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Journal Articles

Molecular and Functional Profiling of Microenvironmental Interactions in Splenic Marginal Zone Lymphoma

Marina Gerousi, Anastasia Iatrou, Antonios Mingos, Nikolaos Pechlivanis, Stavroula Ntoufa, Maria Gounari, Nikos Papakonstantinou, Georgios Karakatsoulis, Eleni Kotroni, Ioannis Sarrigeorgiou, Zadie Davis, Peggy Lymberi, David Oscier, Ioanna Sakellari, Alexandra Traverse-Glehen, Niki Stavroyianni, Fotis Psomopoulos, Marta Muzio, Paolo Ghia, Anastasia Chatzidimitriou, Kostas Stamatopoulos
Journal: Blood
Blood (2022) 140 (Supplement 1): 9294–9295.
https://doi.org/10.1182/blood-2022-168728
Published: 2022
Journal Articles

Functional Calcitriol/Vitamin D Receptor Signaling in Chronic Lymphocytic Leukemia

Marina Gerousi, Fotis Psomopoulos, Kostantia Kotta, Niki Stavroyianni, Achilles Anagnostopoulos, Ioannis Kotsianidis, Stavroula Ntoufa, Kostas Stamatopoulos
Journal: Blood
Blood (2019) 134 (Supplement_1): 3019.
https://doi.org/10.1182/blood-2019-127910
Published: 2019
Journal Articles

Detailed Functional Characterization of Splenic Marginal Zone Lymphoma: Uncovering Links between the Epigenetic and the Signaling Machinery

Stavroula Ntoufa, Maria Gounari, Nikos Papakonstantinou, Despoina Binou, Ioannis Tyritidis, Theodora Stivarou, Ioannis Sarrigeorgiou, Anastasia Iatrou, Niki Stavroyianni, Achilles Anagnostopoulos, Peggy Lymberi, Kostas Stamatopoulos
Journal: Blood
Blood (2019) 134 (Supplement_1): 1512.
https://doi.org/10.1182/blood-2019-127909
Published: 2019
Journal Articles

RPS15 mutations Repress mRNA Translation in Chronic Lymphocytic Leukemia Cells

Stavroula Ntoufa, Stamatia Laidou, Fotis Psomopoulos, Marina Gerousi, Larry Mansouri, Georgios Tsiolas, Nikos Papakonstantinou, Achilles Anagnostopoulos, Niki Stavroyianni, Antonios M. Makris, Anastasia Hadzidimitriou, PhD, Richard Rosenquist, MD PhD, Kostas Stamatopoulos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 1843.
https://doi.org/10.1182/blood-2018-99-118150
Published: 2018
Journal Articles

The Transcription Factor TAp63 Exerts Pro-Survival Effects in Chronic Lymphocytic Leukemia Acting through the BCL2 Pathway

Stamatia Laidou, Stavroula Ntoufa, Sofia Papanikolaou, Konstantia Kotta, Maria Koutroumani, Theodoros Moysiadis, Achilles Anagnostopoulos, Anastasia Kouvatsi, Niki Stavroyianni, Anastasia Hadzidimitriou, PhD, Antonios M. Makris, Nikos Papakonstantinou, Kostas Stamatopoulos, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 3110.
https://doi.org/10.1182/blood-2018-99-118167
Published: 2018
Journal Articles

Genome-Wide DNA Methylation Profiling of Chronic Lymphocytic Leukemia Subsets Carrying Stereotyped B Cell Receptors

Richard Rosenquist, MD PhD, Larry Mansouri, Sujata Bhoi, Giancarlo Castellano, PhD, Lesley Ann Sutton, PhDBSc, Nikos Papakonstantinou, Ana Queirós, MSc, Panagiotis Baliakas, MD PhD, Sara Ek, PhD, Venera Kuci Emruli, Karla Plevova, PhD, Stavroula Ntoufa, Zadie Davis, Emma Young, Hanna Goransson-Kultima, Anders Isaksson, Karin E Smedby, MD PhD, Gianluca Gaidano, MD PhD, Anton W Langerak, Frederic Davi, Davide Rossi, MD PhD, David Oscier, MD PhD, Sarka Pospisilova, MD PhD, Paolo Ghia, MD PhD, Elias Campo, MD PhD, Kostas Stamatopoulos, Inaki Martin Subero, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 57.
https://doi.org/10.1182/blood.V130.Suppl_1.57.57
Published: 2017
Journal Articles

External Stimuli Modulate EZH2 Expression in Chronic Lymphocytic Leukemia. Rationale and Evidence for Synergistic Anti-Tumor Effects of B Cell Signaling and EZH2 Inhibitors

Elisavet Chartomatsidou, Stavroula Ntoufa, Konstantia Kotta, Marianna Akritidou, Theoni Trangas, Niki Stavroyianni, Achilles Anagnostopoulos, Richard Rosenquist, MD PhD, Paolo Ghia, Nikos Papakonstantinou, Kostas Stamatopoulos
Journal: Blood
Blood (2017) 130 (Supplement 1): 4295.
https://doi.org/10.1182/blood.V130.Suppl_1.4295.4295
Published: 2017
Journal Articles

Longitudinal Assessment of CLL Patients Under Ibrutinib Treatment Reveals Maintained Capacity to Respond to Microenvironmental Stimuli through the Toll-like Receptors

Maria Gounari, PhD, Stavroula Ntoufa, PhD, Konstantia Kotta, PhD, Maria Giovanna Vilia, Athanasia Nenou, Marina Gerousi, Lydia Scarfò, MD, Aliki Xochelli, MD PhD, Eleonora Fonte, PhD, Marta Coscia, MD PhD, Alessandra Tedeschi, Niki Stavroyianni, MD, Marta Muzio, PhD, Kostas Stamatopoulos, MD PhD, Paolo Ghia
Journal: Blood
Blood (2016) 128 (22): 2025.
https://doi.org/10.1182/blood.V128.22.2025.2025
Published: 2016
Journal Articles

Whole-exome sequencing in relapsing chronic lymphocytic leukemia: clinical impact of recurrent RPS15 mutations

Viktor Ljungström, Diego Cortese, Emma Young, Tatjana Pandzic, Larry Mansouri, Karla Plevova, Stavroula Ntoufa, Panagiotis Baliakas, Ruth Clifford, Lesley-Ann Sutton, Stuart J. Blakemore, Niki Stavroyianni, Andreas Agathangelidis, Davide Rossi, Martin Höglund, Jana Kotaskova, Gunnar Juliusson, Chrysoula Belessi, Nicholas Chiorazzi, Panagiotis Panagiotidis, Anton W. Langerak, Karin E. Smedby, David Oscier, Gianluca Gaidano, Anna Schuh, Frederic Davi, Christiane Pott, Jonathan C. Strefford, Livio Trentin, Sarka Pospisilova, Paolo Ghia, Kostas Stamatopoulos, Tobias Sjöblom, Richard Rosenquist
Journal: Blood
Blood (2016) 127 (8): 1007–1016.
https://doi.org/10.1182/blood-2015-10-674572
Published: 2016
Includes: Supplemental data
Journal Articles

Genomic Disruption of the Histone Methyltransferase SETD2 in Chronic Lymphocytic Leukemia

Matthew John Jerome Rose-Zerilli, PhD, Helen Parker, Marta Larrayoz, PhD, Ruth Clifford, Stuart Blakemore, Jennifer Edelmann, MD, Jane Gibson, Jun Wang, Viktor Ljungstrom, Tracy Chaplin, Ali Roghanian, Zadie Davis, Anton Parker, BSc, Eugen Tausch, MD, Stavroula Ntoufa, Sara Ramos, Pauline Robbe, MSc, Andrew J Steele, PhD, Graham Packham, PhD, Ana E. Rodriguez, Lee Brown, Feargal McNicholl, Francesco Forconi, MD DM, PhD FRCPath, Andrew R Pettitt, MRCP PhD, Peter Hillmen, Martin J.S. Dyer, Prof., Mark S Cragg, PhD, Bryan D Young, BSc, PhD, Claude Chelala, Richard Rosenquist, Kostas Stamatopoulos, MD, Stephan Stilgenbauer, Samantha Knight, Anna Schuh, MD PhD, David Oscier, Jonathan C Strefford, PhD
Journal: Blood
Blood (2015) 126 (23): 365.
https://doi.org/10.1182/blood.V126.23.365.365
Published: 2015
Journal Articles

Chystallographic Evidence of Autologous Recognition By a Clonotypic B Cell Receptor in Chronic Lymphocytic Leukemia

Maria Gounari, PhD, Claudia Minici, PhD, Marcus Dühren-von Minden, Schneider Dunja, Alkhatib Alabbas, Übelhart Rudolf, Andreas Agathangelidis, Stavroula Ntoufa, Nicholas Chiorazzi, MD, Hassan Jumaa, Kostas Stamatopoulos, Massimo Degano, Paolo Ghia, MD PhD
Journal: Blood
Blood (2015) 126 (23): 4129.
https://doi.org/10.1182/blood.V126.23.4129.4129
Published: 2015
Journal Articles

Tp63 Contributes to the Apoptosis Resistant Phenotype in Aggressive Chronic Lymphocytic Leukemia

Stavroula Ntoufa, Nikos Papakonstantinou, Despoina Papazoglou, Maria Tsagiopoulou, Sarka Pospisilova, Achilles Anagnostopoulos, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos
Journal: Blood
Blood (2015) 126 (23): 4142.
https://doi.org/10.1182/blood.V126.23.4142.4142
Published: 2015
Journal Articles

ATM Mutations in Major Stereotyped CLL Subsets: Enrichment in Subset #2 is Associated with Unfavourable Outcome

Veronika Navrkalova, PhD, Emma Young, Panagiotis Baliakas, Lenka Radova, Karla Plevova, PhD, Lesley-Ann Sutton, Larry Mansouri, Viktor Ljungstrom, Stavroula Ntoufa, Zadie Davis, Gunnar Juliusson, MD PhD, Karin E Smedby, MD PhD, Chrysoula Belessi, Panagiotis Panagiotidis, Frederic Davi, MD PhD, Anton W. Langerak, Paolo Ghia, MD PhD, Jonathan C Strefford, PhD, David G Oscier, Kostas Stamatopoulos, Sarka Pospisilova, Richard Rosenquist, Martin Trbusek, PhD
Journal: Blood
Blood (2015) 126 (23): 1712.
https://doi.org/10.1182/blood.V126.23.1712.1712
Published: 2015
Journal Articles

Excessive antigen reactivity may underlie the clinical aggressiveness of chronic lymphocytic leukemia stereotyped subset #8

Maria Gounari, Stavroula Ntoufa, Benedetta Apollonio, Nikos Papakonstantinou, Maurilio Ponzoni, Charles C. Chu, Davide Rossi, Gianluca Gaidano, Nicholas Chiorazzi, Kostas Stamatopoulos, Paolo Ghia
Journal: Blood
Blood (2015) 125 (23): 3580–3587.
https://doi.org/10.1182/blood-2014-09-603217
Published: 2015
Includes: Supplemental data
Journal Articles

Overexpression of the Histone Methyltransferase ΕΖΗ2 in Chronic Lymphocytic Leukemia Confers Protection from Apoptosis and Is Linked to Clinical Aggressiveness

Nikos Papakonstantinou, Stavroula Ntoufa, Elisavet Chartomatsidou, Andreas Agathangelidis, Tzeni Karamanli, Achilles Anagnostopoulos, Paolo Ghia, Richard Rosenquist, Chrysoula Belessi, Kostas Stamatopoulos
Journal: Blood
Blood (2014) 124 (21): 1956.
https://doi.org/10.1182/blood.V124.21.1956.1956
Published: 2014
Journal Articles

B-Cell Anergy Underlies Indolent Clinical Behavior Of CLL Stereotyped Subset #4

Stavroula Ntoufa, Nikos Papakonstantinou, Benedetta Apollonio, Maria Gounari, Achilles Anagnostopoulos, MD, Chrysoula Belessi, Marta Muzio, Paolo Ghia, MD, PhD, Kostas Stamatopoulos
Journal: Blood
Blood (2013) 122 (21): 4115.
https://doi.org/10.1182/blood.V122.21.4115.4115
Published: 2013
Journal Articles

Promiscuous Antigen Reactivity May Underlie Clinical Aggressiveness and Increased Risk for Richter's Syndrome in Chronic Lymphocytic Leukemia with Stereotyped IGHV4-39/IGKV1(D)-39 B Cell Receptors

Maria Gounari, Stavroula Ntoufa, Charles C. Chu, PhD, Athanasios Tsaftaris, Nicholas Chiorazzi, MD, Kostas Stamatopoulos, Paolo Ghia
Journal: Blood
Blood (2012) 120 (21): 561.
https://doi.org/10.1182/blood.V120.21.561.561
Published: 2012
Journal Articles

The Mir17∼92 Cluster Is an Immunomodulator in CLL Regulating Distinct Functional Responses to Toll-Like Receptors in Subsets with Stereotyped Antigen Receptors

Stavroula Ntoufa, Nikos Papakonstantinou, Christos Nikolaou, Elisavet Chartomatzidou, Tasoula Touloumenidou, Achilles Anagnostopoulos, Marta Muzio, Paolo Ghia, Chrysoula Belessi, Kostas Stamatopoulos
Journal: Blood
Blood (2012) 120 (21): 3862.
https://doi.org/10.1182/blood.V120.21.3862.3862
Published: 2012
Journal Articles

Differential Functional Outcomes After Stimulation Via Innate Immunity Receptors In Chronic Lymphocytic Leukemia Subtypes Defined by the Molecular Features of the Immunoglobulin Receptor

Stavroula Ntoufa, Anna Vardi, Nikos Papakonstantinou, Achilles Anagnostopoulos, Vassiliki Aleporou-Marinou, Federico Caligaris-Cappio, M.D., Chrysoula Belessi, Paolo Ghia, Marta Muzio, Kostas Stamatopoulos
Journal: Blood
Blood (2010) 116 (21): 374.
https://doi.org/10.1182/blood.V116.21.374.374
Published: 2010
Journal Articles

Toll-Like Receptor Signaling Pathway In Chronic Lymphocytic Leukemia: Distinct Gene Expression Profiles of Potential Pathogenetic Significance In Specific Subsets of Patients

Eleni Arvaniti, Stavroula Ntoufa, Nikos Papakonstantinou, Tasoula Touloumenidou, Nikolaos Laoutaris, Achilles Anagnostopoulos, Kleoniki Lamnisou, Federico Caligaris-Cappio, M.D., Kostas Stamatopoulos, Paolo Ghia, Marta Muzio, Chrysoula Belessi
Journal: Blood
Blood (2010) 116 (21): 44.
https://doi.org/10.1182/blood.V116.21.44.44
Published: 2010