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Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Blood (2015) 126 (23): 365.

https://doi.org/10.1182/blood.V126.23.365.365

Published: 2015

Journal Articles

SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction

Essam Ghazaly, MD PhD, Paul Smith, PhD, Chathunissa Gnanaranjan, MSc, Bryan D Young, BSc, PhD, Simon Joel, PhD, John G. Gribben, MD DSc, David C Taussig, PhD MRCP, FRCPath

Blood (2014) 124 (21): 5324.

https://doi.org/10.1182/blood.V124.21.5324.5324

Published: 2014

Journal Articles

Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia

Floriana Manodoro, Jacek Marzec, Tracy Chaplin, Farideh Miraki-Moud, Eva Moravcsik, Jelena V. Jovanovic, Jun Wang, Sameena Iqbal, David Taussig, David Grimwade, John G. Gribben, Bryan D. Young, Silvana Debernardi

Blood (2014) 123 (13): 2066–2074.

https://doi.org/10.1182/blood-2012-12-469833

Published: 2014

Includes: Supplemental data

Journal Articles

Clonal Progression Including Evolution Of An iAMP21 Chromosome In Xenograft Models Of BCP-ALL

Paul B Sinclair, PhD, Lars Buechler, PhD, Joanna Cheng, MSc, Jake Clayton, MRes, Claire Schwab, BSc, Lisa Jones, BSc, Helen Blair, PhD, Lisa J Russell, PhD, Bryan D Young, BSc, PhD, Olaf Heidenreich, PhD, Christine J Harrison, PhD

Blood (2013) 122 (21): 2485.

https://doi.org/10.1182/blood.V122.21.2485.2485

Published: 2013

Journal Articles

Loss of Imprinting at the 14q32 Domain Leads to MicroRNA Overexpression in Acute Promyelocytic Leukemia

Floriana Manodoro, PhD, Jacek Marzec, Jun Wang, PhD, Tracy Chaplin, Jelena V Jovanovic, Moravcsik Eva, Iqbal Sameena, David Grimwade, MD, PhD, John Gribben, MD, DSc, Bryan D Young, BSc, PhD, Silvana Debernardi, PhD

Blood (2013) 122 (21): 2494.

https://doi.org/10.1182/blood.V122.21.2494.2494

Published: 2013

Journal Articles

The Correlation Between Deletion Architecture, ATM Mutational Status and BIRC3 Disruption in 11q-Deleted CLL

Matthew JJ Rose-Zerilli, PhD, Jade Forster, Helen Parker, PhD, Anton Parker, Ana E Rodríguez, Tracy Chaplin, Anne Gardiner, Andrew Collins, PhD, Bryan D Young, PhD, Tatjana Stankovic, MD., PhD, David Oscier, MD, Jonathan C. Strefford, BSc, PhD

Blood (2012) 120 (21): 658.

https://doi.org/10.1182/blood.V120.21.658.658

Published: 2012

Journal Articles

Clonal Evolution of Multiple TET2 mutations In the Transformation of Chronic Myelomonocytic Leukemia to Acute Myeloid Leukemia and Its Subsequent Relapse

Robert D. Petty, BSc, Farideh Miraki-Moud, Tracy Chaplin, Grossmann Vera, Daverio Andrea, Finlay Macdougall, Maria Ronayne, Bryan D Young, BSc, PhD, Manoj Raghavan, MBBS, PhD

Blood (2010) 116 (21): 2699.

https://doi.org/10.1182/blood.V116.21.2699.2699

Published: 2010

Journal Articles

Sequential SNP6.0 Microarray Analysis In Rai Stage 0 CLL Patients with Either Stable or Progressive Identifies Genomic Evolution In Both Cohorts

Matthew JJ Rose-Zerilli, PhD, Miqdad Rajibali, BSc, Helen Parker, PhD, Anton Parker, BSc, Anne Catherine Gardiner, BSc, Zadie Davis, PhD, Sarah Mold, BSc, Sharron Glide, BSc, Tracy Chaplin, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD

Blood (2010) 116 (21): 1696.

https://doi.org/10.1182/blood.V116.21.1696.1696

Published: 2010

Journal Articles

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

Blood (2010) 116 (21): 1665.

https://doi.org/10.1182/blood.V116.21.1665.1665

Published: 2010

Journal Articles

Genome Wide Study of DNA Methylation In AML

Marwa Saied, MBCHB, MD, Sabah Khaled, PhD, Thomas Down, PhD, Jacek Marzec, PhD, Paul Smith, PhD, Silvana Debernardi, PhD, BSc, Bryan D Young, BSc, PhD

Blood (2010) 116 (21): 3618.

https://doi.org/10.1182/blood.V116.21.3618.3618

Published: 2010

Journal Articles

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

Helen Parker, PhD, Matthew JJ Rose-Zerilli, PhD, Anton Parker, BSc, Tracy Chaplin, Anne Catherine Gardiner, BSc, Mike Griffiths, Andrew Collins, PhD, Bryan D Young, BSc, PhD, David Graham Oscier, Jonathan C. Strefford, BSc, PhD

Blood (2010) 116 (21): 757.

https://doi.org/10.1182/blood.V116.21.757.757

Published: 2010

Journal Articles

TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma

David Wrench, Ajanthah Sangaralingam, Hira Tayyib, Myung-Kuk Kang, Ciaran O'Riain, Manu Gupta, Emanuela Carlotti, PhD, BSc, Csaba Bodor, Sameena Iqbal, Tracy Chaplin, Janet Matthews, Andrew James Clear, BSc, Andrew Davies, Silvia Montoto, MD, Maria Calaminici, Bryan D Young, BSc, PhD, John G. Gribben, MD, DSc, Andrew Lister, MD, Jude Fitzgibbon

Blood (2010) 116 (21): 799.

https://doi.org/10.1182/blood.V116.21.799.799

Published: 2010

Journal Articles

Discovery and Quantification of Small RNA Molecules In Acute Myeloid Leukaemia Using Solexa High-Throughput Clonal Sequencing

Silvana Debernardi, PhD, BSc, Jacek Marzec, BSc, PhD, Floriana Manodoro, BSc, PhD, Richard Dobson, BSc, Charles Mein, BSc, Alessandra Curtotti, BSc, Michael Mitchell, BSc, PhD, Bryan D Young, BSc, PhD

Blood (2010) 116 (21): 847.

https://doi.org/10.1182/blood.V116.21.847.847

Published: 2010

Journal Articles

Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia

Caroline M. Bateman, Susan M. Colman, Tracy Chaplin, Bryan D. Young, Tim O. Eden, Manoo Bhakta, Eric J. Gratias, Elisabeth R. van Wering, Giovanni Cazzaniga, Christine J. Harrison, Richard Hain, Philip Ancliff, Anthony M. Ford, Lyndal Kearney, Mel Greaves

Blood (2010) 115 (17): 3553–3558.

https://doi.org/10.1182/blood-2009-10-251413

Published: 2010

Includes: Supplemental data

Journal Articles

Genome-Wide Micro-Deletions and Amplifications Acquired at Relapse in Acute Myeloid Leukemia.

Manoj Raghavan, MBBS, PhD, MRCP, FRCPath, Manu Gupta, PhD, Tracy Chaplin, MSc, Sabah Khalid, PhD, T. Andrew Lister, Bryan D Young, PhD

Blood (2009) 114 (22): 166.

https://doi.org/10.1182/blood.V114.22.166.166

Published: 2009

Journal Articles

Relapsed Childhood High Hyperdiploid Acute Lymphoblastic Leukemia: Genome-Wide Screening Reveals the Presence of Preleukemic Ancestral Clones and the Secondary Nature of Microdeletions and RTK-RAS Mutations.

Josef Davidsson, PhD, Kajsa Paulsson, PhD, David Lindgren, PhD, Henrik Lilljebjörn, MS, Tracy Chaplin, MS, Erik Forestier, MD, PhD, Mette K Andersen, MD, PhD, Ann Nordgren, MD, PhD, Richard Rosenquist, MD, PhD, Thoas Fioretos, MD, PhD, Bryan D Young, PhD, Bertil Johansson, MD, PhD

Blood (2009) 114 (22): 2591.

https://doi.org/10.1182/blood.V114.22.2591.2591

Published: 2009

Journal Articles

13q Deletion Size Predicts Disease Progression and Response to Treatment in Patients with Chronic Lymphocytic Leukaemia.

Jonathan C Strefford, PhD, Helen Parker, PhD, Anton Parker, BSc, Hazel Robinson, PhD, Tracy Chaplin, MSc, Xiao-He Chen, PhD, David Bunyan, PhD, Anne Gardiner, BSc, Bryan D Young, PhD, David Graham Oscier, MD

Blood (2009) 114 (22): 671.

https://doi.org/10.1182/blood.V114.22.671.671

Published: 2009

Journal Articles

Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation

Blood (2009) 113 (10): 2298–2301.

https://doi.org/10.1182/blood-2008-08-174953

Published: 2009

Includes: Supplemental data

Journal Articles

Specific JAK2 mutation ( JAK2 R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia

Lyndal Kearney, David Gonzalez De Castro, Jenny Yeung, Julia Procter, Sharon W. Horsley, Minenori Eguchi-Ishimae, Caroline M. Bateman, Kristina Anderson, Tracy Chaplin, Bryan D. Young, Christine J. Harrison, Helena Kempski, Chi Wai E. So, Anthony M. Ford, Mel Greaves

Blood (2009) 113 (3): 646–648.

https://doi.org/10.1182/blood-2008-08-170928

Published: 2009

Includes: Supplemental data

Journal Articles

Sequence of Genetic Events in ETV6-RUNX1 Positive B Precursor ALL: Insights from Identical Twins with Concordant Leukaemia

Caroline M Bateman, MBBS, MRCP, Sharon W. Horsley, Tracy Chaplin, Bryan D Young, Anthony M Ford, Lyndal Kearney, Mel Greaves

Blood (2008) 112 (11): 2.

https://doi.org/10.1182/blood.V112.11.2.2

Published: 2008

NARROW

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

SKIP Is Underexpressed in AML Leading to Sphingosine Kinase Hypofunction

Loss of imprinting at the 14q32 domain is associated with microRNA overexpression in acute promyelocytic leukemia

Clonal Progression Including Evolution Of An iAMP21 Chromosome In Xenograft Models Of BCP-ALL

Loss of Imprinting at the 14q32 Domain Leads to MicroRNA Overexpression in Acute Promyelocytic Leukemia

The Correlation Between Deletion Architecture, ATM Mutational Status and BIRC3 Disruption in 11q-Deleted CLL

Clonal Evolution of Multiple TET2 mutations In the Transformation of Chronic Myelomonocytic Leukemia to Acute Myeloid Leukemia and Its Subsequent Relapse

Sequential SNP6.0 Microarray Analysis In Rai Stage 0 CLL Patients with Either Stable or Progressive Identifies Genomic Evolution In Both Cohorts

The Interlaboratory RObustness of Next-Generation Sequencing (IRON) Study: Deep-Sequencing Investigating TET2 , CBL , and KRAS Mutations In 4464 Amplicons by An International Group Involving 8 Laboratories.

Genome Wide Study of DNA Methylation In AML

Deletion Size Influences Clinical Outcome In Patients with Chronic Lymphocytic Leukemia; 13q Deletion Anatomy, Cooperating Lesions and Cancer Pathogenesis

TNFRSF14 and EZH2 Mutations, Chr2p Gain and Copy Number Changes Targeting Genes Whose Proteins Interact with the Microenvironment In Transformed Follicular Lymphoma

Discovery and Quantification of Small RNA Molecules In Acute Myeloid Leukaemia Using Solexa High-Throughput Clonal Sequencing

Acquisition of genome-wide copy number alterations in monozygotic twins with acute lymphoblastic leukemia

Genome-Wide Micro-Deletions and Amplifications Acquired at Relapse in Acute Myeloid Leukemia.

Relapsed Childhood High Hyperdiploid Acute Lymphoblastic Leukemia: Genome-Wide Screening Reveals the Presence of Preleukemic Ancestral Clones and the Secondary Nature of Microdeletions and RTK-RAS Mutations.

13q Deletion Size Predicts Disease Progression and Response to Treatment in Patients with Chronic Lymphocytic Leukaemia.

Regions of acquired uniparental disomy at diagnosis of follicular lymphoma are associated with both overall survival and risk of transformation

Specific JAK2 mutation ( JAK2 R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia

Sequence of Genetic Events in ETV6-RUNX1 Positive B Precursor ALL: Insights from Identical Twins with Concordant Leukaemia

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American Society of Hematology

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