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Stuart Blakemore
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Journal Articles

Extracellular vesicles and PD-L1 suppress macrophages, inducing therapy resistance in TP53 -deficient B-cell malignancies

Elena Izquierdo, Daniela Vorholt, Stuart Blakemore, Benedict Sackey, Janica L. Nolte, Verena Barbarino, Jan Schmitz, Nadine Nickel, Daniel Bachurski, Liudmila Lobastova, Milos Nikolic, Michael Michalik, Reinhild Brinker, Olaf Merkel, Marek Franitza, Theodoros Georgomanolis, René Neuhaus, Maximilian Koch, Niklas Nasada, Gero Knittel, Björn Chapuy, Nicole Ludwig, Eckart Meese, Lukas Frenzel, Hans Christian Reinhardt, Martin Peifer, Rocio Rebollido-Rios, Heiko Bruns, Marcus Krüger, Michael Hallek, Christian P. Pallasch
Journal: Blood
Blood (2022) 139 (25): 3617–3629.
https://doi.org/10.1182/blood.2021014007
Published: 2022
Includes: Supplemental data
Journal Articles

DNA Damage-Response Pathway in Lymphoma Determines Interactions with Macrophages By Altered PD-L1 Expression and Exosome Formation

Daniela Vorholt, PhD, Elena Izquierdo-Alvarez, PhD, Benedict Sackey, Jan Schmitz, Nadine Nickel, PhD, Stuart Blakemore, PhD, Gero Knittel, MSc, Christian Reinhardt, MD, Clemens-Martin Wendtner, Heiko Bruns, PhD, Michael Hallek, Christian Pallasch, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 275.
https://doi.org/10.1182/blood-2018-99-120264
Published: 2018
Journal Articles

The Contribution of Gene Mutations to Long-Term Clinical Outcomes: Data from the Randomised UK LRF CLL4 Trial

Stuart Blakemore, PhD, Ruth Clifford, Pavlos Antoniou, Helen Parker, PhD, Pauline Robbe, MSc, Marta Larrayoz, PhD, Zadie Davis, Latha Kadalyayil, Andrew Collins, Jade Forster, PhD, Monica Else, Andrew J Steele, PhD, Jacqueline Chan, PhD, Graham Speight, PhD, Mark Cragg, PhD, Matthew John Jerome Rose-Zerilli, PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Anna Schuh, MD PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 259.
https://doi.org/10.1182/blood.V130.Suppl_1.259.259
Published: 2017
Journal Articles

Clinical Importance of DNA Methylation Signatures in Chronic Lymphocytic Leukaemia Patients Treated with Chemo-Immunotherapy

Harindra Amarasinghe, PhD, Tomasz K Wojdacz, PhD MSc, Matthew John Jerome Rose-Zerilli, PhD, Alice Beattie, Jade Forster, PhD, Latha Kadalayil, Stuart Blakemore, PhD, Helen Parker, PhD, Marta Larrayoz, PhD, Ruth Clifford, Zadie Davis, Monica Else, Dena Cohen, Andrew J Steele, PhD, Richard Rosenquist, MD PhD, Andrew Collins, Andrew Pettitt, FRCPath, PhD, Peter Hillmen, MBChB, PhD, Pauline Robbe, MSc, Christopher Plass, Anna Schuh, MD PhD, Daniel Catovsky, MD FRCP, David Oscier, MD PhD, Christopher C. Oakes, PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 56.
https://doi.org/10.1182/blood.V130.Suppl_1.56.56
Published: 2017
Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Matthew John Jerome Rose-Zerilli, PhD, Helen Parker, Marta Larrayoz, PhD, Ruth Clifford, Stuart Blakemore, Jennifer Edelmann, MD, Jane Gibson, Jun Wang, Viktor Ljungstrom, Tracy Chaplin, Ali Roghanian, Zadie Davis, Anton Parker, BSc, Eugen Tausch, MD, Stavroula Ntoufa, Sara Ramos, Pauline Robbe, MSc, Andrew J Steele, PhD, Graham Packham, PhD, Ana E. Rodriguez, Lee Brown, Feargal McNicholl, Francesco Forconi, MD DM, PhD FRCPath, Andrew R Pettitt, MRCP PhD, Peter Hillmen, Martin J.S. Dyer, Prof., Mark S Cragg, PhD, Bryan D Young, BSc, PhD, Claude Chelala, Richard Rosenquist, Kostas Stamatopoulos, MD, Stephan Stilgenbauer, Samantha Knight, Anna Schuh, MD PhD, David Oscier, Jonathan C Strefford, PhD
Journal: Blood
Blood (2015) 126 (23): 365.
https://doi.org/10.1182/blood.V126.23.365.365
Published: 2015
Journal Articles

EGR2 Mutations in Chronic Lymphocytic Leukemia: A New Bad Player

Daniel Noerenberg*, Emma Young*, Viktor Ljungström, Larry Mansouri, Karla Plevova, Panagiotis Baliakas, Stuart Blakemore, Davide Rossi, MD PhD, Ruth Clifford, Veronika Navrkalova, PhD, Lesley-Ann Sutton, Karin E Smedby, MD PhD, Gunnar Juliusson, Chrysoula Belessi, Panagiotis Panagiotidis, Nicholas Chiorazzi, MD, Frederic Davi, Anton W. Langerak, Anna Schuh, MD PhD, Gianluca Gaidano, MD PhD, Jonathan C Strefford, PhD, Paolo Ghia, Kostas Stamatopoulos, Sarka Pospisilova, Thorsten Zenz, Richard Rosenquist**, Frederik Damm**
Journal: Blood
Blood (2015) 126 (23): 4126.
https://doi.org/10.1182/blood.V126.23.4126.4126
Published: 2015
Journal Articles

Splicing Inhibition By Spliceostatin_A Is a Promising Therapeutic Strategy in Chronic Lymphocytic Leukaemia

Marta Larrayoz, PhD, Stuart Blakemore, Rachel Dobson, BSc, Matthew Rose-Zerilli, PhD, Renata Walewska, Matthew Blunt, PhD, Minoru Yoshida, PhD, David G Oscier, MD, Mark Cragg, PhD, Andrew J Steele, PhD, Jonathan C Strefford, PhD
Journal: Blood
Blood (2014) 124 (21): 3301.
https://doi.org/10.1182/blood.V124.21.3301.3301
Published: 2014