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Journal Articles

First Disclosure of AZD9829, a TOP1i-ADC Targeting CD123: Promising Preclinical Activity in AML Models with Minimal Effect on Healthy Progenitors

Blood (2023) 142 (Supplement 1): 5957.

https://doi.org/10.1182/blood-2023-187642

Published: 2023

Journal Articles

Novel DNA-Damaging Linker Payloads Are Active in Models of Acquired Resistance to Calicheamicin and Standard of Care

Jennifer Kahler, Maureen Dougher, Jia Lu, MS, Jane Xu, MS, Tasneem Kausar, PhD, Luanna Lemon, Wenyan Zhong, PhD, Judy Lucas, Matthew Sung, PhD, Puja Sapra, PhD

Blood (2016) 128 (22): 3522.

https://doi.org/10.1182/blood.V128.22.3522.3522

Published: 2016

Journal Articles

Marked Therapeutic Efficacy of a Novel Polyethyleneglycol-SN38 Conjugate, EZN-2208, in Xenograft Models of Non-Hodgkin’s Lymphoma.

Puja Sapra, PhD, Mary Mehlig, BS, Jennifer Malaby, BS, Patricia Kraft, MS, Clifford Longley, MS, Hong Zhao, PhD, Lee M. Greenberger, PhD, Ivan D. Horak, MD

Blood (2007) 110 (11): 1397.

https://doi.org/10.1182/blood.V110.11.1397.1397

Published: 2007

Journal Articles

Recombinant Human Mannose-Binding Lectin (rhMBL) Binds to Human and Mouse Cancer Cells and Elicits Antitumor Activity in a MBL Knockout Mouse Model of Murine Cancer.

Puja Sapra, PhD, Patricia Kraft, MS, Mary Mehlig, BS, Zhihua Zhang, MD,PhD, Lee M. Greenberger, PhD, Ivan D. Horak, MD

Blood (2006) 108 (11): 1259.

https://doi.org/10.1182/blood.V108.11.1259.1259

Published: 2006

Journal Articles

Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/anti-CD74 humanized IgG 4 antibody immunotoxin

Chien-Hsing Chang, Puja Sapra, Sailaja S. Vanama, Hans J. Hansen, Ivan D. Horak, David M. Goldenberg

Blood (2005) 106 (13): 4308–4314.

https://doi.org/10.1182/blood-2005-03-1033

Published: 2005

Journal Articles

Preclinical Safety and Efficacy of Two Novel Immunotoxins Consisting of Ranpirnase (Rap) Fused to an Internalizing Anti-CD74 Humanized IgG4 Antibody in Human Non-Hodgkin’s Lymphoma Xenografts.

Puja Sapra, PhD, Chien-Hsing Chang, Ph.D, Sailaja Vanama, Ph.D, Sharon Singh, BA, Hans J. Hansen, Ph.D, Ivan D. Horak, M.D, David M. Goldenberg, M.D

Blood (2005) 106 (11): 346.

https://doi.org/10.1182/blood.V106.11.346.346

Published: 2005

Journal Articles

Initial Safety and Efficacy Results of a Second-Generation Humanized Anti-CD20 Antibody, IMMU-106 (hA20), in Non-Hodgkin’s Lymphoma.

Franck Morschhauser, John P. Leonard, Bertrand Coiffier, Marie-Odile Petillon, Morton Coleman, Amina Bahkti, Puja Sapra, Nick Teoh, William A. Wegener, Ivan D. Horak, David M. Goldenberg

Blood (2005) 106 (11): 2428.

https://doi.org/10.1182/blood.V106.11.2428.2428

Published: 2005

Journal Articles

Preclinical Pharmacology and Toxicology of Humanized Anti-B-Cell Antibodies (Anti-CD22 and Anti-CD20) in Cynomolgus Monkeys (CM).

Puja Sapra, PhD, Gary Kikuchi, Ph.D, Ashwini Venkatasamy, BS, Marianne K. Hayes, Ph.D, Christina M. Satterwhite, Ph.D, Darren Warren, Ph.D, Mark D. Walker, DVM, David M. Goldenberg, M.D, Ivan D. Horak, M.D

Blood (2005) 106 (11): 1471.

https://doi.org/10.1182/blood.V106.11.1471.1471

Published: 2005

Journal Articles

In Vitro and In Vivo Targeting and Therapy of an Antibody-Drug Conjugate (IMMU-110) in B-Cell Malignancies.

Puja Sapra, PhD, Rhona Stein, PhD, Jennifer Pickett, PhD, Serengulam V. Govindan, PhD, Thomas M. Cardillo, PhD, Christopher Damoci, BS, Agatha Sheerin, BS, Hans J. Hansen, PhD, Ivan D. Horak, MD, Gary L. Griffiths, PhD, David M. Goldenberg, ScD, MD

Blood (2004) 104 (11): 3287.

https://doi.org/10.1182/blood.V104.11.3287.3287

Published: 2004

Journal Articles

Construction and Characterization of a Novel Ribonuclease Immunotoxin Consisting of Two Ranpirnase (Rap) Molecules Fused to an Internalizing Anti-CD74 Humanized IgG4 Antibody.

Sailaja S. Vanama, PhD, Puja Sapra, PhD, Hans J. Hansen, PhD, Ivan D. Horak, MD, David M. Goldenberg, ScD, MD, Chien-Hsing Chang, PhD

Blood (2004) 104 (11): 3289.

https://doi.org/10.1182/blood.V104.11.3289.3289

Published: 2004

NARROW

First Disclosure of AZD9829, a TOP1i-ADC Targeting CD123: Promising Preclinical Activity in AML Models with Minimal Effect on Healthy Progenitors

Novel DNA-Damaging Linker Payloads Are Active in Models of Acquired Resistance to Calicheamicin and Standard of Care

Marked Therapeutic Efficacy of a Novel Polyethyleneglycol-SN38 Conjugate, EZN-2208, in Xenograft Models of Non-Hodgkin’s Lymphoma.

Recombinant Human Mannose-Binding Lectin (rhMBL) Binds to Human and Mouse Cancer Cells and Elicits Antitumor Activity in a MBL Knockout Mouse Model of Murine Cancer.

Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/anti-CD74 humanized IgG 4 antibody immunotoxin

Preclinical Safety and Efficacy of Two Novel Immunotoxins Consisting of Ranpirnase (Rap) Fused to an Internalizing Anti-CD74 Humanized IgG4 Antibody in Human Non-Hodgkin’s Lymphoma Xenografts.

Initial Safety and Efficacy Results of a Second-Generation Humanized Anti-CD20 Antibody, IMMU-106 (hA20), in Non-Hodgkin’s Lymphoma.

Preclinical Pharmacology and Toxicology of Humanized Anti-B-Cell Antibodies (Anti-CD22 and Anti-CD20) in Cynomolgus Monkeys (CM).

In Vitro and In Vivo Targeting and Therapy of an Antibody-Drug Conjugate (IMMU-110) in B-Cell Malignancies.

Construction and Characterization of a Novel Ribonuclease Immunotoxin Consisting of Two Ranpirnase (Rap) Molecules Fused to an Internalizing Anti-CD74 Humanized IgG4 Antibody.

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American Society of Hematology

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American Society of Hematology

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