChB, MRCP, Claire Woodley, RN, Graham Taylor, MD FRCP
Journal: Blood
Blood (2014) 124 (21): 5474.
https://doi.org/10.1182/blood.V124.21.5474.5474
Published: 2014
Journal Articles

Concurrent Follicular Lymphoma At Diagnosis Has a Negative Impact On The Outcome Of Patients With Diffuse Large B Cell Lymphoma

David Wrench, MD, PhD, Hasan Rizvi, MD, Andrew Wilson, Ciaran O'Riain, MD, PhD, Andrew Clear, Janet Matthews, Daniele Laszlo, MD, T. Andrew Lister, MD, John G. Gribben, MD, DSc, FRCP, FMedSci, FRCPath, Maria Calaminici, MD, PhD, Silvia Montoto, MD
Journal: Blood
Blood (2013) 122 (21): 4260.
https://doi.org/10.1182/blood.V122.21.4260.4260
Published: 2013
Journal Articles

Whole Genome Sequencing in Sequential Biopsies Reveals the Genetic Evolution of Follicular Lymphoma to Transformed Follicular Lymphoma

Jessica Okosun, MD, Csaba Bödör, PhD, Jun Wang, PhD, Shamzah Araf, MD, Jacek Marzec, PhD, Sameena Iqbal, Janet Matthews, Maria Calaminici, MD, Ciaran O'Riain, MD, PhD, Derville O'Shea, MD, PhD, Emanuela Carlotti, PhD, Andrew Davies, MD, David Wrench, MD, PhD, András Matolcsy, MD, PhD, T. Andrew Lister, MD, John G Gribben, Silvia Montoto, MD, Claude Chelala, PhD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2012) 120 (21): 145.
https://doi.org/10.1182/blood.V120.21.145.145
Published: 2012
Journal Articles

SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma

Brief Report
David Wrench, Pamela Leighton, Christine F. Skibola, Lucia Conde, Jean-Baptiste Cazier, Janet Matthews, Sameena Iqbal, Emanuela Carlotti, Csaba Bödör, Silvia Montoto, Maria Calaminici, John G. Gribben, T. Andrew Lister, Jude Fitzgibbon
Journal: Blood
Blood (2011) 117 (11): 3147–3150.
https://doi.org/10.1182/blood-2010-10-315382
Published: 2011
Includes: Supplemental data
Journal Articles

TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma

David Wrench, Ajanthah Sangaralingam, Hira Tayyib, Myung-Kuk Kang, Ciaran O'Riain, Manu Gupta, Emanuela Carlotti, PhD, BSc, Csaba Bodor, Sameena Iqbal, Tracy Chaplin, Janet Matthews, Andrew James Clear, BSc, Andrew Davies, Silvia Montoto, MD, Maria Calaminici, Bryan D Young, BSc, PhD, John G. Gribben, MD, DSc, Andrew Lister, MD, Jude Fitzgibbon
Journal: Blood
Blood (2010) 116 (21): 799.
https://doi.org/10.1182/blood.V116.21.799.799
Published: 2010
Journal Articles

Transformation of follicular lymphoma to diffuse large B-cell lymphoma may occur by divergent evolution from a common progenitor cell or by direct evolution from the follicular lymphoma clone

Brief Report
Emanuela Carlotti, David Wrench, Janet Matthews, Sameena Iqbal, Andrew Davies, Andrew Norton, Jason Hart, Raymond Lai, Silvia Montoto, John G. Gribben, T. Andrew Lister, Jude Fitzgibbon
Journal: Blood
Blood (2009) 113 (15): 3553–3557.
https://doi.org/10.1182/blood-2008-08-174839
Published: 2009
Includes: Supplemental data
Journal Articles

Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation

Brief Report
Derville O'Shea, Ciarán O'Riain, Manu Gupta, Rachel Waters, Youwen Yang, David Wrench, John Gribben, Andreas Rosenwald, German Ott, Lisa M. Rimsza, Harald Holte, Jean-Baptiste Cazier, Nathalie A. Johnson, Elias Campo, Wing C. Chan, Randy D. Gascoyne, Bryan D. Young, Louis M. Staudt, T. Andrew Lister, Jude Fitzgibbon
Journal: Blood
Blood (2009) 113 (10): 2298–2301.
https://doi.org/10.1182/blood-2008-08-174953
Published: 2009
Includes: Supplemental data
Journal Articles

Molecular Signatures Implicate Innate Immune Cells, Fibrosis, and Angiogenesis in Survival Following R-CHOP Treatment of Diffuse Large B Cell Lymphoma

Georg Lenz, George Wright, Ph.D., Sandeep Dave, Wenming Xiao, John Powell, Hong Zhao, Weihong Xu, Bruce Tan, Neta Goldschmidt, Javeed Iqbal, Ph.D., Julie Vose, Martin A Bast, Kai Fu, Dennis D. Weisenburger, Timothy C. Greiner, James O. Armitage, Alastair Kyle, Lorraine May, Randy D. Gascoyne, Joseph M. Connors, Gunhild Troen, Harald Holte, Stein Kvaloy, Daan Dierickx, Gregor Verhoef, Jan Delabie, Erlend B. Smeland, Pedro Jares, Antonio Martinez, Armando Lopez-Guillermo, Emili Montserrat, Elias Campo, Rita M. Braziel, Thomas P. Miller, Lisa M. Rimsza, James R. Cook, Brad Pohlman, MD, John William Sweetenham, Raymond R. Tubbs, Richard I. Fisher, Elena Hartmann, Andreas Rosenwald, German Ott, Hans- Konrad Muller-Hermelink, David Wrench, T. Andrew Lister, Elaine S. Jaffe, Wyndham Wilson, Wing C. Chan, Louis M. Staudt, MD.
Journal: Blood
Blood (2008) 112 (11): 475.
https://doi.org/10.1182/blood.V112.11.475.475
Published: 2008
Journal Articles

Determining the Mechanism of Transformation of Follicular Lymphoma into Diffuse Large B Cell Lymphoma.

Emanuela Carlotti, PhD, David Wrench, MD, Sameena Iqbal, BSc, Derville O’Shea, MD, Andrew Davies, MD, PhD, Priya Virappane, BSc, Jason Hart, MD, Raymond Lai, MD, PhD, John G. Gribben, MD, DSc, Andrew T. Lister, MD, Jude Fitzgibbon, PhD
Journal: Blood
Blood (2007) 110 (11): 181.
https://doi.org/10.1182/blood.V110.11.181.181
Published: 2007
Journal Articles

Pathologic Features May Predict the Clinical Outcome of Hepatic Graft Versus Host Disease (H-GVHD).

Rafael F. Duarte, Julio Delgado-Gonzalez, Bronwen E. Shaw, David Wrench, Mark Ethell, David Patch, Amar P. Dhillon, Stephen Mackinnon, Michael Potter, Alberto F. Quaglia
Journal: Blood
Blood (2004) 104 (11): 5079.
https://doi.org/10.1182/blood.V104.11.5079.5079
Published: 2004